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Gene: Gata6 (GATA binding protein 6) Rattus norvegicus
Symbol: Gata6
Name: GATA binding protein 6
RGD ID: 2666
Description: Exhibits cis-regulatory region sequence-specific DNA binding activity and transcription factor binding activity. Involved in several processes, including positive regulation of BMP signaling pathway; positive regulation of cardiac muscle cell apoptotic process; and regulation of transcription by RNA polymerase II. Localizes to nucleus. Biomarker of congenital diaphragmatic hernia and pulmonary hypertension. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma; congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA6 (GATA binding protein 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-binding protein GATA-GT2; GATA-binding factor 6; GATA-binding protein 6; transcription factor GATA-6
Homo sapiens (human) : GATA6 (GATA binding protein 6)  HGNC  Alliance
Mus musculus (house mouse) : Gata6 (GATA binding protein 6)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GATA6 (GATA binding protein 6)
Canis lupus familiaris (dog) : GATA6 (GATA binding protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata6 (GATA binding protein 6)
Sus scrofa (pig) : GATA6 (GATA binding protein 6)
Chlorocebus sabaeus (African green monkey) : GATA6 (GATA binding protein 6)
Heterocephalus glaber (naked mole-rat) : Gata6 (GATA binding protein 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0182,415,821 - 2,447,087 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,416,552 - 2,446,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,436,500 - 2,465,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,504,264 - 2,534,648 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1182,504,263 - 2,534,648 (+)NCBI
Celera182,065,111 - 2,096,513 (+)NCBICelera
Cytogenetic Map18p13NCBI
RH 3.4 Map1810.8RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gata6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2666
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.