vitamin K - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	vitamin K	go back to main search page
Accession:	CHEBI:28384	browse the term
Definition:	Any member of a group of fat-soluble 2-methyl-1,4-napthoquinones that exhibit biological activity against vitamin K deficiency. Vitamin K is required for the synthesis of prothrombin and certain other blood coagulation factors.
Synonyms:	related_synonym:	vitamin K vitamer; vitamin K vitamers; vitamine K; vitamins K
	alt_id:	CHEBI:10009; CHEBI:27301; CHEBI:27307
	xref:	CAS:12001-79-5; KEGG:C01628
	xref_mesh:	MESH:D014812
	xref:	MetaCyc:CPD-11501; PMID:26413183; PMID:33255760; PMID:34109217; Wikipedia:Vitamin_K

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Genes (1259)

vitamin K

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin alpha 2, smooth muscle

multiple interactions

[Warfarin co-treated with Vitamin K co-treated with Quercetin] results in increased expression of ACTA2 mRNA

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

apolipoprotein E

affects abundance
affects uptake

APOE protein affects the abundance of Vitamin K
APOE protein affects the uptake of Vitamin K

PMID:15952022 PMID:16847429

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

axin 2

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of AXIN2 mRNA; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of AXIN2 mRNA]

NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231

G

Axl receptor tyrosine kinase

multiple interactions
increases expression

Vitamin K inhibits the reaction [Warfarin results in decreased expression of AXL protein modified form]
Vitamin K results in increased expression of AXL protein modified form

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

bone gamma-carboxyglutamate protein

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of BGLAP mRNA; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of BGLAP mRNA]

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

catalase

multiple interactions

Vitamin K inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cyclin D1

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of CCND1 mRNA; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of CCND1 mRNA]

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

calponin 1

multiple interactions

[Warfarin co-treated with Vitamin K co-treated with Quercetin] results in increased expression of CNN1 mRNA

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

collagen type I alpha 1 chain

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of COL1A1 mRNA; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of COL1A1 mRNA]

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

colony stimulating factor 2

multiple interactions

Vitamin K inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CSF2 mRNA]

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions
decreases expression
affects expression

Lipopolysaccharides promotes the reaction [Vitamin K deficiency results in decreased expression of CYP11A1 mRNA]; Lipopolysaccharides promotes the reaction [Vitamin K deficiency results in decreased expression of CYP11A1 protein]
Vitamin K deficiency results in decreased expression of CYP11A1 mRNA; Vitamin K deficiency results in decreased expression of CYP11A1 protein
Vitamin K affects the expression of CYP11A1 mRNA

PMID:16844298 PMID:21894328

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

fibrinogen gamma chain

affects expression

Vitamin K affects the expression of FGG mRNA

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

farnesyltransferase, CAAX box, subunit alpha

affects expression

Vitamin K affects the expression of FNTA mRNA

NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460

G

growth arrest specific 6

affects carboxylation

Vitamin K affects the carboxylation of GAS6 protein

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

G

glutamic--pyruvic transaminase

multiple interactions

Vitamin K affects the reaction [9,10-Dimethyl-1,2-benzanthracene affects the activity of GPT protein]

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glycogen synthase kinase 3 beta

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein]

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

interleukin 17A

multiple interactions

Vitamin K inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL17A mRNA]

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 1 beta

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of IL6 mRNA

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

lanosterol synthase

affects expression

Vitamin K affects the expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

matrix Gla protein

multiple interactions

[Vitamin K co-treated with Warfarin] results in increased carboxylation of MGP protein

NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667

G

mevalonate diphosphate decarboxylase

affects expression

Vitamin K affects the expression of MVD mRNA

NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971

G

myosin heavy chain 1

multiple interactions

[Warfarin co-treated with Vitamin K co-treated with Quercetin] results in increased expression of MYH1 mRNA

NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295

G

NUMB, endocytic adaptor protein

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of NUMB mRNA; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of NUMB mRNA]

NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354

G

orosomucoid 1

affects expression

Vitamin K affects the expression of ORM1 mRNA

NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154

G

protein S

multiple interactions

Vitamin K affects the carboxylation of and affects the secretion of PROS1 protein

NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286

G

parathyroid hormone

increases activity

Vitamin K results in increased activity of PTH protein

NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530

G

Rab geranylgeranyltransferase subunit alpha

affects expression

Vitamin K affects the expression of RABGGTA mRNA

NCBI chr15:29,206,328...29,213,398
Ensembl chr15:29,206,157...29,213,348

G

Rab geranylgeranyltransferase subunit beta

affects expression

Vitamin K affects the expression of RABGGTB mRNA

NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

Vitamin K deficiency promotes the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

affects expression

Vitamin K affects the expression of RRAD mRNA

NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417

G

RUNX family transcription factor 2

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA]

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

secreted phosphoprotein 1

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of SPP1 mRNA

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

transgelin

multiple interactions

[Warfarin co-treated with Vitamin K co-treated with Quercetin] results in increased expression of TAGLN mRNA

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

transcription factor 4

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of TCF4 mRNA; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of TCF4 mRNA]

NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425

G

transglutaminase 2

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of and results in increased activity of TGM2 protein; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of and results in increased activity of TGM2 protein]

NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981

G

tumor necrosis factor

multiple interactions

[Warfarin co-treated with Vitamin K] results in increased expression of TNF mRNA

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

UbiA prenyltransferase domain containing 1

increases metabolic processing
multiple interactions

UBIAD1 protein results in increased metabolism of Vitamin K metabolite
[UBIAD1 protein results in increased metabolism of Vitamin K metabolite] which results in increased chemical synthesis of menatetrenone

NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271

G

vitamin K epoxide reductase complex, subunit 1

increases secretion

VKORC1 protein results in increased secretion of Vitamin K

NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008

G

vitamin K epoxide reductase complex, subunit 1-like 1

increases secretion

VKORC1L1 protein results in increased secretion of Vitamin K

NCBI chr12:26,717,959...26,768,193
Ensembl chr12:26,623,976...26,768,225

menadione

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

affects expression

Vitamin K 3 affects the expression of A2M mRNA

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

ATP binding cassette subfamily B member 11

decreases expression

Vitamin K 3 results in decreased expression of ABCB11 mRNA

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily B member 7

affects expression

Vitamin K 3 affects the expression of ABCB7 mRNA

NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858

G

ATP binding cassette subfamily C member 3

affects expression

Vitamin K 3 affects the expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily D member 4

decreases expression

Vitamin K 3 results in decreased expression of ABCD4 mRNA

NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276

G

ATP binding cassette subfamily G member 2

affects expression

Vitamin K 3 affects the expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

abhydrolase domain containing 14b

affects expression

Vitamin K 3 affects the expression of ABHD14B mRNA

NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

Vitamin K 3 results in increased expression of ABHD4 mRNA

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

affects expression

Vitamin K 3 affects the expression of ABHD5 mRNA

NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447

G

ABR activator of RhoGEF and GTPase

affects expression

Vitamin K 3 affects the expression of ABR mRNA

NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505

G

acetyl-CoA acetyltransferase 2

affects expression

Vitamin K 3 affects the expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

aconitase 1

affects activity

Vitamin K 3 affects the activity of ACO1 protein

NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391

G

aconitase 2

affects expression

Vitamin K 3 affects the expression of ACO2 mRNA

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA thioesterase 13

affects expression

Vitamin K 3 affects the expression of ACOT13 mRNA

NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851

G

acyl-CoA synthetase long-chain family member 1

affects expression

Vitamin K 3 affects the expression of ACSL1 mRNA

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase short-chain family member 1

affects expression

Vitamin K 3 affects the expression of ACSS1 mRNA

NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325

G

actin related protein 3B

affects expression

Vitamin K 3 affects the expression of ACTR3B mRNA

NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441

G

ADAM metallopeptidase domain 19

decreases expression

Vitamin K 3 results in decreased expression of ADAM19 mRNA

NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105

G

ADAM metallopeptidase domain 9

affects expression

Vitamin K 3 affects the expression of ADAM9 mRNA

NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917

G

adenylate cyclase 3

affects expression
decreases expression

Vitamin K 3 affects the expression of ADCY3 mRNA
Vitamin K 3 results in decreased expression of ADCY3 mRNA

PMID:12414654 PMID:20044591

NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686

G

adducin 3

affects expression

Vitamin K 3 affects the expression of ADD3 mRNA

NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124

G

adhesion G protein-coupled receptor A3

affects expression

Vitamin K 3 affects the expression of ADGRA3 mRNA

NCBI chr14:60,874,719...60,976,341
Ensembl chr14:60,874,715...60,976,332

G

adhesion G protein-coupled receptor V1

affects expression

Vitamin K 3 affects the expression of ADGRV1 mRNA

NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688

G

adenosine kinase

affects expression

Vitamin K 3 affects the expression of ADK mRNA

NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510

G

argonaute RISC component 1

affects expression

Vitamin K 3 affects the expression of AGO1 mRNA

NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546

G

1-acylglycerol-3-phosphate O-acyltransferase 3

affects expression

Vitamin K 3 affects the expression of AGPAT3 mRNA

NCBI chr20:10,330,960...10,415,358
Ensembl chr20:10,384,507...10,415,358

G

anterior gradient 2, protein disulphide isomerase family member

affects expression

Vitamin K 3 affects the expression of AGR2 mRNA

NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371

G

aryl hydrocarbon receptor

affects expression

Vitamin K 3 affects the expression of AHR mRNA

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

autoimmune regulator

decreases expression

Vitamin K 3 results in decreased expression of AIRE mRNA

NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060

G

A-kinase anchoring protein 12

affects expression

Vitamin K 3 affects the expression of AKAP12 mRNA

NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886

G

A-kinase anchoring protein 9

affects expression

Vitamin K 3 affects the expression of AKAP9 mRNA

NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606

G

A-kinase interacting protein 1

affects expression

Vitamin K 3 affects the expression of AKIP1 mRNA

NCBI chr 1:163,734,730...163,743,648
Ensembl chr 1:163,734,798...163,743,648

G

aldo-keto reductase family 1 member B10

increases expression

Vitamin K 3 results in increased expression of AKR1B10 mRNA

PMID:23410634 PMID:34767876

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member C1

affects expression

Vitamin K 3 affects the expression of AKR1C1 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C2

increases expression

Vitamin K 3 results in increased expression of AKR1C2 mRNA

PMID:12414654 PMID:23410634

NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764

G

aldo-keto reductase family 7, member A2

multiple interactions
increases metabolic processing
decreases response to substance

AKR7A2 protein inhibits the reaction [Vitamin K 3 results in decreased abundance of Glutathione]; AKR7A2 protein inhibits the reaction [Vitamin K 3 results in increased abundance of Reactive Oxygen Species]
AKR7A5 protein results in increased metabolism of Vitamin K 3
AKR7A2 protein results in decreased susceptibility to Vitamin K 3

PMID:22001351 PMID:24590062

NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909

G

albumin

affects expression

Vitamin K 3 affects the expression of ALB mRNA

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 18 family, member A1

affects expression

Vitamin K 3 affects the expression of ALDH18A1 mRNA

NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890

G

aldehyde dehydrogenase 1 family, member A1

affects expression

Vitamin K 3 affects the expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A3

affects expression

Vitamin K 3 affects the expression of ALDH1A3 mRNA

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

G

aldehyde dehydrogenase 2 family member

affects expression

Vitamin K 3 affects the expression of ALDH2 mRNA

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member B1

decreases response to substance

ALDH3B1 protein results in decreased susceptibility to Vitamin K 3

NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921

G

aldehyde dehydrogenase 6 family, member A1

affects expression

Vitamin K 3 affects the expression of ALDH6A1 mRNA

NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656

G

alkaline phosphatase, biomineralization associated

decreases secretion

Vitamin K 3 results in decreased secretion of ALPL protein

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

Aly/REF export factor

affects expression

Vitamin K 3 affects the expression of ALYREF mRNA

NCBI chr10:105,871,424...105,875,076
Ensembl chr10:105,871,306...105,875,069

G

angiomotin like 2

affects expression

Vitamin K 3 affects the expression of AMOTL2 mRNA

NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910

G

anaphase promoting complex subunit 1

affects expression

Vitamin K 3 affects the expression of ANAPC1 mRNA

NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273

G

angiogenin

affects expression

Vitamin K 3 affects the expression of ANG mRNA

NCBI chr15:24,312,711...24,323,361

G

ankyrin 3

affects expression

Vitamin K 3 affects the expression of ANK3 mRNA

NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300

G

ankyrin repeat family A member 2

affects expression

Vitamin K 3 affects the expression of ANKRA2 mRNA

NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730

G

ankyrin repeat domain containing 11

affects expression

Vitamin K 3 affects the expression of ANKRD11 mRNA

NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962

G

ankyrin repeat domain 37

decreases expression

Vitamin K 3 results in decreased expression of ANKRD37 mRNA

NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963

G

ankyrin repeat and sterile alpha motif domain containing 1A

affects expression

Vitamin K 3 affects the expression of ANKS1 mRNA

NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148

G

ankyrin repeat and sterile alpha motif domain containing 6

affects expression

Vitamin K 3 affects the expression of ANKS6 mRNA

NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596

G

acidic nuclear phosphoprotein 32 family member B

affects expression

Vitamin K 3 affects the expression of ANP32B mRNA

NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717

G

adenine nucleotide translocase lysine methyltransferase

affects expression

Vitamin K 3 affects the expression of ANTKMT mRNA

NCBI chr10:14,812,274...14,814,798
Ensembl chr10:14,812,269...14,814,193

G

annexin A13

affects expression

Vitamin K 3 affects the expression of ANXA13 mRNA

NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907

G

aldehyde oxidase 1

multiple interactions
decreases activity

Vitamin K 3 inhibits the reaction [AOX1 protein results in increased metabolism of zoniporide]
Vitamin K 3 results in decreased activity of AOX1 protein

