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Gene: Gldc (glycine decarboxylase) Ictidomys tridecemlineatus

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Symbol:

Gldc

Name:

glycine decarboxylase

RGD ID:

12544156

Description:

ENCODES a protein that exhibits enzyme binding (ortholog); glycine binding (ortholog); glycine dehydrogenase (decarboxylating) activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glycine decarboxylation via glycine cleavage system (ortholog); protein-containing complex assembly (ortholog); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; folate cycle metabolic pathway; ASSOCIATED WITH chromosome 9p deletion syndrome (ortholog); COVID-19 (ortholog); Developmental Disabilities (ortholog); FOUND IN glycine cleavage complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

glycine dehydrogenase (decarboxylating), mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GLDC (glycine decarboxylase)	NCBI	Ortholog
Mus musculus (house mouse):	Gldc (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Gldc (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gldc (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GLDC (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GLDC (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GLDC (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GLDC (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gldc (glycine decarboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	142,555,653 - 142,642,377 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936539	1,007,820 - 1,095,054 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936539	1,008,340 - 1,095,044 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 9p deletion syndrome (ISO)

COVID-19 (ISO)

Developmental Disabilities (ISO)

Generalized Epilepsy (ISO)

genetic disease (ISO)

glycine encephalopathy (ISO)

glycine encephalopathy 1 (ISO)

hydrocephalus (ISO)

neural tube defect (ISO)

Neurodevelopmental Disorders (ISO)

obesity (ISO)

retinitis pigmentosa (ISO)

Smith-Magenis syndrome (ISO)

stomach cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (IEA,ISO)

glycine catabolic process (IEA)

glycine decarboxylation via glycine cleavage system (IEA,ISO)

protein-containing complex assembly (ISO)

Cellular Component

glycine cleavage complex (IEA,ISO)

mitochondrion (IEA)

nucleoplasm (IEA)

plasma membrane (IEA)

Molecular Function

enzyme binding (ISO)

glycine binding (IEA,ISO)

glycine dehydrogenase (decarboxylating) activity (IEA,ISO)

lyase activity (IEA)

oxidoreductase activity (IEA)

pyridoxal phosphate binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

dihydropyrimidine dehydrogenase deficiency pathway (ISO)

dimethylglycine dehydrogenase deficiency pathway (ISO)

folate cycle metabolic pathway (ISO)

nonketotic hyperglycinemia pathway (ISO)

sarcosinemia pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Gldc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	142,555,653 - 142,642,377 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936539	1,007,820 - 1,095,054 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936539	1,008,340 - 1,095,044 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GLDC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	6,532,467 - 6,645,729 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	6,532,467 - 6,645,729 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	6,532,467 - 6,645,729 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	6,522,464 - 6,635,692 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	6,522,468 - 6,635,650	NCBI
Celera	9	6,469,938 - 6,583,174 (-)	NCBI		Celera
Cytogenetic Map	9	p24.1	NCBI
HuRef	9	6,487,440 - 6,600,082 (-)	NCBI		HuRef
CHM1_1	9	6,533,234 - 6,646,419 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	6,537,521 - 6,650,780 (-)	NCBI		T2T-CHM13v2.0

Gldc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	30,075,847 - 30,152,829 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	30,075,847 - 30,152,829 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	30,098,441 - 30,175,441 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	30,098,447 - 30,175,429 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	30,172,937 - 30,249,908 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	30,164,444 - 30,241,415 (-)	NCBI		MGSCv36	mm8
Celera	19	30,873,665 - 30,951,190 (-)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	24.87	NCBI

Gldc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	237,296,753 - 237,375,620 (-)	NCBI		GRCr8
mRatBN7.2	1	227,883,249 - 227,962,119 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	227,883,249 - 227,962,097 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	236,285,270 - 236,364,242 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	243,214,954 - 243,293,934 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	236,037,217 - 236,116,284 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	248,295,140 - 248,377,122 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	248,297,331 - 248,377,093 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	255,544,863 - 255,624,599 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	233,846,690 - 233,925,736 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	234,011,236 - 234,089,583 (-)	NCBI
Celera	1	225,029,994 - 225,108,807 (-)	NCBI		Celera
Cytogenetic Map	1	q52	NCBI

