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GENE - TERM ANNOTATION REPORT

RGD ID: 3441
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pthlh
Name: parathyroid hormone-like hormone
Acc ID: GO:0007189
Term: adenylate cyclase-activating G protein-coupled receptor signaling pathway
Definition: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pthlh IDA 729903RGD  
Pthlhacts_upstream_of_or_withinISOPTHLH (Homo sapiens)1624291RGD PMID:9832460

PMID:9832460
Pthlhinvolved_inIEAUniProtKB:P12272 or ensembl:ENSP000004417651600115EnsemblGO_REF:0000107

GO_REF:0000107
Pthlhinvolved_inIBAPANTHER:PTN000425409 or Pthlh (Rattus norvegicus) or UniProtKB:P122721600115GO_CentralGO_REF:0000033

GO_REF:0000033
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