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Gene: Hrg (histidine-rich glycoprotein) Rattus norvegicus
Symbol: Hrg
Name: histidine-rich glycoprotein
RGD ID: 619808
Description: Predicted to have several functions, including anion binding activity; heme binding activity; and serine-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including defense response to other organism; negative regulation of endothelial cell migration; and regulation of blood coagulation. Predicted to localize to cell surface; extracellular region; and lysosome. Human ortholog(s) of this gene implicated in thrombophilia due to HRG deficiency and thrombosis. Orthologous to human HRG (histidine rich glycoprotein); INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: histidine-proline-rich glycoprotein; histidine-rich glycoprotein 1; HPRG; HRG1
Homo sapiens (human) : HRG (histidine rich glycoprotein)  HGNC  Alliance
Mus musculus (house mouse) : Hrg (histidine-rich glycoprotein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hrg (histidine rich glycoprotein)
Pan paniscus (bonobo/pygmy chimpanzee) : HRG (histidine rich glycoprotein)
Canis lupus familiaris (dog) : HRG (histidine rich glycoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hrg (histidine rich glycoprotein)
Sus scrofa (pig) : HRG (histidine rich glycoprotein)
Chlorocebus sabaeus (African green monkey) : HRG (histidine rich glycoprotein)
Heterocephalus glaber (naked mole-rat) : Hrg (histidine rich glycoprotein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01181,621,274 - 81,639,938 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,621,283 - 81,639,952 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01184,718,226 - 84,736,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,248,578 - 80,264,179 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,306,169 - 80,321,768 (-)NCBI
Celera1176,927,058 - 76,941,902 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hrg
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619808
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.