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

amyloid beta precursor protein binding family B member 2

affects expression

Vitamin K 3 affects the expression of APBB2 mRNA

NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases response to substance

APEX1 gene mutant form results in increased susceptibility to Vitamin K 3

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

amyloid beta precursor like protein 2

affects expression

Vitamin K 3 affects the expression of APLP2 mRNA

NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855

G

apolipoprotein A1

affects expression

Vitamin K 3 affects the expression of APOA1 mRNA

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein A5

affects expression

Vitamin K 3 affects the expression of APOA5 mRNA

NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816

G

apolipoprotein C3

affects expression

Vitamin K 3 affects the expression of APOC3 mRNA

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein E

affects response to substance

APOE protein affects the susceptibility to Vitamin K 3

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

apolipoprotein H

affects expression

Vitamin K 3 affects the expression of APOH mRNA

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

G

aquaporin 11

affects expression

Vitamin K 3 affects the expression of AQP11 mRNA

NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725

G

amphiregulin

increases expression

Vitamin K 3 results in increased expression of AREG mRNA

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

arginase 2

affects expression

Vitamin K 3 affects the expression of ARG2 mRNA

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho guanine nucleotide exchange factor 7

affects expression

Vitamin K 3 affects the expression of ARHGEF7 mRNA

NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697

G

AT-rich interaction domain 3A

affects expression

Vitamin K 3 affects the expression of ARID3A mRNA

PMID:20044591 PMID:23410634

NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599

G

AT-rich interaction domain 5A

affects expression

Vitamin K 3 affects the expression of ARID5A mRNA

NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597

G

armadillo repeat containing, X-linked 1

decreases expression

Vitamin K 3 results in decreased expression of ARMCX1 mRNA

NCBI chr X:97,898,969...97,902,874
Ensembl chr X:97,898,883...97,903,299

G

arrestin domain containing 2

affects expression

Vitamin K 3 affects the expression of ARRDC2 mRNA

NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029

G

anti-silencing function 1A histone chaperone

increases expression

Vitamin K 3 results in increased expression of ASF1A mRNA

NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808

G

acid sensing ion channel subunit 1

decreases expression

Vitamin K 3 results in decreased expression of ASIC1 mRNA

NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541

G

activating transcription factor 3

affects expression
increases expression

Vitamin K 3 affects the expression of ATF3 mRNA
Vitamin K 3 results in increased expression of ATF3 mRNA

PMID:12414654 PMID:20044591

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 6

multiple interactions
increases expression

Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of ATF6 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of ATF6 protein]

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 5

affects response to substance

ATG5 mRNA affects the susceptibility to Vitamin K 3
ATG5 protein affects the susceptibility to Vitamin K 3

PMID:18073215 PMID:18319638 PMID:20578144

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

affects expression

Vitamin K 3 affects the expression of ATIC mRNA

NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889

G

antioxidant 1 copper chaperone

affects expression

Vitamin K 3 affects the expression of ATOX1 mRNA

NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950

G

ATP synthase inhibitory factor subunit 1

affects expression

Vitamin K 3 affects the expression of ATP5IF1 mRNA

NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668

G

ATP synthase peripheral stalk subunit OSCP

affects expression

Vitamin K 3 affects the expression of ATP5PO mRNA

NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592

G

ATPase copper transporting beta

affects expression

Vitamin K 3 affects the expression of ATP7B mRNA

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

attractin

affects expression

Vitamin K 3 affects the expression of ATRN mRNA

NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322

G

ATRX, chromatin remodeler

affects expression

Vitamin K 3 affects the expression of ATRX mRNA

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

ataxin 2-like

affects expression

Vitamin K 3 affects the expression of ATXN2L mRNA

NCBI chr 1:181,078,293...181,090,079
Ensembl chr 1:181,078,288...181,089,686

G

AU RNA binding methylglutaconyl-CoA hydratase

affects expression

Vitamin K 3 affects the expression of AUH mRNA

NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896

G

aurora kinase B

decreases expression

Vitamin K 3 results in decreased expression of AURKB mRNA

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

G

activator of transcription and developmental regulator AUTS2

affects expression

Vitamin K 3 affects the expression of AUTS2 mRNA

NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416

G

Beta-1,3-galactosyltransferase 6

affects expression

Vitamin K 3 affects the expression of B3GALT6 mRNA

NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338

G

bromo adjacent homology domain containing 1

affects expression

Vitamin K 3 affects the expression of BAHD1 mRNA

NCBI chr 3:105,891,207...105,914,414
Ensembl chr 3:105,892,478...105,914,410

G

BCL2-antagonist/killer 1

affects expression

Vitamin K 3 affects the expression of BAK1 mRNA

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

BMP and activin membrane-bound inhibitor

affects expression

Vitamin K 3 affects the expression of BAMBI mRNA

NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060

G

basic leucine zipper ATF-like transcription factor

increases expression

Vitamin K 3 results in increased expression of BATF mRNA

NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051

G

BCL2 associated X, apoptosis regulator

affects localization
increases expression
multiple interactions

Vitamin K 3 affects the localization of BAX protein
Vitamin K 3 results in increased expression of BAX protein
EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of BAX protein]

PMID:15961378 PMID:25005833

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

affects expression

Vitamin K 3 affects the expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

Bardet-Biedl syndrome 2

affects expression

Vitamin K 3 affects the expression of BBS2 mRNA

NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993

G

BCAR3 adaptor protein, NSP family member

affects expression

Vitamin K 3 affects the expression of BCAR3 mRNA

NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798

G

brain enriched myelin associated protein 1

affects expression

Vitamin K 3 affects the expression of BCAS1 mRNA

NCBI chr 3:159,136,077...159,219,072
Ensembl chr 3:159,136,083...159,219,106

G

BCL2, apoptosis regulator

multiple interactions
decreases expression

[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 protein]
Vitamin K 3 results in decreased expression of BCL2 mRNA; Vitamin K 3 results in decreased expression of BCL2 protein
Acetaminophen inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in decreased expression of BCL2 protein]

PMID:19082730 PMID:19265712 PMID:25005833

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL6, transcription repressor

affects expression

Vitamin K 3 affects the expression of BCL6 mRNA

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

BCL9 like

decreases expression

Vitamin K 3 results in decreased expression of BCL9L protein

NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611

G

3-hydroxybutyrate dehydrogenase 2

affects expression

Vitamin K 3 affects the expression of BDH2 mRNA

NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072

G

beclin 1

affects expression

Vitamin K 3 affects the expression of BECN1 mRNA

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

Bet1 golgi vesicular membrane trafficking protein-like

affects expression

Vitamin K 3 affects the expression of BET1L mRNA

NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040

G

bone gamma-carboxyglutamate protein

decreases expression
increases secretion
increases expression
multiple interactions

Vitamin K 3 results in decreased expression of BGLAP mRNA
Vitamin K 3 results in increased secretion of BGLAP protein
Vitamin K 3 results in increased expression of BGLAP protein modified form
Vitamin K 3 inhibits the reaction [Estrogens deficiency results in decreased secretion of BGLAP protein]

PMID:19675304 PMID:30453296

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

BCL2-interacting killer

increases expression

Vitamin K 3 results in increased expression of BIK mRNA

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

baculoviral IAP repeat-containing 5

affects expression

Vitamin K 3 affects the expression of BIRC5 mRNA

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

biliverdin reductase B

increases expression

Vitamin K 3 results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

BMS1 ribosome biogenesis factor

affects expression

Vitamin K 3 affects the expression of BMS1 mRNA

NCBI chr 4:151,558,163...151,595,187
Ensembl chr 4:151,558,163...151,595,127

G

BCL2 interacting protein 3

decreases expression

Vitamin K 3 results in decreased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

bromodomain containing 8

affects expression

Vitamin K 3 affects the expression of BRD8 mRNA

NCBI chr18:26,204,892...26,229,999
Ensembl chr18:26,181,732...26,229,884

G

BRMS1, transcriptional repressor and anoikis regulator

affects expression

Vitamin K 3 affects the expression of BRMS1 mRNA

NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028

G

BTG anti-proliferation factor 2

increases expression

Vitamin K 3 results in increased expression of BTG2 mRNA

PMID:12414654 PMID:21382384

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

BUB1 mitotic checkpoint serine/threonine kinase

affects expression

Vitamin K 3 affects the expression of BUB1 mRNA

PMID:20044591 PMID:23410634

NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650

G

BUD13 homolog

affects expression

Vitamin K 3 affects the expression of BUD13 mRNA

NCBI chr 8:46,575,124...46,590,964
Ensembl chr 8:46,575,115...46,590,958

G

similar to human chromosome 17 open reading frame 100

affects expression

Vitamin K 3 affects the expression of C17ORF100 mRNA

NCBI chr10:56,840,451...56,843,674
Ensembl chr10:56,832,412...56,843,871

G

similar to human chromosome 3 open reading frame 52

affects expression

Vitamin K 3 affects the expression of C3ORF52 mRNA

NCBI chr11:55,166,986...55,192,273
Ensembl chr11:55,166,678...55,192,292

G

similar to human chromosome 6 open reading frame 62

affects expression

Vitamin K 3 affects the expression of C6ORF62 mRNA

NCBI chr17:40,256,211...40,267,851
Ensembl chr17:40,256,211...40,276,020

G

C1GALT1-specific chaperone 1

affects expression

Vitamin K 3 affects the expression of C1GALT1C1 mRNA

NCBI chr X:117,378,123...117,382,620
Ensembl chr X:117,375,525...117,382,787

G

complement C1q binding protein

affects expression

Vitamin K 3 affects the expression of C1QBP mRNA

NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649

G

C2 calcium-dependent domain containing 5

affects expression

Vitamin K 3 affects the expression of C2CD5 mRNA

NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558

G

similar to human chromosome 8 open reading frame 76

affects expression

Vitamin K 3 affects the expression of C8ORF76 mRNA

NCBI chr 7:89,558,890...89,569,810
Ensembl chr 7:89,558,909...89,569,810

G

similar to human chromosome 15 open reading frame 39

affects expression

Vitamin K 3 affects the expression of C15ORF39 mRNA

NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941

G

Cdk5 and Abl enzyme substrate 1

affects expression

Vitamin K 3 affects the expression of CABLES1 mRNA

NCBI chr18:3,076,556...3,181,181
Ensembl chr18:3,075,524...3,181,181

G

calcium voltage-gated channel subunit alpha1 G

affects expression

Vitamin K 3 affects the expression of CACNA1G mRNA

NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752

G

calbindin 1

increases expression

Vitamin K 3 results in increased expression of CALB1 mRNA

NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

affects expression

Vitamin K 3 affects the expression of CAMK2N1 mRNA

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

G

calnexin

affects expression

Vitamin K 3 affects the expression of CANX mRNA

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

calpain 2

affects expression

Vitamin K 3 affects the expression of CAPN2 mRNA

NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969

G

carbonic anhydrase 12

affects expression

Vitamin K 3 affects the expression of CA12 mRNA

NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440

G

caspase 2

increases expression

Vitamin K 3 results in increased expression of CASP2 protein modified form

NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379

G

caspase 3

multiple interactions
increases activity
increases cleavage
increases expression

[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein]; Vitamin K 3 analog inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Vitamin K 3 analog promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]
Vitamin K 3 results in increased activity of CASP3 protein
Vitamin K 3 results in increased cleavage of CASP3 protein
Buthionine Sulfoximine promotes the reaction [Vitamin K 3 results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP3 protein]; U 0126 promotes the reaction [Vitamin K 3 results in increased activity of CASP3 protein]
Vitamin K 3 results in increased expression of CASP3 protein modified form

PMID:12965111 PMID:16310883 PMID:19082730 PMID:20829426 PMID:23300732 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 4

multiple interactions

[Metyrapone co-treated with Vitamin K 3] affects the localization of CASP4 protein; [S 3483 co-treated with Vitamin K 3] affects the localization of CASP4 protein

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 6

multiple interactions
increases cleavage

pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased activity of CASP6 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP6 protein]

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 9

multiple interactions
increases cleavage

[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein]; EUK-134 inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP9 protein]; Vitamin K 3 analog promotes the reaction [Doxorubicin results in increased activity of CASP9 protein]
pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased cleavage of CASP9 protein]

PMID:16310883 PMID:19082730 PMID:25005833 PMID:29141199

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

affects expression
decreases activity
decreases response to substance
multiple interactions

Vitamin K 3 affects the expression of CAT mRNA
Vitamin K 3 results in decreased activity of CAT protein
CAT protein results in decreased susceptibility to Vitamin K 3
[CAT protein co-treated with SOD1 protein] results in decreased susceptibility to Vitamin K 3; [CAT protein co-treated with SOD2 protein] results in decreased susceptibility to Vitamin K 3; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid]

PMID:12633745 PMID:14698046 PMID:15331536 PMID:20044591 PMID:21689642 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolae associated protein 2

affects expression

Vitamin K 3 affects the expression of CAVIN2 mRNA

NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147

G

core-binding factor subunit beta

affects expression

Vitamin K 3 affects the expression of CBFB mRNA

NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751

G

carbonyl reductase 1

multiple interactions
increases metabolic processing

[S-Nitrosoglutathione binds to CBR1 protein] inhibits the reaction [CBR1 protein results in increased metabolism of Vitamin K 3]; Vitamin K 3 inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]

PMID:11306090 PMID:19061875 PMID:23295225

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

carbonyl reductase 3

affects metabolic processing
increases expression

CBR3 protein affects the metabolism of Vitamin K 3
Vitamin K 3 results in increased expression of CBR3 mRNA

PMID:20007405 PMID:21382384 PMID:25270620

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

cell cycle and apoptosis regulator 2

affects expression

Vitamin K 3 affects the expression of CCAR2 mRNA

NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636

G

coiled-coil domain containing 12

affects expression

Vitamin K 3 affects the expression of CCDC12 mRNA

NCBI chr 8:110,635,276...110,686,417
Ensembl chr 8:110,635,710...110,686,417

G

coiled-coil domain containing 125

affects expression

Vitamin K 3 affects the expression of CCDC125 mRNA

NCBI chr 2:31,809,120...31,835,538
Ensembl chr 2:31,809,228...31,850,152

G

coiled-coil domain containing 136

decreases expression

Vitamin K 3 results in decreased expression of CCDC136 mRNA

NCBI chr 4:57,997,825...58,027,598
Ensembl chr 4:57,997,853...58,027,646

G

coiled-coil domain containing 88B

affects expression

Vitamin K 3 affects the expression of CCDC88B mRNA

NCBI chr 1:204,036,913...204,052,878
Ensembl chr 1:204,036,918...204,052,970

G

coiled-coil domain containing 90B

affects expression

Vitamin K 3 affects the expression of CCDC90B mRNA

NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338

G

C-C motif chemokine ligand 3

multiple interactions
increases secretion
increases expression

Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL3 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL3 protein]

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 5

multiple interactions
increases secretion
increases expression

Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL5 mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL5 protein]

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cellular communication network factor 1

increases expression

Vitamin K 3 results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

affects expression

Vitamin K 3 affects the expression of CCN2 mRNA

PMID:20044591 PMID:23410634

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin A2

decreases expression
affects expression

Vitamin K 3 results in decreased expression of CCNA2 mRNA
Vitamin K 3 affects the expression of CCNA2 mRNA

PMID:12414654 PMID:23410634

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B2

affects expression

Vitamin K 3 affects the expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

affects expression
decreases expression

Vitamin K 3 affects the expression of CCND1 mRNA
Vitamin K 3 results in decreased expression of CCND1 protein

PMID:20044591 PMID:31238027

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin E1

affects expression

Vitamin K 3 affects the expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin G1

affects expression

Vitamin K 3 affects the expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

cyclin I

affects expression

Vitamin K 3 affects the expression of CCNI mRNA

NCBI chr14:14,879,698...14,902,510
Ensembl chr14:14,879,717...14,902,510

G

cyclin J-like

affects expression

Vitamin K 3 affects the expression of CCNJL mRNA

NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426

G

cyclin Q

affects expression

Vitamin K 3 affects the expression of CCNQ mRNA

NCBI chr10:63,646,532...63,647,695
Ensembl chr10:63,646,527...63,647,961

G

chaperonin containing TCP1 subunit 2

affects expression

Vitamin K 3 affects the expression of CCT2 mRNA

NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944

G

chaperonin containing TCP1 subunit 5

affects expression

Vitamin K 3 affects the expression of CCT5 mRNA

NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930

G

CD1d1 molecule

affects expression

Vitamin K 3 affects the expression of CD1D mRNA

NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089

G

CD36 molecule

affects expression

Vitamin K 3 affects the expression of CD36 mRNA

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD44 molecule

affects expression

Vitamin K 3 affects the expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

Cd48 molecule

affects expression

Vitamin K 3 affects the expression of CD48 mRNA

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

CD74 molecule

affects expression

Vitamin K 3 affects the expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

CD9 molecule

affects expression

Vitamin K 3 affects the expression of CD9 mRNA

PMID:20044591 PMID:23410634

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cell division cycle 14B

affects expression

Vitamin K 3 affects the expression of CDC14B mRNA

NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235

G

CDC42 effector protein 4

affects expression

Vitamin K 3 affects the expression of CDC42EP4 mRNA

NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695

G

cell division cycle 45

affects expression

Vitamin K 3 affects the expression of CDC45 mRNA

NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619

G

cell division cycle associated 5

affects expression

Vitamin K 3 affects the expression of CDCA5 mRNA

NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023

G

cell division cycle associated 7

affects expression

Vitamin K 3 affects the expression of CDCA7 mRNA

NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353

G

cadherin 1

increases expression

Vitamin K 3 results in increased expression of CDH1 protein

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 16

affects expression

Vitamin K 3 affects the expression of CDH16 mRNA

NCBI chr19:360,824...371,008
Ensembl chr19:360,824...371,007

G

cadherin 2

decreases expression

Vitamin K 3 results in decreased expression of CDH2 protein

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cyclin-dependent kinase 4

decreases expression

Vitamin K 3 results in decreased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
increases expression

[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein; EUK-134 affects the reaction [Vitamin K 3 results in increased expression of CDKN1A protein]; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein]
Vitamin K 3 results in increased expression of CDKN1A mRNA; Vitamin K 3 results in increased expression of CDKN1A protein

PMID:12414654 PMID:19082730 PMID:23410634 PMID:25005833

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

multiple interactions

[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein]

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 1C

affects expression

Vitamin K 3 affects the expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

increases expression

Vitamin K 3 results in increased expression of CDKN2A mRNA

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

chromatin licensing and DNA replication factor 1

affects expression

Vitamin K 3 affects the expression of CDT1 mRNA

NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659

G

caudal type homeo box 1

increases expression

Vitamin K 3 results in increased expression of CDX1 mRNA

NCBI chr18:54,472,587...54,490,913
Ensembl chr18:54,473,444...54,490,814

G

CCAAT/enhancer binding protein alpha

affects expression

Vitamin K 3 affects the expression of CEBPA mRNA

PMID:20044591 PMID:23410634

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

centromere protein A

decreases expression

Vitamin K 3 results in decreased expression of CENPA mRNA

NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675

G

centromere protein F

affects expression

Vitamin K 3 affects the expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

centrosomal protein 95

affects expression

Vitamin K 3 affects the expression of CEP95 mRNA

NCBI chr10:91,732,111...91,760,095
Ensembl chr10:91,732,111...91,760,092

G

cilia and flagella associated protein 20

affects expression

Vitamin K 3 affects the expression of CFAP20 mRNA

NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558

G

cingulin-like 1

affects expression

Vitamin K 3 affects the expression of CGNL1 mRNA

NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917

G

checkpoint kinase 1

decreases expression

Vitamin K 3 results in decreased expression of CHEK1 mRNA

NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009

G

choline kinase alpha

affects expression

Vitamin K 3 affects the expression of CHKA mRNA

PMID:20044591 PMID:23410634

NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516

G

chondroitin polymerizing factor 2

increases expression

Vitamin K 3 results in increased expression of CHPF2 mRNA

NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916

G

carbohydrate sulfotransferase 15

affects expression

Vitamin K 3 affects the expression of CHST15 mRNA

NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707

G

carbohydrate sulfotransferase 7

affects expression

Vitamin K 3 affects the expression of CHST7 mRNA

NCBI chr X:2,396,260...2,432,828
Ensembl chr X:2,393,874...2,432,840

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

affects expression

Vitamin K 3 affects the expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

cytoskeleton associated protein 5

affects expression

Vitamin K 3 affects the expression of CKAP5 mRNA

NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264

G

creatine kinase B

affects expression

Vitamin K 3 affects the expression of CKB mRNA

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

CDC28 protein kinase regulatory subunit 1B

affects expression

Vitamin K 3 affects the expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

claudin 23

affects expression

Vitamin K 3 affects the expression of CLDN23 mRNA

NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523

G

claudin 3

affects expression

Vitamin K 3 affects the expression of CLDN3 mRNA

NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001

G

CAP-GLY domain containing linker protein 1

affects expression

Vitamin K 3 affects the expression of CLIP1 mRNA

NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884

G

ClpB family mitochondrial disaggregase

affects expression

Vitamin K 3 affects the expression of CLPB mRNA

NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788

G

carboxymethylenebutenolidase homolog

affects expression

Vitamin K 3 affects the expression of CMBL mRNA

NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009

G

c-Maf-inducing protein

affects expression

Vitamin K 3 affects the expression of CMIP mRNA

NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709

G

CKLF-like MARVEL transmembrane domain containing 3

affects expression

Vitamin K 3 affects the expression of CMTM3 mRNA

NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790

G

contactin associated protein 2

affects expression

Vitamin K 3 affects the expression of CNTNAP2 mRNA

NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027

G

cytochrome c oxidase assembly factor 4 homolog

affects expression

Vitamin K 3 affects the expression of COA4 mRNA

NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174

G

cytochrome C oxidase assembly factor 5

affects expression

Vitamin K 3 affects the expression of COA5 mRNA

NCBI chr 9:39,651,459...39,664,870

G

collagen type I alpha 1 chain

decreases expression

Vitamin K 3 results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type V alpha 2 chain

affects expression

Vitamin K 3 affects the expression of COL5A2 mRNA

NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154

G

coronin 2A

affects expression

Vitamin K 3 affects the expression of CORO2A mRNA

NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035

G

cAMP responsive element binding protein 1

multiple interactions

[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of CREB1 protein

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cysteine rich protein 1

affects expression

Vitamin K 3 affects the expression of CRIP1 mRNA

NCBI chr 6:132,226,746...132,234,620
Ensembl chr 6:132,226,746...132,234,620

G

crystallin, lambda 1

affects expression

Vitamin K 3 affects the expression of CRYL1 mRNA

NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997

G

C-terminal binding protein 2

affects expression

Vitamin K 3 affects the expression of CTBP2 mRNA

NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222

G

cardiotrophin 1

multiple interactions
increases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; 2-methoxyestradiol inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; acetovanillone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; diphenyleneiodonium inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; pyrazolanthrone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]
Vitamin K 3 results in increased expression of CTF1 mRNA; Vitamin K 3 results in increased expression of CTF1 protein

NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335

G

catenin beta 1

decreases expression

Vitamin K 3 results in decreased expression of CTNNB1 protein

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

catenin delta 1

affects expression

Vitamin K 3 affects the expression of CTNND1 mRNA

NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516

G

CTP synthase 1

affects expression

Vitamin K 3 affects the expression of CTPS1 mRNA

NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180

G

CTR9 homolog, Paf1/RNA polymerase II complex component

affects expression

Vitamin K 3 affects the expression of CTR9 mRNA

NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303

G

cullin 4A

affects expression

Vitamin K 3 affects the expression of CUL4A mRNA

NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330

G

CXXC finger protein 5

affects expression

Vitamin K 3 affects the expression of CXXC5 mRNA

NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673

G

cytochrome b5 domain containing 2

affects expression

Vitamin K 3 affects the expression of CYB5D2 mRNA

NCBI chr10:57,394,268...57,413,336
Ensembl chr10:57,396,765...57,413,715

G

cytochrome b5 reductase 1

affects expression

Vitamin K 3 affects the expression of CYB5R1 mRNA

NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458

G

cytochrome b-245 alpha chain

increases expression

Vitamin K 3 results in increased expression of CYBA protein

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
increases activity
increases expression

Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Vitamin K 3 results in increased activity of CYP1A1 protein
Vitamin K 3 results in increased expression of CYP1A1 mRNA

PMID:15603920 PMID:18493746

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions
increases expression
increases activity

Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Vitamin K 3 results in increased expression of CYP1A2 mRNA
Vitamin K 3 results in increased activity of CYP1A2 protein

PMID:15603920 PMID:18493746

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

Vitamin K 3 results in increased expression of CYP1B1 mRNA

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 24, subfamily a, polypeptide 1

affects expression

Vitamin K 3 affects the expression of CYP24A1 mRNA

NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression
multiple interactions

Vitamin K 3 results in decreased expression of CYP2E1 mRNA
[CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein; Buthionine Sulfoximine promotes the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Dicumarol inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; S-ethyl glutathione inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]

PMID:22486562 PMID:25270620

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 2, subfamily j, polypeptide 4

affects expression

Vitamin K 3 affects the expression of CYP2J9 mRNA

NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 2, subfamily r, polypeptide 1

affects expression

Vitamin K 3 affects the expression of CYP2R1 mRNA

NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759

G

diazepam binding inhibitor

affects expression

Vitamin K 3 affects the expression of DBI mRNA

NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693

G

decapping mRNA 1B

affects expression

Vitamin K 3 affects the expression of DCP1B mRNA

NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145

G

dicarbonyl and L-xylulose reductase

multiple interactions
increases metabolic processing
decreases activity

[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide; [DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Superoxides; [Vitamin K 3 co-treated with NADP] binds to DCXR protein; CAT protein inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide]; Diacetyl inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Superoxides]; Vitamin K 3 inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]
Vitamin K 3 results in decreased activity of DCXR protein

PMID:25526675 PMID:28595002

NCBI chr10:106,006,404...106,008,293

G

dopa decarboxylase

affects expression

Vitamin K 3 affects the expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

Vitamin K 3 results in increased expression of DDIT3 mRNA; Vitamin K 3 results in increased expression of DDIT3 protein
Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of DDIT3 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of DDIT3 protein]

PMID:12414654 PMID:19819344

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

affects expression

Vitamin K 3 affects the expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DNA-damage-inducible transcript 4-like

increases expression

Vitamin K 3 results in increased expression of DDIT4L mRNA

NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375

G

DEAD-box helicase 1

affects expression

Vitamin K 3 affects the expression of DDX1 mRNA

NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365

G

DEAD-box helicase 23

affects expression

Vitamin K 3 affects the expression of DDX23 mRNA

NCBI chr 7:129,797,620...129,814,909
Ensembl chr 7:129,797,614...129,814,949

G

DEAD-box helicase 42

increases expression

Vitamin K 3 results in increased expression of DDX42 mRNA

NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939

G

DEAD-box helicase 47

affects expression

Vitamin K 3 affects the expression of DDX47 mRNA

NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115

G

defensin beta 1

affects expression

Vitamin K 3 affects the expression of DEFB1 mRNA

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

G

DEP domain containing 7

affects expression

Vitamin K 3 affects the expression of DEPDC7 mRNA

NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124

G

DEP domain containing MTOR-interacting protein

affects expression

Vitamin K 3 affects the expression of DEPTOR mRNA

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

G

desumoylating isopeptidase 2

affects expression

Vitamin K 3 affects the expression of DESI2 mRNA

NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416

G

diacylglycerol O-acyltransferase 1

affects expression

Vitamin K 3 affects the expression of DGAT1 mRNA

NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299

G

diacylglycerol O-acyltransferase 2

affects expression

Vitamin K 3 affects the expression of DGAT2 mRNA

PMID:20044591 PMID:23410634

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

diacylglycerol kinase, delta

affects expression

Vitamin K 3 affects the expression of DGKD mRNA

NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345

G

dehydrogenase/reductase 11

increases reduction

DHRS11 protein results in increased reduction of Vitamin K 3

NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295

G

DEAH-box helicase 35

affects expression

Vitamin K 3 affects the expression of DHX35 mRNA

NCBI chr 3:147,450,178...147,507,473
Ensembl chr 3:147,450,163...147,507,451

G

DExH-box helicase 9

affects expression

Vitamin K 3 affects the expression of DHX9 mRNA

NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069

G

divergent protein kinase domain 1B

affects expression

Vitamin K 3 affects the expression of DIPK1B mRNA

NCBI chr 3:9,455,914...9,464,169
Ensembl chr 3:9,456,409...9,464,161

G

dyskerin pseudouridine synthase 1

affects expression

Vitamin K 3 affects the expression of DKC1 mRNA

G

dickkopf WNT signaling pathway inhibitor 1

affects expression
increases expression

Vitamin K 3 affects the expression of DKK1 mRNA
Vitamin K 3 results in increased expression of DKK1 mRNA

PMID:12414654 PMID:20044591

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

DLG associated protein 5

affects expression

Vitamin K 3 affects the expression of DLGAP5 mRNA

PMID:20044591 PMID:23410634

NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518

G

dystrophin

increases response to substance

DMD gene mutant form results in increased susceptibility to Vitamin K 3

NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207

G

doublesex and mab-3 related transcription factor 1

increases expression

Vitamin K 3 results in increased expression of DMRT1 mRNA

NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333

G

DnaJ heat shock protein family (Hsp40) member B1

affects expression

Vitamin K 3 affects the expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member C14

affects expression

Vitamin K 3 affects the expression of DNAJC14 mRNA

NCBI chr 7:1,233,856...1,247,349
Ensembl chr 7:1,235,162...1,248,645

G

dynamin 1-like

affects expression

Vitamin K 3 affects the expression of DNM1L mRNA

NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482

G

DNA methyltransferase 3 beta

affects expression

Vitamin K 3 affects the expression of DNMT3B mRNA

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

DNA methyltransferase 3 like

decreases expression

Vitamin K 3 results in decreased expression of DNMT3L mRNA

NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516

G

diphthamide biosynthesis 1

affects expression

Vitamin K 3 affects the expression of DPH1 mRNA

NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850

G

diphthamide biosynthesis 3

affects expression

Vitamin K 3 affects the expression of DPH3 mRNA

NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265

G

dolichyl-phosphate mannosyltransferase subunit 3, regulatory

affects expression

Vitamin K 3 affects the expression of DPM3 mRNA

NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668

G

dihydropyrimidine dehydrogenase

affects expression

Vitamin K 3 affects the expression of DPYD mRNA

NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982

G

dual specificity phosphatase 1

affects expression
decreases expression

Vitamin K 3 affects the expression of DUSP1 mRNA
Vitamin K 3 results in decreased expression of DUSP1 mRNA

PMID:23410634 PMID:25270620

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 2

affects expression

Vitamin K 3 affects the expression of DUSP2 mRNA

NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499

G

dual specificity phosphatase 3

affects expression

Vitamin K 3 affects the expression of DUSP3 mRNA

NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962

G

dual specificity phosphatase 6

affects expression

Vitamin K 3 affects the expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dual specificity phosphatase 9

affects expression

Vitamin K 3 affects the expression of DUSP9 mRNA

NCBI chr X:151,351,897...151,355,822
Ensembl chr X:151,351,897...151,355,821

G

dynein cytoplasmic 1 heavy chain 1

affects expression

Vitamin K 3 affects the expression of DYNC1H1 mRNA

NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883

G

dynein, cytoplasmic 1 light intermediate chain 2

affects expression

Vitamin K 3 affects the expression of DYNC1LI2 mRNA

NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670

G

dual specificity tyrosine phosphorylation regulated kinase 2

affects expression

Vitamin K 3 affects the expression of DYRK2 mRNA

NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106

G

E2F transcription factor 1

affects expression

Vitamin K 3 affects the expression of E2F1 mRNA

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 3

affects expression

Vitamin K 3 affects the expression of E2F3 mRNA

NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253

G

EBNA1 binding protein 2

affects expression

Vitamin K 3 affects the expression of EBNA1BP2 mRNA

NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267

G

Ecm29 proteasome adaptor and scaffold

affects expression

Vitamin K 3 affects the expression of ECPAS mRNA

NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860

G

enhancer of mRNA decapping 3

affects expression

Vitamin K 3 affects the expression of EDC3 mRNA

NCBI chr 8:58,106,147...58,151,685
Ensembl chr 8:58,106,175...58,151,671

G

endothelin 1

increases expression
affects expression

Vitamin K 3 results in increased expression of EDN1 mRNA
Vitamin K 3 affects the expression of EDN1 mRNA

PMID:12414654 PMID:20044591 PMID:23410634

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

ephrin B2

decreases expression

Vitamin K 3 results in decreased expression of EFNB2 mRNA

NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391

G

epidermal growth factor receptor

increases phosphorylation

Vitamin K 3 results in increased phosphorylation of EGFR protein

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

egl-9 family hypoxia-inducible factor 3

decreases expression

Vitamin K 3 results in decreased expression of EGLN3 mRNA

NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766

G

early growth response 1

increases expression
affects expression

Vitamin K 3 results in increased expression of EGR1 mRNA
Vitamin K 3 affects the expression of EGR1 mRNA

PMID:12414654 PMID:20044591 PMID:23410634

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

euchromatic histone lysine methyltransferase 1

affects expression

Vitamin K 3 affects the expression of EHMT1 mRNA

NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007

G

eukaryotic translation initiation factor 3, subunit C

affects expression

Vitamin K 3 affects the expression of EIF3C mRNA

NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493

G

eukaryotic translation initiation factor 3, subunit J

affects expression

Vitamin K 3 affects the expression of EIF3J mRNA

NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953

G

eukaryotic translation initiation factor 4A1

affects expression

Vitamin K 3 affects the expression of EIF4A1 mRNA

NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858

G

eukaryotic translation initiation factor 4B

affects expression

Vitamin K 3 affects the expression of EIF4B mRNA

NCBI chr 7:133,206,637...133,228,436

G

eukaryotic translation initiation factor 4E nuclear import factor 1

affects expression

Vitamin K 3 affects the expression of EIF4ENIF1 mRNA

NCBI chr14:78,056,115...78,099,846
Ensembl chr14:78,056,297...78,098,793

G

eukaryotic translation initiation factor 4, gamma 2

affects expression

Vitamin K 3 affects the expression of EIF4G2 mRNA

NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588

G

ELAV like RNA binding protein 1

multiple interactions
increases phosphorylation

[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]; [[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]; [Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein; JAK3 protein promotes the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]; Janus Kinase Inhibitors inhibits the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]]

NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784

G

ELAV like RNA binding protein 2

affects expression

Vitamin K 3 affects the expression of ELAVL2 mRNA

NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097

G

elongation factor 1

affects expression

Vitamin K 3 affects the expression of ELOF1 mRNA

NCBI chr 8:20,645,336...20,650,888
Ensembl chr 8:20,645,336...20,650,579

G

EMG1 N1-specific pseudouridine methyltransferase

affects expression

Vitamin K 3 affects the expression of EMG1 mRNA

NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540

G

elastin microfibril interfacer 1

affects expression

Vitamin K 3 affects the expression of EMILIN1 mRNA

NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698

G

epithelial membrane protein 2

affects expression

Vitamin K 3 affects the expression of EMP2 mRNA

NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733

G

ectodermal-neural cortex 1

affects expression

Vitamin K 3 affects the expression of ENC1 mRNA

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

enolase superfamily member 1

affects expression

Vitamin K 3 affects the expression of ENOSF1 mRNA

NCBI chr 9:113,275,267...113,314,842

G

ectonucleotide pyrophosphatase/phosphodiesterase 3

decreases expression

Vitamin K 3 results in decreased expression of ENPP3 mRNA

NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041

G

E1A binding protein p300

decreases expression

Vitamin K 3 results in decreased expression of EP300 protein

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

endothelial PAS domain protein 1

affects expression

Vitamin K 3 affects the expression of EPAS1 mRNA

NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228

G

epoxide hydrolase 1

increases expression

Vitamin K 3 results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

epsin 2

affects expression

Vitamin K 3 affects the expression of EPN2 mRNA

NCBI chr10:46,197,785...46,259,673
Ensembl chr10:46,197,785...46,259,642

G

epsin 3

affects expression

Vitamin K 3 affects the expression of EPN3 mRNA

NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356

G

erythropoietin

multiple interactions

[Vitamin K 3 results in increased abundance of Hydrogen Peroxide] which results in decreased expression of EPO protein

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

G

glutamyl-prolyl-tRNA synthetase 1

affects expression

Vitamin K 3 affects the expression of EPRS1 mRNA

NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966

G

EPS8-like 2

affects expression

Vitamin K 3 affects the expression of EPS8L2 mRNA

NCBI chr 1:196,446,260...196,471,544
Ensembl chr 1:196,446,287...196,471,541

G

erb-b2 receptor tyrosine kinase 3

affects expression

Vitamin K 3 affects the expression of ERBB3 mRNA

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

erbb2 interacting protein

affects expression

Vitamin K 3 affects the expression of ERBIN mRNA

NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852

G

estrogen receptor 1

affects binding
multiple interactions

Vitamin K 3 binds to ESR1 protein
Vitamin K 3 inhibits the reaction [Estradiol binds to ESR1 protein]

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

epithelial splicing regulatory protein 1

affects expression

Vitamin K 3 affects the expression of ESRP1 mRNA

NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062

G

epithelial splicing regulatory protein 2

affects expression

Vitamin K 3 affects the expression of ESRP2 mRNA

NCBI chr19:34,034,559...34,041,726
Ensembl chr19:34,034,559...34,041,726

G

extended synaptotagmin 2

affects expression

Vitamin K 3 affects the expression of ESYT2 mRNA

NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590

G

ETS proto-oncogene 2, transcription factor

affects expression

Vitamin K 3 affects the expression of ETS2 mRNA

NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319

G

exosome component 10

affects expression

Vitamin K 3 affects the expression of EXOSC10 mRNA

NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940

G

exosome component 8

affects expression

Vitamin K 3 affects the expression of EXOSC8 mRNA

NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

affects expression

Vitamin K 3 affects the expression of EZH2 mRNA

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

ezrin

affects expression

Vitamin K 3 affects the expression of EZR mRNA

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

coagulation factor X

multiple interactions

Vitamin K 3 inhibits the reaction [Ethyl Biscoumacetate results in decreased expression of F10 protein]

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

G

F2R like trypsin receptor 1

affects expression

Vitamin K 3 affects the expression of F2RL1 mRNA

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

G

coagulation factor VIII-associated 1

affects expression

Vitamin K 3 affects the expression of F8A1 mRNA

NCBI chr X:150,957,357...150,958,871
Ensembl chr X:150,916,679...150,960,168

G

fatty acid binding protein 1

affects expression

Vitamin K 3 affects the expression of FABP1 mRNA

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

Fas associated factor 1

affects expression

Vitamin K 3 affects the expression of FAF1 mRNA

NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977

G

family with sequence similarity 107, member B

affects expression

Vitamin K 3 affects the expression of FAM107B mRNA

NCBI chr17:74,478,608...74,685,027
Ensembl chr17:74,478,608...74,684,989

G

FAM111 trypsin like peptidase A

affects expression

Vitamin K 3 affects the expression of FAM111A mRNA

NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547

G

family with sequence similarity 174, member B

affects expression

Vitamin K 3 affects the expression of FAM174B mRNA

NCBI chr 1:127,515,393...127,618,591
Ensembl chr 1:127,514,041...127,596,128
Ensembl chr 1:127,514,041...127,596,128

G

FAM20C, golgi associated secretory pathway kinase

affects expression

Vitamin K 3 affects the expression of FAM20C mRNA

NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543

G

family with sequence similarity 217, member B

affects expression

Vitamin K 3 affects the expression of FAM217B mRNA

NCBI chr 3:165,505,574...165,515,273
Ensembl chr 3:165,501,532...165,513,377

G

family with sequence similarity 222, member B

affects expression

Vitamin K 3 affects the expression of FAM222B mRNA

NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350

G

family with sequence similarity 241 member B

affects expression

Vitamin K 3 affects the expression of FAM241B mRNA

NCBI chr20:30,052,315...30,055,247
Ensembl chr20:30,052,324...30,055,084

G

family with sequence similarity 89, member B

affects expression

Vitamin K 3 affects the expression of FAM89B mRNA

NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367

G

FA complementation group A

affects expression

Vitamin K 3 affects the expression of FANCA mRNA

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

FA complementation group F

affects expression

Vitamin K 3 affects the expression of FANCF mRNA

NCBI chr 1:101,449,120...101,451,936
Ensembl chr 1:101,450,389...101,451,923

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

affects expression

Vitamin K 3 affects the expression of FARP1 mRNA

NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299

G

phenylalanyl-tRNA synthetase subunit beta

affects expression

Vitamin K 3 affects the expression of FARSB mRNA

NCBI chr 9:79,887,852...79,947,082
Ensembl chr 9:79,887,842...79,947,045

G

Fas cell surface death receptor

increases expression

Vitamin K 3 results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

fatty acid hydroxylase domain containing 2

affects expression

Vitamin K 3 affects the expression of FAXDC2 mRNA

NCBI chr10:42,245,808...42,271,679
Ensembl chr10:42,246,868...42,271,871

G

fibulin 1

affects expression

Vitamin K 3 affects the expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

F-box and leucine-rich repeat protein 15

affects expression

Vitamin K 3 affects the expression of FBXL15 mRNA

NCBI chr 1:245,189,732...245,191,973
Ensembl chr 1:245,189,736...245,192,007

G

F-box and leucine-rich repeat protein 16

affects expression

Vitamin K 3 affects the expression of FBXL16 mRNA

NCBI chr10:14,829,453...14,841,739
Ensembl chr10:14,829,449...14,840,986

G

F-box protein 11

affects expression

Vitamin K 3 affects the expression of FBXO11 mRNA

NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662

G

F-box protein 21

affects expression

Vitamin K 3 affects the expression of FBXO21 mRNA

NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133

G

F-box protein 30

increases expression

Vitamin K 3 results in increased expression of FBXO30 mRNA

NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441

G

Fc gamma receptor 2B

affects expression

Vitamin K 3 affects the expression of FCGR2B mRNA

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

G

fucose kinase

affects expression

Vitamin K 3 affects the expression of FCSK mRNA

NCBI chr19:38,849,130...38,874,497
Ensembl chr19:38,854,762...38,874,418

G

ferredoxin reductase

affects expression
increases expression

Vitamin K 3 affects the expression of FDXR mRNA
Vitamin K 3 results in increased expression of FDXR mRNA

PMID:12414654 PMID:20044591

NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658

G

flap structure-specific endonuclease 1

decreases expression

Vitamin K 3 results in decreased expression of FEN1 mRNA

NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003

G

FERM domain containing kindlin 1

affects expression

Vitamin K 3 affects the expression of FERMT1 mRNA

NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555

G

fibroblast growth factor receptor 2

affects expression

Vitamin K 3 affects the expression of FGFR2 mRNA

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

fibrinogen gamma chain

increases expression
affects expression

Vitamin K 3 results in increased expression of FGG mRNA
Vitamin K 3 affects the expression of FGG mRNA

PMID:12414654 PMID:20044591

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

fragile histidine triad diadenosine triphosphatase

increases response to substance

FHIT protein results in increased susceptibility to Vitamin K 3

NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340

G

four and a half LIM domains 2

affects expression

Vitamin K 3 affects the expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

FGF1 intracellular binding protein

affects expression

Vitamin K 3 affects the expression of FIBP mRNA

NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399

G

factor interacting with PAPOLA and CPSF1

affects expression

Vitamin K 3 affects the expression of FIP1L1 mRNA

NCBI chr14:33,615,210...33,675,742
Ensembl chr14:33,617,720...33,675,708

G

FKBP prolyl isomerase 9

affects expression

Vitamin K 3 affects the expression of FKBP9 mRNA

NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721

G

folliculin

affects expression

Vitamin K 3 affects the expression of FLCN mRNA

NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769

G

filamin B

decreases expression

Vitamin K 3 results in decreased expression of FLNB mRNA

NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006

G

fibronectin leucine rich transmembrane protein 3

affects expression

Vitamin K 3 affects the expression of FLRT3 mRNA

NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841

G

FLVCR choline and heme transporter 1

affects expression

Vitamin K 3 affects the expression of FLVCR1 mRNA

NCBI chr13:102,586,263...102,608,647
Ensembl chr13:102,586,257...102,608,661

G

fragile X messenger ribonucleoprotein 1

affects expression

Vitamin K 3 affects the expression of FMR1 mRNA

NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050

G

fructosamine-3-kinase-related protein

affects expression

Vitamin K 3 affects the expression of FN3KRP mRNA

NCBI chr10:106,688,413...106,697,137
Ensembl chr10:106,688,439...106,697,134

G

fibronectin type III domain containing 3a

affects expression

Vitamin K 3 affects the expression of FNDC3A mRNA

NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784

G

focadhesin

affects expression

Vitamin K 3 affects the expression of FOCAD mRNA

NCBI chr 5:102,564,560...102,886,587
Ensembl chr 5:102,564,598...102,886,582

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

Vitamin K 3 analog results in increased expression of FOS mRNA; Vitamin K 3 results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box A1

affects expression

Vitamin K 3 affects the expression of FOXA1 mRNA

NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188

G

forkhead box A3

affects expression

Vitamin K 3 affects the expression of FOXA3 mRNA

NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box C1

affects expression

Vitamin K 3 affects the expression of FOXC1 mRNA

NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803

G

forkhead box D2

affects expression

Vitamin K 3 affects the expression of FOXD2 mRNA

NCBI chr 5:128,427,986...128,430,709
Ensembl chr 5:128,429,020...128,430,504

G

forkhead box J3

affects expression

Vitamin K 3 affects the expression of FOXJ3 mRNA

NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489

G

forkhead box M1

decreases expression

Vitamin K 3 results in decreased expression of FOXM1 mRNA

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box P1

affects expression

Vitamin K 3 affects the expression of FOXP1 mRNA

NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258

G

FERM domain containing 4A

affects expression

Vitamin K 3 affects the expression of FRMD4A mRNA

NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687

G

follicle stimulating hormone subunit beta

multiple interactions

Vitamin K 3 results in decreased expression of and results in decreased secretion of FSHB protein

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

ferritin light chain 1

affects expression
increases expression
multiple interactions

Vitamin K 3 affects the expression of FTL mRNA
Vitamin K 3 results in increased expression of FTL mRNA
Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]

PMID:12414654 PMID:12644586 PMID:20044591

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

ferritin mitochondrial

multiple interactions

Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]

NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123

G

fucose mutarotase

affects expression

Vitamin K 3 affects the expression of FUOM mRNA

NCBI chr 1:194,888,535...194,893,046
Ensembl chr 1:194,886,709...194,893,046

G

fucosyltransferase 1

affects expression

Vitamin K 3 affects the expression of FUT1 mRNA

NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616

G

fucosyltransferase 8

affects expression

Vitamin K 3 affects the expression of FUT8 mRNA

NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677

G

frizzled class receptor 4

affects expression

Vitamin K 3 affects the expression of FZD4 mRNA

NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724

G

frizzled class receptor 7

affects expression

Vitamin K 3 affects the expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

G0/G1switch 2

affects expression

Vitamin K 3 affects the expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

G2/M-phase specific E3 ubiquitin protein ligase

decreases expression

Vitamin K 3 results in decreased expression of G2E3 mRNA

NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924

G

alpha glucosidase

affects expression

Vitamin K 3 affects the expression of GAA mRNA

NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836

G

growth arrest and DNA-damage-inducible, beta

affects expression

Vitamin K 3 affects the expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

galanin and GMAP prepropeptide

affects expression

Vitamin K 3 affects the expression of GAL mRNA

NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959

G

galactose-3-O-sulfotransferase 1

affects expression

Vitamin K 3 affects the expression of GAL3ST1 mRNA

NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388

G

galactose mutarotase

affects expression

Vitamin K 3 affects the expression of GALM mRNA

NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310

G

polypeptide N-acetylgalactosaminyltransferase 11

affects expression

Vitamin K 3 affects the expression of GALNT11 mRNA

NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140

G

growth associated protein 43

increases expression

Vitamin K 3 analog results in increased expression of GAP43 mRNA

NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045

G

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

affects expression

Vitamin K 3 affects the expression of GART mRNA

NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125

G

GATA binding protein 6

affects expression

Vitamin K 3 affects the expression of GATA6 mRNA

NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532

G

glutamate-cysteine ligase, catalytic subunit

increases activity
increases expression
multiple interactions

Vitamin K 3 results in increased activity of GCLC protein
Vitamin K 3 results in increased expression of GCLC mRNA
Dactinomycin inhibits the reaction [Vitamin K 3 results in increased expression of GCLC mRNA]

PMID:11972604 PMID:23410634 PMID:25270620

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

Vitamin K 3 results in increased expression of GCLM mRNA

PMID:12414654 PMID:23410634 PMID:25270620

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glucosaminyl (N-acetyl) transferase 3, mucin type

increases expression

Vitamin K 3 results in increased expression of GCNT3 mRNA

NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562

G

growth differentiation factor 15

affects expression
increases expression

Vitamin K 3 affects the expression of GDF15 mRNA
Vitamin K 3 results in increased expression of GDF15 mRNA

PMID:12414654 PMID:20044591

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

GDP dissociation inhibitor 1

affects expression

Vitamin K 3 affects the expression of GDI1 mRNA

NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272

G

GDP dissociation inhibitor 2

affects expression

Vitamin K 3 affects the expression of GDI2 mRNA

NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366

G

glycerophosphodiester phosphodiesterase domain containing 5

affects expression

Vitamin K 3 affects the expression of GDPD5 mRNA

NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446

G

gem (nuclear organelle) associated protein 6

affects expression

Vitamin K 3 affects the expression of GEMIN6 mRNA

NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612

G

gamma-glutamyltransferase 1

decreases expression
multiple interactions

Vitamin K 3 results in decreased expression of GGT1 mRNA alternative form
Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of GGT1 protein]; Vitamin K 3 results in increased expression of and results in increased activity of GGT1 protein

NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442

G

growth hormone receptor

affects expression

Vitamin K 3 affects the expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

GRB10 interacting GYF protein 2

affects expression

Vitamin K 3 affects the expression of GIGYF2 mRNA

NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715

G

GIPC PDZ domain containing family, member 2

increases expression

Vitamin K 3 results in increased expression of GIPC2 mRNA

NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236

G

gap junction protein, alpha 1

affects expression

Vitamin K 3 affects the expression of GJA1 mRNA

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

glucocorticoid induced 1

affects expression

Vitamin K 3 affects the expression of GLCCI1 mRNA

NCBI chr 4:36,307,956...36,635,614
Ensembl chr 4:36,307,903...36,635,612

G

glycine decarboxylase

affects expression

Vitamin K 3 affects the expression of GLDC mRNA

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

golgi glycoprotein 1

affects expression

Vitamin K 3 affects the expression of GLG1 mRNA

NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178

G

glutaredoxin

increases expression

Vitamin K 3 results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutaminase

affects expression

Vitamin K 3 affects the expression of GLS mRNA

NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900

G

glycosyltransferase 8 domain containing 1

affects expression

Vitamin K 3 affects the expression of GLT8D1 mRNA

NCBI chr16:6,192,269...6,207,227
Ensembl chr16:6,192,300...6,207,229

G

glycerate kinase

affects expression

Vitamin K 3 affects the expression of GLYCTK mRNA

NCBI chr 8:106,795,461...106,802,675
Ensembl chr 8:106,797,343...106,802,397

G

G protein subunit alpha i1

affects expression

Vitamin K 3 affects the expression of GNAI1 mRNA

NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417

G

G protein subunit alpha z

affects expression

Vitamin K 3 affects the expression of GNAZ mRNA

NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907

G

glyceronephosphate O-acyltransferase

affects expression

Vitamin K 3 affects the expression of GNPAT mRNA

NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361

G

golgin A3

affects expression

Vitamin K 3 affects the expression of GOLGA3 mRNA

NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509

G

gon-4 like

affects expression

Vitamin K 3 affects the expression of GON4L mRNA

NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634

G

golgi associated PDZ and coiled-coil motif containing

affects expression

Vitamin K 3 affects the expression of GOPC mRNA

NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903

G

G patch domain and ankyrin repeats 1

affects expression

Vitamin K 3 affects the expression of GPANK1 mRNA

NCBI chr20:3,697,641...3,700,814
Ensembl chr20:3,697,641...3,700,858

G

glycerol-3-phosphate acyltransferase 3

increases expression

Vitamin K 3 results in increased expression of GPAT3 mRNA

NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490

G

GC-rich promoter binding protein 1

affects expression

Vitamin K 3 affects the expression of GPBP1 mRNA

NCBI chr 2:43,023,504...43,091,146
Ensembl chr 2:43,023,504...43,090,907

G

G protein-coupled receptor 160

affects expression

Vitamin K 3 affects the expression of GPR160 mRNA

NCBI chr 2:112,483,364...112,563,072
Ensembl chr 2:112,484,935...112,563,148

G

G protein-coupled receptor, class C, group 5, member A

affects expression

Vitamin K 3 affects the expression of GPRC5A mRNA

NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260

G

G protein-coupled receptor, class C, group 5, member B

affects expression

Vitamin K 3 affects the expression of GPRC5B mRNA

NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932

G

G protein-coupled receptor, class C, group 5, member C

affects expression

Vitamin K 3 affects the expression of GPRC5C mRNA

NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926

G

glutamic--pyruvic transaminase 2

affects expression

Vitamin K 3 affects the expression of GPT2 mRNA

NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610

G

glutathione peroxidase 1

decreases response to substance

GPX1 protein results in decreased susceptibility to Vitamin K 3

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

increases expression

Vitamin K 3 results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutamate ionotropic receptor delta type subunit 1

affects expression

Vitamin K 3 affects the expression of GRID1 mRNA

NCBI chr16:10,138,564...10,885,803
Ensembl chr16:10,138,925...10,885,808

G

glutamate ionotropic receptor NMDA type subunit 2C

increases expression

Vitamin K 3 results in increased expression of GRIN2C mRNA

NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427

G

G protein-coupled receptor kinase 5

affects expression

Vitamin K 3 affects the expression of GRK5 mRNA

NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701

G

granulin precursor

affects expression

Vitamin K 3 affects the expression of GRN mRNA

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

G

glutamate-rich WD repeat containing 1

affects expression

Vitamin K 3 affects the expression of GRWD1 mRNA

NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201

G

gasdermin E

affects expression

Vitamin K 3 affects the expression of GSDME mRNA

NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806

G

glycogen synthase kinase 3 beta

increases expression

Vitamin K 3 results in increased expression of GSK3B protein

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

gelsolin

affects response to substance

GSN mRNA affects the susceptibility to Vitamin K 3

PMID:14652020 PMID:15033777

NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402

G

glutathione-disulfide reductase

increases expression

Vitamin K 3 results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 1

affects expression

Vitamin K 3 affects the expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

affects expression

Vitamin K 3 affects the expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 4

affects expression

Vitamin K 3 affects the expression of GSTA4 mRNA

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase alpha 5

affects expression

Vitamin K 3 affects the expression of GSTA5 mRNA

PMID:20044591 PMID:20829426

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

increases expression

Vitamin K 3 results in increased expression of GSTM1 mRNA

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase omega 1

affects expression

Vitamin K 3 affects the expression of GSTO1 mRNA

NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468

G

general transcription factor II I

affects expression

Vitamin K 3 affects the expression of GTF2I mRNA

NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243

G

general transcription factor IIIC subunit 2

affects expression

Vitamin K 3 affects the expression of GTF3C2 mRNA

NCBI chr 6:25,196,439...25,221,338
Ensembl chr 6:25,197,268...25,220,490

G

GTP binding protein 3

affects expression

Vitamin K 3 affects the expression of GTPBP3 mRNA

NCBI chr16:18,175,766...18,180,857
Ensembl chr16:18,175,766...18,180,857

G

GTP binding protein 4

affects expression

Vitamin K 3 affects the expression of GTPBP4 mRNA

NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009

G

guanylate cyclase 1 soluble subunit alpha 1

decreases expression

Vitamin K 3 results in decreased expression of GUCY1A1 protein

NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671

G

guanylate cyclase 1 soluble subunit beta 1

decreases expression

Vitamin K 3 results in decreased expression of GUCY1B1 protein

NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916

G

guanylate cyclase 2C

affects expression

Vitamin K 3 affects the expression of GUCY2C mRNA

NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092

G

glucuronidase, beta

affects expression

Vitamin K 3 affects the expression of GUSB mRNA

NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905

G

H1.4 linker histone, cluster member

affects expression

Vitamin K 3 affects the expression of H1-4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

H1.5 linker histone, cluster member

affects expression

Vitamin K 3 affects the expression of H1-5 mRNA

NCBI chr17:42,726,132...42,727,162
Ensembl chr17:42,726,127...42,769,160

G

H2A clustered histone 18

affects expression

Vitamin K 3 affects the expression of H2AC18 mRNA

NCBI chr 2:183,808,398...183,808,992

G

H2A clustered histone 20

affects expression

Vitamin K 3 affects the expression of H2AC20 mRNA

NCBI chr 2:183,779,879...183,780,357

G

H2A clustered histone 25

affects expression

Vitamin K 3 affects the expression of H2AC25 mRNA

NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874

G

H2A.J histone

affects expression

Vitamin K 3 affects the expression of H2AJ mRNA

NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006

G

H2A.X variant histone

multiple interactions

[Ascorbic Acid results in increased reduction of Vitamin K 3] which results in increased phosphorylation of H2AX protein

