Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:allylic alcohol
go back to main search page
Accession:CHEBI:134361 term browser browse the term
Definition:An alcohol where the hydroxy group is attached to a saturated carbon atom adjacent to a double bond (R groups may be H, organyl, etc.).
Synonyms:related_synonym: Formula=C3HOR5;   SMILES=C(C(=C(*)*)*)(O)(*)*;   allylic alcohols



show annotations for term's descendants           Sort by:
(+)-abscisic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 increases secretion
multiple interactions
ISO CCL2 protein results in increased secretion of Abscisic Acid
fluridone inhibits the reaction [CCL2 protein results in increased secretion of Abscisic Acid]
CTD PMID:24211328 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
(+)-artemisinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions
ISO [artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of CEBPA mRNA
[[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA] which results in decreased chemical synthesis of Cholesterol
CTD PMID:23063590 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Dct dopachrome tautomerase decreases expression ISO artemisic acid results in decreased expression of DCT mRNA CTD PMID:23063590 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases expression
ISO [[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA] which results in decreased chemical synthesis of Cholesterol; [artemisic acid results in decreased expression of HMGCR protein] which results in decreased chemical synthesis of Cholesterol
[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of HMGCR protein
CTD PMID:23063590 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO artemisic acid results in decreased expression of KIT mRNA CTD PMID:23063590 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Kitlg KIT ligand decreases expression ISO artemisic acid results in decreased expression of KITLG mRNA CTD PMID:23063590 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Mif macrophage migration inhibitory factor decreases expression ISO artemisic acid results in decreased expression of MIF mRNA CTD PMID:23063590 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO artemisic acid results in decreased expression of MITF mRNA CTD PMID:23063590 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Tyr tyrosinase decreases expression ISO artemisic acid results in decreased expression of TYR mRNA CTD PMID:23063590 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO artemisic acid results in decreased expression of TYRP1 mRNA CTD PMID:23063590 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] promotes the reaction [Silver Compounds results in decreased expression of ALOX15 mRNA]] CTD PMID:34601004 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases expression
multiple interactions
ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid results in decreased expression of ALOX5 protein
17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[[Dietary Fats co-treated with Cholesterol, Dietary] results in increased susceptibility to Silver Compounds] which results in decreased expression of ALOX5 mRNA]
CTD PMID:17056761 PMID:34601004 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] promotes the reaction [Silver Compounds results in increased expression of CCL2 mRNA]]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] promotes the reaction [Silver Compounds results in increased expression of CCL2 protein]]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Silver Compounds results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased expression of CCL2 mRNA]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Silver Compounds results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased expression of CCL2 protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Silver Compounds results in increased expression of CCL2 mRNA]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Silver Compounds results in increased expression of CCL2 protein] CTD PMID:21724996 PMID:34601004 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] promotes the reaction [Silver Compounds results in increased expression of CXCL2 mRNA]]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] promotes the reaction [Silver Compounds results in increased expression of CXCL2 protein]]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Silver Compounds results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased expression of CXCL2 mRNA]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Silver Compounds results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased expression of CXCL2 protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Silver Compounds results in increased expression of CXCL2 mRNA]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Silver Compounds results in increased expression of CXCL2 protein]; [Silver Compounds results in increased susceptibility to 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid] which results in increased expression of CXCL2 mRNA CTD PMID:21724996 PMID:34601004 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein] CTD PMID:21724996 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA] CTD PMID:21724996 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] CTD PMID:21724996 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein] CTD PMID:21724996 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] promotes the reaction [Silver Compounds results in increased expression of IL6 mRNA]]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] promotes the reaction [Silver Compounds results in increased expression of IL6 protein]]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Silver Compounds results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased expression of IL6 mRNA]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [[Silver Compounds results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased expression of IL6 protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Silver Compounds results in increased expression of IL6 mRNA]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Silver Compounds results in increased expression of IL6 protein] CTD PMID:21724996 PMID:34601004 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA] CTD PMID:21724996 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21724996 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:21724996 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid binds to and affects the activity of PPARG protein CTD PMID:17056761 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21724996 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein] CTD PMID:21724996 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases secretion
ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid results in decreased secretion of TNF protein
CTD PMID:17056761 PMID:21724996 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA] CTD PMID:21724996 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
16,16-dimethylprostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO 16,16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein
EGFR affects the reaction [16,16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein]
CTD PMID:15578100 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance
affects localization
ISO BAX results in increased susceptibility to 16,16-Dimethylprostaglandin E2
16,16-Dimethylprostaglandin E2 affects the localization of BAX protein
CTD PMID:15578100 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO EGFR affects the reaction [16,16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein] CTD PMID:15578100 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases activity ISO 16,16-Dimethylprostaglandin E2 results in increased activity of HPGD protein CTD PMID:14736730 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 PMID:11855677 PMID:11991626 PMID:18306037 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:11686837 PMID:11855677 PMID:11991626 PMID:15610444 PMID:18306037 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
Flurbiprofen inhibits the reaction [16,16-Dimethylprostaglandin E2 results in increased expression of PTGS2 mRNA]
16,16-Dimethylprostaglandin E2 inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA]
CTD PMID:9099957 PMID:15610444 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 16,16-Dimethylprostaglandin E2 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF] CTD PMID:9298541 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
all-trans-4-hydroxyretinoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases chemical synthesis ISO CYP1A1 protein results in increased chemical synthesis of 4-hydroxyretinoic acid CTD PMID:10874126 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases metabolic processing
multiple interactions
increases chemical synthesis
increases expression
ISO CYP26A1 protein results in increased metabolism of 4-hydroxyretinoic acid
[[Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; [[R 115866 results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; [CYP26A1 protein results in increased metabolism of Tretinoin] which results in increased chemical synthesis of 4-hydroxyretinoic acid; [Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; [R 115866 results in decreased activity of CYP26A1 protein] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased chemical synthesis of 4-hydroxyretinoic acid]
CYP26A1 mRNA results in increased chemical synthesis of 4-hydroxyretinoic acid; CYP26A1 protein results in increased chemical synthesis of 4-hydroxyretinoic acid
4-hydroxyretinoic acid results in increased expression of CYP26A1 mRNA
CTD PMID:12091498 PMID:17460545 PMID:25492813 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases chemical synthesis ISO CYP2C8 protein results in increased chemical synthesis of 4-hydroxyretinoic acid CTD PMID:10874126
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases chemical synthesis ISO CYP3A4 protein results in increased chemical synthesis of 4-hydroxyretinoic acid CTD PMID:10874126 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming increases expression ISO 4-hydroxyretinoic acid results in increased expression of MUC2 mRNA CTD PMID:10953040 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO 4-hydroxyretinoic acid results in increased expression of MUC5AC mRNA CTD PMID:10953040 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO 4-hydroxyretinoic acid results in increased activity of RARA protein CTD PMID:25492813 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta increases activity
increases expression
ISO 4-hydroxyretinoic acid results in increased activity of RARB protein
4-hydroxyretinoic acid results in increased expression of RARB mRNA
CTD PMID:25492813 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma increases activity ISO 4-hydroxyretinoic acid results in increased activity of RARG protein CTD PMID:25492813 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
all-trans-4-oxoretinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 affects expression ISO 4-oxoretinol affects the expression of CDH1 mRNA CTD PMID:17034753 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO 4-oxoretinol results in increased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO 4-oxoretinol results in increased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO 4-oxoretinol results in increased expression of CRABP2 mRNA CTD PMID:17034753 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects chemical synthesis ISO CYP26A1 protein affects the chemical synthesis of 4-oxoretinol CTD PMID:10557354 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 4-oxoretinol results in decreased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Foxa1 forkhead box A1 increases expression ISO 4-oxoretinol results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO 4-oxoretinol results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO 4-oxoretinol results in increased expression of ITGAM protein CTD PMID:9581846 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Ivl involucrin increases expression ISO 4-oxoretinol results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Krt18 keratin 18 increases expression ISO 4-oxoretinol results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt19 keratin 19 increases expression ISO 4-oxoretinol results in increased expression of KRT19 mRNA CTD PMID:17034753 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt7 keratin 7 increases expression ISO 4-oxoretinol results in increased expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt8 keratin 8 increases expression ISO 4-oxoretinol results in increased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO 4-oxoretinol results in decreased expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Meis1 Meis homeobox 1 increases expression ISO 4-oxoretinol results in increased expression of MEIS1 mRNA CTD PMID:17034753 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
JBrowse link
G Meis2 Meis homeobox 2 increases expression ISO 4-oxoretinol results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO 4-oxoretinol results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO 4-oxoretinol results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO 4-oxoretinol results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO 4-oxoretinol results in increased expression of RARA mRNA CTD PMID:17034753 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO 4-oxoretinol results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO 4-oxoretinol results in increased expression of TGM2 mRNA CTD PMID:17034753 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
all-trans-retinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA]
Vitamin A results in decreased expression of ABCB1 mRNA; Vitamin A results in decreased expression of ABCB1A mRNA
CTD PMID:15327746 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression ISO Vitamin A results in increased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP Vitamin A deficiency results in decreased expression of ACSS2 mRNA CTD PMID:12163651 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Vitamin A inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:16256175 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta decreases expression EXP Vitamin A deficiency results in decreased expression of ACTB mRNA CTD PMID:12163651 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression
multiple interactions
EXP Vitamin A results in decreased expression of ACTG2 protein
Vitamin A results in decreased expression of [Ethanol results in increased expression of ACTG2 protein]
CTD PMID:16043492 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Afp alpha-fetoprotein increases expression EXP Vitamin A deficiency results in increased expression of AFP mRNA CTD PMID:7519440 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased expression of AGER protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased expression of AGER protein]; [Vitamin A results in increased abundance of Reactive Oxygen Species] which results in increased expression of AGER protein; SB 203580 inhibits the reaction [Vitamin A results in increased expression of AGER protein] CTD PMID:18396385 PMID:21807062 PMID:22274401 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA] CTD PMID:15728703 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases response to substance ISO AKR1B1 protein results in decreased susceptibility to Vitamin A; AKR1B1 protein results in decreased susceptibility to Vitamin A metabolite CTD PMID:19014918 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases response to substance ISO AKR1B10 protein results in decreased susceptibility to Vitamin A; AKR1B10 protein results in decreased susceptibility to Vitamin A metabolite CTD PMID:19014918 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of AKT1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of AKT1 protein] CTD PMID:21807062 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin affects binding ISO Vitamin A binds to ALB protein CTD PMID:17184834 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Vitamin A results in decreased expression of ALDH1A2 mRNA CTD PMID:30944279 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Vitamin A] results in increased activity of AOX1 protein; [Tetrachlorodibenzodioxin co-treated with Vitamin A] results in increased expression of AOX1 mRNA; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AOX1 protein]; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AOX1 mRNA] CTD PMID:16292751 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Apod apolipoprotein D affects binding ISO Vitamin A binds to APOD protein CTD PMID:16461020 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression
affects expression
EXP Tretinoin inhibits the reaction [Vitamin A affects the expression of APP mRNA]
Vitamin A results in increased expression of APP protein
CTD PMID:16530976 PMID:22274401 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression EXP Vitamin A deficiency results in increased expression of ASCL1 mRNA CTD PMID:12555267 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Bace1 beta-secretase 1 multiple interactions
affects expression
EXP Tretinoin inhibits the reaction [Vitamin A affects the expression of BACE mRNA] CTD PMID:16530976 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Vitamin A results in increased expression of BAX protein CTD PMID:16216918 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Vitamin A results in decreased expression of BCL2 protein CTD PMID:16216918 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression ISO Vitamin A affects the expression of BMP4 mRNA CTD PMID:16120438 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Vitamin A results in increased expression of BTG2 mRNA CTD PMID:17234770 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cab39 calcium binding protein 39 decreases expression EXP Vitamin A deficiency results in decreased expression of CAB39 mRNA CTD PMID:12163651 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
increases activity
ISO alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein]
Vitamin A results in decreased activity of CASP3 protein
CTD PMID:16531423 PMID:17618090 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase affects activity
decreases activity
increases expression
multiple interactions
decreases expression
ISO
EXP
Vitamin A affects the activity of CAT protein
Vitamin A results in decreased activity of CAT protein
Vitamin A results in increased expression of CAT protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased expression of CAT protein]; [Vitamin A results in decreased activity of CAT protein] which results in increased abundance of Hydrogen Peroxide; Vitamin A results in increased expression of and results in increased activity of CAT protein
Vitamin A deficiency results in decreased expression of CAT protein; Vitamin A results in decreased expression of CAT protein
CTD PMID:8602878 PMID:16036340 PMID:17673185 PMID:17727954 PMID:18440196 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
increases expression
affects expression
ISO
EXP
Vitamin A results in decreased expression of CCL2 protein
Vitamin A results in increased expression of CCL2 mRNA
Vitamin A affects the expression of CCL2 protein
CTD PMID:16988133 PMID:25051504 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Vitamin A results in decreased expression of CCND1 mRNA CTD PMID:17219422 PMID:17234770 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression EXP Vitamin A deficiency results in decreased expression of CCND2 mRNA CTD PMID:12163651 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd14 CD14 molecule increases expression ISO Vitamin A results in increased expression of CD14 mRNA CTD PMID:17033190 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd44 CD44 molecule increases expression ISO Vitamin A results in increased expression of CD44 protein CTD PMID:16724877 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdh1 cadherin 1 affects expression ISO Vitamin A affects the expression of CDH1 mRNA CTD PMID:17034753 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO Vitamin A results in increased expression of COL1A1 mRNA
[Cryptoxanthins co-treated with Vitamin A] results in increased expression of COL1A1 mRNA
CTD PMID:15962303 PMID:17034753 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA] CTD PMID:16397886 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO Vitamin A results in increased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions
increases expression
ISO CRABP2 protein promotes the reaction [Vitamin A results in increased expression of TOB1 mRNA]
Vitamin A results in increased expression of CRABP2 mRNA
CTD PMID:16793012 PMID:17034753 PMID:17234770 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
ISO
EXP
Vitamin A results in increased phosphorylation of CREB1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]
CTD PMID:16280361 PMID:16510265 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; MG 262 inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; Vitamin A results in increased ubiquitination of and results in increased degradation of CTNNB1 protein CTD PMID:17219422 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cycs cytochrome c, somatic affects localization EXP Vitamin A affects the localization of CYCS protein CTD PMID:16202537 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:15728703 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases oxidation
decreases activity
ISO CYP1B1 protein results in increased oxidation of Vitamin A
Vitamin A results in decreased activity of CYP1B1 protein
CTD PMID:15258110 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions
increases expression
affects metabolic processing
ISO
EXP
[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA
Vitamin A results in increased expression of CYP26A1 mRNA
[R 115866 co-treated with Vitamin A] results in increased expression of CYP26A1 mRNA
CYP26A1 protein affects the metabolism of Vitamin A
CTD PMID:10557354 PMID:16194896 PMID:17244623 PMID:17510468 PMID:22542753 More... NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions EXP [R 115866 co-treated with Vitamin A] results in increased expression of CYP26B1 mRNA CTD PMID:17510468 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein]; Vitamin A affects the expression of and affects the activity of CYP2C11 protein CTD PMID:15963505 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Dcp2 decapping mRNA 2 decreases expression EXP Vitamin A deficiency results in decreased expression of DCP2 mRNA CTD PMID:12163651 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] CTD PMID:16214399 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dhh desert hedgehog signaling molecule multiple interactions EXP Vitamin A inhibits the reaction [Valproic Acid results in increased expression of DHH mRNA] CTD PMID:35594946 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases abundance ISO DHRS3 gene mutant form results in decreased abundance of Vitamin A CTD PMID:24005908 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases metabolic processing ISO DHRS9 protein results in increased metabolism of Vitamin A CTD PMID:11304534 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP Vitamin A results in decreased expression of DRD2 protein CTD PMID:22274401 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression EXP Vitamin A deficiency results in decreased expression of EEF1A1 mRNA CTD PMID:12163651 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP Vitamin A deficiency results in increased expression of EGFR mRNA CTD PMID:7519440 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression EXP Vitamin A deficiency results in decreased expression of EIF4A2 mRNA CTD PMID:12163651 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Epo erythropoietin increases expression
multiple interactions
ISO
EXP
Vitamin A results in increased expression of EPO protein
Vitamin A inhibits the reaction [Hydrogen Peroxide results in decreased expression of EPO protein]
CTD PMID:9927288 PMID:16960172 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Vitamin A inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:19340624 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Vitamin A results in decreased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fn1 fibronectin 1 decreases secretion ISO Vitamin A results in decreased secretion of FN1 protein CTD PMID:17225872 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fnta farnesyltransferase, CAAX box, subunit alpha multiple interactions EXP [Vitamin A co-treated with perillyl alcohol] results in decreased expression of FNTA protein CTD PMID:15959631 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Fntb farnesyltransferase, CAAX box, subunit beta multiple interactions
increases expression
EXP [perillyl alcohol co-treated with Vitamin A] results in decreased expression of FNTB mRNA
Vitamin A results in increased expression of FNTB mRNA; Vitamin A results in increased expression of FNTB protein
CTD PMID:15959631 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
JBrowse link
G Foxa1 forkhead box A1 increases expression ISO Vitamin A results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP Vitamin A inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein] CTD PMID:16863852 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
decreases expression
EXP Iron deficiency promotes the reaction [Vitamin A deficiency results in decreased expression of FTH1 protein]
Vitamin A deficiency results in decreased expression of FTH1 mRNA; Vitamin A deficiency results in decreased expression of FTH1 protein
CTD PMID:22154532 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression ISO Vitamin A results in increased expression of GABRB3 mRNA CTD PMID:17225872 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO Vitamin A results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Gcg glucagon multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of GCG mRNA CTD PMID:17244017 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein] CTD PMID:15963505 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
EXP Vitamin A inhibits the reaction [nitrofen results in increased expression of GJA1 mRNA]
Vitamin A results in increased expression of GJA1 mRNA
CTD PMID:12031251 PMID:16292552 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gnai1 G protein subunit alpha i1 increases expression EXP Vitamin A results in increased expression of GNAI1 protein CTD PMID:16757122 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression EXP Vitamin A results in increased expression of GNAI2 protein CTD PMID:16757122 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
EXP Vitamin A results in increased activity of GPT protein
gadolinium chloride inhibits the reaction [Vitamin A results in increased activity of GPT protein]
CTD PMID:8627517 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Vitamin A co-treated with Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 protein CTD PMID:17179735 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grhl3 grainyhead-like transcription factor 3 increases response to substance ISO GRHL3 gene mutant form results in increased susceptibility to Vitamin A CTD PMID:6635991 NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Vitamin A inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G H3f4 H3.4 histone, cluster member multiple interactions
increases acetylation
ISO Vitamin A affects the reaction [H3F4 protein modified form binds to PCK1 promoter]
Vitamin A results in increased acetylation of H3F4 protein
CTD PMID:16317119 NCBI chr10:43,740,702...43,741,262 JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Vitamin A results in increased expression of HBEGF mRNA CTD PMID:19648781 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hoxa1 homeobox A1 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased expression of HOXA1]; 3,4-methylenedioxy-beta-nitrostyrene inhibits the reaction [Vitamin A results in increased expression of HOXA1]; 4-nonylphenol inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; BAY 11-7085 inhibits the reaction [Vitamin A results in increased expression of HOXA1]; bisphenol A inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Camptothecin inhibits the reaction [Vitamin A results in increased expression of HOXA1]; citral inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; di-n-pentyl phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Dibutyl Phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Diethylstilbestrol inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Genistein inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; nitrofen inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]
Vitamin A results in increased expression of HOXA1; Vitamin A results in increased expression of HOXA1 mRNA
CTD PMID:23696197 PMID:26820057 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
JBrowse link
G Hoxa3 homeobox A3 affects expression ISO Vitamin A affects the expression of HOXA3 mRNA CTD PMID:10992263 NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218
JBrowse link
G Ifng interferon gamma decreases expression
affects expression
ISO
EXP
Vitamin A results in decreased expression of IFNG protein
Vitamin A affects the expression of IFNG protein
CTD PMID:14624943 PMID:17289162 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta increases expression EXP Vitamin A results in increased expression of IL1B protein CTD PMID:25051504 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO Vitamin A results in increased expression of IL2 mRNA CTD PMID:15506942 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 decreases expression ISO Vitamin A results in decreased expression of IL4 protein CTD PMID:14624943 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Inhba inhibin subunit beta A multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in decreased expression of SHH mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of GCG mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of INS1 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of INS2 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PDX1 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PPY mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PTF1A mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of SOX17 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of SST mRNA CTD PMID:17244017 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Ins1 insulin 1 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of INS1 mRNA CTD PMID:17244017 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of INS2 mRNA CTD PMID:17244017 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression EXP Vitamin A deficiency results in increased expression of IREB2 mRNA CTD PMID:22154532 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO Vitamin A results in increased expression of ITGA3 protein CTD PMID:17241391 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgb1 integrin subunit beta 1 affects localization
increases expression
ISO Vitamin A affects the localization of ITGB1 protein
Vitamin A results in increased expression of ITGB1 protein
CTD PMID:17241391 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Ivl involucrin increases expression ISO Vitamin A results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jak2 Janus kinase 2 affects localization EXP Vitamin A affects the localization of JAK2 protein CTD PMID:15963505 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Krt18 keratin 18 increases expression ISO Vitamin A results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt19 keratin 19 increases expression
decreases expression
ISO
EXP
Vitamin A results in increased expression of KRT19 mRNA
Vitamin A deficiency results in decreased expression of KRT19 mRNA
CTD PMID:12163651 PMID:17034753 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt7 keratin 7 increases expression ISO Vitamin A results in increased expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt8 keratin 8 increases expression ISO Vitamin A results in increased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lep leptin multiple interactions EXP LEP gene mutant form promotes the reaction [Vitamin A results in increased expression of UCP1 mRNA] CTD PMID:16493122 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lrat lecithin retinol acyltransferase multiple interactions
decreases expression
affects expression
increases expression
ISO
EXP
[STRA6 protein co-treated with LRAT protein] results in increased uptake of Vitamin A
Vitamin A results in decreased expression of LRAT mRNA
Vitamin A affects the expression of LRAT mRNA
Vitamin A results in increased expression of LRAT mRNA
[Vitamin A co-treated with Tetrachlorodibenzodioxin] results in increased expression of LRAT mRNA; Tetrachlorodibenzodioxin inhibits the reaction [Vitamin A results in increased expression of LRAT mRNA]
CTD PMID:12576510 PMID:16292751 PMID:18316031 PMID:30944279 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Lrp2 LDL receptor related protein 2 multiple interactions ISO LRP2 protein results in increased uptake of and affects the abundance of Vitamin A CTD PMID:16251603 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions
increases phosphorylation
EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein] CTD PMID:16510265 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
increases phosphorylation
EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; Vitamin A results in decreased phosphorylation of and results in decreased activity of MAPK1 protein CTD PMID:16043492 PMID:16510265 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; Vitamin A results in decreased phosphorylation of and results in decreased activity of MAPK3 protein CTD PMID:16043492 PMID:16510265 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mbl2 mannose binding lectin 2 multiple interactions ISO MBL2 gene polymorphism affects the susceptibility to [Vitamin A co-treated with beta Carotene] CTD PMID:16960176 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO Vitamin A affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Meis1 Meis homeobox 1 increases expression
multiple interactions
ISO Vitamin A results in increased expression of MEIS1 mRNA
[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]
CTD PMID:16397886 PMID:17034753 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
JBrowse link
G Meis2 Meis homeobox 2 increases expression
multiple interactions
ISO Vitamin A results in increased expression of MEIS2 mRNA
[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA]
CTD PMID:16397886 PMID:17034753 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO Vitamin A results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression EXP Vitamin A deficiency results in decreased expression of COX3 mRNA CTD PMID:12163651 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO Vitamin A results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Vitamin A results in decreased expression of MYC mRNA CTD PMID:17219422 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Vitamin A affects the reaction [NCOA1 protein binds to PCK1 promoter] CTD PMID:16317119 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Neurog3 neurogenin 3 decreases expression ISO Vitamin A results in decreased expression of NEUROG3 mRNA CTD PMID:30944279 NCBI chr20:30,079,780...30,081,262
Ensembl chr20:30,079,780...30,081,262
JBrowse link
G Nkx2-1 NK2 homeobox 1 multiple interactions ISO
EXP
Vitamin A inhibits the reaction [nitrofen results in decreased expression of NKX2-1 mRNA]
Vitamin A inhibits the reaction [nitrofen results in decreased expression of NKX2-1 protein]
CTD PMID:16490937 PMID:16863852 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Vitamin A deficiency results in increased expression of NOS2 CTD PMID:16036340 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression EXP Vitamin A deficiency results in increased expression of NOS3 CTD PMID:16036340 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases response to substance ISO NPY1R protein results in increased susceptibility to Vitamin A CTD PMID:17400914 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased abundance of Vitamin A] CTD PMID:31449830 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nrgn neurogranin affects expression EXP Vitamin A affects the expression of NRGN mRNA CTD PMID:14529804 NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP Vitamin A deficiency results in decreased expression of ODC1 mRNA CTD PMID:12163651 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Vitamin A results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Oprm1 opioid receptor, mu 1 affects expression EXP Vitamin A affects the expression of OPRM1 mRNA; Vitamin A affects the expression of OPRM1 protein CTD PMID:17289162 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Pax3 paired box 3 multiple interactions EXP Vitamin A inhibits the reaction [nitrofen results in decreased expression of PAX3 mRNA] CTD PMID:16481245 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 affects expression
multiple interactions
ISO Vitamin A affects the expression of PCK1 mRNA
[Tretinoin co-treated with Alitretinoin] affects the reaction [Vitamin A affects the expression of PCK1 mRNA]; Vitamin A affects the reaction [H3F4 protein modified form binds to PCK1 promoter]; Vitamin A affects the reaction [NCOA1 protein binds to PCK1 promoter]; Vitamin A affects the reaction [PPARA protein binds to PCK1 promoter]; Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter]
CTD PMID:16317119 PMID:16713227 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of PDX1 mRNA CTD PMID:17244017 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pomc proopiomelanocortin increases expression EXP Vitamin A results in increased expression of POMC protein CTD PMID:17373634 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Vitamin A affects the reaction [PPARA protein binds to PCK1 promoter] CTD PMID:16713227 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
EXP Vitamin A inhibits the reaction [Safflower Oil results in increased expression of PPARG mRNA]
Vitamin A results in increased expression of PPARG mRNA
CTD PMID:15203375 PMID:16180333 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter] CTD PMID:16317119 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppy pancreatic polypeptide multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of PPY mRNA CTD PMID:17244017 NCBI chr10:87,054,747...87,056,044
Ensembl chr10:87,054,756...87,055,455
JBrowse link
G Prm1 protamine 1 decreases expression ISO Vitamin A results in decreased expression of PRM1 mRNA CTD PMID:30944279 NCBI chr10:4,871,817...4,872,312 JBrowse link
G Ptf1a pancreas associated transcription factor 1a multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of PTF1A mRNA CTD PMID:17244017 NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO Vitamin A binds to PTGDS protein CTD PMID:16461020 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Vitamin A deficiency results in increased expression of PTGS2 CTD PMID:16036340 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 multiple interactions EXP Vitamin A affects the localization of and affects the phosphorylation of PTPN6 protein CTD PMID:15963505 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions
increases expression
ISO
EXP
[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA
[Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RARA protein; [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter]
Vitamin A results in increased expression of RARA mRNA
Vitamin A deficiency results in increased expression of RARA mRNA
[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA]
CTD PMID:7519440 PMID:16397886 PMID:17034753 PMID:17225872 PMID:17244623 More... NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression
affects expression
multiple interactions
increases expression
ISO
EXP
Vitamin A results in decreased expression of RARB mRNA
Vitamin A affects the expression of RARB mRNA
Vitamin A deficiency results in decreased expression of RARB mRNA
[R 115866 co-treated with Vitamin A] results in increased expression of RARB mRNA; Tretinoin inhibits the reaction [Vitamin A affects the expression of RARB mRNA]; Vitamin A inhibits the reaction [Safflower Oil results in decreased expression of RARB mRNA]
Vitamin A results in increased expression of RARB mRNA
CTD PMID:7519440 PMID:14529804 PMID:15203375 PMID:15754000 PMID:16530976 More... NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma multiple interactions ISO RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA] CTD PMID:16397886 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO Vitamin A results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
JBrowse link
G Rbp1 retinol binding protein 1 increases uptake
increases abundance
multiple interactions
affects expression
increases expression
ISO
EXP
RBP1 protein results in increased uptake of Vitamin A
RBP1 gene mutant form results in increased abundance of Vitamin A
[RBP1 gene mutant form results in increased abundance of Vitamin A] which results in increased expression of RBP2 mRNA
Vitamin A affects the expression of RBP1 mRNA
Vitamin A results in increased expression of RBP1 mRNA
CTD PMID:12576510 PMID:16150442 PMID:16793012 PMID:21670153 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
JBrowse link
G Rbp2 retinol binding protein 2 multiple interactions ISO [RBP1 gene mutant form results in increased abundance of Vitamin A] which results in increased expression of RBP2 mRNA CTD PMID:21670153 NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473
JBrowse link
G Rbp4 retinol binding protein 4 affects binding
multiple interactions
increases secretion
decreases secretion
ISO Vitamin A binds to RBP4 protein
Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein
Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]; Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]; Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein
Vitamin A results in increased secretion of RBP4 protein
Vitamin A deficiency results in decreased secretion of RBP4 protein
CTD PMID:16461020 PMID:16762690 PMID:18316031 PMID:21591606 PMID:22001960 More... NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Rdh10 retinol dehydrogenase 10 increases oxidation ISO RDH10 protein results in increased oxidation of Vitamin A CTD PMID:17473173 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572
JBrowse link
G Rdh11 retinol dehydrogenase 11 increases oxidation ISO RDH11 protein results in increased oxidation of Vitamin A CTD PMID:16968212 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
JBrowse link
G Rdh12 retinol dehydrogenase 12 increases chemical synthesis ISO RDH12 protein results in increased chemical synthesis of Vitamin A CTD PMID:16269441 NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388
JBrowse link
G Rdh5 retinol dehydrogenase 5 increases oxidation ISO RDH5 protein results in increased oxidation of Vitamin A CTD PMID:16968212 NCBI chr 7:1,341,172...1,346,863
Ensembl chr 7:1,340,934...1,351,558
JBrowse link
G Ret ret proto-oncogene multiple interactions EXP [Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RET protein; [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter] CTD PMID:32526256 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Retn resistin decreases expression ISO Vitamin A results in decreased expression of RETN mRNA CTD PMID:15047602 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases expression
EXP [perillyl alcohol co-treated with Vitamin A] results in increased expression of RHOA mRNA
Vitamin A results in increased expression of RHOA mRNA
CTD PMID:15959631 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhob ras homolog family member B multiple interactions
increases expression
EXP [perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB mRNA; [perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB protein
Vitamin A results in increased expression of RHOB mRNA; Vitamin A results in increased expression of RHOB protein
CTD PMID:15959631 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rora RAR-related orphan receptor A multiple interactions EXP Vitamin A deficiency promotes the reaction [Valproic Acid results in decreased expression of RORA protein] CTD PMID:33991534 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 increases chemical synthesis
increases metabolic processing
ISO RPE65 protein results in increased chemical synthesis of Vitamin A
RPE65 protein results in increased metabolism of Vitamin A
CTD PMID:16150724 PMID:16828753 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [Cryptoxanthins co-treated with Vitamin A] results in increased expression of RUNX2 mRNA CTD PMID:15962303 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions
increases expression
ISO
EXP
[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA
Vitamin A results in increased expression of RXRA mRNA
Vitamin A results in increased expression of RXRA protein
CTD PMID:16180333 PMID:17219422 PMID:17244623 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta affects expression EXP Vitamin A affects the expression of RXRB mRNA CTD PMID:14529804 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Rxrg retinoid X receptor gamma affects expression
decreases expression
increases expression
EXP
ISO
Vitamin A affects the expression of RXRG mRNA
Vitamin A results in decreased expression of RXRG mRNA
Vitamin A results in increased expression of RXRG protein
CTD PMID:14529804 PMID:17219422 PMID:30944279 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 increases oxidation
increases metabolic processing
ISO SDR16C5 protein results in increased oxidation of Vitamin A
SDR16C5 protein results in increased metabolism of Vitamin A
CTD PMID:18926804 PMID:27793605 NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970
JBrowse link
G Sftpb surfactant protein B multiple interactions EXP
ISO
Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPB mRNA]; Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPB protein] CTD PMID:11588001 PMID:16490937 PMID:16863852 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sftpc surfactant protein C multiple interactions
decreases expression
EXP Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPC mRNA]
Vitamin A results in decreased expression of SFTPC protein
CTD PMID:11588001 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in decreased expression of SHH mRNA CTD PMID:17244017 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions
increases expression
ISO Vitamin A promotes the reaction [Corticosterone results in increased expression of SLC1A2 protein]
Vitamin A results in increased expression of SLC1A2 protein
CTD PMID:17138558 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression EXP Vitamin A deficiency results in decreased expression of SLC30A1 protein CTD PMID:12421840 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc30a2 solute carrier family 30 member 2 multiple interactions EXP [Zinc deficiency co-treated with Vitamin A deficiency] results in increased expression of SLC30A2 mRNA CTD PMID:12421840 NCBI chr 5:146,559,733...146,571,957
Ensembl chr 5:146,559,733...146,571,956
JBrowse link
G Slc30a4 solute carrier family 30 member 4 increases expression EXP Vitamin A deficiency results in increased expression of SLC30A4 mRNA; Vitamin A deficiency results in increased expression of SLC30A4 protein CTD PMID:12421840 NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306
JBrowse link
G Snca synuclein alpha increases expression EXP Vitamin A results in increased expression of SNCA protein CTD PMID:22274401 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sncb synuclein, beta decreases expression EXP Vitamin A results in decreased expression of SNCB protein CTD PMID:22274401 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012
JBrowse link
G Sod1 superoxide dismutase 1 increases activity EXP Vitamin A results in increased activity of SOD1 protein CTD PMID:22274401 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases activity EXP Vitamin A results in increased activity of SOD2 protein CTD PMID:22274401 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox17 SRY-box transcription factor 17 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of SOX17 mRNA CTD PMID:17244017 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions ISO [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA] CTD PMID:16397886 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation
EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein] CTD PMID:16510265 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Sst somatostatin multiple interactions
affects expression
ISO
EXP
[Vitamin A co-treated with INHBA protein] results in increased expression of SST mRNA
Vitamin A affects the expression of SST protein
CTD PMID:16757122 PMID:17244017 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects expression EXP Vitamin A affects the expression of STAT3 protein CTD PMID:15963505 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions EXP Vitamin A affects the phosphorylation of and affects the localization of STAT5A protein CTD PMID:15963505 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 multiple interactions
increases transport
ISO [STRA6 protein co-treated with LRAT protein] results in increased uptake of Vitamin A
STRA6 protein results in increased transport of Vitamin A
CTD PMID:18316031 NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860
JBrowse link
G Stra8 stimulated by retinoic acid 8 increases expression ISO Vitamin A results in increased expression of STRA8 mRNA CTD PMID:16461896 NCBI chr 4:63,601,443...63,624,777
Ensembl chr 4:63,601,604...63,624,771
JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression ISO Vitamin A results in decreased expression of SYCP3 mRNA CTD PMID:30944279 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511
JBrowse link
G Tfrc transferrin receptor decreases expression
increases expression
ISO
EXP
Vitamin A results in decreased expression of TFRC protein
Vitamin A deficiency results in increased expression of TFRC mRNA; Vitamin A deficiency results in increased expression of TFRC protein
CTD PMID:16960172 PMID:22154532 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP Vitamin A deficiency results in increased expression of TGFA mRNA CTD PMID:7519440 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression ISO Vitamin A results in increased expression of TGFB3 mRNA CTD PMID:17225872 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression ISO Vitamin A results in decreased expression of TGFBR1 mRNA CTD PMID:17225872 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Vitamin A results in increased expression of TGFBR2 mRNA CTD PMID:17225872 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tgm2 transglutaminase 2 increases expression
affects expression
ISO
EXP
Vitamin A results in increased expression of TGM2 mRNA
Vitamin A affects the expression of TGM2 mRNA
CTD PMID:14529804 PMID:17034753 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO Vitamin A results in increased expression of TLR2 mRNA CTD PMID:17033190 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO Vitamin A results in increased expression of TLR4 mRNA CTD PMID:17033190 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmem245 transmembrane protein 245 decreases expression EXP Vitamin A deficiency results in decreased expression of TMEM245 mRNA CTD PMID:12163651 NCBI chr 5:71,570,952...71,647,915
Ensembl chr 5:71,514,858...71,647,763
JBrowse link
G Tnf tumor necrosis factor affects secretion
increases expression
EXP Vitamin A affects the secretion of TNF protein
Vitamin A results in increased expression of TNF mRNA; Vitamin A results in increased expression of TNF protein
CTD PMID:15135310 PMID:17289162 PMID:22274401 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tob1 transducer of ErbB-2.1 multiple interactions
increases expression
ISO CRABP2 protein promotes the reaction [Vitamin A results in increased expression of TOB1 mRNA] CTD PMID:17234770 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Vitamin A results in increased expression of TPI1 mRNA alternative form CTD PMID:8793052 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Ttr transthyretin multiple interactions ISO Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]; Vitamin A promotes the reaction [RBP4 protein binds to TTR protein] CTD PMID:21591606 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Ubc ubiquitin C increases expression EXP Vitamin A deficiency results in increased expression of UBC mRNA CTD PMID:12163651 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP [Valproic Acid co-treated with Vitamin A deficiency] affects the expression of UCHL1 protein CTD PMID:32526256 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP LEP gene mutant form promotes the reaction [Vitamin A results in increased expression of UCP1 mRNA] CTD PMID:16493122 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP Vitamin A inhibits the reaction [Triiodothyronine results in decreased expression of UGT1A1 mRNA] CTD PMID:11299074 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
decreases expression
EXP Vitamin A inhibits the reaction [Triiodothyronine results in increased expression of UGT1A6 mRNA]
Vitamin A deficiency results in decreased expression of UGT1A6 mRNA
CTD PMID:11299074 PMID:12163651 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
all-trans-retinyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP retinol palmitate results in increased activity of CAT protein CTD PMID:20679000 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Il10 interleukin 10 multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:17377406 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1RN protein] CTD PMID:17377406 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Lipe lipase E, hormone sensitive type increases hydrolysis
multiple interactions
ISO LIPE protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]
CTD PMID:16741517 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein]; retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein]
retinol palmitate results in increased expression of MMP9 mRNA
CTD PMID:17164434 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Plin3 perilipin 3 multiple interactions ISO PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]; PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate] CTD PMID:16741517 NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 increases hydrolysis
multiple interactions
ISO PNPLA4 protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate]
CTD PMID:16741517 NCBI chr  X:42,313,554...42,318,451
Ensembl chr  X:42,305,373...42,318,552
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions EXP retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP retinol palmitate results in increased expression of SCARB1 mRNA CTD PMID:17299104 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
allyl alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO allyl alcohol results in increased expression of ABCC1 mRNA; allyl alcohol results in increased expression of ABCC1 protein CTD PMID:19371622 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO allyl alcohol results in increased expression of ABCC2 protein CTD PMID:19371622 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO allyl alcohol results in increased expression of ABCC3 mRNA CTD PMID:19371622 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO allyl alcohol results in increased expression of ABCC4 mRNA; allyl alcohol results in increased expression of ABCC4 protein CTD PMID:19371622 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO allyl alcohol results in increased expression of ABCC5 mRNA; allyl alcohol results in increased expression of ABCC5 protein CTD PMID:19371622 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO allyl alcohol results in decreased expression of ABCC6 mRNA CTD PMID:19371622 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide increases oxidation
multiple interactions
ISO ADH1 protein results in increased oxidation of allyl alcohol
[ADH1 protein results in increased oxidation of allyl alcohol] which results in increased abundance of Acetone
CTD PMID:11981770 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Afp alpha-fetoprotein increases expression ISO
EXP
allyl alcohol results in increased expression of AFP protein CTD PMID:61145 PMID:70250 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP allyl alcohol results in increased expression of BCAT1 mRNA CTD PMID:23558518 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO allyl alcohol results in increased expression of CCL2 mRNA CTD PMID:21907259 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP allyl alcohol results in increased expression of CYP2B1 protein CTD PMID:10445401 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO allyl alcohol results in increased expression of CYP2E1 protein CTD PMID:11515535 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression EXP allyl alcohol results in decreased expression of CYP3A2 protein CTD PMID:10445401 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases secretion
increases activity
ISO
EXP
diisopropyl 1,3-dithiol-2-ylidenemalonate inhibits the reaction [allyl alcohol results in increased activity of GPT protein]
allyl alcohol results in increased secretion of GPT protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]; Caffeine promotes the reaction [allyl alcohol results in increased activity of GPT protein]; chelerythrine inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]; fomepizole inhibits the reaction [Caffeine promotes the reaction [allyl alcohol results in increased activity of GPT protein]]; Genistein inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]; rottlerin inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]
