Hmbox1 (homeobox containing 1) - Rat Genome Database

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Gene: Hmbox1 (homeobox containing 1) Rattus norvegicus
Analyze
Symbol: Hmbox1
Name: homeobox containing 1
RGD ID: 1306787
Description: Predicted to enable double-stranded telomeric DNA binding activity; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of telomere maintenance via telomerase. Predicted to be located in several cellular components, including centrosome; chromosome, telomeric region; and nuclear body. Predicted to be active in nucleus. Orthologous to human HMBOX1 (homeobox containing 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeobox-containing protein 1; LOC305968; RGD1306787; similar to hypothetical protein FLJ21616
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81543,243,503 - 43,376,011 (-)NCBIGRCr8
mRatBN7.21539,067,805 - 39,200,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1539,067,804 - 39,200,323 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01548,194,709 - 48,326,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1548,199,995 - 48,284,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01551,919,925 - 52,073,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41544,182,450 - 44,305,484 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11544,197,983 - 44,320,631 (-)NCBI
Celera1538,744,265 - 38,876,101 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA,ISO)
chromosome, telomeric region  (ISO)
cytoplasm  (ISO)
cytosol  (IEA,ISO)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19135898   PMID:19757162   PMID:20822188   PMID:21839858   PMID:23332764   PMID:23685356   PMID:25416956   PMID:28473536  


Genomics

Comparative Map Data
Hmbox1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81543,243,503 - 43,376,011 (-)NCBIGRCr8
mRatBN7.21539,067,805 - 39,200,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1539,067,804 - 39,200,323 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01548,194,709 - 48,326,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1548,199,995 - 48,284,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01551,919,925 - 52,073,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41544,182,450 - 44,305,484 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11544,197,983 - 44,320,631 (-)NCBI
Celera1538,744,265 - 38,876,101 (-)NCBICelera
Cytogenetic Map15p12NCBI
HMBOX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38828,890,116 - 29,053,270 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl828,890,395 - 29,064,764 (+)EnsemblGRCh38hg38GRCh38
GRCh37828,747,912 - 28,910,787 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36828,804,144 - 28,965,351 (+)NCBINCBI36Build 36hg18NCBI36
Celera827,707,732 - 27,869,989 (+)NCBICelera
Cytogenetic Map8p21.1-p12NCBI
HuRef827,293,007 - 27,455,132 (+)NCBIHuRef
CHM1_1828,949,910 - 29,112,203 (+)NCBICHM1_1
T2T-CHM13v2.0829,168,300 - 29,331,436 (+)NCBIT2T-CHM13v2.0
Hmbox1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391465,049,049 - 65,187,354 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1465,049,049 - 65,187,320 (-)EnsemblGRCm39 Ensembl
GRCm381464,811,600 - 64,949,899 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1464,811,600 - 64,949,871 (-)EnsemblGRCm38mm10GRCm38
MGSCv371465,441,055 - 65,568,684 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361463,776,328 - 63,903,957 (-)NCBIMGSCv36mm8
Celera1462,584,174 - 62,711,763 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.79NCBI
Hmbox1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540351,257,472 - 51,365,835 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBIChiLan1.0ChiLan1.0
HMBOX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2747,434,897 - 47,612,451 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1823,147,878 - 23,325,337 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0828,173,256 - 28,350,591 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1825,370,077 - 25,547,208 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl825,446,264 - 25,547,208 (+)Ensemblpanpan1.1panPan2
HMBOX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12528,489,472 - 28,679,322 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2528,489,506 - 28,679,748 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2529,137,090 - 29,327,184 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02528,643,730 - 28,835,028 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2528,643,730 - 28,835,023 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12528,603,599 - 28,794,841 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02528,491,031 - 28,680,245 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02528,653,266 - 28,842,626 (-)NCBIUU_Cfam_GSD_1.0
Hmbox1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049436,844,865 - 7,007,445 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366751,647,143 - 1,735,390 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366751,578,705 - 1,741,283 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMBOX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1412,692,588 - 12,882,558 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11412,692,607 - 12,895,078 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21413,933,447 - 14,137,116 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HMBOX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1826,999,474 - 27,177,244 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl826,999,468 - 27,163,526 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605214,947,485 - 15,131,238 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hmbox1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475823,548,514 - 23,638,713 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475823,472,719 - 23,649,924 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hmbox1
530 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:108
Interacting mature miRNAs:119
Transcripts:ENSRNOT00000017962, ENSRNOT00000038288, ENSRNOT00000038336, ENSRNOT00000059102
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat

Markers in Region
RH144424  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21539,078,728 - 39,078,893 (+)MAPPERmRatBN7.2
Rnor_6.01548,205,630 - 48,205,794NCBIRnor6.0
Rnor_5.01551,952,852 - 51,953,016UniSTSRnor5.0
RGSC_v3.41544,183,099 - 44,183,263UniSTSRGSC3.4
Celera1538,755,183 - 38,755,347UniSTS
RH 3.4 Map15289.9UniSTS
Cytogenetic Map15p12UniSTS
BF398724  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21539,085,069 - 39,085,294 (+)MAPPERmRatBN7.2
Rnor_6.01548,211,971 - 48,212,195NCBIRnor6.0
Rnor_5.01551,959,193 - 51,959,417UniSTSRnor5.0
RGSC_v3.41544,189,440 - 44,189,664UniSTSRGSC3.4
Celera1538,761,524 - 38,761,748UniSTS
RH 3.4 Map15290.5UniSTS
Cytogenetic Map15p12UniSTS
BF391108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21539,143,525 - 39,143,669 (+)MAPPERmRatBN7.2
Rnor_6.01548,269,517 - 48,269,660NCBIRnor6.0
Rnor_5.01552,016,426 - 52,016,569UniSTSRnor5.0
RGSC_v3.41544,248,718 - 44,248,861UniSTSRGSC3.4
Celera1538,819,997 - 38,820,140UniSTS
RH 3.4 Map15289.9UniSTS
Cytogenetic Map15p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 31 30 14 18 14 2 2 74 35 38 11 2
Low 2 12 27 27 1 27 6 9 3 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000038336   ⟹   ENSRNOP00000029528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1539,081,326 - 39,200,323 (-)Ensembl
Rnor_6.0 Ensembl1548,199,995 - 48,284,548 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109493   ⟹   ENSRNOP00000085503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1539,068,584 - 39,200,323 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112734   ⟹   ENSRNOP00000077167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1539,068,584 - 39,200,323 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000120015   ⟹   ENSRNOP00000092747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1539,067,804 - 39,200,323 (-)Ensembl
RefSeq Acc Id: NM_001427100   ⟹   NP_001414029
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,507 - 43,376,011 (-)NCBI
RefSeq Acc Id: NM_001427101   ⟹   NP_001414030
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,507 - 43,376,011 (-)NCBI
RefSeq Acc Id: XM_039094008   ⟹   XP_038949936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,809 - 39,200,350 (-)NCBI
RefSeq Acc Id: XM_039094009   ⟹   XP_038949937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,809 - 39,200,352 (-)NCBI
RefSeq Acc Id: XM_039094010   ⟹   XP_038949938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,809 - 39,200,353 (-)NCBI
RefSeq Acc Id: XM_039094013   ⟹   XP_038949941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,809 - 39,200,341 (-)NCBI
RefSeq Acc Id: XM_039094014   ⟹   XP_038949942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,255,130 - 43,375,874 (-)NCBI
mRatBN7.21539,079,439 - 39,200,346 (-)NCBI
RefSeq Acc Id: XM_039094015   ⟹   XP_038949943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,255,130 - 43,375,874 (-)NCBI
mRatBN7.21539,079,439 - 39,200,348 (-)NCBI
RefSeq Acc Id: XM_039094016   ⟹   XP_038949944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,805 - 39,200,343 (-)NCBI
RefSeq Acc Id: XM_039094017   ⟹   XP_038949945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,805 - 39,200,345 (-)NCBI
RefSeq Acc Id: XM_039094018   ⟹   XP_038949946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,805 - 39,200,345 (-)NCBI
RefSeq Acc Id: XM_039094019   ⟹   XP_038949947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,255,130 - 43,375,874 (-)NCBI
mRatBN7.21539,079,439 - 39,200,349 (-)NCBI
RefSeq Acc Id: XM_039094020   ⟹   XP_038949948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,805 - 39,200,345 (-)NCBI
RefSeq Acc Id: XM_039094021   ⟹   XP_038949949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,874 (-)NCBI
mRatBN7.21539,067,805 - 39,200,346 (-)NCBI
RefSeq Acc Id: XM_063274287   ⟹   XP_063130357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81543,243,503 - 43,375,257 (-)NCBI
RefSeq Acc Id: ENSRNOP00000029528   ⟸   ENSRNOT00000038336
RefSeq Acc Id: XP_038949949   ⟸   XM_039094021
- Peptide Label: isoform X11
- UniProtKB: D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949948   ⟸   XM_039094020
- Peptide Label: isoform X10
- UniProtKB: D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949946   ⟸   XM_039094018
- Peptide Label: isoform X8
- UniProtKB: A0A8I5Y5F7 (UniProtKB/TrEMBL),   D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949945   ⟸   XM_039094017
- Peptide Label: isoform X8
- UniProtKB: A0A8I5Y5F7 (UniProtKB/TrEMBL),   D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949944   ⟸   XM_039094016
- Peptide Label: isoform X8
- UniProtKB: A0A8I5Y5F7 (UniProtKB/TrEMBL),   D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949938   ⟸   XM_039094010
- Peptide Label: isoform X3
- UniProtKB: A6K6I6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949937   ⟸   XM_039094009
- Peptide Label: isoform X2
- UniProtKB: A6K6I6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949936   ⟸   XM_039094008
- Peptide Label: isoform X1
- UniProtKB: A6K6I6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949941   ⟸   XM_039094013
- Peptide Label: isoform X5
- UniProtKB: A6K6I6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949947   ⟸   XM_039094019
- Peptide Label: isoform X9
- UniProtKB: D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949943   ⟸   XM_039094015
- Peptide Label: isoform X7
- UniProtKB: D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949942   ⟸   XM_039094014
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A3H7 (UniProtKB/TrEMBL),   A6K6I7 (UniProtKB/TrEMBL),   D3ZER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000085503   ⟸   ENSRNOT00000109493
RefSeq Acc Id: ENSRNOP00000092747   ⟸   ENSRNOT00000120015
RefSeq Acc Id: ENSRNOP00000077167   ⟸   ENSRNOT00000112734
RefSeq Acc Id: XP_063130357   ⟸   XM_063274287
- Peptide Label: isoform X4
RefSeq Acc Id: NP_001414029   ⟸   NM_001427100
- Peptide Label: isoform 2
- UniProtKB: A6K6I6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414030   ⟸   NM_001427101
- Peptide Label: isoform 1
- UniProtKB: A0A8I6GJY0 (UniProtKB/TrEMBL),   A6K6I6 (UniProtKB/TrEMBL)
Protein Domains
HNF-p1   Homeobox   POU-specific atypical

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZER1-F1-model_v2 AlphaFold D3ZER1 1-404 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306787 AgrOrtholog
BioCyc Gene G2FUF-13370 BioCyc
Ensembl Genes ENSRNOG00000013326 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038336.7 UniProtKB/TrEMBL
  ENSRNOT00000109493.1 UniProtKB/TrEMBL
  ENSRNOT00000112734.1 UniProtKB/TrEMBL
  ENSRNOT00000120015.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.260.40 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Cro/C1-type_HTH UniProtKB/TrEMBL
  HMBOX1 UniProtKB/TrEMBL
  HNF-1_N UniProtKB/TrEMBL
  HNF-1_POU UniProtKB/TrEMBL
  HNF_P1 UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  Lambda_DNA-bd UniProtKB/TrEMBL
NCBI Gene 305968 ENTREZGENE
PANTHER HOMEOBOX-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR14618 UniProtKB/TrEMBL
Pfam HNF-1_N UniProtKB/TrEMBL
  Homeobox UniProtKB/TrEMBL
PhenoGen Hmbox1 PhenoGen
PROSITE HNF_P1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  POU_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013326 RatGTEx
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
  Lambda_like_DNA UniProtKB/TrEMBL
UniProt A0A8I5Y5F7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A3H7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJY0 ENTREZGENE, UniProtKB/TrEMBL
  A6K6I6 ENTREZGENE, UniProtKB/TrEMBL
  A6K6I7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZER1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Hmbox1  homeobox containing 1  RGD1306787_predicted  similar to hypothetical protein FLJ21616 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1306787_predicted  similar to hypothetical protein FLJ21616 (predicted)  LOC305968_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305968_predicted  similar to hypothetical protein FLJ21616 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL