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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1583230
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rarg
Name: retinoic acid receptor, gamma
Acc ID: CHEBI:17336
Term: all-trans-retinol
Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rargmultiple interactionsISORarg (Mus musculus)6480464CTDRARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA]PMID:16397886
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