Tmem139 (transmembrane protein 139)

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Gene: Tmem139 (transmembrane protein 139) Rattus norvegicus

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Symbol:

Tmem139

Name:

transmembrane protein 139

RGD ID:

1594187

Description:

Predicted to be located in membrane. Orthologous to human TMEM139 (transmembrane protein 139); INTERACTS WITH acrylamide; bisphenol A; diuron.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC680244; LOC680244

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM139 (transmembrane protein 139)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tmem139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem139 (transmembrane protein 139)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TMEM139 (transmembrane protein 139)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem139 (transmembrane protein 139)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	72,113,437 - 72,115,786 (+)	NCBI		GRCr8
mRatBN7.2	4	71,147,072 - 71,149,151 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	71,146,724 - 71,167,399 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	4	71,648,705 - 71,651,861 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	71,650,575 - 71,651,438 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	136,451,731 - 136,454,222 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	70,026,809 - 70,028,734 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	66,076,637 - 66,079,793 (+)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neoplasm Invasiveness (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-diaminodiphenylmethane (ISO)

acrylamide (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dichloroacetic acid (ISO)

diuron (EXP)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

folic acid (ISO)

genistein (ISO)

methylmercury chloride (ISO)

nickel atom (ISO)

O-methyleugenol (ISO)

ozone (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

pravastatin (EXP,ISO)

progesterone (ISO)

propanal (ISO)

quercetin (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

zaragozic acid A (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Tmem139
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	72,113,437 - 72,115,786 (+)	NCBI		GRCr8
mRatBN7.2	4	71,147,072 - 71,149,151 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	71,146,724 - 71,167,399 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	4	71,648,705 - 71,651,861 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	71,650,575 - 71,651,438 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	136,451,731 - 136,454,222 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	70,026,809 - 70,028,734 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	66,076,637 - 66,079,793 (+)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

TMEM139
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	143,284,899 - 143,288,049 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	143,279,957 - 143,288,048 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	142,981,992 - 142,985,142 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	142,692,185 - 142,695,263 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	137,818,928 - 137,822,006 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI
HuRef	7	137,319,401 - 137,322,503 (+)	NCBI		HuRef
CHM1_1	7	142,918,927 - 142,922,028 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	144,640,307 - 144,643,457 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	142,384,156 - 142,387,257 (+)	NCBI

Tmem139
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	42,238,866 - 42,241,489 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	42,238,893 - 42,241,489 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	42,261,932 - 42,264,555 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	42,261,959 - 42,264,555 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	42,211,969 - 42,214,554 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	42,191,566 - 42,194,160 (+)	NCBI		MGSCv36	mm8
Celera	6	42,206,268 - 42,208,853 (+)	NCBI		Celera
Cytogenetic Map	6	B2.1	NCBI
cM Map	6	20.54	NCBI

Tmem139
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955494	369,309 - 371,516 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955494	369,309 - 371,526 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM139
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	180,130,699 - 180,140,945 (+)	NCBI		NHGRI_mPanPan1-v2
PanPan1.1 Ensembl	7	147,770,478 - 147,773,583 (+)	Ensembl	panpan1.1		panPan2

TMEM139
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	6,397,507 - 6,401,385 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	6,380,778 - 6,399,579 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	7,386,566 - 7,388,551 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	6,251,398 - 6,253,391 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	6,250,535 - 6,253,294 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	6,198,790 - 6,200,782 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	6,050,709 - 6,052,702 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	6,125,847 - 6,128,096 (-)	NCBI		UU_Cfam_GSD_1.0

Tmem139
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	12,164,385 - 12,167,869 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936527	736,085 - 739,173 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936527	736,173 - 739,142 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM139
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	6,970,891 - 6,973,394 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	6,970,887 - 6,974,130 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	7,211,799 - 7,215,042 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM139
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	112,167,475 - 112,172,327 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	112,170,253 - 112,171,143 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666072	8,893,511 - 8,896,620 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem139
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624800	11,468,819 - 11,470,751 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624800	11,468,362 - 11,470,732 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem139
1 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	102
Count of miRNA genes:	87
Interacting mature miRNAs:	91
Transcripts:	ENSRNOT00000033775
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	38465774	146803430	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	103194791	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	40433388	85433388	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	43457976	88457976	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	26775591	168368347	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	57486946	102486946	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	70362013	132642728	Rat
61336	Bp21	Blood pressure QTL 21	4.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114705	78881294	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	115089733	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	26907285	75585128	Rat
61475	Aia2	Adjuvant induced arthritis QTL 2	5.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	39505275	73892441	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	40433414	85433414	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	29494195	81006281	Rat
2317577	Eae24	Experimental allergic encephalomyelitis QTL 24			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	4	66993185	72752834	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	26907285	75585128	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	44463908	148090542	Rat
2300179	Bmd50	Bone mineral density QTL 50	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	4	60928534	105928534	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	50119848	146803430	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	62933508	114921294	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	39524264	116179656	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	56647873	149491524	Rat
1578657	Bss12	Bone structure and strength QTL 12	8.9		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	4	60220938	105220938	Rat
1578658	Bss13	Bone structure and strength QTL 13	8		femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	4	60220938	105220938	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	56647776	78882945	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	56647776	78882945	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	56647776	78882945	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	56647776	78882945	Rat
1331807	Rf31	Renal function QTL 31	2.988		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	4	39524264	74726312	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	57114432	81266970	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	59948935	154902892	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	10814170	91360527	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	45456990	146803430	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	65882107	96130297	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	36303261	103194984	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	44463908	148090542	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	70808386	115808386	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5214602	146446691	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	34430484	82490359	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
8552807	Vie4	Viral induced encephalitis QTL 4	7.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	62933508	82490359	Rat
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5214602	78882945	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	44463720	155883716	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	62277855	128289560	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	62879517	107879517	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	58432133	92991462	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	56698790	126192555	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114432	91360801	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	64528739	157573521	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	62933269	87483707	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	32583980	114627242	Rat
631671	Iddm11	Insulin dependent diabetes mellitus QTL 11	3.6	0.0012	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	58635877	78886137	Rat

