Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Nrgn (neurogranin) Rattus norvegicus
Analyze
Symbol: Nrgn
Name: neurogranin
Description: Exhibits calmodulin binding activity; phosphatidic acid binding activity; and phosphatidylinositol-3,4,5-trisphosphate binding activity. Involved in associative learning; modulation of chemical synaptic transmission; and telencephalon development. Localizes to several cellular components, including the cytoplasm; neuron projection; and postsynaptic density. Biomarker of hypothyroidism and visual epilepsy. Orthologous to human NRGN (neurogranin); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,4-dithiothreitol; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BICKS; neurogranin (protein kinase C substrate RC3); neurogranin (protein kinase C substrate, RC3); ng; protein kinase C substrate 7.5 kDa protein; RC3
Orthologs:
Homo sapiens (human) : NRGN (neurogranin)  HGNC  Alliance
Mus musculus (house mouse) : Nrgn (neurogranin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrgn (neurogranin)
Pan paniscus (bonobo/pygmy chimpanzee) : NRGN (neurogranin)
Canis lupus familiaris (dog) : NRGN (neurogranin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrgn (neurogranin)
Sus scrofa (pig) : NRGN (neurogranin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0840,015,049 - 40,023,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0840,015,873 - 40,024,017 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,790,596 - 38,799,077 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1838,799,361 - 38,807,843 (-)NCBI
Celera837,191,658 - 37,199,870 (+)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nrgn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61833
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.