Elavl2 (ELAV like RNA binding protein 2) - Rat Genome Database

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Gene: Elavl2 (ELAV like RNA binding protein 2) Rattus norvegicus
Analyze
Symbol: Elavl2
Name: ELAV like RNA binding protein 2
RGD ID: 628611
Description: Predicted to enable RNA binding activity. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be part of ribonucleoprotein complex. Predicted to be active in synapse. Orthologous to human ELAVL2 (ELAV like RNA binding protein 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); ELAV like neuron-specific RNA binding protein 2; ELAV-like protein 2; Elav2; embryonic lethal, abnormal vision-like 2; hu-antigen B; Hub; LOC360404; RNA binding protein HuB
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25105,960,872 - 106,086,539 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl5105,960,875 - 106,109,097 (-)Ensembl
Rnor_6.05109,499,410 - 109,651,829 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5109,499,408 - 109,651,730 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05113,450,847 - 113,601,141 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45111,178,875 - 111,304,980 (-)NCBIRGSC3.4rn4RGSC3.4
Celera5104,638,371 - 104,764,344 (-)NCBICelera
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:8889548   PMID:17534028   PMID:19115409   PMID:20439489   PMID:21139978   PMID:22658674   PMID:22681889   PMID:22871113   PMID:28252024   PMID:29476059   PMID:31696225  


Genomics

Comparative Map Data
Elavl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25105,960,872 - 106,086,539 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl5105,960,875 - 106,109,097 (-)Ensembl
Rnor_6.05109,499,410 - 109,651,829 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5109,499,408 - 109,651,730 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05113,450,847 - 113,601,141 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45111,178,875 - 111,304,980 (-)NCBIRGSC3.4rn4RGSC3.4
Celera5104,638,371 - 104,764,344 (-)NCBICelera
Cytogenetic Map5q32NCBI
ELAVL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38923,690,104 - 23,850,601 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl923,690,104 - 23,826,337 (-)EnsemblGRCh38hg38GRCh38
GRCh37923,690,102 - 23,850,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36923,680,102 - 23,816,063 (-)NCBINCBI36hg18NCBI36
Build 34923,681,983 - 23,816,301NCBI
Celera923,612,711 - 23,748,673 (-)NCBI
Cytogenetic Map9p21.3NCBI
HuRef923,638,458 - 23,774,406 (-)NCBIHuRef
CHM1_1923,689,866 - 23,825,861 (-)NCBICHM1_1
T2T-CHM13v2.0923,696,100 - 23,856,586 (-)NCBI
Elavl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39491,099,770 - 91,288,407 (-)NCBIGRCm39mm39
GRCm39 Ensembl491,139,000 - 91,289,022 (-)Ensembl
GRCm38491,211,533 - 91,400,108 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl491,250,763 - 91,400,785 (-)EnsemblGRCm38mm10GRCm38
MGSCv37490,917,457 - 91,066,675 (-)NCBIGRCm37mm9NCBIm37
MGSCv36490,742,784 - 90,892,002 (-)NCBImm8
Celera489,703,358 - 89,852,432 (-)NCBICelera
Cytogenetic Map4C5NCBI
cM Map442.36NCBI
Elavl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547210,549,986 - 10,710,774 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547210,550,138 - 10,710,756 (+)NCBIChiLan1.0ChiLan1.0
ELAVL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1924,155,627 - 24,315,255 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl924,155,627 - 24,230,254 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0923,543,090 - 23,703,634 (-)NCBIMhudiblu_PPA_v0panPan3
ELAVL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11142,504,205 - 42,647,093 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1142,506,381 - 42,671,284 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1141,182,601 - 41,325,292 (-)NCBI
ROS_Cfam_1.01143,444,501 - 43,587,493 (-)NCBI
ROS_Cfam_1.0 Ensembl1143,444,233 - 43,587,479 (-)Ensembl
UMICH_Zoey_3.11142,116,176 - 42,258,890 (-)NCBI
