Hrg (histidine-rich glycoprotein) - Rat Genome Database

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Pathways
Gene: Hrg (histidine-rich glycoprotein) Rattus norvegicus
Analyze
Symbol: Hrg (Ensembl: Hrgl1)
Name: histidine-rich glycoprotein (Ensembl:histidine-rich glycoprotein like 1)
RGD ID: 619808
Description: Predicted to enable several functions, including heme binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Predicted to be involved in several processes, including negative regulation of endothelial cell migration; negative regulation of fibrinolysis; and negative regulation of lamellipodium assembly. Predicted to be located in cell surface. Predicted to be active in extracellular region. Human ortholog(s) of this gene implicated in thrombophilia due to HRG deficiency and thrombosis. Orthologous to human HRG (histidine rich glycoprotein); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: histidine-proline-rich glycoprotein; histidine-rich glycoprotein 1; HPRG; HRG1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,559,087 - 91,573,982 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1191,559,091 - 91,573,982 (-)EnsemblGRCr8
mRatBN7.21178,054,488 - 78,069,402 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1178,054,498 - 78,069,389 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1186,804,961 - 86,819,853 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,463,216 - 79,478,058 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,519,273 - 78,534,165 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,621,274 - 81,639,938 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,621,283 - 81,639,952 (-)Ensemblrn6Rnor6.0
Rnor_5.01184,718,226 - 84,736,651 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41180,248,578 - 80,264,179 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1176,927,058 - 76,941,902 (-)NCBICelera
RGSC_v3.11180,306,169 - 80,321,768 (-)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chlorotoluron  (ISO)
clofibrate  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
diarsenic trioxide  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
fructose  (ISO)
furan  (EXP)
gentamycin  (EXP)
glucose  (ISO)
glycidol  (ISO)
graphite  (EXP)
GW 4064  (ISO)
heparin  (ISO)
irinotecan  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
Mesaconitine  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
olanzapine  (ISO)
ouabain  (ISO)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pravastatin  (EXP,ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
Triptolide  (EXP,ISO)
troglitazone  (ISO)
ursodeoxycholic acid  (EXP)
valproic acid  (EXP,ISO)
zaragozic acid A  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (ISO)
extracellular region  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Murine histidine-rich glycoprotein: cloning, characterization and cellular origin. Hulett MD and Parish CR, Immunol Cell Biol 2000 Jun;78(3):280-7.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Identification of potential prognostic biomarkers in patients with untreated, advanced pancreatic cancer from a phase 3 trial (Cancer and Leukemia Group B 80303). Roberts AS, etal., Cancer. 2012 Jan 15;118(2):571-8. doi: 10.1002/cncr.26270. Epub 2011 Jun 28.
12. HRG Tokushima: molecular and cellular characterization of histidine-rich glycoprotein (HRG) deficiency. Shigekiyo T, etal., Blood. 1998 Jan 1;91(1):128-33.
13. Heregulin, cysteine rich-61 and matrix metalloproteinase 9 expression in human carotid atherosclerotic plaques: relationship with clinical data. Sigala F, etal., Eur J Vasc Endovasc Surg. 2006 Sep;32(3):238-45. doi: 10.1016/j.ejvs.2006.01.026. Epub 2006 Jun 13.
Additional References at PubMed
PMID:678554   PMID:6740558   PMID:10514432   PMID:12477932   PMID:14744774   PMID:15138272   PMID:15220341   PMID:15869579   PMID:16436387   PMID:16489009   PMID:18797515   PMID:19056867  
PMID:19903770   PMID:21215706   PMID:21264222   PMID:21304106   PMID:22348394   PMID:22516433   PMID:23376485   PMID:23395172   PMID:23533145   PMID:27068509   PMID:31880188  


Genomics

Comparative Map Data
Hrg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,559,087 - 91,573,982 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1191,559,091 - 91,573,982 (-)EnsemblGRCr8
mRatBN7.21178,054,488 - 78,069,402 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1178,054,498 - 78,069,389 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1186,804,961 - 86,819,853 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,463,216 - 79,478,058 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,519,273 - 78,534,165 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,621,274 - 81,639,938 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,621,283 - 81,639,952 (-)Ensemblrn6Rnor6.0
Rnor_5.01184,718,226 - 84,736,651 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41180,248,578 - 80,264,179 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1176,927,058 - 76,941,902 (-)NCBICelera
RGSC_v3.11180,306,169 - 80,321,768 (-)NCBI
Cytogenetic Map11q23NCBI
HRG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,666,014 - 186,678,234 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,660,216 - 186,678,234 (+)Ensemblhg38GRCh38
GRCh373186,383,803 - 186,396,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,866,492 - 187,878,717 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343187,866,499 - 187,878,724NCBI
Celera3184,820,230 - 184,832,456 (+)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,793,470 - 183,805,692 (+)NCBIHuRef
CHM1_13186,347,752 - 186,359,974 (+)NCBICHM1_1
T2T-CHM13v2.03189,487,766 - 189,499,996 (+)NCBIT2T-CHM13v2.0
Hrg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,769,822 - 22,780,409 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,769,822 - 22,780,406 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381622,951,072 - 22,961,659 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1622,951,072 - 22,961,656 (+)Ensemblmm10GRCm38
MGSCv371622,951,145 - 22,961,732 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361622,866,448 - 22,876,980 (+)NCBIMGSCv36mm8
Celera1623,511,005 - 23,521,593 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.79NCBI
Hrg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542021,019,212 - 21,032,976 (-)Ensembl
ChiLan1.0NW_00495542021,020,938 - 21,033,022 (-)NCBIChiLan1.0ChiLan1.0
HRG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22184,541,834 - 184,554,072 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13184,546,549 - 184,558,787 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03183,701,069 - 183,712,365 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13192,168,299 - 192,180,539 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,168,299 - 192,180,539 (+)EnsemblpanPan2panpan1.1
HRG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,276,487 - 19,286,540 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,276,549 - 19,286,537 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3423,361,891 - 23,371,917 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03419,187,471 - 19,197,522 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,187,509 - 19,197,783 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13419,219,778 - 19,229,696 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03419,219,621 - 19,229,772 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03419,448,102 - 19,458,128 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hrg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,193,744 - 117,204,015 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365783,285,986 - 3,295,876 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365783,285,986 - 3,295,876 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HRG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,505,312 - 124,516,705 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113124,505,305 - 124,516,387 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,895,233 - 133,906,338 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HRG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1152,753,819 - 2,766,946 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl152,753,810 - 2,766,478 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606311,490,597 - 11,503,244 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hrg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473070,070,302 - 70,086,256 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:55
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000047595
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)119046178196556255Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
RH130910  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,054,621 - 78,054,822 (+)MAPPERmRatBN7.2
Rnor_6.01181,621,402 - 81,621,602NCBIRnor6.0
Rnor_5.01184,718,354 - 84,718,554UniSTSRnor5.0
RGSC_v3.41180,248,706 - 80,248,906UniSTSRGSC3.4
RGSC_v3.41180,230,715 - 80,230,915UniSTSRGSC3.4
Celera1176,927,186 - 76,927,386UniSTS
Celera1176,912,075 - 76,912,275UniSTS
RH 3.4 Map11642.2UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 30 57 57 41 21 41 155 40 22 66 29 16

Sequence


Ensembl Acc Id: ENSRNOT00000047595   ⟹   ENSRNOP00000049290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1181,621,346 - 81,639,872 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081864   ⟹   ENSRNOP00000072623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1178,054,498 - 78,069,389 (-)Ensembl
Rnor_6.0 Ensembl1181,621,283 - 81,639,952 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090031   ⟹   ENSRNOP00000075182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1181,621,325 - 81,639,876 (-)Ensembl
RefSeq Acc Id: NM_133428   ⟹   NP_596919
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81191,559,087 - 91,573,982 (-)NCBI
mRatBN7.21178,054,494 - 78,069,389 (-)NCBI
Rnor_6.01181,621,274 - 81,639,923 (-)NCBI
Rnor_5.01184,718,226 - 84,736,651 (-)NCBI
RGSC_v3.41180,248,578 - 80,264,179 (-)RGD
Celera1176,927,058 - 76,941,902 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_596919 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89779 (Get FASTA)   NCBI Sequence Viewer  
  BAB33092 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072623
GenBank Protein Q99PS8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_596919   ⟸   NM_133428
- Peptide Label: precursor
- UniProtKB: Q99PS7 (UniProtKB/Swiss-Prot),   D3ZJN0 (UniProtKB/Swiss-Prot),   Q9ESB2 (UniProtKB/Swiss-Prot),   Q99PS8 (UniProtKB/Swiss-Prot),   A0A0G2K3G0 (UniProtKB/TrEMBL),   A6JS43 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075182   ⟸   ENSRNOT00000090031
Ensembl Acc Id: ENSRNOP00000049290   ⟸   ENSRNOT00000047595
Ensembl Acc Id: ENSRNOP00000072623   ⟸   ENSRNOT00000081864
Protein Domains
Cystatin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99PS8-F1-model_v2 AlphaFold Q99PS8 1-525 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698250
Promoter ID:EPDNEW_R8773
Type:multiple initiation site
Name:Hrg_1
Description:histidine-rich glycoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01181,639,923 - 81,639,983EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619808 AgrOrtholog
BioCyc Gene G2FUF-20831 BioCyc
Ensembl Genes ENSRNOG00000001809 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000081864 ENTREZGENE
Gene3D-CATH 3.10.450.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7371893 IMAGE-MGC_LOAD
InterPro Cystatin_dom UniProtKB/Swiss-Prot
  Cystatin_sf UniProtKB/Swiss-Prot
  Kininogen_Fetuin_HRG UniProtKB/Swiss-Prot
KEGG Report rno:171016 UniProtKB/Swiss-Prot
  rno:681544 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108609 IMAGE-MGC_LOAD
NCBI Gene 171016 ENTREZGENE
PANTHER FETUIN UniProtKB/Swiss-Prot
  HISTIDINE-RICH GLYCOPROTEIN UniProtKB/Swiss-Prot
PhenoGen Hrg PhenoGen
RatGTEx ENSRNOG00000001809 RatGTEx
SMART SM00043 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54403 UniProtKB/Swiss-Prot
UniProt A0A0G2K3G0 ENTREZGENE, UniProtKB/TrEMBL
  A6JS43 ENTREZGENE, UniProtKB/TrEMBL
  D3ZJN0 ENTREZGENE
  HRG_RAT UniProtKB/Swiss-Prot
  Q99PS7 ENTREZGENE
  Q99PS8 ENTREZGENE
  Q9ESB2 ENTREZGENE
UniProt Secondary D3ZJN0 UniProtKB/Swiss-Prot
  Q99PS7 UniProtKB/Swiss-Prot
  Q9ESB2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Hrg  histidine-rich glycoprotein      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Hrg  histidine-rich glycoprotein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein contains 510 amino acids 632990