CTD PMID:3795300 PMID:11394713 PMID:12755590 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO allyl alcohol results in increased expression of HAVCR1 mRNA CTD PMID:21907259 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO allyl alcohol results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Il1b interleukin 1 beta increases expression EXP allyl alcohol results in increased expression of IL1B mRNA CTD PMID:15135310 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression EXP allyl alcohol results in increased expression of IL6 mRNA CTD PMID:15135310 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP allyl alcohol results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G Mir122 microRNA 122 increases expression EXP allyl alcohol results in increased expression of MIR122 mRNA CTD PMID:23143187 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP allyl alcohol results in increased expression of NOS2 mRNA CTD PMID:15135310 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer multiple interactions EXP allyl alcohol results in increased expression of and results in increased secretion of PCOLCE protein CTD PMID:26396155 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
JBrowse link
G Prkcd protein kinase C, delta affects localization
increases phosphorylation
multiple interactions
EXP allyl alcohol affects the localization of PRKCD protein
allyl alcohol results in increased phosphorylation of PRKCD protein
fomepizole inhibits the reaction [allyl alcohol affects the localization of PRKCD protein]
CTD PMID:12755590 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP allyl alcohol results in increased expression of PTGS2 mRNA
allyl alcohol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
CTD PMID:11446826 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
EXP 15-deoxyprostaglandin J2 inhibits the reaction [allyl alcohol affects the localization of RELA protein] CTD PMID:14657518 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO allyl alcohol results in decreased expression of SLC10A1 mRNA; allyl alcohol results in decreased expression of SLC10A1 protein CTD PMID:19371622 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression ISO allyl alcohol results in increased expression of SLCO1A4 protein CTD PMID:19371622 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression ISO allyl alcohol results in decreased expression of SLCO1B2 mRNA; allyl alcohol results in decreased expression of SLCO1B2 protein CTD PMID:19371622 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP allyl alcohol results in increased expression of SPP1 mRNA CTD PMID:23558518 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO allyl alcohol results in increased expression of SRXN1 protein CTD PMID:27358234 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
EXP allyl alcohol results in increased expression of TGFB1 mRNA
Tamoxifen inhibits the reaction [allyl alcohol results in increased expression of TGFB1 mRNA]
CTD PMID:11063159 PMID:18564211 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions
increases expression
EXP Tamoxifen inhibits the reaction [allyl alcohol results in increased expression of TGFBR1 mRNA] CTD PMID:18564211 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP allyl alcohol results in increased expression of TIMP1 mRNA CTD PMID:23558518 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor increases expression EXP allyl alcohol results in increased expression of TNF mRNA CTD PMID:15135310 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vnn1 vanin 1 increases expression ISO allyl alcohol results in increased expression of VNN1 mRNA CTD PMID:21907259 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
beraprost term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP3 protein] CTD PMID:28887131 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO (2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline) inhibits the reaction [beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]]; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein] CTD PMID:28887131 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HBEGF mRNA] CTD PMID:28887131 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO beraprost results in decreased expression of HGF mRNA CTD PMID:28887131 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP beraprost inhibits the reaction [Hydrochloric Acid results in increased expression of HMOX1 protein] CTD PMID:18617559 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MPO protein] CTD PMID:28887131 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFE2L2 mRNA] CTD PMID:28887131 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ptgir prostaglandin I2 receptor multiple interactions ISO beraprost binds to and results in increased activity of PTGIR protein; Endocannabinoids inhibits the reaction [beraprost binds to and results in increased activity of PTGIR protein] CTD PMID:30102254 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein] CTD PMID:28887131 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA] CTD PMID:28887131 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
carbocyclic thromboxane A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression ISO thromboxane A2, carbocyclic results in decreased expression of TNFRSF11B mRNA CTD PMID:18264100 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf11 TNF superfamily member 11 increases expression ISO thromboxane A2, carbocyclic results in increased expression of TNFSF11 mRNA CTD PMID:18264100 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
fostriecin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO fostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]] CTD PMID:24954032 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Casp3 caspase 3 multiple interactions ISO fostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]] CTD PMID:24954032 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO fostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of FOXO3 protein]] CTD PMID:24954032 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO fostriecin promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]] CTD PMID:24954032 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
ganoderol B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO ganoderol B binds to and results in decreased activity of AR protein; ganoderol B inhibits the reaction [Dihydrotestosterone binds to AR protein] CTD PMID:17499997 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO ganoderol B results in decreased expression of KLK3 mRNA CTD PMID:17499997 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity EXP ganoderol B results in decreased activity of SRD5A1 protein CTD PMID:17499997 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
geraniol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] CTD PMID:31005848 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO geraniol results in decreased expression of ACACA mRNA CTD PMID:26141755 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP geraniol inhibits the reaction [Acrylamide results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:24752916 PMID:25199698 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACTA2 mRNA] CTD PMID:26695085 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actl6a actin-like 6A decreases expression ISO geraniol results in decreased expression of ACTL6A mRNA CTD PMID:27683099 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401
JBrowse link
G Acvr1 activin A receptor type 1 increases expression ISO geraniol results in increased expression of ACVR1 mRNA CTD PMID:27683099 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP geraniol inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein] CTD PMID:25679220 PMID:28178614 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Aff4 ALF transcription elongation factor 4 increases expression ISO geraniol results in increased expression of AFF4 mRNA CTD PMID:27683099 NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP geraniol inhibits the reaction [Fructose results in increased expression of AGER protein] CTD PMID:25679220 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ahctf1 AT hook containing transcription factor 1 decreases expression ISO geraniol results in decreased expression of AHCTF1 mRNA CTD PMID:27683099 NCBI chr13:91,481,936...91,536,391
Ensembl chr13:91,481,936...91,536,391
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO geraniol results in increased expression of AKR1C1 mRNA CTD PMID:30806763 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 increases expression ISO geraniol results in increased expression of AP5Z1 mRNA CTD PMID:27683099 NCBI chr12:12,093,834...12,109,043
Ensembl chr12:12,093,834...12,108,511
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 increases expression ISO geraniol results in increased expression of APBB2 mRNA CTD PMID:27683099 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 decreases expression ISO geraniol results in decreased expression of APPL1 mRNA CTD PMID:27683099 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO geraniol results in increased expression of ATF3 mRNA CTD PMID:27683099 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of ATF4 protein] CTD PMID:30141137 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions
ISO geraniol results in increased expression of ATF6 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of ATF6 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG12 protein] CTD PMID:30141137 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG5 protein] CTD PMID:30141137 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG7 protein] CTD PMID:30141137 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO geraniol results in increased expression of BAK1 protein CTD PMID:12530055 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of BAX protein]
geraniol inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]
geraniol results in increased expression of BAX mRNA; geraniol results in increased expression of BAX protein
CTD PMID:21371438 PMID:22760862 PMID:24768735 PMID:29050341 PMID:29745075 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B decreases expression ISO geraniol results in decreased expression of BAZ1B mRNA CTD PMID:27683099 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression ISO geraniol results in increased expression of BAZ2B mRNA CTD PMID:27683099 NCBI chr 3:44,384,282...44,681,619
Ensembl chr 3:44,385,474...44,592,908
JBrowse link
G Bbx BBX high mobility group box domain containing increases expression ISO geraniol results in increased expression of BBX mRNA CTD PMID:27683099 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
JBrowse link
G Bcl11a BCL11 transcription factor A decreases expression ISO geraniol results in decreased expression of BCL11A mRNA CTD PMID:27683099 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
ISO
EXP
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of BCL2 protein]
geraniol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]
geraniol results in decreased expression of BCL2 mRNA; geraniol results in decreased expression of BCL2 protein
geraniol results in increased expression of BCL2 protein
CTD PMID:21371438 PMID:21445532 PMID:22760862 PMID:24768735 PMID:29050341 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of BCL2L1 protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA] CTD PMID:26695085 PMID:35608392 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression ISO geraniol results in decreased expression of BCL2L2 protein CTD PMID:21371438 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO geraniol results in increased expression of BCL6 mRNA CTD PMID:27683099 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO geraniol results in decreased expression of BCLAF1 mRNA CTD PMID:27683099 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein] CTD PMID:23943375 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO geraniol results in decreased expression of BIRC5 mRNA CTD PMID:27683099 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO geraniol results in increased expression of BMAL1 mRNA CTD PMID:27683099 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO geraniol results in increased expression of BMP6 mRNA CTD PMID:27683099 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO geraniol results in increased expression of BNIP3 protein CTD PMID:21371438 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO geraniol results in decreased expression of BRCA1 mRNA CTD PMID:27683099 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO geraniol results in decreased expression of BRCA2 mRNA CTD PMID:27683099 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Btf3 basic transcription factor 3 decreases expression ISO geraniol results in decreased expression of BTF3 mRNA CTD PMID:27683099 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO geraniol results in decreased expression of BUB1 mRNA CTD PMID:27683099 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO geraniol results in decreased expression of BUB1B mRNA CTD PMID:27683099 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP3 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]
geraniol results in increased activity of CASP3 protein
geraniol results in increased expression of CASP3 mRNA; geraniol results in increased expression of CASP3 protein
geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CASP3 protein]
geraniol results in increased expression of CASP3 protein modified form
CTD PMID:21371438 PMID:21907755 PMID:22509279 PMID:24875281 PMID:26154255 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
EXP
ISO
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA]
geraniol results in increased expression of CASP8 mRNA; geraniol results in increased expression of CASP8 protein
CTD PMID:21907755 PMID:30506710 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP9 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP9 protein]
geraniol results in increased expression of CASP9 mRNA; geraniol results in increased expression of CASP9 protein
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein]
CTD PMID:21907755 PMID:22509279 PMID:24768735 PMID:26364502 PMID:26695085 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
increases activity
ISO
EXP
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]
geraniol results in decreased activity of CAT protein
geraniol results in increased activity of CAT protein
geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of CAT protein]; geraniol inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of CAT mRNA]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
CTD PMID:21907755 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbfa2t2 CBFA2/RUNX1 partner transcriptional co-repressor 2 increases expression ISO geraniol results in increased expression of CBFA2T2 mRNA CTD PMID:27683099 NCBI chr 3:142,936,945...143,043,205
Ensembl chr 3:142,936,985...143,043,197
JBrowse link
G Cbfb core-binding factor subunit beta decreases expression ISO geraniol results in decreased expression of CBFB mRNA CTD PMID:27683099 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion ISO geraniol results in increased secretion of CCL4 protein CTD PMID:30806763 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO geraniol results in decreased expression of CCNA2 mRNA; geraniol results in decreased expression of CCNA2 protein CTD PMID:17138864 PMID:27683099 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO geraniol results in decreased expression of CCNB1 protein CTD PMID:17138864 PMID:21371438 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO geraniol results in decreased expression of CCND1 protein CTD PMID:15450939 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd86 CD86 molecule increases expression ISO geraniol results in increased expression of CD86 protein CTD PMID:30806763 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO geraniol results in decreased expression of CDC20 mRNA CTD PMID:27683099 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO geraniol results in decreased expression of CDC25A mRNA CTD PMID:27683099 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO geraniol results in decreased expression of CDC25C mRNA CTD PMID:27683099 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO geraniol results in decreased expression of CDC45 mRNA CTD PMID:27683099 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdc7 cell division cycle 7 decreases expression ISO geraniol results in decreased expression of CDC7 mRNA CTD PMID:27683099 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] CTD PMID:28428697 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO geraniol results in decreased expression of CDK1 protein CTD PMID:21371438 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
ISO geraniol results in decreased expression of CDK2 mRNA; geraniol results in decreased expression of CDK2 protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:15450939 PMID:17138864 PMID:27683099 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO geraniol results in decreased expression of CDK4 protein CTD PMID:15450939 PMID:21371438 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
increases response to substance
ISO geraniol results in increased expression of CDKN1A protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
CDKN1A protein results in increased susceptibility to geraniol
CTD PMID:17138864 PMID:21371438 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
increases response to substance
ISO geraniol results in increased expression of CDKN1B protein
geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CDKN1B protein results in increased susceptibility to geraniol
CTD PMID:17138864 PMID:21371438 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO geraniol results in decreased expression of CDKN2C mRNA CTD PMID:27683099 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO geraniol results in decreased expression of CDKN3 mRNA CTD PMID:27683099 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 decreases expression ISO geraniol results in decreased expression of CDT1 mRNA CTD PMID:27683099 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO geraniol results in increased expression of CEBPB mRNA CTD PMID:27683099 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO geraniol results in increased expression of CEBPG mRNA CTD PMID:27683099 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cenpe centromere protein E decreases expression ISO geraniol results in decreased expression of CENPE mRNA CTD PMID:27683099 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenpf centromere protein F decreases expression ISO geraniol results in decreased expression of CENPF mRNA CTD PMID:27683099 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO geraniol results in decreased expression of CHEK1 mRNA CTD PMID:27683099 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Cit citron rho-interacting serine/threonine kinase decreases expression ISO geraniol results in decreased expression of CIT mRNA CTD PMID:27683099 NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
JBrowse link
G Ckm creatine kinase, M-type multiple interactions EXP geraniol inhibits the reaction [Doxorubicin results in increased activity of CKM protein] CTD PMID:34343525 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression ISO geraniol results in decreased expression of CNBP mRNA CTD PMID:27683099 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 multiple interactions ISO CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr  X:149,696,999...149,715,051
Ensembl chr  X:149,696,997...149,715,051
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA] CTD PMID:26695085 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA] CTD PMID:24768735 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO geraniol results in increased expression of CREB3 mRNA CTD PMID:27683099 NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 increases expression ISO geraniol results in increased expression of CREB3L2 mRNA CTD PMID:27683099 NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
JBrowse link
G Crp C-reactive protein multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of CRP protein] CTD PMID:35608392 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein] CTD PMID:26165751 PMID:28428697 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsd cathepsin D multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CTSD protein] CTD PMID:23499697 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CYB5A protein] CTD PMID:23499697 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO geraniol inhibits the reaction [Dietary Fats results in increased expression of CYBB protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of CYBB protein]
CTD PMID:27107694 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein] CTD PMID:24768735 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases metabolic processing
ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite CTD PMID:18824010 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol CTD PMID:18824010 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases metabolic processing
ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP2B6 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; geraniol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 PMID:18824010 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein]
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol
CTD PMID:18824010 PMID:26695085 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing
multiple interactions
ISO CYP3A5 protein results in increased metabolism of geraniol
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite
CTD PMID:18824010 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit decreases expression ISO geraniol results in decreased expression of DBF4 mRNA CTD PMID:27683099 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO geraniol results in increased expression of DDIT3 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of DDIT3 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dek DEK proto-oncogene decreases expression ISO geraniol results in decreased expression of DEK mRNA CTD PMID:27683099 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Dmtf1 cyclin D binding myb-like transcription factor 1 increases expression ISO geraniol results in increased expression of DMTF1 mRNA CTD PMID:27683099 NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 increases expression ISO geraniol results in increased expression of DNAJC1 mRNA CTD PMID:27683099 NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO geraniol results in decreased expression of DR1 mRNA CTD PMID:27683099 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression ISO geraniol results in decreased expression of DTYMK mRNA CTD PMID:27683099 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO geraniol results in decreased expression of E2F1 mRNA CTD PMID:27683099 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO geraniol results in decreased expression of E2F8 mRNA; geraniol results in decreased expression of E2F8 protein CTD PMID:27683099 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Ehf ets homologous factor decreases expression ISO geraniol results in decreased expression of EHF mRNA CTD PMID:27683099 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of EIF2AK3 protein] CTD PMID:30141137 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of EIF2S1 protein] CTD PMID:30141137 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Elavl2 ELAV like RNA binding protein 2 decreases expression ISO geraniol results in decreased expression of ELAVL2 mRNA CTD PMID:27683099 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097
JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO geraniol results in increased expression of ELF1 mRNA CTD PMID:27683099 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
JBrowse link
G Elk4 ETS transcription factor ELK4 increases expression ISO geraniol results in increased expression of ELK4 mRNA CTD PMID:27683099 NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035
JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 increases expression ISO geraniol results in increased expression of ERC1 mRNA CTD PMID:27683099 NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein] CTD PMID:30141137 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression ISO geraniol results in decreased expression of ESPL1 mRNA CTD PMID:27683099 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO geraniol binds to ESR1 protein
geraniol inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:12495555 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions
ISO geraniol binds to ESR2 protein
geraniol inhibits the reaction [Estradiol binds to ESR2 protein]
CTD PMID:12495555 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO geraniol results in increased expression of ETS2 mRNA CTD PMID:27683099 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Etv1 ETS variant transcription factor 1 decreases expression ISO geraniol results in decreased expression of ETV1 mRNA CTD PMID:27683099 NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 decreases expression ISO geraniol results in decreased expression of EWSR1 mRNA CTD PMID:27683099 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO geraniol results in decreased expression of EZH2 mRNA CTD PMID:27683099 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO geraniol results in increased expression of FABP4 mRNA CTD PMID:30806763 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions
decreases activity
ISO [geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid; [geraniol results in decreased activity of FADS1 protein] which results in decreased metabolism of 8,11,14-Eicosatrienoic Acid CTD PMID:16462894 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fancg FA complementation group G decreases expression ISO geraniol results in decreased expression of FANCG mRNA CTD PMID:27683099 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
JBrowse link
G Fasn fatty acid synthase multiple interactions EXP geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FASN mRNA] CTD PMID:26695085 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO geraniol results in decreased expression of FBXO5 mRNA CTD PMID:27683099 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of FOS mRNA CTD PMID:27683099 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit decreases expression ISO geraniol results in decreased expression of FOSL1 mRNA CTD PMID:27683099 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of FOSL2 mRNA CTD PMID:27683099 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO geraniol results in decreased expression of FOXA2 mRNA CTD PMID:27683099 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxj3 forkhead box J3 increases expression ISO geraniol results in increased expression of FOXJ3 mRNA CTD PMID:27683099 NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO geraniol results in decreased expression of FOXM1 mRNA CTD PMID:27683099 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo4 forkhead box O4 increases expression ISO geraniol results in increased expression of FOXO4 mRNA CTD PMID:27683099 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Fst follistatin increases expression ISO geraniol results in increased expression of FST mRNA CTD PMID:27683099 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO geraniol results in decreased expression of FUBP1 mRNA CTD PMID:27683099 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO
EXP
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein]
geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]
CTD PMID:23399806 PMID:28330423 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gatad1 GATA zinc finger domain containing 1 increases expression ISO geraniol results in increased expression of GATAD1 mRNA CTD PMID:27683099 NCBI chr 4:30,507,530...30,519,107
Ensembl chr 4:30,507,538...30,519,107
JBrowse link
G Gbx2 gastrulation brain homeobox 2 decreases expression ISO geraniol results in decreased expression of GBX2 mRNA CTD PMID:27683099 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
JBrowse link
G Gcg glucagon multiple interactions
increases secretion
ISO 9-(tetrahydro-2-furyl)-adenine inhibits the reaction [geraniol results in increased secretion of GCG protein]; CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF protein] CTD PMID:23943375 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gmnn geminin, DNA replication inhibitor decreases expression ISO geraniol results in decreased expression of GMNN mRNA CTD PMID:27683099 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
G Gna15 G protein subunit alpha 15 increases response to substance
multiple interactions
ISO GNA15 protein results in increased susceptibility to geraniol
[GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein
CTD PMID:15598656 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gnal G protein subunit alpha L increases response to substance
multiple interactions
ISO GNAL protein results in increased susceptibility to geraniol
[GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]
CTD PMID:15598656 PMID:29070885 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP geraniol inhibits the reaction [Doxorubicin results in increased activity of GOT1 protein] CTD PMID:34343525 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP geraniol inhibits the reaction [Doxorubicin results in increased activity of GPT protein] CTD PMID:34343525 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA] CTD PMID:22509279 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] CTD PMID:26165751 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]
geraniol results in decreased activity of GSR protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]
CTD PMID:22509279 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein] CTD PMID:27046949 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gtf2b general transcription factor IIB increases expression ISO geraniol results in increased expression of GTF2B mRNA CTD PMID:27683099 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 increases expression ISO geraniol results in increased expression of GTF2H1 mRNA CTD PMID:27683099 NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455
JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 increases expression ISO geraniol results in increased expression of GTF2IRD1 mRNA CTD PMID:27683099 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
JBrowse link
G Gtf3a general transcription factor III A decreases expression ISO geraniol results in decreased expression of GTF3A mRNA CTD PMID:27683099 NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690
JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 increases expression ISO geraniol results in increased expression of GTF3C1 mRNA CTD PMID:27683099 NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 protein] CTD PMID:21907755 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions EXP geraniol inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]] CTD PMID:25679220 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO geraniol results in increased expression of HBP1 mRNA CTD PMID:27683099 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hivep1 HIVEP zinc finger 1 increases expression ISO geraniol results in increased expression of HIVEP1 mRNA CTD PMID:27683099 NCBI chr17:22,585,016...22,714,517
Ensembl chr17:22,585,016...22,711,956
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO geraniol results in decreased expression of HLF mRNA CTD PMID:27683099 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
JBrowse link
G Hmbox1 homeobox containing 1 increases expression ISO geraniol results in increased expression of HMBOX1 mRNA CTD PMID:27683099 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323
JBrowse link
G Hmg20b high mobility group 20 B decreases expression ISO geraniol results in decreased expression of HMG20B mRNA CTD PMID:27683099 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO geraniol results in decreased expression of HMGB2 mRNA CTD PMID:27683099 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgb3 high mobility group box 3 decreases expression ISO geraniol results in decreased expression of HMGB3 mRNA CTD PMID:27683099 NCBI chr  X:149,296,303...149,301,290
Ensembl chr  X:149,296,375...149,301,292
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
decreases expression
affects expression
decreases activity
ISO geraniol results in increased expression of HMGCR mRNA
geraniol results in decreased expression of HMGCR protein
geraniol affects the expression of HMGCR mRNA
geraniol results in decreased activity of HMGCR protein
CTD PMID:12477733 PMID:15450939 PMID:16462894 PMID:23668785 PMID:24875281 More... NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgxb3 HMG-box containing 3 increases expression ISO geraniol results in increased expression of HMGXB3 mRNA CTD PMID:27683099 NCBI chr18:54,590,558...54,638,050
Ensembl chr18:54,590,560...54,638,155
JBrowse link
G Hmgxb4 HMG-box containing 4 decreases expression ISO geraniol results in decreased expression of HMGXB4 mRNA CTD PMID:27683099 NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
geraniol results in increased expression of HMOX1 mRNA
geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 protein]
geraniol results in increased expression of HMOX1 protein
CTD PMID:20713136 PMID:28334550 PMID:30806763 PMID:34343525 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B decreases expression ISO geraniol results in decreased expression of HNRNPAB mRNA CTD PMID:27683099 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
JBrowse link
G Hoxa5 homeo box A5 increases expression ISO geraniol results in increased expression of HOXA5 mRNA CTD PMID:27683099 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234
JBrowse link
G Hoxb13 homeo box B13 decreases expression ISO geraniol results in decreased expression of HOXB13 mRNA CTD PMID:27683099 NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777
JBrowse link
G Hoxc6 homeo box C6 increases expression ISO geraniol results in increased expression of HOXC6 mRNA CTD PMID:27683099 NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein CTD PMID:22760862 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO geraniol results in decreased expression of HSPA2 mRNA CTD PMID:27683099 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases activity ISO geraniol results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO
EXP
geraniol inhibits the reaction [Dietary Fats results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]
CTD PMID:26165751 PMID:27107694 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO geraniol results in increased expression of ID1 mRNA CTD PMID:27683099 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO geraniol results in increased expression of ID3 mRNA CTD PMID:27683099 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ifng interferon gamma multiple interactions ISO geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein] CTD PMID:26973525 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions
ISO geraniol results in increased expression of IL10 protein
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL10 protein]
CTD PMID:24934659 PMID:26973525 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il16 interleukin 16 increases secretion ISO geraniol results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il17a interleukin 17A multiple interactions ISO geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein] CTD PMID:26973525 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 multiple interactions ISO
EXP
geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]
geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein]
CTD PMID:21430599 PMID:34343525 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO geraniol results in increased expression of IL1A protein CTD PMID:19878710 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of IL1B protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; geraniol inhibits the reaction [ovalbumin-alum results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]
geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]
CTD PMID:20304105 PMID:21282739 PMID:21430599 PMID:23399806 PMID:25679220 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO geraniol results in increased expression of IL1R2 mRNA CTD PMID:30806763 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; geraniol inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL6 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
geraniol results in increased expression of IL6 mRNA
CTD PMID:23399806 PMID:26190278 PMID:26695085 PMID:26973525 PMID:27107694 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO geraniol results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Ilf2 interleukin enhancer binding factor 2 decreases expression ISO geraniol results in decreased expression of ILF2 mRNA CTD PMID:27683099 NCBI chr 2:175,952,174...175,971,191
Ensembl chr 2:175,952,186...175,971,337
JBrowse link
G Ins1 insulin 1 increases secretion
multiple interactions
ISO
EXP
geraniol results in increased secretion of INS1 protein
geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]
CTD PMID:28330423 PMID:29070885 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO geraniol results in increased expression of IRF1 mRNA CTD PMID:27683099 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf6 interferon regulatory factor 6 increases expression ISO geraniol results in increased expression of IRF6 mRNA CTD PMID:27683099 NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO geraniol results in increased expression of IRF7 mRNA CTD PMID:27683099 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO geraniol results in increased expression of IRF9 mRNA CTD PMID:27683099 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 increases expression ISO geraniol results in increased expression of JARID2 mRNA CTD PMID:27683099 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
JBrowse link
G Jmjd1c jumonji domain containing 1C increases expression ISO geraniol results in increased expression of JMJD1C mRNA CTD PMID:27683099 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of JUN mRNA CTD PMID:27683099 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of JUNB mRNA CTD PMID:27683099 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of JUND mRNA CTD PMID:27683099 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO geraniol results in decreased expression of KDR protein CTD PMID:26154255 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases expression ISO geraniol results in decreased expression of KHDRBS1 mRNA CTD PMID:27683099 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO geraniol results in decreased expression of KIF11 mRNA CTD PMID:27683099 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif15 kinesin family member 15 decreases expression ISO geraniol results in decreased expression of KIF15 mRNA CTD PMID:27683099 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif22 kinesin family member 22 decreases expression ISO geraniol results in decreased expression of KIF22 mRNA CTD PMID:27683099 NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO geraniol results in decreased expression of KIF23 mRNA CTD PMID:27683099 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kif2c kinesin family member 2C decreases expression ISO geraniol results in decreased expression of KIF2C mRNA CTD PMID:27683099 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Klf11 KLF transcription factor 11 increases expression ISO geraniol results in increased expression of KLF11 mRNA CTD PMID:27683099 NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
JBrowse link
G Klf13 KLF transcription factor 13 increases expression ISO geraniol results in increased expression of KLF13 mRNA CTD PMID:27683099 NCBI chr 1:117,505,857...117,536,626
Ensembl chr 1:117,503,602...117,551,227
JBrowse link
G Klf3 KLF transcription factor 3 increases expression ISO geraniol results in increased expression of KLF3 mRNA CTD PMID:27683099 NCBI chr14:43,474,767...43,505,801
Ensembl chr14:43,474,767...43,497,209
JBrowse link
G Klf4 KLF transcription factor 4 increases expression ISO geraniol results in increased expression of KLF4 mRNA CTD PMID:27683099 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf5 KLF transcription factor 5 increases expression ISO geraniol results in increased expression of KLF5 mRNA CTD PMID:27683099 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf6 KLF transcription factor 6 increases expression ISO geraniol results in increased expression of KLF6 mRNA CTD PMID:27683099 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klf7 KLF transcription factor 7 increases expression ISO geraniol results in increased expression of KLF7 mRNA CTD PMID:27683099 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Kntc1 kinetochore associated 1 decreases expression ISO geraniol results in decreased expression of KNTC1 mRNA CTD PMID:27683099 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA] CTD PMID:28428697 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO geraniol results in increased expression of LDLR mRNA CTD PMID:26141755 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression ISO geraniol results in decreased expression of LIF protein CTD PMID:19878710 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lztfl1 leucine zipper transcription factor-like 1 increases expression ISO geraniol results in increased expression of LZTFL1 mRNA CTD PMID:27683099 NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:123,344,925...123,360,192
JBrowse link
G Lztr1 leucine zipper like post translational regulator 1 increases expression ISO geraniol results in increased expression of LZTR1 mRNA CTD PMID:27683099 NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO geraniol results in decreased expression of MAD2L1 mRNA CTD PMID:27683099 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO geraniol results in increased expression of MAFF mRNA CTD PMID:27683099 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO geraniol results in increased expression of MAFG mRNA CTD PMID:27683099 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Maob monoamine oxidase B multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of MAOB protein] CTD PMID:24103762 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA] CTD PMID:28428697 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein]
geraniol results in decreased phosphorylation of MAPK1 protein
CTD PMID:12388655 PMID:22760862 PMID:26154255 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO
EXP
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein]
geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK3 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
geraniol results in decreased phosphorylation of MAPK3 protein
CTD PMID:12388655 PMID:22760862 PMID:26154255 PMID:35608392 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:35608392 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO geraniol results in decreased expression of MCM2 mRNA CTD PMID:27683099 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mef2a myocyte enhancer factor 2a increases expression ISO geraniol results in increased expression of MEF2A mRNA CTD PMID:27683099 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Men1 menin 1 increases expression ISO geraniol results in increased expression of MEN1 mRNA CTD PMID:27683099 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO geraniol results in decreased expression of MKI67 mRNA
geraniol results in decreased expression of MKI67 protein
CTD PMID:26154255 PMID:27683099 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP2 mRNA] CTD PMID:35608392 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO geraniol results in increased expression of MMP3 mRNA CTD PMID:30806763 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA] CTD PMID:35608392 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnt MAX network transcriptional repressor increases expression ISO geraniol results in increased expression of MNT mRNA CTD PMID:27683099 NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO
EXP
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]
geraniol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MPO protein]; geraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; geraniol inhibits the reaction [Ethanol results in increased expression of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]
CTD PMID:24337826 PMID:26165751 PMID:26190278 PMID:30550845 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases activity
multiple interactions
ISO geraniol results in decreased activity of MTOR protein
geraniol inhibits the reaction [Rotenone results in increased phosphorylation of MTOR protein]
CTD PMID:22200837 PMID:30141137 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mvk mevalonate kinase multiple interactions ISO geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] CTD PMID:20304105 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO geraniol results in increased expression of MXD1 mRNA CTD PMID:27683099 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Mxd4 Max dimerization protein 4 increases expression ISO geraniol results in increased expression of MXD4 mRNA CTD PMID:27683099 NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO geraniol results in increased expression of MXI1 mRNA CTD PMID:27683099 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO geraniol results in decreased expression of MYB mRNA CTD PMID:27683099 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Mybl1 MYB proto-oncogene like 1 decreases expression ISO geraniol results in decreased expression of MYBL1 mRNA CTD PMID:27683099 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO geraniol results in decreased expression of MYBL2 mRNA CTD PMID:27683099 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myo6 myosin VI increases expression ISO geraniol results in increased expression of MYO6 mRNA CTD PMID:27683099 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
JBrowse link
G Nasp nuclear autoantigenic sperm protein decreases expression ISO geraniol results in decreased expression of NASP mRNA CTD PMID:27683099 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO geraniol results in decreased expression of NCAPH mRNA CTD PMID:27683099 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 increases expression ISO geraniol results in increased expression of NCOR1 mRNA CTD PMID:27683099 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ndp norrin cystine knot growth factor NDP decreases expression ISO geraniol results in decreased expression of NDP mRNA CTD PMID:27683099 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression ISO geraniol results in decreased expression of NEK2 mRNA CTD PMID:27683099 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO geraniol results in increased expression of NFAT5 mRNA CTD PMID:27683099 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO geraniol results in increased expression of NFE2L1 mRNA CTD PMID:27683099 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
ISO
EXP
geraniol results in increased expression of NFE2L2 mRNA
geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 protein]
geraniol results in increased expression of NFE2L2 protein
CTD PMID:27683099 PMID:28334550 PMID:34343525 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO geraniol results in increased expression of NFIL3 mRNA CTD PMID:27683099 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of NFKB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein] CTD PMID:21907755 PMID:26165751 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO
EXP
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
geraniol inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of NFKBIA protein]
CTD PMID:20506077 PMID:26190278 PMID:29050341 PMID:30550845 PMID:34343525 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfyb nuclear transcription factor Y subunit beta decreases expression ISO geraniol results in decreased expression of NFYB mRNA CTD PMID:27683099 NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of NOS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NOS2 protein]
geraniol results in decreased expression of NOS2 mRNA; geraniol results in decreased expression of NOS2 protein
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]
CTD PMID:20506077 PMID:22509279 PMID:26190278 PMID:26364502 PMID:26695085 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO geraniol inhibits the reaction [Palmitic Acid results in increased expression of NOX1 protein] CTD PMID:27107694 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Npm1 nucleophosmin 1 decreases expression ISO geraniol results in decreased expression of NPM1 mRNA CTD PMID:27683099 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in decreased activity of NQO1 protein]; geraniol inhibits the reaction [Doxorubicin results in decreased expression of NQO1 protein] CTD PMID:23499697 PMID:34343525 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO geraniol results in increased expression of NR1D1 mRNA CTD PMID:27683099 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO geraniol results in increased expression of NR1D2 mRNA CTD PMID:27683099 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO geraniol results in decreased expression of NR2F1 mRNA CTD PMID:27683099 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression ISO geraniol results in increased expression of NR3C1 mRNA CTD PMID:27683099 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO geraniol results in increased expression of NR4A2 mRNA CTD PMID:27683099 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 decreases expression ISO geraniol results in decreased expression of NSD2 mRNA CTD PMID:27683099 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO geraniol results in decreased expression of NUSAP1 mRNA CTD PMID:27683099 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
decreases activity
ISO geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]
geraniol results in decreased activity of ODC1 protein
CTD PMID:11408542 PMID:22760862 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions EXP [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein] CTD PMID:22509279 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Or1a1 olfactory receptor family 1 subfamily A member 1 multiple interactions ISO [GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; [GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:15598656 PMID:29070885 NCBI chr10:59,058,941...59,059,879
Ensembl chr10:59,052,828...59,060,676
JBrowse link
G Or1ad5 olfactory receptor family 1 subfamily AD member 5 multiple interactions ISO OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr10:35,307,662...35,308,573
Ensembl chr10:35,304,703...35,308,919
JBrowse link
G Pa2g4 proliferation-associated 2G4 decreases expression ISO geraniol results in decreased expression of PA2G4 mRNA CTD PMID:27683099 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO geraniol results in decreased expression of PBX1 mRNA CTD PMID:27683099 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression
EXP
ISO
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein]; geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]
geraniol results in decreased expression of PCNA protein
CTD PMID:21907755 PMID:26154255 PMID:26364502 PMID:27046949 PMID:28428697 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pgr progesterone receptor multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein] CTD PMID:28428697 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phb1 prohibitin 1 decreases expression
multiple interactions
ISO
EXP
geraniol results in decreased expression of PHB1 mRNA
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PHB1 protein]
CTD PMID:26695085 PMID:27683099 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phf1 PHD finger protein 1 increases expression ISO geraniol results in increased expression of PHF1 mRNA CTD PMID:27683099 NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
JBrowse link
G Phf21a PHD finger protein 21A increases expression ISO geraniol results in increased expression of PHF21A mRNA CTD PMID:27683099 NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 increases expression ISO geraniol results in increased expression of PHTF1 mRNA CTD PMID:27683099 NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA] CTD PMID:28428697 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 decreases expression ISO geraniol results in decreased expression of PKMYT1 mRNA CTD PMID:27683099 NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 increases expression ISO geraniol results in increased expression of PLAGL1 mRNA CTD PMID:27683099 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO geraniol results in decreased expression of PLK1 mRNA CTD PMID:27683099 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO geraniol results in decreased expression of POLA1 mRNA CTD PMID:27683099 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit decreases expression ISO geraniol results in decreased expression of POLE mRNA CTD PMID:27683099 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
JBrowse link
G Polr1g RNA polymerase I subunit G decreases expression ISO geraniol results in decreased expression of POLR1G mRNA CTD PMID:27683099 NCBI chr 1:79,007,490...79,010,766
Ensembl chr 1:79,007,490...79,010,766
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of POR protein] CTD PMID:23499697 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases activity
EXP
ISO
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]
geraniol results in increased activity of PPARA protein
CTD PMID:21597168 PMID:26695085 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
increases activity
multiple interactions
ISO
EXP
geraniol results in decreased expression of PPARG mRNA
geraniol results in increased activity of PPARG protein
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG protein]
geraniol inhibits the reaction [Fructose results in decreased activity of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]
CTD PMID:21597168 PMID:25679220 PMID:26165751 PMID:27683099 PMID:30550845 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO geraniol results in decreased expression of PRC1 mRNA CTD PMID:27683099 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prdm4 PR/SET domain 4 increases expression ISO geraniol results in increased expression of PRDM4 mRNA CTD PMID:27683099 NCBI chr 7:17,953,832...17,980,489
Ensembl chr 7:17,954,019...17,980,489
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 mRNA]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 protein] CTD PMID:35608392 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO geraniol results in decreased expression of PRDX3 mRNA CTD PMID:27683099 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of PRKAA1 protein] CTD PMID:30141137 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein] CTD PMID:28428697 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein]
CTD PMID:20506077 PMID:21597168 PMID:22760862 PMID:23399806 PMID:26190278 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression ISO geraniol results in decreased expression of PTTG1 mRNA CTD PMID:27683099 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Pwp1 PWP1 homolog, endonuclein decreases expression ISO geraniol results in decreased expression of PWP1 mRNA CTD PMID:27683099 NCBI chr 7:17,982,730...17,998,728
Ensembl chr 7:17,982,235...17,998,731
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO geraniol results in decreased expression of RACGAP1 mRNA CTD PMID:27683099 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO geraniol results in decreased expression of RAD51 mRNA CTD PMID:27683099 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad54b RAD54 homolog B decreases expression ISO geraniol results in decreased expression of RAD54B mRNA CTD PMID:27683099 NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616
JBrowse link
G Rad54l RAD54 like decreases expression ISO geraniol results in decreased expression of RAD54L mRNA CTD PMID:27683099 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein] CTD PMID:22760862 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO geraniol results in increased expression of RCAN1 mRNA CTD PMID:27683099 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rcor3 REST corepressor 3 increases expression ISO geraniol results in increased expression of RCOR3 mRNA CTD PMID:27683099 NCBI chr13:103,624,966...103,665,565
Ensembl chr13:103,624,971...103,665,565
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of and affects the localization of RELA protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of RELA protein]
CTD PMID:23399806 PMID:26190278 PMID:26364502 PMID:28397014 PMID:29050341 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rfx5 regulatory factor X5 increases expression ISO geraniol results in increased expression of RFX5 mRNA CTD PMID:27683099 NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717
JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase increases expression ISO geraniol results in increased expression of RNF19A mRNA CTD PMID:27683099 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 decreases expression ISO geraniol results in decreased expression of RUVBL1 mRNA CTD PMID:27683099 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 decreases expression ISO geraniol results in decreased expression of RUVBL2 mRNA CTD PMID:27683099 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
JBrowse link
G Satb1 SATB homeobox 1 increases expression ISO geraniol results in increased expression of SATB1 mRNA CTD PMID:27683099 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
JBrowse link
G Serpinb3 serpin family B member 3 increases expression ISO geraniol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Sim2 SIM bHLH transcription factor 2 increases expression ISO geraniol results in increased expression of SIM2 mRNA CTD PMID:27683099 NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO geraniol results in increased expression of SIRT1 mRNA CTD PMID:27683099 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO geraniol results in decreased expression of SKP2 mRNA CTD PMID:27683099 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC18A2 protein] CTD PMID:23943375 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc2a4rg SLC2A4 regulator decreases expression ISO geraniol results in decreased expression of SLC2A4RG mRNA CTD PMID:27683099 NCBI chr 3:168,493,975...168,497,616 JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein] CTD PMID:23943375 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Smad3 SMAD family member 3 decreases expression ISO geraniol results in decreased expression of SMAD3 mRNA CTD PMID:27683099 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad6 SMAD family member 6 decreases expression ISO geraniol results in decreased expression of SMAD6 mRNA CTD PMID:27683099 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 increases expression ISO geraniol results in increased expression of SMAD7 mRNA CTD PMID:27683099 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 decreases expression ISO geraniol results in decreased expression of SMARCA2 mRNA CTD PMID:27683099 NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 increases expression ISO geraniol results in increased expression of SMARCAL1 mRNA CTD PMID:27683099 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO geraniol results in decreased expression of SMC4 mRNA CTD PMID:27683099 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Snca synuclein alpha multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein]
geraniol inhibits the reaction [Rotenone results in increased expression of SNCA protein]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Dopamine]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]; geraniol inhibits the reaction [SNCA protein results in increased abundance of Thiobarbituric Acid Reactive Substances]
CTD PMID:24103762 PMID:27026137 PMID:30141137 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD1 mRNA]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD1 protein]
CTD PMID:22509279 PMID:30141137 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 protein]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD2 protein]
CTD PMID:22509279 PMID:30141137 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression ISO geraniol results in decreased expression of SOX9 mRNA CTD PMID:27683099 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp100 SP100 nuclear antigen increases expression ISO geraniol results in increased expression of SP100 mRNA CTD PMID:27683099 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO geraniol results in increased expression of SQSTM1 mRNA
geraniol inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression ISO geraniol results in increased expression of SREBF2 mRNA CTD PMID:23668785 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO geraniol results in increased expression of STAT1 mRNA CTD PMID:27683099 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat2 signal transducer and activator of transcription 2 increases expression ISO geraniol results in increased expression of STAT2 mRNA CTD PMID:27683099 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO geraniol results in increased expression of STAT6 mRNA CTD PMID:27683099 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO geraniol results in decreased expression of STMN1 mRNA CTD PMID:27683099 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sub1 SUB1 regulator of transcription decreases expression ISO geraniol results in decreased expression of SUB1 mRNA CTD PMID:27683099 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436
JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit decreases expression ISO geraniol results in decreased expression of SUPT16H mRNA CTD PMID:27683099 NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit increases expression ISO geraniol results in increased expression of SUPT5H mRNA CTD PMID:27683099 NCBI chr 1:83,586,713...83,616,971
Ensembl chr 1:83,586,718...83,616,892
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO geraniol results in decreased expression of TARDBP mRNA CTD PMID:27683099 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Tceal1 transcription elongation factor A like 1 increases expression ISO geraniol results in increased expression of TCEAL1 mRNA CTD PMID:27683099 NCBI chr  X:100,058,485...100,060,439
Ensembl chr  X:100,058,132...100,060,551
JBrowse link
G Tcf12 transcription factor 12 increases expression ISO geraniol results in increased expression of TCF12 mRNA CTD PMID:27683099 NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201
JBrowse link
G Tcf25 transcription factor 25 increases expression ISO geraniol results in increased expression of TCF25 mRNA CTD PMID:27683099 NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723
JBrowse link
G Tcf4 transcription factor 4 decreases expression ISO geraniol results in decreased expression of TCF4 mRNA CTD PMID:27683099 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tcf7l2 transcription factor 7 like 2 decreases expression ISO geraniol results in decreased expression of TCF7L2 mRNA CTD PMID:27683099 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Terf1 telomeric repeat binding factor 1 decreases expression ISO geraniol results in decreased expression of TERF1 mRNA CTD PMID:27683099 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression ISO geraniol results in increased expression of TFAP2A mRNA CTD PMID:27683099 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tfcp2 transcription factor CP2 decreases expression ISO geraniol results in decreased expression of TFCP2 mRNA CTD PMID:27683099 NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:131,616,785...131,658,939
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression ISO geraniol results in decreased expression of TFDP1 mRNA CTD PMID:27683099 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA] CTD PMID:28428697 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 increases expression ISO geraniol results in increased expression of TGIF1 mRNA CTD PMID:27683099 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:23943375 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Timeless timeless circadian regulator decreases expression ISO geraniol results in decreased expression of TIMELESS mRNA CTD PMID:27683099 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tk1 thymidine kinase 1 decreases expression
multiple interactions
ISO geraniol results in decreased expression of TK1 mRNA
Fluorouracil promotes the reaction [geraniol results in decreased expression of TK1 mRNA]
CTD PMID:15374632 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor increases expression ISO geraniol results in increased expression of TLE1 mRNA CTD PMID:27683099 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein] CTD PMID:29050341 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]
geraniol results in increased expression of TNF mRNA
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of TNF protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; geraniol inhibits the reaction [Fructose results in increased secretion of TNF protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
CTD PMID:21430599 PMID:23399806 PMID:25679220 PMID:26190278 PMID:26695085 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
EXP
ISO
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein]
geraniol results in increased expression of TP53 mRNA
CTD PMID:21907755 PMID:27683099 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO geraniol results in decreased expression of TPX2 mRNA CTD PMID:27683099 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Traip TRAF-interacting protein decreases expression ISO geraniol results in decreased expression of TRAIP mRNA CTD PMID:27683099 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
JBrowse link
G Trak1 trafficking kinesin protein 1 increases expression ISO geraniol results in increased expression of TRAK1 mRNA CTD PMID:27683099 NCBI chr 8:120,984,445...121,139,357
Ensembl chr 8:120,984,431...121,139,367
JBrowse link
G Trim29 tripartite motif-containing 29 increases expression ISO geraniol results in increased expression of TRIM29 mRNA CTD PMID:27683099 NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 increases expression ISO geraniol results in increased expression of TRPS1 mRNA CTD PMID:27683099 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO geraniol binds to and results in increased activity of TRPV1 protein CTD PMID:20686244 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO geraniol results in increased expression of TSC22D3 mRNA CTD PMID:27683099 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO geraniol results in decreased expression of TTK mRNA CTD PMID:27683099 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Tulp3 TUB like protein 3 increases expression ISO geraniol results in increased expression of TULP3 mRNA CTD PMID:27683099 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Tulp4 TUB like protein 4 increases expression ISO geraniol results in increased expression of TULP4 mRNA CTD PMID:27683099 NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688
JBrowse link
G Tyms thymidylate synthetase multiple interactions
decreases expression
ISO Fluorouracil promotes the reaction [geraniol results in decreased expression of TYMS mRNA] CTD PMID:15374632 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO geraniol results in decreased expression of UBE2C mRNA CTD PMID:27683099 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression ISO geraniol results in decreased expression of UBE2N mRNA CTD PMID:27683099 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ubp1 upstream binding protein 1 decreases expression ISO geraniol results in decreased expression of UBP1 mRNA CTD PMID:27683099 NCBI chr 8:113,869,771...113,915,625
Ensembl chr 8:113,869,979...113,915,625
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of UCP2 protein] CTD PMID:26695085 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO geraniol inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 protein]
geraniol inhibits the reaction [Dietary Fats results in increased expression of VCAM1 protein]
CTD PMID:27107694 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of VEGFA protein] CTD PMID:26364502 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO geraniol results in increased expression of VLDLR mRNA CTD PMID:26141755 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO geraniol results in increased expression of XBP1 mRNA CTD PMID:27683099 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 increases expression ISO geraniol results in increased expression of ZBTB1 mRNA CTD PMID:27683099 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression ISO geraniol results in increased expression of ZBTB10 mRNA CTD PMID:27683099 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
JBrowse link
G Zbtb11 zinc finger and BTB domain containing 11 decreases expression ISO geraniol results in decreased expression of ZBTB11 mRNA CTD PMID:27683099 NCBI chr11:44,598,694...44,652,559
Ensembl chr11:44,616,289...44,651,050
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 increases expression ISO geraniol results in increased expression of ZBTB20 mRNA CTD PMID:27683099 NCBI chr11:57,052,129...57,791,214
Ensembl chr11:57,072,880...57,510,210
JBrowse link
G Zfp110 zinc finger protein 110 increases expression ISO geraniol results in increased expression of ZNF274 mRNA CTD PMID:27683099 NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086
JBrowse link
G Zfp189 zinc finger protein 189 increases expression ISO geraniol results in increased expression of ZNF189 mRNA CTD PMID:27683099 NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
JBrowse link
G Zfp207 zinc finger protein 207 decreases expression ISO geraniol results in decreased expression of ZNF207 mRNA CTD PMID:27683099 NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
JBrowse link
G Zfp248 zinc finger protein 248 decreases expression ISO geraniol results in decreased expression of ZNF248 mRNA CTD PMID:27683099 NCBI chr 4:151,605,433...151,630,249
Ensembl chr 4:151,606,495...151,629,850
JBrowse link
G Zfp263 zinc finger protein 263 increases expression ISO geraniol results in increased expression of ZNF263 mRNA CTD PMID:27683099 NCBI chr10:11,764,424...11,774,324
Ensembl chr10:11,764,427...11,771,235
JBrowse link
G Zfp281 zinc finger protein 281 increases expression ISO geraniol results in increased expression of ZNF281 mRNA CTD PMID:27683099 NCBI chr13:48,096,103...48,104,265
Ensembl chr13:48,037,286...48,104,888
JBrowse link
G Zfp329 zinc finger protein 329 increases expression ISO geraniol results in increased expression of ZNF329 mRNA CTD PMID:27683099 NCBI chr 1:73,403,067...73,498,349
Ensembl chr 1:73,402,972...73,422,037
JBrowse link
G Zfp334 zinc finger protein 334 increases expression ISO geraniol results in increased expression of ZNF334 mRNA CTD PMID:27683099 NCBI chr 3:154,112,537...154,125,087
Ensembl chr 3:154,113,561...154,125,057
JBrowse link
G Zfp354a zinc finger protein 354A increases expression ISO geraniol results in increased expression of ZNF354A mRNA CTD PMID:27683099 NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
JBrowse link
G Zfp394 zinc finger protein 394 increases expression ISO geraniol results in increased expression of ZNF394 mRNA CTD PMID:27683099 NCBI chr12:9,409,047...9,417,228
Ensembl chr12:9,409,078...9,417,246
JBrowse link
G Zfp410 zinc finger protein 410 increases expression ISO geraniol results in increased expression of ZNF410 mRNA CTD PMID:27683099 NCBI chr 6:103,963,265...103,990,252
Ensembl chr 6:103,964,060...103,990,225
JBrowse link
G Zfp455l1 zinc finger protein 455 like 1 increases expression ISO geraniol results in increased expression of KRBOX4 mRNA CTD PMID:27683099 NCBI chr 1:34,866,934...34,944,939
Ensembl chr 1:34,927,303...34,944,121
JBrowse link
G Zfp467 zinc finger protein 467 increases expression ISO geraniol results in increased expression of ZNF467 mRNA CTD PMID:27683099 NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
JBrowse link
G Zfp606 zinc finger protein 606 increases expression ISO geraniol results in increased expression of ZNF606 mRNA CTD PMID:27683099 NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072
JBrowse link
G Zfp612 zinc finger protein 612 increases expression ISO geraniol results in increased expression of ZNF23 mRNA CTD PMID:27683099 NCBI chr19:38,053,953...38,071,196
Ensembl chr19:38,053,967...38,067,455
JBrowse link
G Zfp68 zinc finger protein 68 increases expression ISO geraniol results in increased expression of ZNF84 mRNA CTD PMID:27683099 NCBI chr12:16,026,058...16,040,995
Ensembl chr12:16,026,079...16,040,995
JBrowse link
G Zfp75d zinc finger protein 75D increases expression ISO geraniol results in increased expression of ZNF75D mRNA CTD PMID:27683099 NCBI chr  X:134,035,116...134,053,765
Ensembl chr  X:134,036,143...134,051,519
JBrowse link
G Zfp768 zinc finger protein 768 increases expression ISO geraniol results in increased expression of ZNF768 mRNA CTD PMID:27683099 NCBI chr 1:181,966,314...181,968,950
Ensembl chr 1:181,966,316...181,969,147
JBrowse link
G Zhx2 zinc fingers and homeoboxes 2 increases expression ISO geraniol results in increased expression of ZHX2 mRNA CTD PMID:27683099 NCBI chr 7:89,226,358...89,374,266
Ensembl chr 7:89,226,463...89,374,378
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 increases expression ISO geraniol results in increased expression of ZMIZ1 mRNA CTD PMID:27683099 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
JBrowse link
G Zmym4 zinc finger MYM-type containing 4 increases expression ISO geraniol results in increased expression of ZMYM4 mRNA CTD PMID:27683099 NCBI chr 5:139,146,782...139,264,387
Ensembl chr 5:139,146,665...139,264,421
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 increases expression ISO geraniol results in increased expression of ZMYND11 mRNA CTD PMID:27683099 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902
JBrowse link
G Zscan18 zinc finger and SCAN domain containing 18 increases expression ISO geraniol results in increased expression of ZSCAN18 mRNA CTD PMID:27683099 NCBI chr 1:73,332,883...73,349,846
Ensembl chr 1:73,332,889...73,345,897
JBrowse link
G Zzz3 zinc finger, ZZ-type containing 3 increases expression ISO geraniol results in increased expression of ZZZ3 mRNA CTD PMID:27683099 NCBI chr 2:241,330,366...241,397,308
Ensembl chr 2:241,331,022...241,397,307
JBrowse link
geranyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO geranyl acetate results in increased expression of BAX protein CTD PMID:29745075 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO geranyl acetate results in decreased expression of BCL2 protein CTD PMID:29745075 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
geranyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases abundance
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; Lovastatin inhibits the reaction [HMGCR protein results in increased abundance of geranyl diphosphate] CTD PMID:19819230 PMID:19856009 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO geranyl diphosphate results in decreased activity of MVK protein
geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form CTD PMID:19819230 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
HU-308 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of ARG1 mRNA] CTD PMID:29560022 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]] CTD PMID:27611972 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Becn1 beclin 1 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of BECN1 protein; HU 308 inhibits the reaction [Glucose results in decreased expression of BECN1 protein]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein] CTD PMID:27611972 PMID:30459625 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Casp1 caspase 1 multiple interactions ISO 3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein]; [HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein] CTD PMID:27611972 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO HU 308 inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] CTD PMID:34537380 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cd68 Cd68 molecule multiple interactions EXP HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CD68 protein] CTD PMID:29560022 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Chi3l3 chitinase 3-like 3 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CHI3L3 mRNA] CTD PMID:29560022 NCBI chr 2:193,808,135...193,825,511
Ensembl chr 2:193,812,431...193,825,513
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions EXP
ISO
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 mRNA]; HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 protein]
[HU 308 co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CNR2 mRNA; HU 308 binds to and results in increased activity of CNR2 protein
CTD PMID:27194477 PMID:29560022 PMID:30232034 PMID:34537380 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO HU 308 inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA] CTD PMID:34537380 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 protein]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 mRNA]
CTD PMID:29560022 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B mRNA]
HU 308 inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; HU 308 inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]
3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein]; [HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]]; HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]
CTD PMID:27611972 PMID:29560022 PMID:34537380 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 mRNA]
HU 308 inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 protein]
CTD PMID:29560022 PMID:34537380 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA] CTD PMID:34537380 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA] CTD PMID:34537380 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of MRC1 protein] CTD PMID:29560022 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein]; HU 308 inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]
CTD PMID:29560022 PMID:30459625 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of NFKBIA protein] CTD PMID:29560022 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of NLRP3 protein CTD PMID:27611972 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of NOS2 protein] CTD PMID:29560022 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of PIK3R1 protein] CTD PMID:29560022 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of SQSTM1 protein; HU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein] CTD PMID:27611972 PMID:30459625 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 mRNA]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 protein]
CTD PMID:29560022 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF mRNA]
HU 308 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF protein]
CTD PMID:29560022 PMID:34537380 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
nerolidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP [nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein; nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein]; nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:33212213 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein] CTD PMID:33212213 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO nerolidol results in increased expression of BAX mRNA CTD PMID:35357761 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO nerolidol results in decreased expression of BCL2 mRNA CTD PMID:35357761 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 increases expression ISO nerolidol results in increased expression of CASP3 mRNA CTD PMID:35357761 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein] CTD PMID:33212213 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO nerolidol results in decreased expression of CCND1 mRNA CTD PMID:35357761 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP [nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein CTD PMID:33212213 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Il6 interleukin 6 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein] CTD PMID:33212213 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:33212213 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:33212213 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO nerolidol results in increased expression of and results in increased phosphorylation of MAPK8 mRNA CTD PMID:35357761 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein] CTD PMID:33212213 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein] CTD PMID:33212213 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:33212213 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein] CTD PMID:33212213 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein] CTD PMID:33212213 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein] CTD PMID:33212213 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein] CTD PMID:33212213 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein] CTD PMID:33212213 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein] CTD PMID:33212213 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
piericidin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau increases response to substance
increases phosphorylation
ISO MAPT protein polymorphism results in increased susceptibility to piericidin A
piericidin A results in increased phosphorylation of MAPT protein polymorphism
CTD PMID:25437199 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
pravastatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases expression
decreases expression
EXP
ISO
[[colestimide co-treated with Pravastatin] results in increased expression of ABCA1 protein] which results in decreased abundance of Cholesterol; [colestimide co-treated with Pravastatin] affects the expression of ABCA1 mRNA; [colestimide co-treated with Pravastatin] affects the expression of ABCA1 protein
cotreatment with pravastatin and colestimide increases expression of abca1 mRNA and protein in rat liver; and decreases expression of abca1 mRNA and protein in rat small intestine
Pravastatin results in decreased expression of ABCA1
CTD
RGD
PMID:17526932 PMID:19461118 PMID:17526932 RGD:2308820 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
affects import
ISO Pravastatin inhibits the reaction [ABCB11 protein affects the import of Taurocholic Acid]
ABCB11 protein affects the import of Pravastatin
CTD PMID:15901796 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport ISO ABCB1 protein results in increased transport of Pravastatin; ABCB1 protein results in increased transport of Pravastatin analog CTD PMID:15616150 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Pravastatin results in increased expression of ABCB4 mRNA CTD PMID:15242490 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
increases expression
multiple interactions
affects transport
ISO
EXP
ABCC2 protein affects the export of Pravastatin
Pravastatin results in increased expression of ABCC2 protein
ABCC2 protein binds to and results in increased uptake of Pravastatin analog; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]
ABCC2 protein affects the transport of Pravastatin
CTD PMID:15901800 PMID:15955871 PMID:23562342 PMID:24909372 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Pravastatin results in increased expression of ABCC3 protein CTD PMID:24909372 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Pravastatin CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 decreases expression ISO Pravastatin results in decreased expression of ABCD3 mRNA CTD PMID:27225895 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects export
increases activity
ISO ABCG2 protein affects the export of Pravastatin
Pravastatin results in increased activity of ABCG2 protein
CTD PMID:15901800 PMID:27475308 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Pravastatin results in increased expression of ABCG5 mRNA CTD PMID:15242490 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Pravastatin results in increased expression of ABCG8 mRNA CTD PMID:15242490 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO Pravastatin results in decreased expression of ACAA1B mRNA CTD PMID:27225895 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression EXP
ISO
Pravastatin results in decreased expression of ACAA2 mRNA CTD PMID:27225895 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression ISO
EXP
Pravastatin results in decreased expression of ACAT1 mRNA CTD PMID:27225895 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein] CTD PMID:29682576 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions EXP [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein] CTD PMID:29682576 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of ACOT1 mRNA
Pravastatin results in decreased expression of ACOT1 mRNA
CTD PMID:27225895 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot12 acyl-CoA thioesterase 12 decreases expression ISO
EXP
Pravastatin results in decreased expression of ACOT12 mRNA CTD PMID:27225895 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acot2 acyl-CoA thioesterase 2 affects expression ISO Pravastatin affects the expression of ACOT2 mRNA CTD PMID:27225895 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acot3 acyl-CoA thioesterase 3 decreases expression ISO Pravastatin results in decreased expression of ACOT3 mRNA CTD PMID:27225895 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
Ensembl chr 6:103,682,596...103,688,427
JBrowse link
G Acot4 acyl-CoA thioesterase 4 decreases expression ISO Pravastatin results in decreased expression of ACOT4 mRNA CTD PMID:27225895 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO
EXP
Pravastatin results in decreased expression of ACOX1 mRNA CTD PMID:27225895 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of ACSF2 mRNA
Pravastatin results in decreased expression of ACSF2 mRNA
CTD PMID:27225895 NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Pravastatin results in decreased expression of ACSL1 mRNA CTD PMID:27225895 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression EXP
ISO
Pravastatin results in decreased expression of ACTA1 mRNA CTD PMID:27225895 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Adamdec1 ADAM-like, decysin 1 increases expression ISO
EXP
Pravastatin results in increased expression of ADAMDEC1 mRNA CTD PMID:27225895 NCBI chr15:42,900,629...42,921,684
Ensembl chr15:42,900,636...42,921,712
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO
EXP
Pravastatin results in decreased expression of ADH1 mRNA CTD PMID:27225895 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression EXP
ISO
Pravastatin results in decreased expression of ADH7 mRNA CTD PMID:27225895 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link
G Agt angiotensinogen decreases expression EXP
ISO
Pravastatin results in decreased expression of AGT mRNA CTD PMID:27225895 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of AIF1 mRNA CTD PMID:27225895 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression ISO
EXP
Pravastatin results in decreased expression of AKR1C18 mRNA
Pravastatin results in decreased expression of AKR1C3 mRNA
CTD PMID:27225895 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
Pravastatin inhibits the reaction [Carboplatin results in increased activity of and results in increased phosphorylation of AKT1 protein]
[Pravastatin co-treated with olmesartan] results in increased phosphorylation of AKT1 protein; [resveratrol co-treated with Pravastatin] results in increased phosphorylation of AKT1 protein
Pravastatin results in increased phosphorylation of AKT1 protein
CTD PMID:17170375 PMID:17188708 PMID:18483861 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO
EXP
Pravastatin results in decreased expression of ALDH1A1 mRNA CTD PMID:16763553 PMID:27225895 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions
decreases expression
ISO Cholesterol, Dietary inhibits the reaction [Pravastatin results in decreased expression of ALDH1A2 mRNA] CTD PMID:16763553 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects expression EXP
ISO
Pravastatin affects the expression of ALDH1A3 mRNA CTD PMID:27225895 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldoart2 aldolase 1 A retrogene 2 increases expression
decreases expression
ISO
EXP
Pravastatin results in increased expression of ALDOART2 mRNA
Pravastatin results in decreased expression of ALDOART2 mRNA
CTD PMID:27225895 NCBI chr 6:72,939,821...72,941,511
Ensembl chr 6:72,939,788...72,941,709
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases expression EXP
ISO
Pravastatin results in increased expression of AMPD3 mRNA CTD PMID:27225895 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO
EXP
Pravastatin results in decreased expression of ANGPTL3 mRNA CTD PMID:27225895 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Ank2 ankyrin 2 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of ANK2 mRNA
Pravastatin results in decreased expression of ANK2 mRNA
CTD PMID:27225895 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Anks6 ankyrin repeat and sterile alpha motif domain containing 6 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of ANKS6 mRNA
Pravastatin results in decreased expression of ANKS6 mRNA
CTD PMID:27225895 NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596
JBrowse link
G Apoa1 apolipoprotein A1 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of APOA1 mRNA
Pravastatin results in decreased expression of APOA1 mRNA
CTD PMID:27225895 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G App amyloid beta precursor protein increases expression ISO Pravastatin results in increased expression of APP CTD PMID:19461118 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arg2 arginase 2 increases expression ISO Pravastatin results in increased expression of ARG2 mRNA CTD PMID:27225895 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression
affects expression
EXP
ISO
Pravastatin results in decreased expression of ARHGAP11A mRNA
Pravastatin affects the expression of ARHGAP11A mRNA
CTD PMID:27225895 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression EXP
ISO
Pravastatin results in decreased expression of ARRDC3 mRNA CTD PMID:27225895 NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha decreases expression ISO
EXP
Pravastatin results in decreased expression of ATP4A mRNA CTD PMID:27225895 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of ATP6V0D2 mRNA
Pravastatin results in decreased expression of ATP6V0D2 mRNA
CTD PMID:27225895 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Axin2 axin 2 decreases expression EXP
ISO
Pravastatin results in decreased expression of AXIN2 mRNA CTD PMID:27225895 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression
affects expression
EXP
ISO
Pravastatin results in decreased expression of BARD1 mRNA
Pravastatin affects the expression of BARD1 mRNA
CTD PMID:27225895 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [LDLR gene mutant form results in increased susceptibility to Pravastatin] which affects the expression of BAX protein CTD PMID:26875785 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [LDLR gene mutant form results in increased susceptibility to Pravastatin] which affects the expression of BCL2 protein CTD PMID:26875785 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 decreases expression EXP
ISO
Pravastatin results in decreased expression of BHLHA15 mRNA CTD PMID:27225895 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
JBrowse link
G Bmal2 basic helix-loop-helix ARNT like 2 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of BMAL2 mRNA
Pravastatin results in increased expression of BMAL2 mRNA
CTD PMID:27225895 NCBI chr 4:179,699,432...179,747,710
Ensembl chr 4:179,699,502...179,746,949
JBrowse link
G Bmper BMP-binding endothelial regulator affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of BMPER mRNA
Pravastatin results in increased expression of BMPER mRNA
CTD PMID:27225895 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of BUB1B mRNA
Pravastatin results in decreased expression of BUB1B mRNA
CTD PMID:27225895 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C1qb complement C1q B chain decreases expression ISO
EXP
Pravastatin results in decreased expression of C1QB mRNA CTD PMID:27225895 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G C1qc complement C1q C chain decreases expression EXP
ISO
Pravastatin results in decreased expression of C1QC mRNA CTD PMID:27225895 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G C5ar1 complement C5a receptor 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of C5AR1 mRNA CTD PMID:27225895 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO
EXP
[LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in increased cleavage of CASP3 protein; Pravastatin inhibits the reaction [Carboplatin results in increased expression of CASP3 protein]
Pravastatin results in increased cleavage of CASP3 protein
Pravastatin inhibits the reaction [Carboplatin results in increased expression of CASP3 protein]; Pravastatin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]
CTD PMID:18483861 PMID:20368269 PMID:26875785 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Pravastatin inhibits the reaction [Carboplatin results in increased expression of CASP9 protein] CTD PMID:18483861 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases activity ISO Pravastatin results in increased activity of CAT protein CTD PMID:17479860 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl12 C-C motif chemokine ligand 12 decreases expression ISO
EXP
Pravastatin results in decreased expression of CCL12 mRNA CTD PMID:27225895 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Pravastatin inhibits the reaction [LEP gene mutant form results in increased expression of CCL2 mRNA]; Pravastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
Pravastatin inhibits the reaction [lopinavir-ritonavir drug combination results in increased secretion of CCL2 protein]; Pravastatin inhibits the reaction [Ritonavir results in increased secretion of CCL2 protein]
CTD PMID:18323514 PMID:20884875 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 decreases expression ISO
EXP
Pravastatin results in decreased expression of CCL6 mRNA CTD PMID:27225895 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Cd209d CD209d molecule decreases expression EXP Pravastatin results in decreased expression of CD209 mRNA CTD PMID:27225895 NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171
JBrowse link
G Cd28 Cd28 molecule decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of CD28 mRNA
Pravastatin affects the expression of CD28 mRNA
CTD PMID:27225895 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd40 CD40 molecule affects expression EXP
ISO
Pravastatin affects the expression of CD40 mRNA CTD PMID:27225895 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd7 Cd7 molecule decreases expression EXP
ISO
Pravastatin results in decreased expression of CD7 mRNA CTD PMID:27225895 NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967
JBrowse link
G Cdc27 cell division cycle 27 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of CDC27 mRNA
Pravastatin results in increased expression of CDC27 mRNA
CTD PMID:27225895 NCBI chr10:89,400,720...89,449,816
Ensembl chr10:89,400,940...89,449,736
JBrowse link
G Cdc6 cell division cycle 6 decreases expression
affects expression
EXP
ISO
Pravastatin results in decreased expression of CDC6 mRNA
Pravastatin affects the expression of CDC6 mRNA
CTD PMID:27225895 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdca7l cell division cycle associated 7 like affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of CDCA7L mRNA
Pravastatin results in decreased expression of CDCA7L mRNA
CTD PMID:27225895 NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
JBrowse link
G Cdhr5 cadherin-related family member 5 decreases expression
increases expression
ISO
EXP
Pravastatin results in decreased expression of CDHR5 mRNA
Pravastatin results in increased expression of CDHR5 mRNA
CTD PMID:27225895 NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Pravastatin inhibits the reaction [Benzo(a)pyrene results in decreased degradation of CDKN1A protein]; Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein] CTD PMID:15625077 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 increases expression ISO
EXP
Pravastatin results in increased expression of CDS1 mRNA CTD PMID:27225895 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Pravastatin results in increased expression of CEBPD mRNA CTD PMID:27225895 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cers6 ceramide synthase 6 decreases expression ISO Pravastatin results in decreased expression of CERS6 mRNA CTD PMID:27225895 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848
JBrowse link
G Cesl1 carboxylesterase-like 1 decreases expression EXP Pravastatin results in decreased expression of CESL1 mRNA CTD PMID:27225895 NCBI chr19:22,670,709...23,006,329
Ensembl chr19:22,670,712...22,712,608
JBrowse link
G Cfap96 cilia and flagella associated protein 96 increases expression EXP Pravastatin results in increased expression of CFAP96 mRNA CTD PMID:27225895 NCBI chr16:46,291,075...46,315,616
Ensembl chr16:46,291,311...46,315,625
JBrowse link
G Cip2a cellular inhibitor of PP2A decreases expression EXP Pravastatin results in decreased expression of CIP2A mRNA CTD PMID:27225895 NCBI chr11:51,792,143...51,823,016
Ensembl chr11:51,795,024...51,822,938
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 decreases expression
increases expression
ISO
EXP
Pravastatin results in decreased expression of CITED1 mRNA
Pravastatin results in increased expression of CITED1 mRNA
CTD PMID:27225895 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression ISO
EXP
Pravastatin results in increased expression of CLCN6 mRNA CTD PMID:27225895 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP
ISO
Pravastatin results in decreased expression of CLEC4F mRNA CTD PMID:27225895 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Clec4m C-type lectin domain family 4 member M decreases expression ISO Pravastatin results in decreased expression of CD209 mRNA CTD PMID:27225895 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539
JBrowse link
G Clstn3 calsyntenin 3 decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of CLSTN3 mRNA
Pravastatin affects the expression of CLSTN3 mRNA
CTD PMID:27225895 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
JBrowse link
G Cnn1 calponin 1 decreases expression ISO
EXP
Pravastatin results in decreased expression of CNN1 mRNA CTD PMID:27225895 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of CPT1B mRNA
Pravastatin affects the expression of CPT1B mRNA
CTD PMID:27225895 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Pravastatin results in decreased expression of CPT2 mRNA CTD PMID:27225895 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crat carnitine O-acetyltransferase increases expression
affects expression
EXP
ISO
Pravastatin results in increased expression of CRAT mRNA
Pravastatin affects the expression of CRAT mRNA
CTD PMID:27225895 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of CREB3L3 mRNA
Pravastatin affects the expression of CREB3L3 mRNA
CTD PMID:27225895 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
JBrowse link
G Crp C-reactive protein decreases expression
increases expression
ISO
EXP
Pravastatin results in decreased expression of CRP mRNA
Pravastatin results in increased expression of CRP mRNA
CTD PMID:27225895 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP
ISO
Pravastatin results in decreased expression of CSAD mRNA CTD PMID:27225895 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP
ISO
Pravastatin results in decreased expression of CSF1R mRNA CTD PMID:27225895 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of CSMD1 mRNA CTD PMID:27225895 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Ctnnb1 catenin beta 1 affects localization
multiple interactions
EXP Pravastatin affects the localization of CTNNB1 protein
[resveratrol co-treated with Pravastatin] affects the localization of CTNNB1 protein
CTD PMID:17188708 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of CXCL2 mRNA
Pravastatin results in increased expression of CXCL2 mRNA
CTD PMID:27225895 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression EXP Pravastatin results in decreased expression of CYBA protein CTD PMID:17170375 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP Pravastatin inhibits the reaction [Carboplatin results in increased expression of CYCS protein] CTD PMID:18483861 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP
ISO
Pravastatin results in decreased expression of CYP1A2 mRNA CTD PMID:27225895 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of CYP1B1 mRNA
Pravastatin results in increased expression of CYP1B1 mRNA
CTD PMID:27225895 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 decreases expression EXP Pravastatin results in decreased expression of CYP2B21 mRNA CTD PMID:27225895 NCBI chr 1:81,886,097...81,915,066
Ensembl chr 1:81,886,098...81,915,066
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression ISO Pravastatin affects the expression of CYP2B10 mRNA CTD PMID:27225895 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 decreases expression EXP Pravastatin results in decreased expression of CYP2D3 mRNA CTD PMID:27225895 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases expression EXP Pravastatin results in decreased expression of CYP2J4 mRNA CTD PMID:27225895 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression EXP Pravastatin results in decreased expression of CYP3A23-3A1 mRNA CTD PMID:27225895 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP Pravastatin results in decreased expression of CYP4A1 mRNA CTD PMID:27225895 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 affects expression EXP Pravastatin affects the expression of CYP4A2 mRNA CTD PMID:27225895 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP Pravastatin results in decreased expression of CYP4A3 mRNA CTD PMID:27225895 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP
ISO
Pravastatin results in increased expression of CYP51 mRNA CTD PMID:27225895 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of DECR1 mRNA CTD PMID:27225895 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Depdc1b DEP domain containing 1B decreases expression
affects expression
EXP
ISO
Pravastatin results in decreased expression of DEPDC1B mRNA
Pravastatin affects the expression of DEPDC1B mRNA
CTD PMID:27225895 NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
JBrowse link
G Derl3 derlin 3 decreases expression EXP
ISO
Pravastatin results in decreased expression of DERL3 mRNA CTD PMID:27225895 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases expression ISO
EXP
Pravastatin results in decreased expression of DIO3 mRNA CTD PMID:27225895 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Dlgap1 DLG associated protein 1 increases expression EXP
ISO
Pravastatin results in increased expression of DLGAP1 mRNA CTD PMID:27225895 NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 affects farnesylation ISO Pravastatin affects the farnesylation of DNAJA1 protein CTD PMID:20884875 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnase2b deoxyribonuclease 2 beta increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of DNASE2B mRNA
Pravastatin results in decreased expression of DNASE2B mRNA
CTD PMID:27225895 NCBI chr 2:235,470,915...235,515,211
Ensembl chr 2:235,470,919...235,486,295
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression EXP
ISO
Pravastatin results in increased expression of DPYSL2 mRNA CTD PMID:27225895 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression
affects expression
EXP
ISO
Pravastatin results in decreased expression of DTL mRNA
Pravastatin affects the expression of DTL mRNA
CTD PMID:27225895 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of ECH1 mRNA CTD PMID:27225895 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Edn1 endothelin 1 decreases expression ISO
EXP
Pravastatin results in decreased expression of EDN1 protein
Pravastatin results in decreased expression of EDN1 mRNA; Pravastatin results in decreased expression of EDN1 protein
CTD PMID:12105140 PMID:19812503 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Efhb EF hand domain family, member B increases expression ISO
EXP
Pravastatin results in increased expression of EFHB mRNA CTD PMID:27225895 NCBI chr 9:6,372,191...6,441,678
Ensembl chr 9:6,372,194...6,441,919
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression EXP
ISO
Pravastatin results in decreased expression of EHHADH mRNA CTD PMID:27225895 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 affects expression
decreases expression
EXP
ISO
Pravastatin affects the expression of ENPP5 mRNA
Pravastatin results in decreased expression of ENPP5 mRNA
CTD PMID:27225895 NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression
increases expression
ISO
EXP
Pravastatin results in decreased expression of ENTPD2 mRNA
Pravastatin results in increased expression of ENTPD2 mRNA
CTD PMID:27225895 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO
EXP
Pravastatin results in decreased expression of EPHX2 mRNA CTD PMID:27225895 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Ephx4 epoxide hydrolase 4 increases expression
affects expression
EXP
ISO
Pravastatin results in increased expression of EPHX4 mRNA
Pravastatin affects the expression of EPHX4 mRNA
CTD PMID:27225895 NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022
JBrowse link
G Evi2a ecotropic viral integration site 2A decreases expression ISO
EXP
Pravastatin results in decreased expression of EVI2A mRNA CTD PMID:27225895 NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
JBrowse link
G F13a1 coagulation factor XIII A1 chain decreases expression ISO
EXP
Pravastatin results in decreased expression of F13A1 mRNA CTD PMID:27225895 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO Pravastatin results in decreased expression of FABP1 mRNA CTD PMID:27225895 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp2 fatty acid binding protein 2 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of FABP2 mRNA
Pravastatin results in decreased expression of FABP2 mRNA
CTD PMID:27225895 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO
EXP
Pravastatin results in increased expression of FABP5 mRNA CTD PMID:27225895 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Far1 fatty acyl CoA reductase 1 increases expression EXP
ISO
Pravastatin results in increased expression of FAR1 mRNA CTD PMID:27225895 NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
JBrowse link
G Fbn1 fibrillin 1 increases expression ISO Pravastatin results in increased expression of FBN1 mRNA CTD PMID:27225895 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbp2 fructose-bisphosphatase 2 affects expression EXP Pravastatin affects the expression of FBP2 mRNA CTD PMID:27225895 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects activity ISO Pravastatin affects the activity of FDFT1 protein CTD PMID:8517861 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 decreases expression ISO
EXP
Pravastatin results in decreased expression of FGD2 mRNA CTD PMID:27225895 NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603
JBrowse link
G Fgf13 fibroblast growth factor 13 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of FGF13 mRNA
Pravastatin results in increased expression of FGF13 mRNA
CTD PMID:27225895 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 increases expression EXP
ISO
Pravastatin results in increased expression of FLACC1 mRNA CTD PMID:27225895 NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648
JBrowse link
G Flot1 flotillin 1 decreases expression ISO Pravastatin results in decreased expression of FLOT1 protein CTD PMID:12628479 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Folr2 folate receptor beta decreases expression EXP
ISO
Pravastatin results in decreased expression of FOLR2 mRNA CTD PMID:27225895 NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724
JBrowse link
G Foxo1 forkhead box O1 decreases phosphorylation ISO Pravastatin results in decreased phosphorylation of FOXO1 protein CTD PMID:33034787 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Gck glucokinase decreases expression EXP Pravastatin results in decreased expression of GCK mRNA CTD PMID:27225895 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
decreases expression
ISO
EXP
Pravastatin results in increased expression of GCLC mRNA
Pravastatin results in decreased expression of GCLC mRNA
CTD PMID:27225895 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression
decreases expression
ISO
EXP
Pravastatin results in increased expression of GCNT2 mRNA
Pravastatin results in decreased expression of GCNT2 mRNA
CTD PMID:27225895 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions ISO Pravastatin inhibits the reaction [lopinavir-ritonavir drug combination results in increased activity of GLB1 protein]; Pravastatin inhibits the reaction [Ritonavir results in increased activity of GLB1 protein] CTD PMID:20884875 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gldc glycine decarboxylase decreases expression ISO
EXP
Pravastatin results in decreased expression of GLDC mRNA CTD PMID:27225895 NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
JBrowse link
G Gls2 glutaminase 2 decreases expression ISO
EXP
Pravastatin results in decreased expression of GLS2 mRNA CTD PMID:27225895 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Gpr85 G protein-coupled receptor 85 increases expression EXP
ISO
Pravastatin results in increased expression of GPR85 mRNA CTD PMID:27225895 NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of GSTK1 mRNA CTD PMID:27225895 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO
EXP
Pravastatin results in decreased expression of HADH mRNA CTD PMID:27225895 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP
ISO
Pravastatin results in decreased expression of HADHA mRNA CTD PMID:27225895 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP
ISO
Pravastatin results in decreased expression of HADHB mRNA CTD PMID:27225895 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP
ISO
Pravastatin results in increased expression of HAMP mRNA CTD PMID:27225895 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hax1 HCLS1 associated protein X-1 multiple interactions EXP Pravastatin inhibits the reaction [Carboplatin results in decreased expression of HAX1 protein] CTD PMID:18483861 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases response to substance
increases expression
decreases activity
affects expression
ISO
EXP
HMGCR gene SNP results in decreased susceptibility to Pravastatin
Pravastatin results in increased expression of HMGCR mRNA
Pravastatin results in decreased activity of HMGCR protein
Pravastatin affects the expression of HMGCR mRNA
CTD PMID:8517861 PMID:8593127 PMID:15199031 PMID:27225895 PMID:29969672 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Pravastatin results in increased expression of HMGCS1 mRNA CTD PMID:27225895 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP
ISO
[[Pravastatin co-treated with pirinixic acid] co-treated with [RXRA protein co-treated with PPARA protein]] results in increased expression of HMOX1 mRNA; [Pravastatin co-treated with [RXRA protein co-treated with PPARA protein]] results in increased expression of HMOX1 mRNA; [Pravastatin co-treated with pirinixic acid] results in increased expression of HMOX1 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Pravastatin results in increased expression of HMOX1 protein]; Pravastatin promotes the reaction [PPARA protein binds to HMOX1 promoter] CTD PMID:20368269 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hopx HOP homeobox decreases expression ISO
EXP
Pravastatin results in decreased expression of HOPX mRNA CTD PMID:27225895 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909
JBrowse link
G Hrg histidine-rich glycoprotein decreases expression ISO
EXP
Pravastatin results in decreased expression of HRG mRNA CTD PMID:27225895 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO
EXP
Pravastatin results in increased expression of HSD17B7 mRNA CTD PMID:27225895 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 decreases expression
increases expression
ISO
EXP
Pravastatin results in decreased expression of HSDL2 mRNA
Pravastatin results in increased expression of HSDL2 mRNA
CTD PMID:27225895 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP
ISO
Pravastatin results in increased expression of IDI1 mRNA CTD PMID:27225895 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Pravastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA] CTD PMID:18323514 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Il1b interleukin 1 beta decreases expression
increases expression
EXP
ISO
Pravastatin results in decreased expression of IL1B mRNA
Pravastatin results in increased expression of IL1B mRNA
CTD PMID:27225895 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO Pravastatin inhibits the reaction [LEP gene mutant form results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]; Pravastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]
Pravastatin inhibits the reaction [lopinavir-ritonavir drug combination results in increased secretion of IL6 protein]; Pravastatin inhibits the reaction [Ritonavir results in increased secretion of IL6 protein]
Pravastatin results in decreased expression of IL6 protein
CTD PMID:17729120 PMID:18323514 PMID:19330073 PMID:20884875 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions
increases response to substance
EXP
ISO
[INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]
[LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of INS1 protein
[LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in increased susceptibility to INS1 protein
CTD PMID:26875785 PMID:29682576 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO Pravastatin inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein] CTD PMID:18323514 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions EXP
ISO
geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein] CTD PMID:12500026 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions EXP
ISO
geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein] CTD PMID:12500026 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb6 integrin subunit beta 6 affects expression ISO Pravastatin affects the expression of ITGB6 mRNA CTD PMID:27225895 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Kcns3 potassium voltage-gated channel, modifier subfamily S, member 3 increases expression ISO
EXP
Pravastatin results in increased expression of KCNS3 mRNA CTD PMID:27225895 NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:33,808,216...33,865,125
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO
EXP
Pravastatin results in decreased expression of KCTD12 mRNA CTD PMID:27225895 NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282
JBrowse link
G Kif20a kinesin family member 20A affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of KIF20A mRNA
Pravastatin results in decreased expression of KIF20A mRNA
CTD PMID:27225895 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif20b kinesin family member 20B affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of KIF20B mRNA
Pravastatin results in decreased expression of KIF20B mRNA
CTD PMID:27225895 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kif23 kinesin family member 23 affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of KIF23 mRNA
Pravastatin results in decreased expression of KIF23 mRNA
CTD PMID:27225895 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kitlg KIT ligand increases expression
affects expression
EXP
ISO
Pravastatin results in increased expression of KITLG mRNA
Pravastatin affects the expression of KITL mRNA
CTD PMID:27225895 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klb klotho beta decreases expression ISO
EXP
Pravastatin results in decreased expression of KLB mRNA CTD PMID:27225895 NCBI chr14:42,899,050...42,950,788
Ensembl chr14:42,899,510...42,950,799
JBrowse link
G Krt23 keratin 23 decreases expression EXP
ISO
Pravastatin results in decreased expression of KRT23 mRNA CTD PMID:27225895 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983
JBrowse link
G Ldlr low density lipoprotein receptor increases activity
increases response to substance
multiple interactions
ISO Pravastatin results in increased activity of LDLR protein
[LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in increased susceptibility to INS1 protein; LDLR gene mutant form results in increased susceptibility to Pravastatin
[LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which affects the expression of BAX protein; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which affects the expression of BCL2 protein; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of INS1 protein; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of SNAP25 protein; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of STX1A protein; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of VAMP2 protein; [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in increased cleavage of CASP3 protein
CTD PMID:8593127 PMID:26875785 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO Pravastatin inhibits the reaction [LEP gene mutant form results in increased expression of CCL2 mRNA]; Pravastatin inhibits the reaction [LEP gene mutant form results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [LEP gene mutant form results in increased expression of TNF mRNA] CTD PMID:18323514 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals4 galectin 4 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of LGALS4 mRNA
Pravastatin results in decreased expression of LGALS4 mRNA
CTD PMID:27225895 NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481
JBrowse link
G Lgi2 leucine-rich repeat LGI family, member 2 increases expression EXP
ISO
Pravastatin results in increased expression of LGI2 mRNA CTD PMID:27225895 NCBI chr14:58,415,965...58,443,450
Ensembl chr14:58,415,965...58,443,407
JBrowse link
G Lmna lamin A/C increases expression ISO Pravastatin results in increased expression of LMNA protein CTD PMID:20884875 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lpl lipoprotein lipase decreases expression EXP
ISO
Pravastatin results in decreased expression of LPL mRNA CTD PMID:27225895 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrmda leucine rich melanocyte differentiation associated decreases expression ISO Pravastatin results in decreased expression of LRMDA mRNA CTD PMID:27225895 NCBI chr15:1,223,098...2,284,764
Ensembl chr15:1,225,710...2,284,749
JBrowse link
G Lss lanosterol synthase increases expression EXP
ISO
Pravastatin results in increased expression of LSS mRNA CTD PMID:27225895 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 increases expression EXP
ISO
Pravastatin results in increased expression of LTBP2 mRNA CTD PMID:27225895 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression ISO
EXP
Pravastatin results in decreased expression of LY86 mRNA CTD PMID:27225895 NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260
JBrowse link
G Mapt microtubule-associated protein tau affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of MAPT
Pravastatin results in decreased expression of MAPT mRNA
CTD PMID:19461118 PMID:27225895 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of MASTL mRNA
Pravastatin results in decreased expression of MASTL mRNA
CTD PMID:27225895 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Mdm2 MDM2 proto-oncogene increases phosphorylation
increases expression
multiple interactions
ISO
EXP
Pravastatin results in increased phosphorylation of MDM2 protein
Pravastatin results in increased expression of MDM2 protein
[Pravastatin results in increased phosphorylation of MDM2 protein] which results in increased degradation of TP53 protein; Sirolimus inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein]; U 0126 inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein]
CTD PMID:15625077 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Meiob meiosis specific with OB-fold decreases expression
increases expression
ISO
EXP
Pravastatin results in decreased expression of MEIOB mRNA
Pravastatin results in increased expression of MEIOB mRNA
CTD PMID:27225895 NCBI chr10:13,833,170...13,865,684
Ensembl chr10:13,833,750...13,865,046
JBrowse link
G Mgll monoglyceride lipase decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of MGLL mRNA
Pravastatin affects the expression of MGLL mRNA
CTD PMID:27225895 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Miox myo-inositol oxygenase decreases expression ISO Pravastatin results in decreased expression of MIOX mRNA CTD PMID:27225895 NCBI chr 7:120,405,031...120,407,529
Ensembl chr 7:120,405,031...120,407,537
JBrowse link
G Mis18a MIS18 kinetochore protein A increases expression
decreases expression
ISO
EXP
Pravastatin results in increased expression of MIS18A mRNA
Pravastatin results in decreased expression of MIS18A mRNA
CTD PMID:27225895 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
JBrowse link
G Mlycd malonyl-CoA decarboxylase decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of MLYCD mRNA
Pravastatin affects the expression of MLYCD mRNA
CTD PMID:27225895 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Mme membrane metallo-endopeptidase affects expression
decreases expression
EXP
ISO
Pravastatin affects the expression of MME mRNA
Pravastatin results in decreased expression of MME mRNA
CTD PMID:27225895 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP Pravastatin results in decreased expression of MMP14 mRNA CTD PMID:16935385 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
decreases expression
EXP Pravastatin results in decreased activity of MMP2 protein
Pravastatin results in decreased expression of MMP2 mRNA
CTD PMID:16935385 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 affects response to substance ISO MMP3 promoter polymorphism affects the susceptibility to Pravastatin CTD PMID:8662692 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
decreases expression
EXP Pravastatin results in decreased activity of MMP9 protein
Pravastatin results in decreased expression of MMP9 mRNA
CTD PMID:16935385 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mss51 MSS51 mitochondrial translational activator decreases expression
increases expression
EXP
ISO
Pravastatin results in decreased expression of MSS51 mRNA
Pravastatin results in increased expression of MSS51 mRNA
CTD PMID:27225895 NCBI chr15:3,805,240...3,819,385
Ensembl chr15:3,807,516...3,819,385
JBrowse link
G Mstn myostatin increases expression ISO Pravastatin results in increased expression of MSTN protein CTD PMID:33034787 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Pravastatin results in increased phosphorylation of MTOR protein CTD PMID:15625077 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP
ISO
Pravastatin results in increased expression of MVD mRNA CTD PMID:27225895 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression EXP
ISO
Pravastatin results in increased expression of NFE2 mRNA CTD PMID:27225895 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression
decreases expression
ISO
EXP
Pravastatin results in increased expression of NNMT mRNA
Pravastatin results in increased expression of NNMT protein
Pravastatin results in decreased expression of NNMT mRNA
CTD PMID:27225895 PMID:33073877 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Pravastatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA] CTD PMID:18323514 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases phosphorylation
EXP [Resveratrol co-treated with Pravastatin] results in increased phosphorylation of NOS3 protein; Pravastatin promotes the reaction [NOS3 protein binds to NOS3 protein]; Pravastatin promotes the reaction [olmesartan results in increased activity of and results in increased phosphorylation of NOS3 protein]; Pravastatin results in increased activity of and results in increased phosphorylation of NOS3 protein
Pravastatin results in increased phosphorylation of NOS3 protein
CTD PMID:17170375 PMID:17188708 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO
EXP
Pravastatin results in decreased expression of NR0B2 mRNA CTD PMID:27225895 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression EXP
ISO
Pravastatin results in increased expression of NSDHL mRNA CTD PMID:27225895 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Pravastatin results in increased expression of OLR1 mRNA CTD PMID:27225895 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Orc1 origin recognition complex, subunit 1 affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of ORC1 mRNA
Pravastatin results in decreased expression of ORC1 mRNA
CTD PMID:27225895 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G P2ry10b P2Y receptor family member 10B affects expression ISO
EXP
Pravastatin affects the expression of P2RY10B mRNA CTD PMID:27225895 NCBI chr  X:72,255,526...72,281,013
Ensembl chr  X:72,238,713...72,281,012
JBrowse link
G Pcdhb5 protocadherin beta 5 increases expression EXP
ISO
Pravastatin results in increased expression of PCDHB4 mRNA CTD PMID:27225895 NCBI chr18:29,024,315...29,032,183
Ensembl chr18:29,028,382...29,053,259
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression EXP
ISO
Pravastatin results in increased expression of PCSK9 mRNA CTD PMID:27225895 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression ISO Pravastatin results in decreased expression of PCTP mRNA CTD PMID:27225895 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pde4a phosphodiesterase 4A decreases expression
increases expression
ISO
EXP
Pravastatin results in decreased expression of PDE4A mRNA
Pravastatin results in increased expression of PDE4A mRNA
CTD PMID:27225895 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of PDK4 mRNA
Pravastatin results in increased expression of PDK4 mRNA
CTD PMID:27225895 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression EXP
ISO
Pravastatin results in decreased expression of PEMT mRNA CTD PMID:27225895 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha decreases expression EXP
ISO
Pravastatin results in decreased expression of PEX11A mRNA CTD PMID:27225895 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP
ISO
Pravastatin results in decreased expression of PF4 mRNA CTD PMID:27225895 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 increases expression EXP
ISO
Pravastatin results in increased expression of PLA2R1 mRNA CTD PMID:27225895 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660
JBrowse link
G Plppr1 phospholipid phosphatase related 1 decreases expression ISO
EXP
Pravastatin results in decreased expression of PLPPR1 mRNA CTD PMID:27225895 NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
JBrowse link
G Pmvk phosphomevalonate kinase increases expression EXP
ISO
Pravastatin results in increased expression of PMVK mRNA CTD PMID:27225895 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 decreases expression EXP
ISO
Pravastatin results in decreased expression of PNPLA7 mRNA CTD PMID:27225895 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of POLE2 mRNA
Pravastatin results in decreased expression of POLE2 mRNA
CTD PMID:27225895 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
multiple interactions
affects localization
ISO
EXP
Pravastatin results in increased expression of PPARA protein
Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]
Pravastatin affects the localization of PPARA protein
[[Pravastatin co-treated with pirinixic acid] co-treated with [RXRA protein co-treated with PPARA protein]] results in increased expression of HMOX1 mRNA; [Pravastatin co-treated with [RXRA protein co-treated with PPARA protein]] results in increased expression of HMOX1 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Pravastatin affects the localization of PPARA protein]; Pravastatin promotes the reaction [PPARA protein binds to HMOX1 promoter]
CTD PMID:18812576 PMID:20368269 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Pravastatin inhibits the reaction [[troglitazone binds to and results in increased activity of PPARG protein] which results in increased abundance of Cholesterol] CTD PMID:12044893 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1j protein phosphatase, Mg2+/Mn2+ dependent, 1J decreases expression
increases expression
EXP
ISO
Pravastatin results in decreased expression of PPM1J mRNA
Pravastatin results in increased expression of PPM1J mRNA
CTD PMID:27225895 NCBI chr 2:192,278,597...192,283,883
Ensembl chr 2:192,278,517...192,283,882
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases activity ISO Pravastatin results in increased activity of PRKAA1 protein CTD PMID:33073877 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prnd prion like protein doppel decreases expression EXP
ISO
Pravastatin results in decreased expression of PRND mRNA CTD PMID:27225895 NCBI chr 3:119,213,462...119,218,742
Ensembl chr 3:119,213,429...119,218,745
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Pravastatin results in increased expression of PTGS2 protein CTD PMID:20368269 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N increases expression
affects expression
ISO
EXP
Pravastatin results in increased expression of PTPRN mRNA
Pravastatin affects the expression of PTPRN mRNA
CTD PMID:27225895 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Rdh11 retinol dehydrogenase 11 increases expression ISO
EXP
Pravastatin results in increased expression of RDH11 mRNA CTD PMID:27225895 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
JBrowse link
G Reep1 receptor accessory protein 1 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of REEP1 mRNA
Pravastatin results in increased expression of REEP1 mRNA
CTD PMID:27225895 NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338
JBrowse link
G Retsat retinol saturase decreases expression EXP
ISO
Pravastatin results in decreased expression of RETSAT mRNA CTD PMID:27225895 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
JBrowse link
G Rgs16 regulator of G-protein signaling 16 decreases expression EXP
ISO
Pravastatin results in decreased expression of RGS16 mRNA CTD PMID:27225895 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rnf186 ring finger protein 186 decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of RNF186 mRNA
Pravastatin affects the expression of RNF186 mRNA
CTD PMID:27225895 NCBI chr 5:151,210,492...151,211,716
Ensembl chr 5:151,210,492...151,211,716
JBrowse link
G Rragd Ras-related GTP binding D decreases expression ISO Pravastatin results in decreased expression of RRAGD mRNA CTD PMID:27225895 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions EXP [[Pravastatin co-treated with pirinixic acid] co-treated with [RXRA protein co-treated with PPARA protein]] results in increased expression of HMOX1 mRNA; [Pravastatin co-treated with [RXRA protein co-treated with PPARA protein]] results in increased expression of HMOX1 mRNA CTD PMID:20368269 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G S100a4 S100 calcium-binding protein A4 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of S100A4 mRNA
Pravastatin results in increased expression of S100A4 mRNA
CTD PMID:27225895 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100g S100 calcium binding protein G decreases expression ISO
EXP
Pravastatin results in decreased expression of S100G mRNA CTD PMID:27225895 NCBI chr  X:31,705,853...31,708,422
Ensembl chr  X:31,705,866...31,708,433
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 decreases expression ISO
EXP
Pravastatin results in decreased expression of SAT2 mRNA CTD PMID:27225895 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP Pravastatin results in increased expression of SCD mRNA CTD PMID:27225895 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO Pravastatin results in increased expression of SCD2 mRNA CTD PMID:27225895 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Selp selectin P decreases expression ISO Pravastatin results in decreased expression of SELP protein CTD PMID:11189483 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO
EXP
Pravastatin results in decreased expression of SERPINB1A mRNA CTD PMID:27225895 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Pravastatin results in increased expression of SFRP1 mRNA CTD PMID:27225895 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Shisa4 shisa family member 4 increases expression EXP
ISO
Pravastatin results in increased expression of SHISA4 mRNA CTD PMID:27225895 NCBI chr13:46,799,735...46,803,816
Ensembl chr13:46,799,772...46,803,998
JBrowse link
G Sirt1 sirtuin 1 increases phosphorylation ISO Pravastatin results in increased phosphorylation of SIRT1 protein CTD PMID:33073877 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of SLC10A1 mRNA CTD PMID:27225895 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc13a3 solute carrier family 13 member 3 decreases expression ISO Pravastatin results in decreased expression of SLC13A3 mRNA CTD PMID:27225895 NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
JBrowse link
G Slc15a3 solute carrier family 15 member 3 decreases expression ISO
EXP
Pravastatin results in decreased expression of SLC15A3 mRNA CTD PMID:27225895 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157
JBrowse link
G Slc16a5 solute carrier family 16 member 5 decreases expression
affects expression
ISO
EXP
Pravastatin results in decreased expression of SLC16A5 mRNA
Pravastatin affects the expression of SLC16A5 mRNA
CTD PMID:27225895 NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338
JBrowse link
G Slc17a1 solute carrier family 17 member 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of SLC17A1 mRNA CTD PMID:27225895 NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
JBrowse link
G Slc17a3 solute carrier family 17 member 3 decreases expression ISO
EXP
Pravastatin results in decreased expression of SLC17A3 mRNA CTD PMID:27225895 NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256
JBrowse link
G Slc22a5 solute carrier family 22 member 5 affects expression
decreases expression
EXP
ISO
Pravastatin affects the expression of SLC22A5 mRNA
Pravastatin results in decreased expression of SLC22A5 mRNA
CTD PMID:27225895 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc23a1 solute carrier family 23 member 1 decreases expression ISO
EXP
Pravastatin results in decreased expression of SLC23A1 mRNA CTD PMID:27225895 NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
JBrowse link
G Slc25a20 solute carrier family 25 member 20 decreases expression ISO Pravastatin results in decreased expression of SLC25A20 mRNA CTD PMID:27225895 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc25a34 solute carrier family 25, member 34 affects expression EXP Pravastatin affects the expression of SLC25A34 mRNA CTD PMID:27225895 NCBI chr 5:153,932,081...153,936,854 JBrowse link
G Slc25a42 solute carrier family 25, member 42 decreases expression EXP
ISO
Pravastatin results in decreased expression of SLC25A42 mRNA CTD PMID:27225895 NCBI chr16:19,213,914...19,251,990
Ensembl chr16:19,213,950...19,237,025
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression EXP
ISO
Pravastatin results in decreased expression of SLC27A2 mRNA CTD PMID:27225895 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO
EXP
Pravastatin results in decreased expression of SLC2A4 mRNA CTD PMID:27225895 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression ISO
EXP
Pravastatin results in decreased expression of SLC34A2 mRNA CTD PMID:27225895 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
JBrowse link
G Slc9b2 solute carrier family 9 member B2 affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of SLC9B2 mRNA
Pravastatin results in increased expression of SLC9B2 mRNA
CTD PMID:27225895 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects transport
decreases expression
ISO
EXP
SLCO1A4 protein affects the transport of Pravastatin
Pravastatin results in decreased expression of SLCO1A4 protein
CTD PMID:19833843 PMID:24909372 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco1a5 solute carrier organic anion transporter family, member 1A5 increases expression
decreases expression
ISO
EXP
Pravastatin results in increased expression of SLCO1A5 mRNA
Pravastatin results in decreased expression of SLCO1A5 mRNA
CTD PMID:27225895 NCBI chr 4:175,172,390...175,254,598
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO Pravastatin inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Pravastatin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein] CTD PMID:21430235 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Pravastatin inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Pravastatin inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein] CTD PMID:21430235 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression EXP
ISO
Pravastatin results in increased expression of SLCO4A1 mRNA CTD PMID:27225895 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
JBrowse link
G Smim3 small integral membrane protein 3 increases expression ISO Pravastatin results in increased expression of SMIM3 mRNA CTD PMID:27225895 NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416
JBrowse link
G Snap25 synaptosome associated protein 25 multiple interactions ISO [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of SNAP25 protein CTD PMID:26875785 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression ISO Pravastatin results in increased expression of SOCS3 protein CTD PMID:19330073 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Spag5 sperm associated antigen 5 affects expression
decreases expression
ISO
EXP
Pravastatin affects the expression of SPAG5 mRNA
Pravastatin results in decreased expression of SPAG5 mRNA
CTD PMID:27225895 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Spic Spi-C transcription factor decreases expression
increases expression
EXP
ISO
Pravastatin results in decreased expression of SPIC mRNA
Pravastatin results in increased expression of SPIC mRNA
CTD PMID:27225895 NCBI chr 7:23,069,815...23,077,517
Ensembl chr 7:23,069,821...23,077,548
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO Pravastatin results in decreased expression of SRD5A2 mRNA CTD PMID:27225895 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 decreases expression EXP
ISO
Pravastatin results in decreased expression of ST8SIA3 mRNA CTD PMID:27225895 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 increases expression ISO
EXP
Pravastatin results in increased expression of STARD4 mRNA CTD PMID:27225895 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Pravastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein] CTD PMID:18323514 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO Pravastatin results in decreased phosphorylation of STAT3 protein CTD PMID:19330073 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stx1a syntaxin 1A multiple interactions ISO [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of STX1A protein CTD PMID:26875785 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A affects expression
decreases expression
EXP
ISO
Pravastatin affects the expression of SULT1C2 mRNA
Pravastatin results in decreased expression of SULT1C2 mRNA
CTD PMID:27225895 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases expression ISO Pravastatin results in decreased expression of SULT1E1 mRNA CTD PMID:27225895 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of SULT2A1 mRNA CTD PMID:27225895 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Tex12 testis expressed 12 decreases expression EXP
ISO
Pravastatin results in decreased expression of TEX12 mRNA CTD PMID:27225895 NCBI chr 8:50,908,161...50,913,202
Ensembl chr 8:50,909,052...50,913,217
JBrowse link
G Thbd thrombomodulin affects expression
increases expression
EXP
ISO
Pravastatin affects the expression of THBD mRNA
Pravastatin results in increased expression of THBD mRNA
CTD PMID:27225895 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression EXP Pravastatin results in decreased expression of TIMP1 mRNA CTD PMID:16935385 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression EXP Pravastatin results in decreased expression of TIMP2 mRNA CTD PMID:16935385 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tlcd4 TLC domain containing 4 decreases expression ISO Pravastatin results in decreased expression of TLCD4 mRNA CTD PMID:27225895 NCBI chr 2:209,284,873...209,360,156
Ensembl chr 2:209,289,732...209,341,353
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression EXP
ISO
Pravastatin results in increased expression of TM7SF2 mRNA CTD PMID:27225895 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
G Tmem139 transmembrane protein 139 increases expression
decreases expression
EXP
ISO
Pravastatin results in increased expression of TMEM139 mRNA
Pravastatin results in decreased expression of TMEM139 mRNA
CTD PMID:27225895 NCBI chr 4:71,147,072...71,149,151
Ensembl chr 4:71,146,724...71,167,399
JBrowse link
G Tmem164 transmembrane protein 164 decreases expression
increases expression
EXP
ISO
Pravastatin results in decreased expression of TMEM164 mRNA
Pravastatin results in increased expression of TMEM164 mRNA
CTD PMID:27225895 NCBI chr  X:106,288,019...106,448,642
Ensembl chr  X:106,289,371...106,448,640
JBrowse link
G Tmem205 transmembrane protein 205 decreases expression ISO
EXP
Pravastatin results in decreased expression of TMEM205 mRNA CTD PMID:27225895 NCBI chr 8:20,452,092...20,458,011
Ensembl chr 8:20,452,092...20,457,828
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Pravastatin inhibits the reaction [LEP gene mutant form results in increased expression of TNF mRNA]; Pravastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Pravastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased abundance of Nitric Oxide]; Pravastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]
Pravastatin results in increased expression of TNF mRNA
CTD PMID:17729120 PMID:18323514 PMID:27225895 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf18 TNF superfamily member 18 affects expression ISO
EXP
Pravastatin affects the expression of TNFSF18 mRNA CTD PMID:27225895 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression ISO Pravastatin results in increased expression of TNNT2 mRNA CTD PMID:27225895 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO
EXP
[Pravastatin results in increased phosphorylation of MDM2 protein] which results in increased degradation of TP53 protein; Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of TP53 protein]; Pravastatin inhibits the reaction [leptomycin B results in decreased degradation of TP53 protein]; Pravastatin inhibits the reaction [lopinavir-ritonavir drug combination results in increased expression of TP53 protein]; Pravastatin inhibits the reaction [Ritonavir results in increased expression of TP53 protein]
Pravastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]
CTD PMID:15625077 PMID:20650967 PMID:20884875 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tspan13 tetraspanin 13 increases expression EXP
ISO
Pravastatin results in increased expression of TSPAN13 mRNA CTD PMID:27225895 NCBI chr 6:52,738,748...52,765,503
Ensembl chr 6:52,738,758...52,765,547
JBrowse link
G Ttc41 tetratricopeptide repeat domain 41 decreases expression ISO Pravastatin results in decreased expression of TTC41 mRNA CTD PMID:27225895 NCBI chr 7:21,124,909...21,188,191
Ensembl chr 7:21,125,105...21,188,189
JBrowse link
G Tuba1a tubulin, alpha 1A increases expression EXP
ISO
Pravastatin results in increased expression of TUBA1A mRNA CTD PMID:27225895 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases expression ISO
EXP
Pravastatin results in decreased expression of UGT2B1 mRNA CTD PMID:27225895 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Uroc1 urocanate hydratase 1 decreases expression EXP
ISO
Pravastatin results in decreased expression of UROC1 mRNA CTD PMID:27225895 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 multiple interactions ISO [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in decreased expression of VAMP2 protein CTD PMID:26875785 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vnn1 vanin 1 decreases expression ISO Pravastatin results in decreased expression of VNN1 mRNA CTD PMID:27225895 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression
decreases expression
ISO
EXP
Pravastatin results in increased expression of ZC3H12A mRNA
Pravastatin results in decreased expression of ZC3H12A mRNA
CTD PMID:27225895 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