UNSW_CanFamBas_1.01142,004,575 - 42,147,332 (-)NCBI
UU_Cfam_GSD_1.01142,750,401 - 42,893,306 (-)NCBI
Elavl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947157,354,147 - 157,507,805 (-)NCBI
SpeTri2.0NW_004936827878,632 - 1,002,034 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELAVL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1198,964,132 - 199,135,811 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11198,964,070 - 199,135,815 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21222,013,128 - 222,092,572 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Elavl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473627,692,201 - 27,882,787 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473627,554,445 - 27,884,382 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
U29088  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.05113,453,643 - 113,453,794NCBIRnor5.0
RGSC_v3.45111,181,108 - 111,181,258UniSTSRGSC3.4
Celera5104,640,604 - 104,640,754UniSTS
Cytogenetic Map5q32UniSTS
PMC337033P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25105,962,737 - 105,962,962 (+)MAPPERmRatBN7.2
mRatBN7.25105,962,787 - 105,962,962 (+)MAPPERmRatBN7.2
mRatBN7.25105,962,737 - 105,963,351 (+)MAPPERmRatBN7.2
Rnor_6.05109,501,276 - 109,502,064NCBIRnor6.0
Rnor_6.05109,501,276 - 109,501,500NCBIRnor6.0
Rnor_5.05113,452,713 - 113,453,501UniSTSRnor5.0
Rnor_5.05113,452,713 - 113,452,937UniSTSRnor5.0
RGSC_v3.45111,180,741 - 111,180,965UniSTSRGSC3.4
Celera5104,640,237 - 104,640,461UniSTS
Cytogenetic Map5q32UniSTS
Elavl4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25105,962,376 - 105,962,535 (+)MAPPERmRatBN7.2
Rnor_6.05109,500,915 - 109,501,073NCBIRnor6.0
Rnor_5.05113,452,352 - 113,452,510UniSTSRnor5.0
RGSC_v3.45111,180,380 - 111,180,538UniSTSRGSC3.4
Celera5104,639,876 - 104,640,034UniSTS
Cytogenetic Map5q32UniSTS
ELAVL2__7577  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25105,962,550 - 105,963,498 (+)MAPPERmRatBN7.2
Rnor_6.05109,501,089 - 109,502,600NCBIRnor6.0
Rnor_5.05113,452,526 - 113,454,037UniSTSRnor5.0
RGSC_v3.45111,180,554 - 111,181,501UniSTSRGSC3.4
Celera5104,640,050 - 104,640,997UniSTS
Cytogenetic Map5q32UniSTS
Elavl2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25105,962,786 - 105,963,428 (+)MAPPERmRatBN7.2
mRatBN7.25105,962,958 - 105,963,428 (+)MAPPERmRatBN7.2
Rnor_6.05109,501,497 - 109,502,530NCBIRnor6.0
Rnor_6.05109,502,061 - 109,502,530NCBIRnor6.0
Rnor_5.05113,453,498 - 113,453,967UniSTSRnor5.0
Rnor_5.05113,452,934 - 113,453,967UniSTSRnor5.0
RGSC_v3.45111,180,962 - 111,181,431UniSTSRGSC3.4
Celera5104,640,458 - 104,640,927UniSTS
Cytogenetic Map5q32UniSTS
Elavl2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25105,963,428 - 105,963,494 (+)MAPPERmRatBN7.2
Rnor_6.05109,502,531 - 109,502,596NCBIRnor6.0
Rnor_5.05113,453,968 - 113,454,033UniSTSRnor5.0
RGSC_v3.45111,181,432 - 111,181,497UniSTSRGSC3.4
Celera5104,640,928 - 104,640,993UniSTS
Cytogenetic Map5q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599753548113061097Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:397
Count of miRNA genes:217
Interacting mature miRNAs:291
Transcripts:ENSRNOT00000009034
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 72 11
Low 16 9 6 6 2 12 27 9
Below cutoff 2 24 22 10 7 10 7 7 11 3 1 7

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001302217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB098713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI145457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000009034   ⟹   ENSRNOP00000009034
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5105,960,875 - 106,086,463 (-)Ensembl
Rnor_6.0 Ensembl5109,499,408 - 109,625,723 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092743   ⟹   ENSRNOP00000075983
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5105,962,304 - 106,021,807 (-)Ensembl
