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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:81565
Term: resolvin D2
Definition: A member of the class of resolvins that is (4Z,8E,10Z,12E,14E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 7, 16 and 17 (the 7S,16R,17S-stereoisomer).
Chemical ID: MESH:C545423
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2multiple interactionsISORGD:7310076480464CTDresolvin D2 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]

PMID:21724996
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.