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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3441
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pthlh
Name: parathyroid hormone-like hormone
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pthlhmultiple interactionsISOPTHLH (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PTHLH mRNA; [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in decreased expression of PTHLH mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PTHLH mRNAPMID:32699268 PMID:32845096
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