Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Atp4a (ATPase H+/K+ transporting subunit alpha) Rattus norvegicus
Symbol: Atp4a
Name: ATPase H+/K+ transporting subunit alpha
Description: Predicted to have potassium:proton exchanging ATPase activity; protein heterodimerization activity; and sodium:potassium-exchanging ATPase activity. Predicted to be involved in several processes, including inorganic cation transmembrane transport; monovalent inorganic cation homeostasis; and regulation of proton transport. Localizes to apical plasma membrane. Orthologous to human ATP4A (ATPase H+/K+ transporting subunit alpha); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATPase H+/K+ transporting alpha subunit; ATPase H+K+-transporting alpha / (gastric HK-ATPase catalytic subunit); ATPase, H+,K+-transporting, alpha / (gastric H,K-ATPase catalytic subunit); ATPase, H+/K+ exchanging, alpha polypeptide; ATPase, H+/K+ transporting, alpha polypeptide; gastric H(+)/K(+) ATPase subunit alpha; gastric H,K-ATPase catalytic subunit; H+,K+-ATPase alpha subunit; Hka; HKATPC; hydrogen/potassium-exchanging ATPase 4A; potassium-transporting ATPase alpha chain 1; proton pump; RATHKATPC
Homo sapiens (human) : ATP4A (ATPase H+/K+ transporting subunit alpha)  HGNC  Alliance
Mus musculus (house mouse) : Atp4a (ATPase, H+/K+ exchanging, gastric, alpha polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp4a (ATPase H+/K+ transporting subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Canis lupus familiaris (dog) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp4a (ATPase H+/K+ transporting subunit alpha)
Sus scrofa (pig) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Chlorocebus sabaeus (African green monkey) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Heterocephalus glaber (naked mole-rat) : Atp4a (ATPase H+/K+ transporting subunit alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0189,162,700 - 89,175,504 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,162,639 - 89,175,811 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,317,629 - 90,330,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,756,388 - 85,769,192 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.152,286,438 - 2,286,714 (+)NCBI
Celera180,333,302 - 80,346,109 (+)NCBICelera
Cytogenetic Map1q21NCBI
RH 2.0 Map1561.1RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atp4a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2177
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.