Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Clstn3 | Rat | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of CLSTN3 mRNA | CTD | PMID:30723492 | Clstn3 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:21394737 | Clstn3 | Rat | 2,2',5,5'-tetrachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | Clstn3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Clstn3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CLSTN3 mRNA | CTD | PMID:21570461 more ... | Clstn3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CLSTN3 mRNA | CTD | PMID:33387578 | Clstn3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CLSTN3 mRNA | CTD | PMID:32109520 | Clstn3 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Clstn3 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Clstn3 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CLSTN3 mRNA | CTD | PMID:20188158 | Clstn3 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CLSTN3 mRNA | CTD | PMID:24848799 | Clstn3 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of CLSTN3 mRNA | CTD | PMID:18648102 | Clstn3 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CLSTN3 mRNA | CTD | PMID:36041667 | Clstn3 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Clstn3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of CLSTN3 gene | CTD | PMID:31683443 | Clstn3 | Rat | 7,12-dimethyltetraphene | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | 9 more ... | CTD | PMID:32553695 | Clstn3 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of CLSTN3 mRNA | CTD | PMID:31881176 | Clstn3 | Rat | acrylamide | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of CLSTN3 mRNA | CTD | PMID:32763439 | Clstn3 | Rat | aldehydo-D-glucose | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLSTN3 mRNA | CTD | PMID:37567420 | Clstn3 | Rat | all-trans-retinoic acid | increases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of CLSTN3 mRNA | CTD | PMID:23724009 | Clstn3 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CLSTN3 mRNA | CTD | PMID:16483693 | Clstn3 | Rat | antirheumatic drug | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of CLSTN3 mRNA | CTD | PMID:24449571 | Clstn3 | Rat | aristolochic acid A | increases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of CLSTN3 mRNA | CTD | PMID:33212167 | Clstn3 | Rat | atrazine | increases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Atrazine results in increased expression of CLSTN3 mRNA | CTD | PMID:22378314 | Clstn3 | Rat | benzo[a]pyrene | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of CLSTN3 mRNA | CTD | PMID:20106945 and PMID:32234424 | Clstn3 | Rat | benzo[a]pyrene | decreases methylation | ISO | CLSTN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of CLSTN3 5' UTR and Benzo(a)pyrene results in decreased methylation of CLSTN3 promoter | CTD | PMID:27901495 | Clstn3 | Rat | benzo[a]pyrene | increases methylation | ISO | Clstn3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of CLSTN3 exon and Benzo(a)pyrene results in increased methylation of CLSTN3 intron | CTD | PMID:27901495 | Clstn3 | Rat | benzo[a]pyrene | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Benzo(a)pyrene metabolite results in decreased expression of CLSTN3 mRNA and Benzo(a)pyrene results in decreased expression of CLSTN3 mRNA | CTD | PMID:23735875 and PMID:32553695 | Clstn3 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA | CTD | PMID:31199487 | Clstn3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CLSTN3 mRNA | CTD | PMID:25181051 and PMID:34947998 | Clstn3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CLSTN3 mRNA | CTD | PMID:36041667 | Clstn3 | Rat | bisphenol A | increases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of CLSTN3 mRNA | CTD | PMID:32028606 | Clstn3 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of CLSTN3 gene | CTD | PMID:28505145 | Clstn3 | Rat | bisphenol A | increases methylation | ISO | Clstn3 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of CLSTN3 promoter | CTD | PMID:27312807 | Clstn3 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CLSTN3 mRNA | CTD | PMID:36041667 | Clstn3 | Rat | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of CLSTN3 mRNA | CTD | PMID:32479839 | Clstn3 | Rat | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA | CTD | PMID:31199487 | Clstn3 | Rat | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of CLSTN3 promoter | CTD | PMID:22457795 | Clstn3 | Rat | carbon nanotube | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of CLSTN3 mRNA | CTD | PMID:25554681 | Clstn3 | Rat | carbon nanotube | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of CLSTN3 mRNA | CTD | PMID:25620056 | Clstn3 | Rat | CGP 52608 | multiple interactions | ISO | CLSTN3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CLSTN3 gene] | CTD | PMID:28238834 | Clstn3 | Rat | clofibrate | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Clofibrate results in increased expression of CLSTN3 mRNA | CTD | PMID:23811191 and PMID:30629241 | Clstn3 | Rat | copper atom | multiple interactions | ISO | CLSTN3 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of CLSTN3 mRNA | CTD | PMID:31162603 | Clstn3 | Rat | copper(0) | multiple interactions | ISO | CLSTN3 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of CLSTN3 mRNA | CTD | PMID:31162603 | Clstn3 | Rat | copper(II) chloride | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | cupric chloride results in decreased expression of CLSTN3 mRNA | CTD | PMID:38568856 | Clstn3 | Rat | D-glucose | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLSTN3 mRNA | CTD | PMID:37567420 | Clstn3 | Rat | dexamethasone | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of CLSTN3 mRNA | CTD | PMID:25047013 | Clstn3 | Rat | dexamethasone | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CLSTN3 mRNA | CTD | PMID:24848799 | Clstn3 | Rat | dibenz[a,h]anthracene | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | Clstn3 | Rat | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA | CTD | PMID:31199487 | Clstn3 | Rat | dichloroacetic acid | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of CLSTN3 mRNA | CTD | PMID:28962523 | Clstn3 | Rat | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA | CTD | PMID:31199487 | Clstn3 | Rat | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA | CTD | PMID:31199487 | Clstn3 | Rat | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA | CTD | PMID:31199487 | Clstn3 | Rat | ethanol | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Ethanol results in increased expression of CLSTN3 mRNA | CTD | PMID:30319688 | Clstn3 | Rat | ethanol | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of CLSTN3 mRNA | CTD | PMID:30319688 | Clstn3 | Rat | fenamidone | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | fenamidone results in decreased expression of CLSTN3 mRNA | CTD | PMID:27029645 | Clstn3 | Rat | fructose | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLSTN3 mRNA | CTD | PMID:37567420 | Clstn3 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CLSTN3 mRNA | CTD | PMID:33387578 | Clstn3 | Rat | glucose | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLSTN3 mRNA | CTD | PMID:37567420 | Clstn3 | Rat | inulin | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CLSTN3 mRNA | CTD | PMID:36331819 | Clstn3 | Rat | isotretinoin | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of CLSTN3 mRNA | CTD | PMID:20436886 | Clstn3 | Rat | lead(0) | affects expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Lead affects the expression of CLSTN3 mRNA | CTD | PMID:28903495 | Clstn3 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of CLSTN3 mRNA | CTD | PMID:22401849 | Clstn3 | Rat | monosodium L-glutamate | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CLSTN3 mRNA | CTD | PMID:19001666 | Clstn3 | Rat | niclosamide | increases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of CLSTN3 mRNA | CTD | PMID:36318118 | Clstn3 | Rat | paracetamol | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of CLSTN3 mRNA | CTD | PMID:29067470 | Clstn3 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CLSTN3 mRNA | CTD | PMID:33387578 | Clstn3 | Rat | pentachlorophenol | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of CLSTN3 mRNA | CTD | PMID:23892564 | Clstn3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CLSTN3 mRNA | CTD | PMID:36331819 | Clstn3 | Rat | permethrin | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Permethrin results in increased expression of CLSTN3 mRNA | CTD | PMID:30629241 | Clstn3 | Rat | pioglitazone | multiple interactions | ISO | Clstn3 (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLSTN3 mRNA | CTD | PMID:27935865 | Clstn3 | Rat | pirinixic acid | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of CLSTN3 mRNA | CTD | PMID:18301758 more ... | Clstn3 | Rat | pravastatin | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Pravastatin results in decreased expression of CLSTN3 mRNA | CTD | PMID:27225895 | Clstn3 | Rat | pravastatin | affects expression | EXP | | 6480464 | Pravastatin affects the expression of CLSTN3 mRNA | CTD | PMID:27225895 | Clstn3 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of CLSTN3 mRNA | CTD | PMID:28903501 | Clstn3 | Rat | selenomethionine | affects expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Selenomethionine affects the expression of CLSTN3 mRNA | CTD | PMID:17222674 | Clstn3 | Rat | silver atom | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Silver results in increased expression of CLSTN3 mRNA | CTD | PMID:27131904 | Clstn3 | Rat | silver(0) | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Silver results in increased expression of CLSTN3 mRNA | CTD | PMID:27131904 | Clstn3 | Rat | sodium arsenite | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CLSTN3 mRNA | CTD | PMID:38568856 | Clstn3 | Rat | sodium arsenite | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of CLSTN3 mRNA | CTD | PMID:37682722 | Clstn3 | Rat | sunitinib | decreases expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of CLSTN3 mRNA | CTD | PMID:31533062 | Clstn3 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of CLSTN3 mRNA | CTD | PMID:30723492 | Clstn3 | Rat | titanium dioxide | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of CLSTN3 mRNA | CTD | PMID:23557971 | Clstn3 | Rat | tributylstannane | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | tributyltin results in increased expression of CLSTN3 mRNA | CTD | PMID:24848799 | Clstn3 | Rat | trichloroethene | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of CLSTN3 mRNA | CTD | PMID:25549359 | Clstn3 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CLSTN3 mRNA | CTD | PMID:33387578 | Clstn3 | Rat | triptonide | decreases expression | ISO | Clstn3 (Mus musculus) | 6480464 | triptonide results in decreased expression of CLSTN3 mRNA | CTD | PMID:33045310 | Clstn3 | Rat | troglitazone | increases expression | ISO | Clstn3 (Mus musculus) | 6480464 | troglitazone results in increased expression of CLSTN3 mRNA | CTD | PMID:28973697 | Clstn3 | Rat | uranium atom | affects expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Uranium affects the expression of CLSTN3 mRNA | CTD | PMID:15672453 | Clstn3 | Rat | valproic acid | affects expression | ISO | CLSTN3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CLSTN3 mRNA | CTD | PMID:25979313 | Clstn3 | Rat | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of CLSTN3 promoter | CTD | PMID:33150595 | Clstn3 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of CLSTN3 mRNA | CTD | PMID:33150595 | Clstn3 | Rat | zaragozic acid A | affects expression | ISO | Clstn3 (Mus musculus) | 6480464 | squalestatin 1 affects the expression of CLSTN3 mRNA | CTD | PMID:27225895 | Clstn3 | Rat | zaragozic acid A | increases expression | EXP | | 6480464 | squalestatin 1 results in increased expression of CLSTN3 mRNA | CTD | PMID:27225895 | |