Dr1 (down-regulator of transcription 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dr1 (down-regulator of transcription 1) Rattus norvegicus
Analyze
Symbol: Dr1
Name: down-regulator of transcription 1
RGD ID: 1305201
Description: Predicted to enable RNA polymerase II general transcription initiation factor activity; TBP-class protein binding activity; and core promoter sequence-specific DNA binding activity. Predicted to be involved in several processes, including RNA polymerase II preinitiation complex assembly; regulation of protein deacetylation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of ATAC complex; RNA polymerase II transcription regulator complex; and negative cofactor 2 complex. Orthologous to human DR1 (down-regulator of transcription 1); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: down-regulator of transcription 1, TBP-binding (negative cofactor 2); LOC100910207; LOC289881; NC2-beta; negative cofactor 2-beta; protein Dr1-like; TATA-binding protein-associated phosphoprotein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2141,458,223 - 1,469,578 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl141,458,223 - 1,469,638 (-)Ensembl
Rnor_6.0142,463,651 - 2,475,004 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl141,621,026 - 1,632,378 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl142,463,643 - 2,474,780 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0142,462,579 - 2,473,932 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,005,938 - 2,017,291 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,005,938 - 2,017,291 (-)NCBI
Celera141,480,040 - 1,491,393 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. ATAC-king the complexity of SAGA during evolution. Spedale G, etal., Genes Dev. 2012 Mar 15;26(6):527-41. doi: 10.1101/gad.184705.111.
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:18838386   PMID:19103755   PMID:20508642  


Genomics

Comparative Map Data
Dr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2141,458,223 - 1,469,578 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl141,458,223 - 1,469,638 (-)Ensembl
Rnor_6.0142,463,651 - 2,475,004 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl141,621,026 - 1,632,378 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl142,463,643 - 2,474,780 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0142,462,579 - 2,473,932 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,005,938 - 2,017,291 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,005,938 - 2,017,291 (-)NCBI
Celera141,480,040 - 1,491,393 (-)NCBICelera
Cytogenetic Map14p22NCBI
DR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,345,907 - 93,369,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl193,345,907 - 93,369,493 (+)EnsemblGRCh38hg38GRCh38
GRCh37193,811,464 - 93,835,050 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,584,066 - 93,600,737 (+)NCBINCBI36hg18NCBI36
Build 34193,523,498 - 93,540,167NCBI
Celera192,065,544 - 92,082,224 (+)NCBI
Cytogenetic Map1p22.1NCBI
HuRef191,933,028 - 91,949,702 (+)NCBIHuRef
CHM1_1193,926,443 - 93,943,112 (+)NCBICHM1_1
T2T-CHM13v2.0193,191,628 - 93,215,212 (+)NCBI
Dr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395108,416,763 - 108,428,387 (+)NCBIGRCm39mm39
GRCm39 Ensembl5108,416,763 - 108,428,392 (+)Ensembl
GRCm385108,268,897 - 108,280,521 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5108,268,897 - 108,280,526 (+)EnsemblGRCm38mm10GRCm38
MGSCv375108,697,916 - 108,709,540 (+)NCBIGRCm37mm9NCBIm37
MGSCv365108,509,199 - 108,520,823 (+)NCBImm8
Celera5105,388,795 - 105,400,436 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map552.82NCBI
Dr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554231,262,633 - 1,281,870 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554231,262,633 - 1,281,870 (-)NCBIChiLan1.0ChiLan1.0
DR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1194,746,109 - 94,762,736 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,746,109 - 94,762,736 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0196,014,758 - 96,031,402 (+)NCBIMhudiblu_PPA_v0panPan3
DR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1655,687,581 - 55,717,118 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl655,693,752 - 55,716,516 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha658,394,802 - 58,423,443 (-)NCBI
ROS_Cfam_1.0656,062,710 - 56,091,972 (-)NCBI
ROS_Cfam_1.0 Ensembl656,066,414 - 56,091,908 (-)Ensembl
UMICH_Zoey_3.1655,742,084 - 55,770,728 (-)NCBI
UNSW_CanFamBas_1.0655,726,996 - 55,756,232 (-)NCBI
UU_Cfam_GSD_1.0656,180,439 - 56,209,096 (-)NCBI
Dr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058103,094,464 - 103,112,245 (+)NCBI
SpeTri2.0NW_0049365375,835,774 - 5,853,509 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4123,815,456 - 123,835,826 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14123,815,088 - 123,835,875 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24135,471,129 - 135,491,365 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12039,873,024 - 39,890,090 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2039,870,814 - 39,890,106 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603378,142,864 - 78,159,920 (+)NCBIVero_WHO_p1.0
Dr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247424,263,288 - 4,282,609 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247424,263,288 - 4,282,097 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH131134  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2141,458,343 - 1,458,530 (+)MAPPERmRatBN7.2
Rnor_6.0142,463,772 - 2,463,958NCBIRnor6.0
Rnor_6.0141,621,146 - 1,621,332NCBIRnor6.0
Rnor_5.0142,462,700 - 2,462,886UniSTSRnor5.0
Rnor_5.0141,616,377 - 1,616,563UniSTSRnor5.0
RGSC_v3.4142,006,059 - 2,006,245UniSTSRGSC3.4
Celera141,480,161 - 1,480,347UniSTS
RH 3.4 Map1431.9UniSTS
Cytogenetic Map14p22UniSTS
AI179296  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2141,459,971 - 1,460,066 (+)MAPPERmRatBN7.2
Rnor_6.0142,465,400 - 2,465,494NCBIRnor6.0
Rnor_6.0141,622,774 - 1,622,868NCBIRnor6.0
Rnor_5.0142,464,328 - 2,464,422UniSTSRnor5.0
Rnor_5.0141,618,005 - 1,618,099UniSTSRnor5.0
RGSC_v3.4142,007,687 - 2,007,781UniSTSRGSC3.4
Celera141,481,789 - 1,481,883UniSTS
RH 3.4 Map1425.3UniSTS
Cytogenetic Map14p22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14121760611030812Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14121760616960180Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:653
Count of miRNA genes:294
Interacting mature miRNAs:382
Transcripts:ENSRNOT00000000080
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 22 23 11 11 11 61 17 39 6
Below cutoff 3 19 33 29 8 29 8 10 12 17 3 4 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000080   ⟹   ENSRNOP00000000080
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl141,458,223 - 1,469,638 (-)Ensembl
Rnor_6.0 Ensembl141,621,026 - 1,632,378 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000074874   ⟹   ENSRNOP00000064336
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl142,463,643 - 2,474,780 (-)Ensembl
RefSeq Acc Id: NM_001011914   ⟹   NP_001011914
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2141,458,223 - 1,469,578 (-)NCBI
Rnor_6.0142,463,651 - 2,475,004 (-)NCBI
Rnor_5.0142,462,579 - 2,473,932 (-)NCBI
RGSC_v3.4142,005,938 - 2,017,291 (-)RGD
Celera141,480,040 - 1,491,393 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001011914 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83822 (Get FASTA)   NCBI Sequence Viewer  
  EDL84000 (Get FASTA)   NCBI Sequence Viewer  
  Q5XI68 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001011914   ⟸   NM_001011914
- UniProtKB: Q5XI68 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000064336   ⟸   ENSRNOT00000074874
RefSeq Acc Id: ENSRNOP00000000080   ⟸   ENSRNOT00000000080
Protein Domains
Histone-fold

