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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tertiary allylic alcohol
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Accession:CHEBI:134397 term browser browse the term
Definition:An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to two other carbons (R4,R5 =/= H).
Synonyms:related_synonym: Formula=C3HOR5;   SMILES=C(C(=C(*)*)*)(O)(*)*;   tertiary allylic alcohols



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(+)-abscisic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 increases secretion
multiple interactions
ISO CCL2 protein results in increased secretion of Abscisic Acid
fluridone inhibits the reaction [CCL2 protein results in increased secretion of Abscisic Acid]
CTD PMID:24211328 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
nerolidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP [nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein; nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein]; nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:33212213 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein] CTD PMID:33212213 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Cat catalase multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein] CTD PMID:33212213 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP [nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein CTD PMID:33212213 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Il6 interleukin 6 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein] CTD PMID:33212213 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:33212213 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:33212213 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein] CTD PMID:33212213 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein] CTD PMID:33212213 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:33212213 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein] CTD PMID:33212213 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein] CTD PMID:33212213 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein] CTD PMID:33212213 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein] CTD PMID:33212213 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein] CTD PMID:33212213 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein] CTD PMID:33212213 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
rebaudioside A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases expression ISO rebaudioside A results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO rebaudioside A results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO rebaudioside A results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO rebaudioside A results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO rebaudioside A results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cat catalase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 decreases expression ISO rebaudioside A results in decreased expression of CAV1 mRNA CTD PMID:31655124 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO rebaudioside A results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO rebaudioside A results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Edn1 endothelin 1 decreases expression ISO rebaudioside A results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression ISO rebaudioside A results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO rebaudioside A results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Faslg Fas ligand increases expression ISO rebaudioside A results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO rebaudioside A results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO rebaudioside A results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA] CTD PMID:25554529 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Insr insulin receptor multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO rebaudioside A results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO rebaudioside A results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO rebaudioside A results in increased expression of MMP9 mRNA CTD PMID:31655124 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pf4 platelet factor 4 increases expression ISO rebaudioside A results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO rebaudioside A results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sele selectin E decreases expression ISO rebaudioside A results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO rebaudioside A results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
steviol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA] CTD PMID:25554529 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO steviol results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO steviol results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO steviol binds to and results in increased activity of AHR protein CTD PMID:28887089 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO steviol results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO steviol results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO steviol results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cat catalase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO steviol results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO steviol results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO steviol results in increased expression of CYP1A1 mRNA; steviol results in increased expression of CYP1A1 protein CTD PMID:28887089 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO steviol results in increased expression of CYP1A2 mRNA; steviol results in increased expression of CYP1A2 protein CTD PMID:28887089 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO steviol results in increased expression of CYP1B1 mRNA CTD PMID:28887089 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO steviol results in increased expression of CYP2B6 mRNA CTD PMID:28887089 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
ISO steviol results in increased expression of CYP3A4 mRNA; steviol results in increased expression of CYP3A4 protein
steviol binds to and results in decreased activity of CYP3A4 protein
CTD PMID:28887089 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Edn1 endothelin 1 decreases expression ISO steviol results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression ISO steviol results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO steviol results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Faslg Fas ligand increases expression ISO steviol results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA] CTD PMID:25554529 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO steviol results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO steviol results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA] CTD PMID:25554529 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA] CTD PMID:25554529 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Insr insulin receptor multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO steviol results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO steviol results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PRKAA1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PRKAA1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO steviol results in increased expression of MMP9 mRNA CTD PMID:31655124 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO steviol binds to and results in increased activity of NR1I2 protein CTD PMID:28887089 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pf4 platelet factor 4 increases expression ISO steviol results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA] CTD PMID:25554529 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PRKAA1 mRNA] CTD PMID:25554529 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO steviol results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sele selectin E decreases expression ISO steviol results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO steviol results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
stevioside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases expression ISO stevioside results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP stevioside inhibits the reaction [Scopolamine results in increased activity of ACHE protein] CTD PMID:20871768 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases secretion EXP stevioside results in decreased secretion of ACP5 protein CTD PMID:21089163 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO stevioside results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO stevioside results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO stevioside results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO stevioside results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cat catalase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO stevioside results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO stevioside results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO stevioside results in increased expression of CYP1A1 mRNA CTD PMID:28887089 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO stevioside results in increased expression of CYP1A2 mRNA; stevioside results in increased expression of CYP1A2 protein CTD PMID:28887089 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO stevioside results in increased expression of CYP1B1 mRNA CTD PMID:28887089 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO stevioside binds to and results in decreased activity of CYP3A4 protein
stevioside results in increased expression of CYP3A4 mRNA; stevioside results in increased expression of CYP3A4 protein
CTD PMID:28887089 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Edn1 endothelin 1 decreases expression ISO stevioside results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression ISO stevioside results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO stevioside results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Faslg Fas ligand increases expression ISO stevioside results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO stevioside results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO stevioside results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA] CTD PMID:25554529 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Insr insulin receptor multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO stevioside results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO stevioside results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO stevioside results in increased expression of MMP9 mRNA CTD PMID:31655124 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pf4 platelet factor 4 increases expression ISO stevioside results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA] CTD PMID:25554529 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO stevioside results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] CTD PMID:25554529 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sele selectin E decreases expression ISO stevioside results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO stevioside results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          carbon atom 19609
            organic molecular entity 19609
              olefinic compound 15714
                allylic alcohol 964
                  tertiary allylic alcohol 71
                    (+)-kolavelool + 0
                    1(10),5-germacradien-4-ol + 0
                    2-trans-4'-dihydroabscisic acid 0
                    Avermectin B2a aglycone 0
                    abscisic acids + 1
                    germacrene D-4-ol 0
                    grasshopper ketone 0
                    hawkinsin 0
                    melleolide F 0
                    nerolidol + 16
                    sesterfisherol 0
                    steviol + 60
                    viteagnusin D 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      chalcogen 19450
                        oxygen atom 19423
                          oxygen molecular entity 19423
                            hydroxides 19158
                              organic hydroxy compound 18656
                                alcohol 15085
                                  allylic alcohol 964
                                    tertiary allylic alcohol 71
                                      (+)-kolavelool + 0
                                      1(10),5-germacradien-4-ol + 0
                                      2-trans-4'-dihydroabscisic acid 0
                                      Avermectin B2a aglycone 0
                                      abscisic acids + 1
                                      germacrene D-4-ol 0
                                      grasshopper ketone 0
                                      hawkinsin 0
                                      melleolide F 0
                                      nerolidol + 16
                                      sesterfisherol 0
                                      steviol + 60
                                      viteagnusin D 0
paths to the root