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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2998
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ldlr
Name: low density lipoprotein receptor
Acc ID: CHEBI:145024
Term: steviol
Definition: An ent-kaurane diterpenoid that is 5beta,8alpha,9beta,10alpha-kaur-16-en-18-oic acid in which the hydrogen at position 13 has been replaced by a hydroxy group.
Chemical ID: MESH:C012042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ldlrmultiple interactionsISORGD:108646480464CTDsteviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PRKAA1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA]

PMID:25554529
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