 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Bodner SM, etal., Gene 1999 Mar 18;229(1-2):223-8. |
| 2. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | GOA data from the GO Consortium |
| 4. | MGD Curation, June 12, 2002 |
| 5. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 6. | RGD automated data pipeline |
| 7. | RGD automated import pipeline for gene-chemical interactions |
| 8. | Walentinsson A, etal., Cancer Res 2001 Nov 15;61(22):8263-73. |
| 9. | Walentinsson A, etal., Mamm Genome 2001 Dec;12(12):900-8. |
References - uncuratedGenomics
Comparative Map Data| Dmtf1 (Rattus norvegicus - Norway rat) |
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| DMTF1 (Homo sapiens - human) |
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| Dmtf1 (Mus musculus - house mouse) |
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| Dmtf1 (Chinchilla lanigera - long-tailed chinchilla) |
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| DMTF1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DMTF1 (Canis lupus familiaris - dog) |
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| Dmtf1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DMTF1 (Sus scrofa - pig) |
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| DMTF1 (Chlorocebus sabaeus - African green monkey) |
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| Dmtf1 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| RH137636 |
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| RH138123 |
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| RH139646 |
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| RH140676 |
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| RH141561 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 40 | 46 | 30 | 19 | 30 | 5 | 5 | 74 | 35 | 38 | 11 | 5 |
| Low | 3 | 11 | 11 | 11 | 3 | 6 | 3 | 3 | |||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_053693 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017592381 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07059494 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01028045 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01028046 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF352169 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF352170 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF352171 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC081880 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000007948 ⟹ ENSRNOP00000007948 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000044810 ⟹ ENSRNOP00000046030 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_053693 ⟹ NP_446145 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GGCGCGGCCGTGGCTCCGTTTCCGGTGGCTGGTTGCGCTCGCTCACCCCAGCTGCAGCCACTCThide sequence |
| RefSeq Acc Id: | XM_017592381 ⟹ XP_017447870 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GAGAGGGCGGGGGCGGGGCGCGGCCGTGGCTCCGTTTCCGGTGGCTGGTTGCGCTCGCTCACCChide sequence |
Protein Sequences| Protein RefSeqs | NP_446145 | (Get FASTA) | NCBI Sequence Viewer |
| XP_017447870 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAH81880 | (Get FASTA) | NCBI Sequence Viewer |
| AAK32705 | (Get FASTA) | NCBI Sequence Viewer | |
| AAK32706 | (Get FASTA) | NCBI Sequence Viewer | |
| AAK32707 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL84309 | (Get FASTA) | NCBI Sequence Viewer | |
| Q66HG1 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_446145 ⟸ NM_053693 |
| - UniProtKB: | Q66HG1 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEIDSEDSTEPPHKRLCLSSEDDQSIhide sequence |
| RefSeq Acc Id: | XP_017447870 ⟸ XM_017592381 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HG1 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEIDSEDSTEPPHKRLCLSSEDDQSIhide sequence |
| RefSeq Acc Id: | ENSRNOP00000046030 ⟸ ENSRNOT00000044810 |
| RefSeq Acc Id: | ENSRNOP00000007948 ⟸ ENSRNOT00000007948 |
Protein Domains
HTH myb-type Myb-like
TranscriptomePromoters| RGD ID: | 13692824 | ||||||||
| Promoter ID: | EPDNEW_R3349 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Dmtf1_1 | ||||||||
| Description: | cyclin D binding myb-like transcription factor 1 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: Rnor_5.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 4 | 21820231 | 21820232 | C | T | snv | IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU) |
| 4 | 21825270 | 21825271 | C | T | snv | IS-Tlk/Kyo (KyushuU) |
Assembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 4 | 21371264 | 21371265 | C | T | snv | DA/BklArbNsi (ICAHN) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:70966 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000005908 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000007948 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOP00000046030 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| Ensembl Transcript | ENSRNOT00000007948 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOT00000044810 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| IMAGE_CLONE | IMAGE:7108159 | IMAGE-MGC_LOAD |
| InterPro | Homeobox-like_sf | UniProtKB/Swiss-Prot |
| Myb-like_dom | UniProtKB/Swiss-Prot | |
| Myb_dom | UniProtKB/Swiss-Prot | |
| SANT/Myb | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:114485 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:93746 | IMAGE-MGC_LOAD |
| NCBI Gene | 114485 | ENTREZGENE |
| Pfam | Myb_DNA-binding | UniProtKB/Swiss-Prot |
| PhenoGen | Dmtf1 | PhenoGen |
| PROSITE | HTH_MYB | UniProtKB/Swiss-Prot |
| MYB_LIKE | UniProtKB/Swiss-Prot | |
| SMART | SANT | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF46689 | UniProtKB/Swiss-Prot |
| UniGene | Rn.116028 | ENTREZGENE |
| UniProt | DMTF1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
| UniProt Secondary | Q99MC8 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2002-07-09 | Dmtf1 | cyclin D binding myb-like transcription factor 1 | Symbol and Name updated to reflect Human and Mouse nomenclature | 70877 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_disease | upregulated in uterine tumors | 70348 |
| gene_disease | upregulated in uterine tumors | 70557 |
| gene_expression | expressed in uterus | 70348 |
| gene_expression | expressed in uterus | 70557 |
| gene_mapping | maps to a region of chromosome 4 which is commonly amplified in endometrial adenocarcinomas in BDII/Han rats | 70557 |
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| More on Dmtf1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 70966 |
| Created: | 2002-07-09 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