Markers in Region

RH140969

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	71,148,728 - 71,148,932 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	71,651,439 - 71,651,642	NCBI	Rnor6.0
Rnor_5.0	4	136,453,800 - 136,454,003	UniSTS	Rnor5.0
RGSC_v3.4	4	70,028,735 - 70,028,938	UniSTS	RGSC3.4
Celera	4	66,079,371 - 66,079,574	UniSTS
RH 3.4 Map	4	433.61	UniSTS
Cytogenetic Map	4	q23	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	2	37	52	67	67	36	25	36	6	168	76	33	45	54	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001431872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001056308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002726353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033775 ⟹ ENSRNOP00000036990

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	71,650,575 - 71,651,438 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112830 ⟹ ENSRNOP00000096921

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	71,146,724 - 71,167,399 (+)	Ensembl

RefSeq Acc Id:

XM_006236395 ⟹ XP_006236457

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	72,113,552 - 72,115,786 (+)	NCBI
mRatBN7.2	4	71,147,072 - 71,149,151 (+)	NCBI
Rnor_6.0	4	71,648,705 - 71,651,861 (+)	NCBI
Rnor_5.0	4	136,451,731 - 136,454,222 (+)	NCBI

Sequence:

show sequence

CCCTCTCTCTCTATTCCTGAGGACCCTAGATTATATTTCCAGTCTTTTTAGTTCTGTTGGGTTT
GTCTAATGCTAATGAGGTGAGGGAATAGAGTCCACTGGGACACAGCAGACCACTCCCCTCTCTC
ACACTTACTCACAGCCCAAACTCACAAATAGAGCATTAAAAGCAGTTACAGGAGCTACAGGGTG
CAGTGAAGCCCTTTGTGGGGCTAGCTCCTGATCAGAGCACAGATTTAAGGGCGTGGAGCAAGAA
TCCATTTACTTTCAGGGATTCGGTGAACATTGAAAAGAATTTTTTCTTGTAATGCTCAAAGCAA
AATAACAGTAAGTAAACACAAAACACTAAATAATCAGGTAAAAGCTGAGGCAGAGAAAGGAACG
ATGTGGTTACGCAGTGCAGAATCCAAAGCAGGTTTCACATACAAGTAGGATTTGTGAAAAGTCT
TCTGAGAAGCAAGAGTATACCTCCGACACTTCCTGAGACAAAGAATCCACAGACAGAGCAGCAG
AGGCGTGATATGCCACTCCAATTTCGACCATGGCTCTCTTTATACCCAACAGTGTAAATACACC
ACCGTCTTTGCTCCAGTCTTTCAGGAAAGACAAGTACAAAACAACTCAGGAAGTACTTTGTGCT
TAGGATTGTGACTAGCACCCAAGATGTTTTGAGTAGGACAAGGGAAAGACTAATTCCAACTCTG
GTCCTAAGTACAAAGACCATTGGGAGTGGGAGGGGACAGGGTTTTACCGGGGAAACTCAGGTGG
AGCAGTAACAGGAGGTCAGTCTTGGGAGAAAGGGGTGGAGAAAGACTAGGCCTGAAGGAAGGAT
TAGGGCAGAAGAGAGGGTGGGGCAAGTGGGCTCCGCCTTCTGCCACCAGTGTTCCAGGTCTGCT
AGGGGTTTTCCGCGCGTCCCTGCGAGACAGAGCATGGGCTGACTCAACTGTGACTTGAAGCAAA
CGTCACGCTGACAGGTGCCTGGGAGGGGCGATGGTGCCAAGGCAGCTGTTGGGGAAACTGAAGC
AGCCGTTTCTCTTCCTGAGCAGTGCCTCCCTCCTCCTGGGGCTGGCTTTACTGGTCATACAGCC
TGATGTCGCCCCTGTTGCTTACTTCTTCCTCTGCTTGGCTGGCTTCTGCTTTATCGCTTGCCTC
CTGGCCTGTGTTATGGAACGGTGTCTCCAACCAATGCCAAGTTCAAGGCAGACTGACAATCCAG
AGGCCTCGGGCAATGCACAGGTCAATGAAGCTTTTGAGGTGCCAACCTACGAACAGGCTGTAGT
AGTGATGGATTCACAATCACAGCACCATCTCCAAGAGCTGGAGCAACCACCGCCTTACAGCAGT
ATCATAATATCCCCAGGAATTGAGGGGGCACAGCCTAGCCAACCAGAGAGGCCTGACACAGGCA
GTCAGAAAAGGCGAGTGGGCTCAGAGGGGACAATGACGCCCAGAGGAAACCCTGGAAGAGCTCT
TCGACTTAGGGGTCCACGAGTTGTGTCCACTGCTCCTGATCTGCAAAGCTTGAGGGTGGCCCCA
AAACTGGAGCCTAATACTCCACCCCCTGCCTATGAAATCGGTTTTGCTCACCCTGATGATGACA
GTGTTTTCTATGAAGATAAATGGATACTTCCCTAAGCGATGCTCTCAGAACCTATCACCTGTGA
ACTCATTTGCCCAGCATTTCCTAATATCTATTGAATCAGAAGTTGGTTTTGCCCAAACATCACA
ATTGATGCCTTCAAAGCAGTGGGGAGTTGGGCTCCGGAATGTCCTTCACAGTCGAGATATAAAT
GGCATACCTGGATTCTTCTGGAAACATTCTGGAGCCTACCTGACGAGCAGTACTTCCAGCGTAA
GGTGGAAGAAGAGAGAGATAAGTTACCAAGAGAAGCTGGAGGGGTACCTCGGAGTGACAGTTGT
GTTTCTTCTACTGCAGACACCAAGTCTCGCTGAGATTCCTGATGGGGATGAGAGATTCTAAGGG
TGAGGGGAGCTGAAAAGTTTGCGCAAGAACGGGATGCTAGTAAAAACATAAAAATAACTCGAAT
CGAATCCCAA