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI68-F1-model_v2 AlphaFold Q5XI68 1-176 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305201 AgrOrtholog
BioCyc Gene G2FUF-16656 BioCyc
Ensembl Genes ENSRNOG00000000070 Ensembl, ENTREZGENE
  ENSRNOG00000048308 Ensembl
Ensembl Protein ENSRNOP00000000080 ENTREZGENE
Ensembl Transcript ENSRNOT00000000080 ENTREZGENE
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7111461 IMAGE-MGC_LOAD
InterPro CBFA_NFYB_domain UniProtKB/Swiss-Prot
  Histone-fold UniProtKB/Swiss-Prot
  Ncb2 UniProtKB/Swiss-Prot
KEGG Report rno:289881 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94897 IMAGE-MGC_LOAD
NCBI Gene 289881 ENTREZGENE
PANTHER PTHR46138 UniProtKB/Swiss-Prot
Pfam CBFD_NFYB_HMF UniProtKB/Swiss-Prot
PhenoGen Dr1 PhenoGen
Superfamily-SCOP SSF47113 UniProtKB/Swiss-Prot
UniProt NC2B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Dr1  down-regulator of transcription 1  LOC100910207  protein Dr1-like  Data Merged 737654 PROVISIONAL
2015-08-19 Dr1  down-regulator of transcription 1  Dr1  down-regulator of transcription 1, TBP-binding (negative cofactor 2)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-03-04 Dr1  down-regulator of transcription 1, TBP-binding (negative cofactor 2)  Dr1  down-regulator of transcription 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100910207  protein Dr1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Dr1  down-regulator of transcription 1  Dr1_predicted  down-regulator of transcription 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dr1_predicted  down-regulator of transcription 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED