Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pot1 (protection of telomeres 1) Rattus norvegicus
Analyze
Symbol: Pot1
Name: protection of telomeres 1
Description: Predicted to have DEAD/H-box RNA helicase binding activity; DNA binding activity; and telomerase inhibitor activity. Predicted to be involved in several processes, including positive regulation of DNA helicase activity; regulation of DNA metabolic process; and telomere organization. Predicted to localize to the shelterin complex. Human ortholog(s) of this gene implicated in familial melanoma and malignant glioma. Orthologous to human POT1 (protection of telomeres 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hypothetical protein LOC500054; LOC500054; Pot1a; protection of telomeres 1 homolog; protection of telomeres 1 homolog (S. pombe); protection of telomeres 1A; protection of telomeres protein 1; similar to POT1-like telomere end-binding protein
Orthologs:
Homo sapiens (human) : POT1 (protection of telomeres 1)  HGNC  Alliance
Mus musculus (house mouse) : Pot1a (protection of telomeres 1A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pot1 (protection of telomeres 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POT1 (protection of telomeres 1)
Canis lupus familiaris (dog) : POT1 (protection of telomeres 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pot1 (protection of telomeres 1)
Sus scrofa (pig) : POT1 (protection of telomeres 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0451,888,632 - 51,946,764 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0451,664,672 - 51,722,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4452,233,404 - 52,289,574 (-)NCBIRGSC3.4rn4RGSC3.4
Celera449,343,691 - 49,398,232 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pot1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562696
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.