Pot1 (protection of telomeres 1) - Rat Genome Database

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Gene: Pot1 (protection of telomeres 1) Chinchilla lanigera
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Symbol: Pot1
Name: protection of telomeres 1
RGD ID: 8705185
Description: ENCODES a protein that exhibits 8-hydroxy-2'-deoxyguanosine DNA binding (ortholog); DEAD/H-box RNA helicase binding (ortholog); G-rich single-stranded DNA binding (ortholog); INVOLVED IN chromosome organization (ortholog); DNA duplex unwinding (ortholog); establishment of protein localization to telomere (ortholog); ASSOCIATED WITH aplastic anemia (ortholog); Cerebroretinal Microangiopathy with Calcifications and Cysts 3 (ortholog); cholecystitis (ortholog); FOUND IN chromosome, telomeric region (ortholog); nuclear telomere cap complex (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protection of telomeres protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554796,140,501 - 6,209,031 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554796,140,599 - 6,230,512 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pot1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554796,140,501 - 6,209,031 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554796,140,599 - 6,230,512 (-)NCBIChiLan1.0ChiLan1.0
POT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387124,822,386 - 124,929,825 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7124,822,386 - 124,929,983 (-)EnsemblGRCh38hg38GRCh38
GRCh377124,462,440 - 124,569,879 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367124,249,676 - 124,357,273 (-)NCBINCBI36Build 36hg18NCBI36
Build 347124,057,263 - 124,131,201NCBI
Celera7119,267,687 - 119,375,230 (-)NCBICelera
Cytogenetic Map7q31.33NCBI
HuRef7118,827,419 - 118,935,017 (-)NCBIHuRef
CHM1_17124,395,753 - 124,503,350 (-)NCBICHM1_1
T2T-CHM13v2.07126,139,780 - 126,247,229 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27123,851,834 - 123,959,412 (-)NCBI
Pot1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39625,743,939 - 25,809,280 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl625,743,736 - 25,809,245 (-)EnsemblGRCm39 Ensembl
GRCm38625,743,940 - 25,809,277 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl625,743,737 - 25,809,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv37625,693,735 - 25,759,226 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36625,693,745 - 25,759,236 (-)NCBIMGSCv36mm8
Celera625,744,313 - 25,810,007 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map611.65NCBI
Pot1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8455,170,821 - 55,228,588 (-)NCBIGRCr8
mRatBN7.2454,205,330 - 54,263,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl454,205,332 - 54,263,042 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx459,206,940 - 59,263,878 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0455,120,524 - 55,177,464 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0453,525,039 - 53,581,975 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0451,888,632 - 51,946,764 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl451,888,634 - 51,946,715 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0451,664,672 - 51,722,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4452,233,404 - 52,289,574 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera449,343,691 - 49,398,232 (-)NCBICelera
Cytogenetic Map4q22NCBI
POT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26161,671,016 - 161,789,306 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1713,677,851 - 13,799,556 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07116,807,913 - 116,926,998 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17129,487,571 - 129,605,558 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7129,487,571 - 129,605,558 (-)Ensemblpanpan1.1panPan2
POT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11410,987,385 - 11,067,473 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1410,987,494 - 11,066,956 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1410,683,957 - 10,766,907 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01410,769,382 - 10,849,644 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1410,769,491 - 10,849,644 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11410,960,833 - 11,041,479 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01410,693,633 - 10,773,611 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01410,852,699 - 10,933,293 (+)NCBIUU_Cfam_GSD_1.0
Pot1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511851,284,826 - 51,367,106 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936605836,769 - 920,201 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936605836,824 - 919,099 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1822,885,749 - 22,981,890 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11822,885,704 - 22,981,893 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21824,394,687 - 24,526,564 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12193,572,139 - 93,688,374 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2193,571,272 - 93,655,869 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660429,761,660 - 9,885,572 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pot1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478311,138,303 - 11,223,044 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478311,138,222 - 11,223,329 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSCLAT00000006394   ⟹   ENSCLAP00000006290
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554796,140,501 - 6,209,031 (-)Ensembl
RefSeq Acc Id: XM_005402344   ⟹   XP_005402401
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554796,140,599 - 6,227,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402345   ⟹   XP_005402402
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554796,140,599 - 6,212,740 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402346   ⟹   XP_005402403
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554796,140,599 - 6,230,395 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013503293   ⟹   XP_013358747
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554796,140,599 - 6,230,512 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001230883
Type: NON-CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554796,140,865 - 6,230,512 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005402401 (Get FASTA)   NCBI Sequence Viewer  
  XP_005402402 (Get FASTA)   NCBI Sequence Viewer  
  XP_005402403 (Get FASTA)   NCBI Sequence Viewer  
  XP_013358747 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006290
  ENSCLAP00000006290.1
RefSeq Acc Id: XP_005402403   ⟸   XM_005402346
- UniProtKB: A0A8C2UW33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005402401   ⟸   XM_005402344
- UniProtKB: A0A8C2UW33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005402402   ⟸   XM_005402345
- UniProtKB: A0A8C2UW33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013358747   ⟸   XM_013503293
- UniProtKB: A0A8C2UW33 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000006290   ⟸   ENSCLAT00000006394

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004448 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006394 ENTREZGENE
  ENSCLAT00000006394.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
InterPro NA-bd_OB-fold UniProtKB/TrEMBL
  POT1 UniProtKB/TrEMBL
  POT1_C_insert UniProtKB/TrEMBL
  POT1PC UniProtKB/TrEMBL
  Telomer_end-bd_POT1/Cdc13 UniProtKB/TrEMBL
NCBI Gene Pot1 ENTREZGENE
PANTHER PROTECTION OF TELOMERES PROTEIN 1 UniProtKB/TrEMBL
  PTHR14513 UniProtKB/TrEMBL
Pfam POT1 UniProtKB/TrEMBL
  POT1_C_insert UniProtKB/TrEMBL
  POT1PC UniProtKB/TrEMBL
SMART Telo_bind UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
UniProt A0A8C2UW33 ENTREZGENE, UniProtKB/TrEMBL