Rnor_6.0 Ensembl5109,499,408 - 109,621,317 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093007   ⟹   ENSRNOP00000076072
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5109,530,877 - 109,621,170 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093032   ⟹   ENSRNOP00000076021
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5105,960,875 - 106,109,097 (-)Ensembl
Rnor_6.0 Ensembl5109,499,707 - 109,651,730 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105492   ⟹   ENSRNOP00000094592
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5105,962,304 - 106,086,463 (-)Ensembl
RefSeq Acc Id: NM_001302217   ⟹   NP_001289146
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25105,960,872 - 106,086,539 (-)NCBI
Rnor_6.05109,499,410 - 109,625,799 (-)NCBI
Celera5104,638,371 - 104,764,344 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001289146 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAC53775 (Get FASTA)   NCBI Sequence Viewer  
  EDL97750 (Get FASTA)   NCBI Sequence Viewer  
  Q8CH84 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001289146   ⟸   NM_001302217
- UniProtKB: G3V6U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075983   ⟸   ENSRNOT00000092743
RefSeq Acc Id: ENSRNOP00000009034   ⟸   ENSRNOT00000009034
RefSeq Acc Id: ENSRNOP00000076021   ⟸   ENSRNOT00000093032
RefSeq Acc Id: ENSRNOP00000076072   ⟸   ENSRNOT00000093007
RefSeq Acc Id: ENSRNOP00000094592   ⟸   ENSRNOT00000105492
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CH84-F1-model_v2 AlphaFold Q8CH84 1-359 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693838
Promoter ID:EPDNEW_R4360
Type:multiple initiation site
Name:Elavl2_1
Description:ELAV like RNA binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05109,651,732 - 109,651,792EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628611 AgrOrtholog
BioCyc Gene G2FUF-40747 BioCyc
Ensembl Genes ENSRNOG00000006853 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000009034 ENTREZGENE
  ENSRNOP00000009034.7 UniProtKB/TrEMBL
  ENSRNOP00000075983.2 UniProtKB/TrEMBL
  ENSRNOP00000076021.1 UniProtKB/TrEMBL
  ENSRNOP00000094592.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009034 ENTREZGENE
  ENSRNOT00000009034.8 UniProtKB/TrEMBL
  ENSRNOT00000092743.2 UniProtKB/TrEMBL
  ENSRNOT00000093032.2 UniProtKB/TrEMBL
  ENSRNOT00000105492.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ELAD_HU_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ELAV/Hu_RRM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HuB_RRM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HuB_RRM3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hud_Sxl_RNA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:286973 UniProtKB/TrEMBL
NCBI Gene 286973 ENTREZGENE
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Elavl2 PhenoGen
PRINTS HUDSXLRNA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs ELAV_HUD_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1B0GWQ5_RAT UniProtKB/TrEMBL
  A0A1B0GWU2_RAT UniProtKB/TrEMBL
  A0A8I6B178_RAT UniProtKB/TrEMBL
  ELAV2_RAT UniProtKB/Swiss-Prot
  G3V6U4 ENTREZGENE, UniProtKB/TrEMBL
  Q8CH84 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-09 Elavl2  ELAV like RNA binding protein 2  Elavl2  ELAV like neuron-specific RNA binding protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-11 Elavl2  ELAV like neuron-specific RNA binding protein 2  Elavl2  ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-23 Elavl2  ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)  Elavl2_predicted  ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (predicted)  Data Merged 737654 APPROVED
2005-01-20 Elavl2  ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)  Hub  RNA binding protein HuB  Symbol and Name updated 1299863 APPROVED
2005-01-12 Elavl2_predicted  ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2003-02-27 Hub  RNA binding protein HuB      Symbol and Name status set to provisional 70820 PROVISIONAL