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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:16605
Term: allyl alcohol
Definition: A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds.
Chemical ID: MESH:C006463
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1increases expressionEXP 6480464CTDallyl alcohol results in increased expression of TGFB1 mRNAPMID:11063159 PMID:18564211
Tgfb1multiple interactionsEXP 6480464CTDTamoxifen inhibits the reaction [allyl alcohol results in increased expression of TGFB1 mRNA]PMID:18564211
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