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Gene: Gldc (glycine decarboxylase) Rattus norvegicus
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Symbol: Gldc
Name: glycine decarboxylase
Description: Exhibits anion binding activity; enzyme binding activity; and glycine dehydrogenase (decarboxylating) activity. Involved in glycine decarboxylation via glycine cleavage system and protein-containing complex assembly. Localizes to the glycine cleavage complex and mitochondrion. Human ortholog(s) of this gene implicated in glycine encephalopathy. Orthologous to human GLDC (glycine decarboxylase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; folate cycle metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating, glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial
Orthologs:
Homo sapiens (human) : GLDC (glycine decarboxylase)  HGNC  Alliance
Mus musculus (house mouse) : Gldc (glycine decarboxylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gldc (glycine decarboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : GLDC (glycine decarboxylase)
Canis lupus familiaris (dog) : GLDC (glycine decarboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gldc (glycine decarboxylase)
Sus scrofa (pig) : GLDC (glycine decarboxylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01248,295,140 - 248,377,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,297,331 - 248,377,093 (-)Ensembl
Rnor_5.01255,544,863 - 255,624,599 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,846,690 - 233,925,736 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11234,011,236 - 234,089,583 (-)NCBI
Celera1225,029,994 - 225,108,807 (-)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gldc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308660
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.