Gldc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	10,431,983 - 10,533,002 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955434	10,431,434 - 10,533,118 (-)	NCBI	ChiLan1.0	ChiLan1.0

GLDC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	117,935,713 - 118,045,297 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	117,941,661 - 118,051,245 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	6,347,381 - 6,456,042 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	6,527,242 - 6,635,778 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	6,527,242 - 6,635,779 (-)	Ensembl	panpan1.1		panPan2

GLDC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	27,491,639 - 27,584,450 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	27,414,834 - 27,584,450 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	26,274,927 - 26,367,677 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	28,350,544 - 28,443,332 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	28,265,114 - 28,443,675 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	27,074,254 - 27,167,008 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	26,893,508 - 26,986,195 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	27,562,632 - 27,654,945 (-)	NCBI		UU_Cfam_GSD_1.0

GLDC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	215,608,849 - 215,715,059 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	215,608,854 - 215,715,062 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

GLDC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	72,876,992 - 72,990,671 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	72,877,017 - 72,990,668 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	61,215,190 - 61,329,981 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gldc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	11,022,691 - 11,134,377 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	11,022,691 - 11,133,950 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005327970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000015776 ⟹ ENSSTOP00000014117

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936539	1,007,820 - 1,095,054 (-)	Ensembl

RefSeq Acc Id:

XM_005327970 ⟹ XP_005328027

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	142,555,653 - 142,642,377 (-)	NCBI
SpeTri2.0	NW_004936539	1,008,340 - 1,095,044 (-)	NCBI

Sequence:

show sequence

CCTCGGGTGCAGTTACAACTTTGAGTCAGAGTTGGGGTTGACTGCTGCACTCATTCATTGCCTC
CGAGCTGTATCTTCTGTCCCTCCGTAATCCCACGGGAAGGGGCTCCAGGCCAGACGCAGCTGCC
ACCCGGGGACTGAGGCCAGAGGAGGGAGCCCAGAGTTTCGCTGACCCTCCCGGGCTGGGGAGGA
GACGGCGACTGAGTCCATGCAGTCGTGTGCCAAGGCATGGGGGCTGCGCCTGGGATGTGGAGTC
GGGGGCGGCCGCCGTCTGGCTGGGGGCGCGGGCCCCAGTTGGGCGCCGCGGAGCCGGGACAGCA
GTAGCGGCGGTGGGGACAGCGGCGCGCCTGGGGCCTCGCGCCTCCTCGAGCGCTTCCTGCCCAG
ACACGACGACTTTGCTCGGAGACATATCGGCCCTGGGGACAAAGACCAGAGAGAGATGCTACAG
GCCCTGGGGCTGGCGAGCATTGATGAACTGATCGAGAAGACGGTCCCTGCCAGCATCCGCTTGA
AGAGACCCTTGAAAATGGAAGACCCTATTTGTGAAAATGAAATCCTTGCAACTCTGCGTACCAT
TTCCAGCAAAAACCAGATTTGGAGATCGTATATTGGCATGGGCTATTATAACTGCTCAGTGCCA
CAGACCATTTTGAGGAACTTACTGGAGAACTCAGGATGGGTCACCCAGTACACCCCATACCAGC
CAGAGGTGTCTCAGGGGAGGTTGGAGAGTTTACTCAACTACCAGACCATGGTGTGTGACATCAC
AGGCATGGACATGGCCAATGCATCCCTGCTGGATGAGGCGACCGCAGCTGCTGAGGCGATGCAG
CTGTGCCACAGACACAACAAGAGGAGGAAATTTTTTGTTGACCCTCGTTGCCACCCACAAACAA
TAGCTGTCATCCAGACTCGAGCCAAGCACCGTGGAGTCCTCATTGAGCTGAAGTTACCCCATGA
AATGGACTTCAGTGGAAAAGATGTCAGTGGGGTGTTGTTCCAATACCCAGATACCGAGGGGAAG
GTGGAAGACTTTACAGAACTTGTGGAGAGAGCCCATGAGACTGGGACCCTGACCTGCTGTGCTA
CTGACCTTCTAGCCCTGTGTATCTTGAGGCCACCAGGAGAGTTTGGGGTGGATATTGCCCTGGG
CAACTCACAGAGATTTGGAGTGCCACTGGGCTACGGCGGACCACATGCAGCCTTTTTTGCTGTC
AGAGAAAGCTTGGTGAGGATGATGCCTGGAAGGATGGTAGGGGTAACAAGGGATGCCACCGGGA
AAGAAGTGTATCGTCTTGCTCTTCAAACCAGGGAGCAACATATCCGGAGAGACAAAGCTACCAG
CAACATCTGCACAGCTCAGGCCCTCTTGGCAAATATGGCTGCCATGTTTGCAATCTACCATGGT
TCCCAAGGGCTGAAGCATATTGCTAGGAGGGTACATAATGCCACTTTGATTTTGTCTGAAGGTC
TCAGGCGAGCAGGGCATAAACTCCAGCATGACCTGTTCTTTGACACCTTGAAGGTTCAGTGTGG
CTGCTCAGTGAAAGAGGTCTTGAGCAGGGCTGCCCAGCGGCAAATCAATTTTCGGCTCTTTGAG
GATGGCACACTTGGTATTTCTCTTGATGAAACAGTCAATGAAAAAGATCTCGATGATTTGTTAT
GGATCTTTGGCTGTGAGTCATCTGCAGAACTGGTGGCTGAAAGCATGGGAGAGGAATGGAGAGG
TATTCCAGGATCTGCATTCAAGAGAACTAGCCCATTCCTCACACATCAAGTGTTCAACAGCTAT
CACTCAGAAACAAATATTGTCCGGTACATGAAGAAACTAGAGAACAAAGACATTTCCCTTGTTC
ACAGCATGATTCCACTGGGATCCTGTACCATGAAGCTCAATAGCTCATCTGAACTCACACCCAT
CACATGGAAAGAATTTGCAAACATCCACCCCTTTGTGCCTCTGGACCAAGCTCAAGGATACCAG
CAGCTATTCCGAGAGCTTGAGAAAGATTTGTGTGAACTCACAGGTTATGATCAAGTCTCTTTCC
AGCCTAACAGCGGAGCCCAGGGGGAATATGCTGGACTGGCCACAATCCGAGCATACTTAGACCG
GAAAGGAGAGAGGCACAGAACGGTTTGCCTCATTCCGAAATCAGCACATGGTACCAATCCAGCA
AGTGCCCACATGGCAGGCATGAAGATTCAGCCTGTAGAAGTGGATAAATATGGCAATATCGACG
CTGCTCACCTCAAGGCCATGGTGGATAAACACAAGGAGAACCTGGCTGCCATCATGATCACGTA
CCCATCCACTAACGGGGTGTTTGAAGAGAACATCAGTGATGTGTGTGCTCTGATCCACCAACAT
GGAGGGCAGGTCTATCTCGATGGGGCCAATATGAATGCTCAGGTGGGAATCTGTCGTCCTGGAG
ACTTTGGGTCTGATGTCTCACACCTAAATCTTCACAAGACCTTCTGTATTCCCCATGGAGGAGG
TGGCCCTGGCATGGGGCCCATTGGAGTGAAGAAGCATCTTGTCCCCTTTCTGCCCAATCATCCC
ATCATTGCAGTAAAGCCGAATGAGGACACCTGGCCTGTGGGGACCGTCAGTGCAGCCCCATGGG
GCTCCAGTTCCATCTTGCCCATTTCCTGGGCTTATATTAAGATGATGGGAGGCAAAGGCCTTAA
ACAGGCCACAGAAATTGCTATATTAAATGCCAACTACATGGCGAAGCGATTAGAAAAACACTAT
AGAGTCCTTTTTAGGGGTGCAAGAGGTTTTGTGGCTCATGAGTTTATTTTGGACACAAGACCAT
TCAAAAAGTCAGCAAATATTGATGCTGTGGATGTGGCCAAGAGGCTTCAAGATTATGGATTTCA
TGCCCCCACCATGTCCTGGCCTGTGGCAGGAACCCTCATGGTTGAGCCCACTGAGTCAGAAGAC
AAGGCAGAGCTGGACAGATTCTGTGATGCCATGATCAACATTCGGCAGGAAATTGCTGACATTG
AAGAGGGCCGCATTGACCCTAGGGTCAATCCATTAAAGATGTCTCCACACTCCTTGACCTGTGT
CACATCCTCCCACTGGGATCGTCCATATTCCAGAGAGGTGGCAGCATTCCCACTTCCCTTTGTG
AAACCAGAGAACAAATTCTGGCCAACCATTGCCCGGATTGATGACATATATGGAGATCAGCATC
TGTTCTGTACCTGCCCACCCATGGAAGTTTATGAGTCCCCATTTTCTGAACAGAAGAGAGCTTC
TTCTTAATATTCTCTCCCTGCTACCAAGTTGATGTCTCTCCCTGGAGCATTTGATAAGCAATAA
ATATTTCATCTCCCACCCAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005328027	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000014117.3
GenBank Protein	KAG3287206	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005328027 ⟸ XM_005327970

- UniProtKB:

I3MQC0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQSCAKAWGLRLGCGVGGGRRLAGGAGPSWAPRSRDSSSGGGDSGAPGASRLLERFLPRHDDFA
RRHIGPGDKDQREMLQALGLASIDELIEKTVPASIRLKRPLKMEDPICENEILATLRTISSKNQ
IWRSYIGMGYYNCSVPQTILRNLLENSGWVTQYTPYQPEVSQGRLESLLNYQTMVCDITGMDMA
NASLLDEATAAAEAMQLCHRHNKRRKFFVDPRCHPQTIAVIQTRAKHRGVLIELKLPHEMDFSG
KDVSGVLFQYPDTEGKVEDFTELVERAHETGTLTCCATDLLALCILRPPGEFGVDIALGNSQRF
GVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTA
QALLANMAAMFAIYHGSQGLKHIARRVHNATLILSEGLRRAGHKLQHDLFFDTLKVQCGCSVKE
VLSRAAQRQINFRLFEDGTLGISLDETVNEKDLDDLLWIFGCESSAELVAESMGEEWRGIPGSA
FKRTSPFLTHQVFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELTPITWKEF
ANIHPFVPLDQAQGYQQLFRELEKDLCELTGYDQVSFQPNSGAQGEYAGLATIRAYLDRKGERH
RTVCLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAAHLKAMVDKHKENLAAIMITYPSTNG
VFEENISDVCALIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMG
PIGVKKHLVPFLPNHPIIAVKPNEDTWPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATEI
AILNANYMAKRLEKHYRVLFRGARGFVAHEFILDTRPFKKSANIDAVDVAKRLQDYGFHAPTMS
WPVAGTLMVEPTESEDKAELDRFCDAMINIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHW
DRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLFCTCPPMEVYESPFSEQKRASS

hide sequence

Ensembl Acc Id:

ENSSTOP00000014117 ⟸ ENSSTOT00000015776

Protein Domains

Aromatic amino acid beta-eliminating lyase/threonine Glycine cleavage system P-protein N-terminal Glycine dehydrogenase C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000015771	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000015776.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.640.10	UniProtKB/TrEMBL
	3.90.1150.10	UniProtKB/TrEMBL
InterPro	ArAA_b-elim_lyase/Thr_aldolase	UniProtKB/TrEMBL
	GcvP	UniProtKB/TrEMBL
	GDC-P_C	UniProtKB/TrEMBL
	GDC-P_N	UniProtKB/TrEMBL
	GDC_P	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_major	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_small	UniProtKB/TrEMBL
NCBI Gene	Gldc	ENTREZGENE
PANTHER	GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR11773	UniProtKB/TrEMBL
Pfam	Beta_elim_lyase	UniProtKB/TrEMBL
	GcvP2_C	UniProtKB/TrEMBL
	GDC-P	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53383	UniProtKB/TrEMBL
UniProt	I3MQC0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB