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Gene: Hrg (histidine-rich glycoprotein) Rattus norvegicus
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Symbol: Hrg
Name: histidine-rich glycoprotein
Description: Predicted to have several functions, including anion binding activity; heme binding activity; and serine-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including negative regulation of endothelial cell migration; regulation of blood coagulation; and regulation of cellular protein metabolic process. Predicted to localize to the cell surface; extracellular region; and lysosome. Human ortholog(s) of this gene implicated in thrombophilia and thrombosis. Orthologous to human HRG (histidine rich glycoprotein); INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: histidine-proline-rich glycoprotein; histidine-rich glycoprotein 1; HPRG; HRG1
Orthologs:
Homo sapiens (human) : HRG (histidine rich glycoprotein)  HGNC  Alliance
Mus musculus (house mouse) : Hrg (histidine-rich glycoprotein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hrg (histidine rich glycoprotein)
Pan paniscus (bonobo/pygmy chimpanzee) : HRG (histidine rich glycoprotein)
Canis lupus familiaris (dog) : HRG (histidine rich glycoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hrg (histidine rich glycoprotein)
Sus scrofa (pig) : HRG (histidine rich glycoprotein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01181,621,274 - 81,639,938 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,621,283 - 81,639,952 (-)Ensembl
Rnor_5.01184,718,226 - 84,736,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,248,578 - 80,264,179 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,306,169 - 80,321,768 (-)NCBI
Celera1176,927,058 - 76,941,902 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hrg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619808
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.