Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621163
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mif
Name: macrophage migration inhibitory factor
Acc ID: CHEBI:63749
Term: (+)-artemisinic acid
Definition: A monocarboxylic acid that is prop-2-enoic acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). It is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua.
Chemical ID: MESH:C047721
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mifdecreases expressionISORGD:7342036480464CTDartemisic acid results in decreased expression of MIF mRNA

PMID:23063590
Go Back to source page   Continue to Ontology report