rebaudioside A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases expression ISO rebaudioside A results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:30883860 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO rebaudioside A results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO rebaudioside A results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO rebaudioside A results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO rebaudioside A results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cat catalase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 decreases expression ISO rebaudioside A results in decreased expression of CAV1 mRNA CTD PMID:31655124 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO rebaudioside A results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO rebaudioside A results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Edn1 endothelin 1 decreases expression ISO rebaudioside A results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression ISO rebaudioside A results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO rebaudioside A results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Faslg Fas ligand increases expression ISO rebaudioside A results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO rebaudioside A results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO rebaudioside A results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] CTD PMID:25554529 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Il10 interleukin 10 multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL10 protein] CTD PMID:30883860 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il6 interleukin 6 multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL6 protein] CTD PMID:30883860 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Insr insulin receptor multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO rebaudioside A results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO rebaudioside A results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of MMP13 protein] CTD PMID:30883860 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP2 protein] CTD PMID:30883860 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
ISO
EXP
rebaudioside A results in increased expression of MMP9 mRNA
rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP9 protein]
CTD PMID:30883860 PMID:31655124 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 protein] CTD PMID:30883860 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pf4 platelet factor 4 increases expression ISO rebaudioside A results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO rebaudioside A results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of RELA protein] CTD PMID:30883860 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sele selectin E decreases expression ISO rebaudioside A results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Smad7 SMAD family member 7 multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of SMAD7 protein] CTD PMID:30883860 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein] CTD PMID:30883860 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TNF protein] CTD PMID:30883860 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO rebaudioside A results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
resolvin D2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:21724996 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein] CTD PMID:21724996 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein] CTD PMID:21724996 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA] CTD PMID:21724996 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] CTD PMID:21724996 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein] CTD PMID:21724996 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:21724996 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA] CTD PMID:21724996 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21724996 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:21724996 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21724996 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein] CTD PMID:21724996 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:21724996 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA] CTD PMID:21724996 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
retinyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B increases expression ISO retinol acetate results in increased expression of ACVR2B mRNA CTD PMID:16772331 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
multiple interactions
ISO retinol acetate results in decreased expression of ADIPOQ mRNA
NR1I3 protein affects the reaction [retinol acetate results in decreased expression of ADIPOQ mRNA]
CTD PMID:31449830 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Alb albumin affects binding ISO retinol acetate binds to ALB protein CTD PMID:17217919 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apoe apolipoprotein E increases expression ISO retinol acetate results in increased expression of APOE mRNA CTD PMID:16772331 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member increases expression ISO retinol acetate results in increased expression of BCAR1 mRNA CTD PMID:16772331 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO retinol acetate results in increased expression of BMP4 mRNA CTD PMID:16772331 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression ISO retinol acetate results in increased expression of BMP7 mRNA CTD PMID:16772331 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Calm1 calmodulin 1 increases expression ISO retinol acetate results in increased expression of CALM1 mRNA CTD PMID:16772331 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Cbl Cbl proto-oncogene increases expression ISO retinol acetate results in increased expression of CBL mRNA CTD PMID:16772331 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO retinol acetate results in increased expression of CCNB2 mRNA CTD PMID:16772331 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO retinol acetate results in increased expression of CCND1 mRNA CTD PMID:16772331 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 increases expression ISO retinol acetate results in increased expression of CCNE1 mRNA CTD PMID:16772331 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd36 CD36 molecule decreases expression
multiple interactions
ISO retinol acetate results in decreased expression of CD36 mRNA
NR1I3 protein affects the reaction [retinol acetate results in decreased expression of CD36 mRNA]
CTD PMID:31449830 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cdx2 caudal type homeo box 2 increases expression ISO retinol acetate results in increased expression of CDX2 mRNA CTD PMID:16772331 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO retinol acetate results in increased expression of CKS2 mRNA CTD PMID:16772331 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Crk CRK proto-oncogene, adaptor protein increases expression ISO retinol acetate results in increased expression of CRK mRNA CTD PMID:16772331 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 increases expression ISO retinol acetate results in increased expression of CSNK2A1 mRNA CTD PMID:16772331 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Ctsb cathepsin B increases expression ISO retinol acetate results in increased expression of CTSB mRNA CTD PMID:16772331 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D increases expression ISO retinol acetate results in increased expression of CTSD mRNA CTD PMID:16772331 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO retinol acetate results in decreased expression of CYP1A1 mRNA CTD PMID:28123100 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 mRNA; [retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 protein; BMS453 inhibits the reaction [retinol acetate results in increased expression of CYP26A1 mRNA]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 mRNA]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 protein]; NR1I3 protein affects the reaction [retinol acetate results in increased expression of CYP26A1 mRNA] CTD PMID:16322074 PMID:31449830 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases expression
ISO [bisphenol A co-treated with retinol acetate] results in increased expression of CYP2B10 mRNA
retinol acetate results in decreased expression of CYP2B10 mRNA
CTD PMID:28123100 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA CTD PMID:28123100 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dcn decorin increases expression ISO retinol acetate results in increased expression of DCN mRNA CTD PMID:16772331 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Dlx3 distal-less homeobox 3 increases expression ISO retinol acetate results in increased expression of DLX3 mRNA CTD PMID:16772331 NCBI chr10:80,064,489...80,069,891
Ensembl chr10:80,064,489...80,069,872
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO retinol acetate results in increased expression of DNAJC3 mRNA CTD PMID:16772331 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G E2f3 E2F transcription factor 3 increases expression ISO retinol acetate results in increased expression of E2F3 mRNA CTD PMID:16772331 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein increases expression ISO retinol acetate results in increased expression of EI24 mRNA CTD PMID:16772331 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
JBrowse link
G Eng endoglin increases expression ISO retinol acetate results in increased expression of ENG mRNA CTD PMID:16772331 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO retinol acetate results in increased expression of ETS2 mRNA CTD PMID:16772331 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 increases expression ISO retinol acetate results in increased expression of EYA2 mRNA CTD PMID:16772331 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO retinol acetate results in increased expression of FGFR3 mRNA CTD PMID:16772331 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 multiple interactions
decreases expression
ISO [bisphenol A co-treated with retinol acetate] results in decreased expression of FMO3 mRNA
retinol acetate results in decreased expression of FMO3 mRNA
CTD PMID:28123100 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Foxg1 forkhead box G1 increases expression ISO retinol acetate results in increased expression of FOXG1 mRNA CTD PMID:16772331 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607
JBrowse link
G Frzb frizzled-related protein increases expression ISO retinol acetate results in increased expression of FRZB mRNA CTD PMID:16772331 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Fxn frataxin increases expression ISO retinol acetate results in increased expression of FXN mRNA CTD PMID:16772331 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G Fzd3 frizzled class receptor 3 increases expression ISO retinol acetate results in increased expression of FZD3 mRNA CTD PMID:16772331 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G Fzd6 frizzled class receptor 6 increases expression ISO retinol acetate results in increased expression of FZD6 mRNA CTD PMID:16772331 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO retinol acetate results in increased expression of GADD45A mRNA CTD PMID:16772331 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO retinol acetate results in increased expression of GAPDH mRNA CTD PMID:16772331 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression ISO retinol acetate results in increased expression of HES1 mRNA CTD PMID:16772331 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO retinol acetate results in increased expression of HPRT1 mRNA CTD PMID:16772331 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO retinol acetate results in increased expression of HSPA4L mRNA CTD PMID:16772331 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO retinol acetate results in increased expression of HSPH1 mRNA CTD PMID:16772331 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO retinol acetate results in increased expression of ID3 mRNA CTD PMID:16772331 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Il4 interleukin 4 increases expression ISO retinol acetate results in increased expression of IL4 protein CTD PMID:11444878 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 affects response to substance
increases expression
ISO IL5 protein affects the susceptibility to retinol acetate
retinol acetate results in increased expression of IL5 protein
CTD PMID:11444878 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il5ra interleukin 5 receptor subunit alpha affects response to substance ISO IL5RA protein affects the susceptibility to retinol acetate CTD PMID:11444878 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
JBrowse link
G Il6 interleukin 6 increases expression ISO retinol acetate results in increased expression of IL6 protein CTD PMID:11444878 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO retinol acetate results in increased expression of JUND mRNA CTD PMID:16772331 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kif1b kinesin family member 1B increases expression ISO retinol acetate results in increased expression of KIF1B mRNA CTD PMID:16772331 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Kl Klotho increases expression ISO retinol acetate results in increased expression of KL mRNA CTD PMID:16772331 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Lama5 laminin subunit alpha 5 increases expression ISO retinol acetate results in increased expression of LAMA5 mRNA CTD PMID:16772331 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
JBrowse link
G Laptm4a lysosomal protein transmembrane 4 alpha increases expression ISO retinol acetate results in increased expression of LAPTM4A mRNA CTD PMID:16772331 NCBI chr 6:31,719,287...31,737,023
Ensembl chr 6:31,718,976...31,737,020
JBrowse link
G Lifr LIF receptor subunit alpha increases expression ISO retinol acetate results in increased expression of LIFR mRNA CTD PMID:16772331 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
JBrowse link
G Lrat lecithin retinol acyltransferase multiple interactions ISO [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in decreased expression of CYP2C39 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP4A10 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of MGST1 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of UGT1A1 mRNA; retinol acetate inhibits the reaction [LRAT gene mutant form results in decreased susceptibility to Thioacetamide] CTD PMID:24614237 PMID:28123100 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Ltbr lymphotoxin beta receptor increases expression ISO retinol acetate results in increased expression of LTBR mRNA CTD PMID:16772331 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 increases expression ISO retinol acetate results in increased expression of MAP3K3 mRNA CTD PMID:16772331 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases expression ISO retinol acetate results in increased expression of MAPK14 mRNA CTD PMID:16772331 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression ISO retinol acetate results in increased expression of MAPKAPK2 mRNA CTD PMID:16772331 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO retinol acetate results in increased expression of MET mRNA CTD PMID:16772331 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression
multiple interactions
ISO retinol acetate results in increased expression of MGST1 mRNA
[LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of MGST1 mRNA
CTD PMID:28123100 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO retinol acetate results in increased expression of MMP2 mRNA CTD PMID:16772331 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Msx1 msh homeobox 1 increases expression ISO retinol acetate results in increased expression of MSX1 mRNA CTD PMID:16772331 NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Msx2 msh homeobox 2 increases expression ISO retinol acetate results in increased expression of MSX2 mRNA CTD PMID:16772331 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor increases expression ISO retinol acetate results in increased expression of MYCN mRNA CTD PMID:16772331 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Myo1b myosin Ib increases expression ISO retinol acetate results in increased expression of MYO1B mRNA CTD PMID:16772331 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO retinol acetate results in increased expression of NFKBIA mRNA CTD PMID:16772331 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nid1 nidogen 1 increases expression ISO retinol acetate results in increased expression of NID1 mRNA CTD PMID:16772331 NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267
JBrowse link
G Notch1 notch receptor 1 increases expression ISO retinol acetate results in increased expression of NOTCH1 mRNA CTD PMID:16772331 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch2 notch receptor 2 increases expression ISO retinol acetate results in increased expression of NOTCH2 mRNA CTD PMID:16772331 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 mRNA]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 protein]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of PPARG mRNA]; NR1I3 protein affects the reaction [retinol acetate results in decreased expression of ADIPOQ mRNA]; NR1I3 protein affects the reaction [retinol acetate results in decreased expression of CD36 mRNA]; NR1I3 protein affects the reaction [retinol acetate results in increased expression of CYP26A1 mRNA] CTD PMID:31449830 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression ISO retinol acetate results in increased expression of PEA15A mRNA CTD PMID:16772331 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO retinol acetate results in increased expression of PHGDH mRNA CTD PMID:16772331 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO retinol acetate results in increased expression of PIK3R1 mRNA CTD PMID:16772331 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of PPARG mRNA; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of PPARG mRNA] CTD PMID:31449830 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Psen2 presenilin 2 increases expression ISO retinol acetate results in increased expression of PSEN2 mRNA CTD PMID:16772331 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 increases expression ISO retinol acetate results in increased expression of PTPN13 mRNA CTD PMID:16772331 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563
JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO retinol acetate results in increased expression of RAD50 mRNA CTD PMID:16772331 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Rangap1 RAN GTPase activating protein 1 increases expression ISO retinol acetate results in increased expression of RANGAP1 mRNA CTD PMID:16772331 NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438
JBrowse link
G Rbp4 retinol binding protein 4 increases expression ISO retinol acetate results in increased expression of RBP4 protein CTD PMID:31449830 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 increases expression ISO retinol acetate results in increased expression of ROR1 mRNA CTD PMID:16772331 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO retinol acetate results in increased expression of RXRA mRNA CTD PMID:16772331 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Satb1 SATB homeobox 1 increases expression ISO retinol acetate results in increased expression of SATB1 mRNA CTD PMID:16772331 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
JBrowse link
G Sdc1 syndecan 1 increases expression ISO retinol acetate results in increased expression of SDC1 mRNA CTD PMID:16772331 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264
JBrowse link
G Sim2 SIM bHLH transcription factor 2 increases expression ISO retinol acetate results in increased expression of SIM2 mRNA CTD PMID:16772331 NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663
JBrowse link
G Smn1 survival of motor neuron 1, telomeric increases expression ISO retinol acetate results in increased expression of SMN1 mRNA CTD PMID:16772331 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060
JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression ISO retinol acetate results in increased expression of SNAI1 mRNA CTD PMID:16772331 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO retinol acetate results in increased expression of SNAI2 mRNA CTD PMID:16772331 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO retinol acetate results in increased expression of SQSTM1 mRNA CTD PMID:16772331 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tbx2 T-box transcription factor 2 increases expression ISO retinol acetate results in increased expression of TBX2 mRNA CTD PMID:16772331 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression ISO retinol acetate results in increased expression of TIMP3 mRNA CTD PMID:16772331 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase increases expression ISO retinol acetate results in increased expression of TYRO3 mRNA CTD PMID:16772331 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of UGT1A1 mRNA CTD PMID:28123100 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Wnt11 Wnt family member 11 increases expression ISO retinol acetate results in increased expression of WNT11 mRNA CTD PMID:16772331 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294
JBrowse link
G Wnt7b Wnt family member 7B increases expression ISO retinol acetate results in increased expression of WNT7B mRNA CTD PMID:16772331 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta increases expression ISO retinol acetate results in increased expression of YWHAZ mRNA CTD PMID:16772331 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
retinyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ereg epiregulin increases expression ISO palmitate increases expression of Ereg mRNA in myofibroblast cells RGD PMID:23805328 RGD:39457689 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
steviol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA] CTD PMID:25554529 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO steviol results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO steviol results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO steviol binds to and results in increased activity of AHR protein CTD PMID:28887089 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO steviol results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO steviol results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO steviol results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cat catalase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO steviol results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO steviol results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO steviol results in increased expression of CYP1A1 mRNA; steviol results in increased expression of CYP1A1 protein CTD PMID:28887089 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO steviol results in increased expression of CYP1A2 mRNA; steviol results in increased expression of CYP1A2 protein CTD PMID:28887089 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO steviol results in increased expression of CYP1B1 mRNA CTD PMID:28887089 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO steviol results in increased expression of CYP2B6 mRNA CTD PMID:28887089 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
ISO steviol results in increased expression of CYP3A4 mRNA; steviol results in increased expression of CYP3A4 protein
steviol binds to and results in decreased activity of CYP3A4 protein
CTD PMID:28887089 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Edn1 endothelin 1 decreases expression ISO steviol results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression ISO steviol results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO steviol results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Faslg Fas ligand increases expression ISO steviol results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA] CTD PMID:25554529 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO steviol results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO steviol results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] CTD PMID:25554529 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA] CTD PMID:25554529 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Insr insulin receptor multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO steviol results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO steviol results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PRKAA1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PRKAA1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO steviol results in increased expression of MMP9 mRNA CTD PMID:31655124 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO steviol binds to and results in increased activity of NR1I2 protein CTD PMID:28887089 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pf4 platelet factor 4 increases expression ISO steviol results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA] CTD PMID:25554529 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PRKAA1 mRNA] CTD PMID:25554529 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO steviol results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sele selectin E decreases expression ISO steviol results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO steviol results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
stevioside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases expression ISO stevioside results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP stevioside inhibits the reaction [Scopolamine results in increased activity of ACHE protein] CTD PMID:20871768 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases secretion EXP stevioside results in decreased secretion of ACP5 protein CTD PMID:21089163 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO stevioside results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO stevioside results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO stevioside results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO stevioside results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cat catalase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO stevioside results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO stevioside results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO stevioside results in increased expression of CYP1A1 mRNA CTD PMID:28887089 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO stevioside results in increased expression of CYP1A2 mRNA; stevioside results in increased expression of CYP1A2 protein CTD PMID:28887089 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO stevioside results in increased expression of CYP1B1 mRNA CTD PMID:28887089 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO stevioside binds to and results in decreased activity of CYP3A4 protein
stevioside results in increased expression of CYP3A4 mRNA; stevioside results in increased expression of CYP3A4 protein
CTD PMID:28887089 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Edn1 endothelin 1 decreases expression ISO stevioside results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression ISO stevioside results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO stevioside results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Faslg Fas ligand increases expression ISO stevioside results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO stevioside results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO stevioside results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] CTD PMID:25554529 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Insr insulin receptor multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO stevioside results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO stevioside results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO stevioside results in increased expression of MMP9 mRNA CTD PMID:31655124 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pf4 platelet factor 4 increases expression ISO stevioside results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA] CTD PMID:25554529 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO stevioside results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sele selectin E decreases expression ISO stevioside results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO stevioside results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19848
    chemical entity 19846
      atom 19846
        nonmetal atom 19784
          carbon atom 19737
            organic molecular entity 19737
              olefinic compound 16976
                allylic alcohol 969
                  drimendiol 0
                  primary allylic alcohol + 680
                  secondary allylic alcohol + 335
                  tertiary allylic alcohol + 80
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    p-block element atom 19796
                      chalcogen 19552
                        oxygen atom 19527
                          oxygen molecular entity 19527
                            hydroxides 19334
                              organic hydroxy compound 18967
                                alcohol 15705
                                  allylic alcohol 969
                                    drimendiol 0
                                    primary allylic alcohol + 680
                                    secondary allylic alcohol + 335
                                    tertiary allylic alcohol + 80
paths to the root