hide sequence

RefSeq Acc Id:

XM_063286943 ⟹ XP_063143013

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	72,113,490 - 72,115,786 (+)	NCBI

RefSeq Acc Id:

XM_063286944 ⟹ XP_063143014

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	72,113,437 - 72,115,786 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001418801	(Get FASTA)	NCBI Sequence Viewer
	NP_001418802	(Get FASTA)	NCBI Sequence Viewer
	XP_006236457	(Get FASTA)	NCBI Sequence Viewer
	XP_063143013	(Get FASTA)	NCBI Sequence Viewer
	XP_063143014	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000096921.1

RefSeq Acc Id:

XP_006236457 ⟸ XM_006236395

- UniProtKB:

A0A8I6AMU2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVPRQLLGKLKQPFLFLSSASLLLGLALLVIQPDVAPVAYFFLCLAGFCFIACLLACVMERCLQ
PMPSSRQTDNPEASGNAQVNEAFEVPTYEQAVVVMDSQSQHHLQELEQPPPYSSIIISPGIEGA
QPSQPERPDTGSQKRRVGSEGTMTPRGNPGRALRLRGPRVVSTAPDLQSLRVAPKLEPNTPPPA
YEIGFAHPDDDSVFYEDKWILP

hide sequence

Ensembl Acc Id:

ENSRNOP00000036990 ⟸ ENSRNOT00000033775

Ensembl Acc Id:

ENSRNOP00000096921 ⟸ ENSRNOT00000112830

RefSeq Acc Id:

XP_063143014 ⟸ XM_063286944

RefSeq Acc Id:

XP_063143013 ⟸ XM_063286943

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AC26-F1-model_v2	AlphaFold	D4AC26	1-214	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1594187	AgrOrtholog
BioCyc Gene	G2FUF-45095	BioCyc
Ensembl Genes	ENSRNOG00000028024	Ensembl
	ENSRNOG00000063089	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000112830.1	UniProtKB/TrEMBL
InterPro	TMEM139	UniProtKB/TrEMBL
KEGG Report	rno:680244	UniProtKB/TrEMBL
NCBI Gene	680244	ENTREZGENE
PANTHER	PTHR36294	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 139	UniProtKB/TrEMBL
PhenoGen	Tmem139	PhenoGen
RatGTEx	ENSRNOG00000028024	RatGTEx
	ENSRNOG00000063089	RatGTEx
UniProt	A0A8I6AMU2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Tmem139	transmembrane protein 139	Tmem139	transmembrane protein 139	Data merged from RGD:149736181	737654	PROVISIONAL
2021-08-09	Tmem139	transmembrane protein 139			Symbol and Name status set to provisional	45752	PROVISIONAL
2008-03-05	Tmem139	transmembrane protein 139	LOC680244	hypothetical protein LOC680244	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC680244	hypothetical protein LOC680244	LOC684809	hypothetical protein LOC684809	Data merged from RGD:1585587	1643240	APPROVED
2006-11-20	LOC680244	hypothetical protein LOC680244			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC684809	hypothetical protein LOC684809			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD