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Gene: Foxo4 (forkhead box O4) Rattus norvegicus
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Symbol: Foxo4
Name: forkhead box O4
Description: Exhibits promoter-specific chromatin binding activity. Involved in several processes, including aging; positive regulation of smooth muscle cell migration; and response to water-immersion restraint stress. Localizes to the cytosol and nucleus. Biomarker of alcohol-induced mental disorder; gastric ulcer; and paraplegia. Orthologous to human FOXO4 (forkhead box O4); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (+)-schisandrin B; acrylamide; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: forkhead box protein O4; LOC302415; RGD1561201; similar to forkhead protein AFXH
Orthologs:
Homo sapiens (human) : FOXO4 (forkhead box O4)  HGNC  Alliance
Mus musculus (house mouse) : Foxo4 (forkhead box O4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxo4 (forkhead box O4)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXO4 (forkhead box O4)
Canis lupus familiaris (dog) : FOXO4 (forkhead box O4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxo4 (forkhead box O4)
Sus scrofa (pig) : FOXO4 (forkhead box O4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X71,155,284 - 71,162,158 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X72,007,762 - 72,014,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,332,278 - 89,338,835 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX66,741,475 - 66,748,019 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Foxo4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561201
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.