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Gene: Rfx5 (regulatory factor X5) Rattus norvegicus
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Symbol: Rfx5
Name: regulatory factor X5
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in MHC class II deficiency and severe combined immunodeficiency. Orthologous to human RFX5 (regulatory factor X5); PARTICIPATES IN antigen processing and presentation pathway; primary immunodeficiency pathway; tuberculosis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA-binding protein RFX5; regulator factor X 5; regulatory factor X, 5 (influences HLA class II expression)
Orthologs:
Homo sapiens (human) : RFX5 (regulatory factor X5)  HGNC  Alliance
Mus musculus (house mouse) : Rfx5 (regulatory factor X, 5 (influences HLA class II expression))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfx5 (regulatory factor X5)
Pan paniscus (bonobo/pygmy chimpanzee) : RFX5 (regulatory factor X5)
Canis lupus familiaris (dog) : RFX5 (regulatory factor X5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfx5 (regulatory factor X5)
Sus scrofa (pig) : RFX5 (regulatory factor X5)
Chlorocebus sabaeus (African green monkey) : RFX5 (regulatory factor X5)
Heterocephalus glaber (naked mole-rat) : Rfx5 (regulatory factor X5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02196,119,054 - 196,128,109 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,120,580 - 196,128,095 (+)Ensembl
Rnor_5.02215,615,220 - 215,622,795 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,855,438 - 189,862,953 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12189,815,436 - 189,820,045 (+)NCBI
Celera2175,063,246 - 175,070,761 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rfx5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311677
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.