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

H2B clustered histone 3

affects expression

Vitamin K 3 affects the expression of H2BC3 mRNA

NCBI chr17:41,380,056...41,380,686

G

H2B clustered histone 6

affects expression

Vitamin K 3 affects the expression of H2BC6 mRNA

NCBI chr17:41,520,775...41,521,238

G

H2B clustered histone 9

affects expression

Vitamin K 3 affects the expression of H2BC9 mRNA

NCBI chr17:42,470,593...42,478,590

G

H2B.U histone 1

affects expression

Vitamin K 3 affects the expression of H2BC26 mRNA

NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277

G

hydroxyacyl-CoA dehydrogenase

affects expression

Vitamin K 3 affects the expression of HADH mRNA

NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353

G

hepcidin antimicrobial peptide

affects expression

Vitamin K 3 affects the expression of HAMP mRNA

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

histidyl-tRNA synthetase 2, mitochondrial

affects expression

Vitamin K 3 affects the expression of HARS2 mRNA

NCBI chr18:28,398,790...28,408,075
Ensembl chr18:28,398,795...28,414,747

G

hepatitis A virus cellular receptor 1

affects expression

Vitamin K 3 affects the expression of HAVCR1 mRNA

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

hemoglobin alpha, adult chain 3

affects expression

Vitamin K 3 affects the expression of HBA2 mRNA

NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481

G

HMG-box transcription factor 1

affects expression

Vitamin K 3 affects the expression of HBP1 mRNA

NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787

G

hydroxycarboxylic acid receptor 1

affects expression

Vitamin K 3 affects the expression of HCAR1 mRNA

NCBI chr12:32,710,680...32,713,934
Ensembl chr12:32,711,027...32,712,082

G

holocytochrome c synthase

affects expression

Vitamin K 3 affects the expression of HCCS mRNA

NCBI chr X:24,932,943...24,942,376
Ensembl chr X:24,933,002...24,942,366

G

host cell factor C1 regulator 1

affects expression

Vitamin K 3 affects the expression of HCFC1R1 mRNA

NCBI chr10:12,705,139...12,706,852
Ensembl chr10:12,705,077...12,706,850

G

histone deacetylase 11

affects expression

Vitamin K 3 affects the expression of HDAC11 mRNA

NCBI chr 4:123,645,873...123,667,407
Ensembl chr 4:123,650,157...123,667,405

G

histone deacetylase 2

affects expression

Vitamin K 3 affects the expression of HDAC2 mRNA

NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609

G

HEAT repeat containing 1

affects expression

Vitamin K 3 affects the expression of HEATR1 mRNA

NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948

G

hdc homolog, cell cycle regulator

affects expression

Vitamin K 3 affects the expression of HECA mRNA

NCBI chr 1:12,525,445...12,575,358
Ensembl chr 1:12,525,135...12,576,427

G

hephaestin

affects expression

Vitamin K 3 affects the expression of HEPH mRNA

NCBI chr X:61,151,131...61,402,980
Ensembl chr X:61,296,345...61,402,980

G

HECT and RLD domain containing E3 ubiquitin protein ligase 2

affects expression

Vitamin K 3 affects the expression of HERC2 mRNA

NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134

G

homocysteine inducible ER protein with ubiquitin like domain 1

affects expression

Vitamin K 3 affects the expression of HERPUD1 mRNA

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hes family bHLH transcription factor 1

affects expression
increases expression
multiple interactions

Vitamin K 3 affects the expression of HES1 mRNA
Vitamin K 3 results in increased expression of HES1 protein
EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of HES1 protein]

PMID:20044591 PMID:25005833

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hes family bHLH transcription factor 6

affects expression

Vitamin K 3 affects the expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

heparan-alpha-glucosaminide N-acetyltransferase

affects expression

Vitamin K 3 affects the expression of HGSNAT mRNA

NCBI chr16:66,105,233...66,137,444
Ensembl chr16:66,105,181...66,136,138

G

3-hydroxyisobutyrate dehydrogenase

affects expression

Vitamin K 3 affects the expression of HIBADH mRNA

NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617

G

hypoxia inducible factor 1 subunit alpha

increases expression
multiple interactions

Vitamin K 3 results in increased expression of HIF1A mRNA; Vitamin K 3 results in increased expression of HIF1A protein
Vitamin K 3 inhibits the reaction [carbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein]; Vitamin K 3 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Vitamin K 3 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]

PMID:12595275 PMID:16507596

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hypoxia inducible factor 3 subunit alpha

affects expression

Vitamin K 3 affects the expression of HIF3A mRNA

NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758

G

homeodomain interacting protein kinase 2

affects expression

Vitamin K 3 affects the expression of HIPK2 mRNA

NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223

G

histone cluster 1 H2A family member F

affects expression

Vitamin K 3 affects the expression of H2AC8 mRNA

NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796

G

histone cluster 1 H2B family member Q

affects expression

Vitamin K 3 affects the expression of H2BC7 mRNA

NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153

G

histone cluster 1, H4m

affects expression

Vitamin K 3 affects the expression of H4C1 mRNA

NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958

G

holocarboxylase synthetase

affects expression

Vitamin K 3 affects the expression of HLCS mRNA

NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222

G

homeobox containing 1

affects expression

Vitamin K 3 affects the expression of HMBOX1 mRNA

NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323

G

high mobility group box 3

affects expression

Vitamin K 3 affects the expression of HMGB3 mRNA

NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression
multiple interactions
decreases activity

Vitamin K 3 results in increased expression of HMGCR mRNA
manganese protoporphyrin inhibits the reaction [Vitamin K 3 results in decreased activity of HMGCR protein]; tempol inhibits the reaction [Vitamin K 3 results in decreased activity of HMGCR protein]

PMID:12414654 PMID:21257924

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

affects expression

Vitamin K 3 affects the expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heme oxygenase 1

increases expression

Vitamin K 3 results in increased expression of HMOX1 mRNA

PMID:12414654 PMID:19386027 PMID:23410634

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

histamine N-methyltransferase

affects expression

Vitamin K 3 affects the expression of HNMT mRNA

NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012

G

homeo box D1

affects expression

Vitamin K 3 affects the expression of HOXD1 mRNA

NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769

G

haptoglobin

affects expression

Vitamin K 3 affects the expression of HP mRNA

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

heat shock factor binding protein 1

affects expression

Vitamin K 3 affects the expression of HSBP1 mRNA

NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821

G

hydroxysteroid 11-beta dehydrogenase 2

affects expression

Vitamin K 3 affects the expression of HSD11B2 mRNA

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

G

hydroxysteroid (17-beta) dehydrogenase 11

affects expression

Vitamin K 3 affects the expression of HSD17B11 mRNA

NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161

G

hydroxysteroid (17-beta) dehydrogenase 4

affects expression

Vitamin K 3 affects the expression of HSD17B4 mRNA

NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

affects expression
multiple interactions

Vitamin K 3 affects the expression of HSD3B1 mRNA
[Vitamin K 3 co-treated with NADP] binds to HSD3B1 protein

PMID:20044591 PMID:25526675

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

heat shock transcription factor 1

increases activity

Vitamin K 3 results in increased activity of HSF1 protein

NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011

G

heat shock protein 90 beta family member 1

affects expression

Vitamin K 3 affects the expression of HSP90B1 mRNA

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 1A

affects expression
increases expression

Vitamin K 3 affects the expression of HSPA1A mRNA
Vitamin K 3 results in increased expression of HSPA1A mRNA

PMID:12414654 PMID:20044591

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

Vitamin K 3 results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 5

multiple interactions
increases expression

Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of HSPA5 protein]; S 3483 promotes the reaction [Vitamin K 3 results in increased expression of HSPA5 protein]

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

Vitamin K 3 results in increased expression of HSPA6 mRNA

NCBI chr13:83,273,176...83,274,317

G

heat shock protein family B (small) member 1

affects expression

Vitamin K 3 affects the expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

HIV-1 Tat interactive protein 2

increases expression

Vitamin K 3 results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

isoleucyl-tRNA synthetase 1

affects expression

Vitamin K 3 affects the expression of IARS1 mRNA

NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237

G

islet cell autoantigen 1

affects expression

Vitamin K 3 affects the expression of ICA1 mRNA

NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298

G

inducible T-cell co-stimulator ligand

decreases expression

Vitamin K 3 results in decreased expression of ICOSL mRNA

NCBI chr20:10,600,420...10,610,718
Ensembl chr20:10,600,420...10,610,703

G

inhibitor of DNA binding 1

affects expression

Vitamin K 3 affects the expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

immediate early response 5

affects expression

Vitamin K 3 affects the expression of IER5 mRNA

NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227

G

IFI30, lysosomal thiol reductase

affects expression

Vitamin K 3 affects the expression of IFI30 mRNA

NCBI chr16:18,675,590...18,679,655
Ensembl chr16:18,675,613...18,681,175

G

interferon-induced protein with tetratricopeptide repeats 3

affects expression

Vitamin K 3 affects the expression of IFIT3 mRNA

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

intraflagellar transport 22

affects expression

Vitamin K 3 affects the expression of IFT22 mRNA

NCBI chr12:19,759,072...19,768,859
Ensembl chr12:19,761,790...19,768,809

G

insulin-like growth factor 1 receptor

affects expression

Vitamin K 3 affects the expression of IGF1R mRNA

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2 receptor

affects expression

Vitamin K 3 affects the expression of IGF2R mRNA

NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501

G

insulin-like growth factor binding protein 2

decreases expression

Vitamin K 3 results in decreased expression of IGFBP2 mRNA

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 5

increases expression

Vitamin K 3 results in increased expression of IGFBP5 mRNA

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

interleukin 11

affects expression

Vitamin K 3 affects the expression of IL11 mRNA

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 1 alpha

multiple interactions
increases secretion
increases expression

Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1A mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1A protein]
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3

PMID:19265712 PMID:19362101

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

multiple interactions
increases expression
increases secretion

Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1B mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1B protein]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin enhancer binding factor 2

affects expression

Vitamin K 3 affects the expression of ILF2 mRNA

NCBI chr 2:175,952,174...175,971,191
Ensembl chr 2:175,952,186...175,971,337

G

inhibin subunit beta B

affects expression
increases expression

Vitamin K 3 affects the expression of INHBB mRNA
Vitamin K 3 results in increased expression of INHBB mRNA

PMID:12414654 PMID:20044591

NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832

G

insulin induced gene 2

affects expression

Vitamin K 3 affects the expression of INSIG2 mRNA

NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923

G

integrator complex subunit 10

affects expression

Vitamin K 3 affects the expression of INTS10 mRNA

NCBI chr16:20,915,223...20,947,146
Ensembl chr16:20,916,082...20,967,610

G

importin 7

affects expression

Vitamin K 3 affects the expression of IPO7 mRNA

NCBI chr 1:164,062,702...164,102,938
Ensembl chr 1:164,062,702...164,102,938

G

interferon regulatory factor 2 binding protein 2

affects expression

Vitamin K 3 affects the expression of IRF2BP2 mRNA

NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642

G

interferon regulatory factor 5

affects expression

Vitamin K 3 affects the expression of IRF5 mRNA

NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267

G

iroquois homeobox 5

affects expression

Vitamin K 3 affects the expression of IRX5 mRNA

NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318

G

interferon stimulated exonuclease gene 20

affects expression

Vitamin K 3 affects the expression of ISG20 mRNA

NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027

G

interferon stimulated exonuclease gene 20-like 2

affects expression

Vitamin K 3 affects the expression of ISG20L2 mRNA

NCBI chr 2:173,396,780...173,407,102
Ensembl chr 2:173,396,780...173,406,614

G

integrin subunit alpha 4

affects expression

Vitamin K 3 affects the expression of ITGA4 mRNA

NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715

G

inositol 1,4,5-trisphosphate receptor, type 3

affects expression

Vitamin K 3 affects the expression of ITPR3 mRNA

PMID:20044591 PMID:23410634

NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337

G

ITPR interacting domain containing 2

affects expression

Vitamin K 3 affects the expression of ITPRID2 mRNA

NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978

G

jagged canonical Notch ligand 1

affects expression

Vitamin K 3 affects the expression of JAG1 mRNA

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

Janus kinase 1

affects expression

Vitamin K 3 affects the expression of JAK1 mRNA

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

G

Janus kinase 3

multiple interactions
increases phosphorylation

[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]; [[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]; [Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein; JAK3 protein promotes the reaction [Vitamin K 3 results in increased phosphorylation of ELAVL1 protein]

NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536

G

junction adhesion molecule like

affects expression

Vitamin K 3 affects the expression of JAML mRNA

NCBI chr 8:45,384,836...45,415,459
Ensembl chr 8:45,383,495...45,416,565

G

jumonji and AT-rich interaction domain containing 2

affects expression

Vitamin K 3 affects the expression of JARID2 mRNA

NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

Vitamin K 3 results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

KN motif and ankyrin repeat domains 1

affects expression

Vitamin K 3 affects the expression of KANK1 mRNA

NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514

G

lysine acetyltransferase 2A

affects expression

Vitamin K 3 affects the expression of KAT2A mRNA

NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166

G

Kazal-type serine peptidase inhibitor domain 1

affects expression

Vitamin K 3 affects the expression of KAZALD1 mRNA

NCBI chr 1:243,939,596...243,943,060
Ensembl chr 1:243,939,647...243,943,059

G

kelch repeat and BTB domain containing 11

affects expression

Vitamin K 3 affects the expression of KBTBD11 mRNA

NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736

G

potassium inwardly-rectifying channel, subfamily J, member 14

affects expression

Vitamin K 3 affects the expression of KCNJ14 mRNA

NCBI chr 1:96,293,159...96,300,810
Ensembl chr 1:96,293,435...96,495,459

G

potassium inwardly-rectifying channel, subfamily J, member 16

affects expression

Vitamin K 3 affects the expression of KCNJ16 mRNA

NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702

G

potassium calcium-activated channel subfamily N member 4

affects expression

Vitamin K 3 affects the expression of KCNN4 mRNA

NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340

G

potassium channel tetramerization domain containing 10

affects expression

Vitamin K 3 affects the expression of KCTD10 mRNA

NCBI chr12:42,230,159...42,248,792
Ensembl chr12:42,230,269...42,248,783

G

potassium channel tetramerization domain containing 21

affects expression

Vitamin K 3 affects the expression of KCTD21 mRNA

NCBI chr 1:151,650,074...151,669,775
Ensembl chr 1:151,650,104...151,667,645

G

lysine demethylase 2B

affects expression

Vitamin K 3 affects the expression of KDM2B mRNA

NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355

G

lysine demethylase 3A

affects expression

Vitamin K 3 affects the expression of KDM3A mRNA

NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073

G

lysine demethylase 3B

affects expression

Vitamin K 3 affects the expression of KDM3B mRNA

NCBI chr18:26,380,859...26,436,701
Ensembl chr18:26,380,964...26,436,628

G

Kelch-like ECH-associated protein 1

multiple interactions
decreases expression

[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Vitamin K 3
Vitamin K 3 results in decreased expression of KEAP1 mRNA

PMID:19608619 PMID:23410634

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

KH RNA binding domain containing, signal transduction associated 1

affects expression

Vitamin K 3 affects the expression of KHDRBS1 mRNA

NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180

G

KIAA1549 homolog

affects expression

Vitamin K 3 affects the expression of KIAA1549 mRNA

NCBI chr 4:66,840,674...66,968,407
Ensembl chr 4:66,760,162...66,968,436

G

kinesin family member 13B

affects expression

Vitamin K 3 affects the expression of KIF13B mRNA

NCBI chr15:38,908,257...39,066,021
Ensembl chr15:38,924,624...39,084,879

G

kinesin family member 15

affects expression

Vitamin K 3 affects the expression of KIF15 mRNA

NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750

G

kinesin family member 1B

affects expression

Vitamin K 3 affects the expression of KIF1B mRNA

NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778

G

kinesin family member 23

affects expression

Vitamin K 3 affects the expression of KIF23 mRNA

PMID:20044591 PMID:23410634

NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072

G

kinesin family member 2C

affects expression

Vitamin K 3 affects the expression of KIF2C mRNA

NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637

G

KISS1 receptor

affects expression

Vitamin K 3 affects the expression of KISS1R mRNA

NCBI chr 7:9,785,135...9,790,283
Ensembl chr 7:9,785,135...9,788,793

G

KLF transcription factor 10

affects expression

Vitamin K 3 affects the expression of KLF10 mRNA

PMID:20044591 PMID:23410634

NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994

G

KLF transcription factor 11

affects expression

Vitamin K 3 affects the expression of KLF11 mRNA

NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550

G

KLF transcription factor 6

affects expression
increases expression
multiple interactions

Vitamin K 3 affects the expression of KLF6 mRNA
Vitamin K 3 results in increased expression of KLF6 mRNA; Vitamin K 3 results in increased expression of KLF6 mRNA alternative form; Vitamin K 3 results in increased expression of KLF6 protein
[Arachidonic Acid co-treated with Vitamin K 3] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein; Buthionine Sulfoximine promotes the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Dicumarol inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; S-ethyl glutathione inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Vitamin K 3 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]

PMID:20044591 PMID:22486562

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

kininogen 1

affects expression

Vitamin K 3 affects the expression of KNG1 mRNA

NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555

G

karyopherin subunit beta 1

affects expression

Vitamin K 3 affects the expression of KPNB1 mRNA

NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605

G

KRI1 homolog

affects expression

Vitamin K 3 affects the expression of KRI1 mRNA

NCBI chr 8:19,817,005...19,831,516
Ensembl chr 8:19,817,017...19,831,392

G

keratin 10

affects expression

Vitamin K 3 affects the expression of KRT10 mRNA

NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701

G

keratin 23

affects expression

Vitamin K 3 affects the expression of KRT23 mRNA

NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983

G

keratin 8

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

kynureninase

affects expression

Vitamin K 3 affects the expression of KYNU mRNA

NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488

G

laminin subunit alpha 5

affects expression

Vitamin K 3 affects the expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

laminin subunit beta 2

affects expression

Vitamin K 3 affects the expression of LAMB2 mRNA

NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549

G

laminin subunit gamma 1

affects expression

Vitamin K 3 affects the expression of LAMC1 mRNA

NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

affects expression

Vitamin K 3 affects the expression of LAMTOR2 mRNA

NCBI chr 2:174,008,556...174,011,950
Ensembl chr 2:174,008,548...174,013,013

G

LARGE xylosyl- and glucuronyltransferase 1

affects expression

Vitamin K 3 affects the expression of LARGE1 mRNA

NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930

G

La ribonucleoprotein 1B

affects expression

Vitamin K 3 affects the expression of LARP1B mRNA

NCBI chr 2:123,936,057...123,969,254
Ensembl chr 2:123,935,983...123,968,896

G

La ribonucleoprotein 6, translational regulator

affects expression

Vitamin K 3 affects the expression of LARP6 mRNA

NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535

G

LAS1-like, ribosome biogenesis factor

affects expression

Vitamin K 3 affects the expression of LAS1L mRNA

NCBI chr X:60,851,969...60,873,717
Ensembl chr X:60,851,962...60,873,687

G

large tumor suppressor kinase 2

affects expression

Vitamin K 3 affects the expression of LATS2 mRNA

NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220

G

lipopolysaccharide binding protein

affects expression

Vitamin K 3 affects the expression of LBP mRNA

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

G

lamin B receptor

decreases expression

Vitamin K 3 results in decreased expression of LBR mRNA

NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017

G

lactate dehydrogenase A

affects expression

Vitamin K 3 affects the expression of LDHA mRNA

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

lactate dehydrogenase D

affects expression

Vitamin K 3 affects the expression of LDHD mRNA

NCBI chr19:39,583,529...39,588,397
Ensembl chr19:39,573,621...39,595,575

G

low density lipoprotein receptor

increases expression

Vitamin K 3 results in increased expression of LDLR mRNA

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

lymphoid enhancer binding factor 1

decreases expression

Vitamin K 3 results in decreased expression of LEF1 mRNA

NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794

G

LEO1 homolog, Paf1/RNA polymerase II complex component

affects expression

Vitamin K 3 affects the expression of LEO1 mRNA

NCBI chr 8:76,199,547...76,223,983
Ensembl chr 8:76,199,099...76,223,983

G

leptin

multiple interactions
increases expression

1,2-linoleoylphosphatidylcholine inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]; S-Adenosylmethionine inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]; SB 203580 inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

leptin receptor overlapping transcript

affects expression

Vitamin K 3 affects the expression of LEPROT mRNA

NCBI chr 5:116,289,843...116,301,951
Ensembl chr 5:116,289,822...116,301,988

G

galectin 8

affects expression

Vitamin K 3 affects the expression of LGALS8 mRNA

NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764

G

leucine rich repeat containing G protein coupled receptor 5

affects expression

Vitamin K 3 affects the expression of LGR5 mRNA

NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446

G

lengsin, lens protein with glutamine synthetase domain

affects expression

Vitamin K 3 affects the expression of LGSN mRNA

NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907

G

luteinizing hormone subunit beta

multiple interactions

Vitamin K 3 results in decreased expression of and results in decreased secretion of LHB protein

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

LIM homeobox 6

affects expression

Vitamin K 3 affects the expression of LHX6 mRNA

NCBI chr 3:19,432,439...19,456,268
Ensembl chr 3:19,433,494...19,456,061

G

LIF, interleukin 6 family cytokine

increases expression

Vitamin K 3 results in increased expression of LIF mRNA

PMID:12414654 PMID:23410634

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

G

limb development membrane protein 1

affects expression

Vitamin K 3 affects the expression of LMBR1 mRNA

NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368

G

LIM and cysteine-rich domains 1

affects expression

Vitamin K 3 affects the expression of LMCD1 mRNA

NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046

G

lamin B1

affects expression

Vitamin K 3 affects the expression of LMNB1 mRNA

NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502

G

lon peptidase 1, mitochondrial

affects expression

Vitamin K 3 affects the expression of LONP1 mRNA

NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771

G

lysyl oxidase

affects expression

Vitamin K 3 affects the expression of LOX mRNA

NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477

G

leucine rich repeat and fibronectin type III domain containing 3

affects expression

Vitamin K 3 affects the expression of LRFN3 mRNA

NCBI chr 1:85,616,862...85,623,725
Ensembl chr 1:85,616,868...85,623,725

G

leucine-rich repeats and immunoglobulin-like domains 1

affects expression

Vitamin K 3 affects the expression of LRIG1 mRNA

NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513

G

LDL receptor related protein 1

affects expression

Vitamin K 3 affects the expression of LRP1 mRNA

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

G

LDL receptor related protein 6

increases expression

Vitamin K 3 results in increased expression of LRP6 mRNA

NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497

G

leucine rich repeat containing 8 VRAC subunit E

affects expression

Vitamin K 3 affects the expression of LRRC8E mRNA

NCBI chr12:2,578,240...2,589,407
Ensembl chr12:2,578,315...2,589,412

G

leucine-rich repeats and WD repeat domain containing 1

affects expression

Vitamin K 3 affects the expression of LRWD1 mRNA

NCBI chr12:20,530,035...20,543,078
Ensembl chr12:20,530,012...20,549,536

G

LSM14A mRNA processing body assembly factor

affects expression

Vitamin K 3 affects the expression of LSM14A mRNA

NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276

G

leukotriene A4 hydrolase

affects expression

Vitamin K 3 affects the expression of LTA4H mRNA

NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600

G

LTV1 ribosome biogenesis factor

affects expression

Vitamin K 3 affects the expression of LTV1 mRNA

NCBI chr 1:7,565,673...7,578,398
Ensembl chr 1:7,565,669...7,578,563

G

Ly1 antibody reactive

affects expression

Vitamin K 3 affects the expression of LYAR mRNA

NCBI chr14:72,576,878...72,590,854
Ensembl chr14:72,576,879...72,590,612

G

mab-21 like 4

affects expression

Vitamin K 3 affects the expression of MAB21L4 mRNA

NCBI chr 9:93,690,455...93,701,267
Ensembl chr 9:93,690,999...93,700,506

G

MAF bZIP transcription factor

affects expression

Vitamin K 3 affects the expression of MAF mRNA

NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365

G

MAF bZIP transcription factor F

affects expression

Vitamin K 3 affects the expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

MAF bZIP transcription factor G

increases expression
affects expression

Vitamin K 3 results in increased expression of MAFG mRNA
Vitamin K 3 affects the expression of MAFG mRNA

PMID:12414654 PMID:20044591

NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026

G

MAGE family member D1

affects expression

Vitamin K 3 affects the expression of MAGED1 mRNA

NCBI chr X:59,422,715...59,429,381
Ensembl chr X:59,422,717...59,429,364

G

monoamine oxidase B

multiple interactions
decreases activity

Vitamin K 3 inhibits the reaction [MAOB protein results in increased oxidation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine]
Vitamin K 3 results in decreased activity of MAOB protein

NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions

[Metyrapone co-treated with Vitamin K 3] results in increased expression of MAP1LC3B protein; [S 3483 co-treated with Vitamin K 3] results in increased expression of MAP1LC3B protein

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

microtubule-associated protein 4

affects expression

Vitamin K 3 affects the expression of MAP4 mRNA

NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362

G

mitogen-activated protein kinase kinase kinase kinase 4

affects expression

Vitamin K 3 affects the expression of MAP4K4 mRNA

NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation
increases activity

Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK1 protein]
schizandrin B promotes the reaction [Vitamin K 3 results in increased activity of MAPK1 protein]
[1,2-linoleoylphosphatidylcholine co-treated with S-Adenosylmethionine] inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK1 protein]

PMID:11880281 PMID:16310883 PMID:16507596 PMID:16996477 PMID:21250784

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 10

decreases activity
multiple interactions

Vitamin K 3 results in decreased activity of MAPK10 protein
Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK10 protein

PMID:10531305 PMID:19386027

NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation
increases activity

Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK3 protein]
schizandrin B promotes the reaction [Vitamin K 3 results in increased activity of MAPK3 protein]
[1,2-linoleoylphosphatidylcholine co-treated with S-Adenosylmethionine] inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK3 protein]

PMID:11880281 PMID:16310883 PMID:16507596 PMID:16996477 PMID:21250784

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions
increases activity
affects response to substance
increases phosphorylation

Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK8 protein
Vitamin K 3 results in increased activity of MAPK8 protein
MAPK8 protein affects the susceptibility to Vitamin K 3
Vitamin K 3 results in increased phosphorylation of MAPK8 protein

PMID:12215205 PMID:16310883 PMID:19386027

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

methionine adenosyltransferase 2A

affects expression

Vitamin K 3 affects the expression of MAT2A mRNA

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

G

methyl-CpG binding domain protein 2

affects expression

Vitamin K 3 affects the expression of MBD2 mRNA

NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794

G

melanocortin 1 receptor

affects expression

Vitamin K 3 affects the expression of MC1R mRNA

NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192

G

methylcrotonyl-CoA carboxylase subunit 1

affects expression

Vitamin K 3 affects the expression of MCCC1 mRNA

NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222

G

MCF.2 cell line derived transforming sequence-like

affects expression

Vitamin K 3 affects the expression of MCF2L mRNA

NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733

G

minichromosome maintenance complex component 3

affects expression

Vitamin K 3 affects the expression of MCM3 mRNA

PMID:20044591 PMID:23410634

NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314

G

minichromosome maintenance complex component 5

affects expression

Vitamin K 3 affects the expression of MCM5 mRNA

PMID:20044591 PMID:23410634

NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389

G

minichromosome maintenance complex component 6

affects expression

Vitamin K 3 affects the expression of MCM6 mRNA

NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960

G

minichromosome maintenance complex binding protein

affects expression

Vitamin K 3 affects the expression of MCMBP mRNA

NCBI chr 1:183,270,598...183,316,975
Ensembl chr 1:183,271,980...183,316,975

G

mediator of DNA damage checkpoint 1

affects expression

Vitamin K 3 affects the expression of MDC1 mRNA

NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240

G

MDM2 proto-oncogene

multiple interactions
decreases expression

EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of MDM2 protein]

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

malic enzyme 1

increases expression

Vitamin K 3 results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

mediator complex subunit 9

affects expression

Vitamin K 3 affects the expression of MED9 mRNA

NCBI chr10:44,750,667...44,765,464
Ensembl chr10:44,750,698...44,765,464

G

MET proto-oncogene, receptor tyrosine kinase

increases expression

Vitamin K 3 results in increased expression of MET mRNA

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

G

methionyl aminopeptidase 1

affects expression

Vitamin K 3 affects the expression of METAP1 mRNA

NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434

G

mex-3 RNA binding family member D

affects expression

Vitamin K 3 affects the expression of MEX3D mRNA

NCBI chr 7:9,325,575...9,332,705
Ensembl chr 7:9,325,488...9,332,096

G

mitochondrial fission factor

affects expression

Vitamin K 3 affects the expression of MFF mRNA

NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039

G

milk fat globule EGF and factor V/VIII domain containing

affects expression

Vitamin K 3 affects the expression of MFGE8 mRNA

NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073

G

major facilitator superfamily domain containing 1

affects expression

Vitamin K 3 affects the expression of MFSD1 mRNA

NCBI chr 2:151,846,130...151,866,168
Ensembl chr 2:151,846,146...151,867,045

G

major facilitator superfamily domain containing 5

affects expression

Vitamin K 3 affects the expression of MFSD5 mRNA

NCBI chr 7:133,409,096...133,411,377
Ensembl chr 7:133,402,537...133,411,396

G

MIA SH3 domain ER export factor 2

increases expression

Vitamin K 3 results in increased expression of MIA2 mRNA

NCBI chr 6:76,787,508...76,885,246
Ensembl chr 6:76,787,508...76,885,211

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

affects expression

Vitamin K 3 affects the expression of MICAL2 mRNA

NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719

G

MINDY lysine 48 deubiquitinase 1

affects expression

Vitamin K 3 affects the expression of MINDY1 mRNA

NCBI chr 2:182,859,977...182,873,000
Ensembl chr 2:182,860,472...182,873,015

G

microtubule interacting and trafficking domain containing 1

increases expression

Vitamin K 3 results in increased expression of MITD1 mRNA

NCBI chr 9:40,113,943...40,125,280
Ensembl chr 9:40,113,946...40,125,289

G

Mix paired-like homeobox 1

affects expression

Vitamin K 3 affects the expression of MIXL1 mRNA

NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065

G

MLX interacting protein

affects expression

Vitamin K 3 affects the expression of MLXIP mRNA

NCBI chr12:33,128,524...33,192,300
Ensembl chr12:33,128,520...33,192,374

G

monocyte to macrophage differentiation-associated

affects expression

Vitamin K 3 affects the expression of MMD mRNA

NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528

G

matrix metallopeptidase 2

decreases expression

Vitamin K 3 results in decreased expression of MMP2 protein

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 9

decreases expression

Vitamin K 3 results in decreased expression of MMP9 protein

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

MAX network transcriptional repressor

affects expression

Vitamin K 3 affects the expression of MNT mRNA

NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835

G

mannosyl-oligosaccharide glucosidase

affects expression

Vitamin K 3 affects the expression of MOGS mRNA

NCBI chr 4:115,621,623...115,625,026
Ensembl chr 4:115,621,623...115,625,032

G

MORC family CW-type zinc finger 4

affects expression

Vitamin K 3 affects the expression of MORC4 mRNA

NCBI chr X:103,477,366...103,529,026
Ensembl chr X:103,480,603...103,528,956

G

modulator of smoothened

affects expression

Vitamin K 3 affects the expression of MOSMO mRNA

NCBI chr 1:175,217,680...175,288,521
Ensembl chr 1:175,217,545...175,288,334

G

mitochondrial pyruvate carrier 2

affects expression

Vitamin K 3 affects the expression of MPC2 mRNA

NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664

G

MPN domain containing

affects expression

Vitamin K 3 affects the expression of MPND mRNA

NCBI chr 9:839,473...846,446
Ensembl chr 9:840,143...846,439

G

MRN complex interacting protein

affects expression

Vitamin K 3 affects the expression of MRNIP mRNA

NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469

G

mitochondrial ribosomal protein L33

affects expression

Vitamin K 3 affects the expression of MRPL33 mRNA

NCBI chr 6:24,825,800...24,833,994
Ensembl chr 6:24,825,827...24,833,834

G

mitochondrial ribosomal protein L38

increases expression

Vitamin K 3 results in increased expression of MRPL38 mRNA

NCBI chr10:101,365,353...101,372,159
Ensembl chr10:101,365,353...101,372,171

G

mitochondrial ribosomal protein S12

affects expression

Vitamin K 3 affects the expression of MRPS12 mRNA

NCBI chr 1:84,025,896...84,028,896
Ensembl chr 1:84,025,899...84,028,780

G

magnesium transporter MRS2

affects expression

Vitamin K 3 affects the expression of MRS2 mRNA

NCBI chr17:40,063,924...40,087,073
Ensembl chr17:40,063,962...40,081,887

G

mutS homolog 2

affects expression
multiple interactions

Vitamin K 3 affects the expression of MSH2 mRNA
MSH2 protein inhibits the reaction [POLK protein results in decreased susceptibility to Vitamin K 3]

PMID:20044591 PMID:31294882

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

G

mutS homolog 6

affects expression

Vitamin K 3 affects the expression of MSH6 mRNA

NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956

G

microseminoprotein, beta

affects expression

Vitamin K 3 affects the expression of MSMB mRNA

NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123

G

methionine sulfoxide reductase B2

affects expression

Vitamin K 3 affects the expression of MSRB2 mRNA

NCBI chr17:81,974,378...82,000,044
Ensembl chr17:81,974,196...82,000,043

G

metallothionein 1

increases expression

Vitamin K 3 results in increased expression of MT1 mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 1, pseudogene 3

affects expression

Vitamin K 3 affects the expression of MT1E mRNA

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

increases expression

Vitamin K 3 results in increased expression of MT2A mRNA

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

metastasis associated 1 family, member 2

affects expression

Vitamin K 3 affects the expression of MTA2 mRNA

NCBI chr 1:205,838,181...205,846,903
Ensembl chr 1:205,837,964...205,846,946

G

mitochondrial amidoxime reducing component 1

affects expression

Vitamin K 3 affects the expression of MTARC1 mRNA

NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796

G

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

affects expression

Vitamin K 3 affects the expression of MTHFD1 mRNA

NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372

G

max dimerization protein 1

affects expression

Vitamin K 3 affects the expression of MXD1 mRNA

NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751

G

myeloid-associated differentiation marker

affects expression

Vitamin K 3 affects the expression of MYADM mRNA

NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035

G

MYC proto-oncogene, bHLH transcription factor

decreases expression
affects expression

Vitamin K 3 results in decreased expression of MYC
Vitamin K 3 affects the expression of MYC mRNA

PMID:10231603 PMID:20044591

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

myosin light chain 6

affects expression

Vitamin K 3 affects the expression of MYL6 mRNA

NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791

G

myosin light chain kinase

affects expression

Vitamin K 3 affects the expression of MYLK mRNA

NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261

G

myosin X

affects expression

Vitamin K 3 affects the expression of MYO10 mRNA

NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030

G

myosin XIX

affects expression

Vitamin K 3 affects the expression of MYO19 mRNA

NCBI chr10:69,753,082...69,782,450
Ensembl chr10:69,753,068...69,782,450

G

myelin regulatory factor

affects expression

Vitamin K 3 affects the expression of MYRF mRNA

NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157

G

Nedd4 binding protein 3

affects expression

Vitamin K 3 affects the expression of N4BP3 mRNA

NCBI chr10:35,898,031...35,906,704
Ensembl chr10:35,899,096...35,907,001

G

Ngfi-A binding protein 1

affects expression

Vitamin K 3 affects the expression of NAB1 mRNA

NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098

G

nucleic acid binding protein 1

affects expression

Vitamin K 3 affects the expression of NABP1 mRNA

NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107

G

NACC family member 2

affects expression

Vitamin K 3 affects the expression of NACC2 mRNA

NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660

G

N-acetyl-alpha-glucosaminidase

affects expression

Vitamin K 3 affects the expression of NAGLU mRNA

NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972

G

non-SMC condensin I complex, subunit G

affects expression

Vitamin K 3 affects the expression of NCAPG mRNA

NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902

G

non-SMC condensin I complex, subunit H

affects expression

Vitamin K 3 affects the expression of NCAPH mRNA

NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180

G

neutrophil cytosolic factor 1

increases expression

Vitamin K 3 results in increased expression of NCF1 mRNA; Vitamin K 3 results in increased expression of NCF1 protein

PMID:16507596 PMID:25270620

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

G

neutrophil cytosolic factor 2

increases expression

Vitamin K 3 results in increased expression of NCF2 protein

NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277

G

nuclear receptor co-repressor 2

affects expression

Vitamin K 3 affects the expression of NCOR2 mRNA

NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319

G

neuronal calcium sensor 1

affects expression

Vitamin K 3 affects the expression of FREQ mRNA

NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829

G

nicastrin

affects expression

Vitamin K 3 affects the expression of NCSTN mRNA

NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454

G

NDC1 transmembrane nucleoporin

affects expression

Vitamin K 3 affects the expression of NDC1 mRNA

NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291

G

NDC80 kinetochore complex component

affects expression

Vitamin K 3 affects the expression of NDC80 mRNA

NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924

G

nudE neurodevelopment protein 1

affects expression

Vitamin K 3 affects the expression of NDE1 mRNA

NCBI chr10:839,788...883,946
Ensembl chr10:839,788...883,869

G

N-myc downstream regulated 1

affects expression

Vitamin K 3 affects the expression of NDRG1 mRNA

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NADH:ubiquinone oxidoreductase subunit B1

affects expression

Vitamin K 3 affects the expression of NDUFB1 mRNA

NCBI chr 6:121,115,649...121,124,055

G

NADH:ubiquinone oxidoreductase core subunit S2

affects expression

Vitamin K 3 affects the expression of NDUFS2 mRNA

NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420

G

NECAP endocytosis associated 1

affects expression

Vitamin K 3 affects the expression of NECAP1 mRNA

NCBI chr 4:156,103,935...156,119,068
Ensembl chr 4:156,103,988...156,119,068

G

neogenin 1

affects expression

Vitamin K 3 affects the expression of NEO1 mRNA

NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348

G

neuroepithelial cell transforming 1

affects expression

Vitamin K 3 affects the expression of NET1 mRNA

NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

affects expression

Vitamin K 3 affects the expression of NF2 mRNA

NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667

G

NFE2 like bZIP transcription factor 2

multiple interactions
increases expression
affects response to substance
affects expression

[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Vitamin K 3
Vitamin K 3 results in increased expression of NFE2L2 mRNA
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Vitamin K 3
Vitamin K 3 affects the expression of NFE2L2 mRNA
NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Vitamin K 3]

PMID:19303893 PMID:19608619 PMID:20044591 PMID:20932822 PMID:23410634 More...

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NFE2 like bZIP transcription factor 3

affects expression

Vitamin K 3 affects the expression of NFE2L3 mRNA

NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629

G

nuclear factor kappa B subunit 1

affects expression
multiple interactions

Vitamin K 3 affects the expression of NFKB1 mRNA
Vitamin K 3 inhibits the reaction [Nicotine results in increased activity of NFKB1 protein]

PMID:16598845 PMID:20044591

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor alpha

affects expression

Vitamin K 3 affects the expression of NFKBIA mRNA

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor epsilon

affects expression

Vitamin K 3 affects the expression of NFKBIE mRNA

NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437

G

NFS1 cysteine desulfurase

affects expression

Vitamin K 3 affects the expression of NFS1 mRNA

NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666

G

NGG1 interacting factor 3 like 1

affects expression

Vitamin K 3 affects the expression of NIF3L1 mRNA

NCBI chr 9:59,980,101...60,001,490
Ensembl chr 9:59,979,799...60,000,131

G

NKD inhibitor of WNT signaling pathway 1

affects expression

Vitamin K 3 affects the expression of NKD1 mRNA

NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380

G

neuromedin B

affects expression

Vitamin K 3 affects the expression of NMB mRNA

NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190

G

NMD3 ribosome export adaptor

affects expression

Vitamin K 3 affects the expression of NMD3 mRNA

NCBI chr 2:154,012,973...154,038,466
Ensembl chr 2:154,013,020...154,039,259

G

nitric oxide associated 1

affects expression

Vitamin K 3 affects the expression of NOA1 mRNA

NCBI chr14:30,835,264...30,851,294
Ensembl chr14:30,835,247...30,851,293

G

nucleolar protein 7

affects expression

Vitamin K 3 affects the expression of NOL7 mRNA

NCBI chr17:21,303,650...21,306,924
Ensembl chr17:21,302,624...21,307,431

G

nucleolar and coiled-body phosphoprotein 1

affects expression

Vitamin K 3 affects the expression of NOLC1 mRNA

NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088

G

NOP16 nucleolar protein

affects expression

Vitamin K 3 affects the expression of NOP16 mRNA

NCBI chr17:10,022,950...10,027,867
Ensembl chr17:10,022,932...10,027,867

G

NOP56 ribonucleoprotein

affects expression

Vitamin K 3 affects the expression of NOP56 mRNA

NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841

G

NOP58 ribonucleoprotein

affects expression

Vitamin K 3 affects the expression of NOP58 mRNA

NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810

G

nitric oxide synthase 3

decreases activity

Vitamin K 3 results in decreased activity of NOS3 protein

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

nitric oxide synthase trafficking

affects expression

Vitamin K 3 affects the expression of NOSTRIN mRNA

NCBI chr 3:53,904,746...53,970,995
Ensembl chr 3:53,904,827...53,970,988

G

NADPH oxidase 1

increases expression

Vitamin K 3 results in increased expression of NOX1 mRNA; Vitamin K 3 results in increased expression of NOX1 protein

NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236

G

NADPH oxidase 4

increases expression

Vitamin K 3 results in increased expression of NOX4 mRNA; Vitamin K 3 results in increased expression of NOX4 protein

NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406

G

aminopeptidase puromycin sensitive

affects expression

Vitamin K 3 affects the expression of NPEPPS mRNA

NCBI chr10:82,191,454...82,273,967
Ensembl chr10:82,191,456...82,273,967

G

NPR3-like, GATOR1 complex subunit

affects expression

Vitamin K 3 affects the expression of NPRL3 mRNA

NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810

G

NAD(P)H quinone dehydrogenase 1

increases expression
multiple interactions
increases response to substance

Vitamin K 3 results in increased expression of NQO1 mRNA
NQO1 gene mutant form promotes the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide]
Dicumarol inhibits the reaction [NQO1 protein inhibits the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide]]; NAD promotes the reaction [NQO1 protein results in increased reduction of Vitamin K 3]; NADP promotes the reaction [NQO1 protein results in increased reduction of Vitamin K 3]; NQO1 protein inhibits the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide]
NQO1 gene mutant form results in increased susceptibility to Vitamin K 3

PMID:12414654 PMID:21859103 PMID:22846377 PMID:25270620 PMID:27558805

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

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N-ribosyldihydronicotinamide:quinone dehydrogenase 2

increases activity
increases reduction
decreases response to substance
affects response to substance
multiple interactions

NQO2 protein results in increased activity of Vitamin K 3
NQO2 protein results in increased reduction of Vitamin K 3
NQO2 gene mutant form results in decreased susceptibility to Vitamin K 3
NQO2 affects the susceptibility to Vitamin K 3
[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3; [NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3; Amodiaquine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; chrysoeriol inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; chrysoeriol inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Clozapine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; Mefenamic Acid inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; Melatonin inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; Melatonin inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; N-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; N-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]

PMID:12351651 PMID:17762829 PMID:20399199 PMID:21859103 PMID:29281794

NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320

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nuclear receptor subfamily 0, group B, member 2

affects expression

Vitamin K 3 affects the expression of NR0B2 mRNA

NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609

G

nuclear receptor subfamily 1, group H, member 4

affects expression

Vitamin K 3 affects the expression of NR1H4 mRNA

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

G

nuclear receptor subfamily 2, group F, member 2

affects expression

Vitamin K 3 affects the expression of NR2F2 mRNA

NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031

G

nuclear receptor subfamily 3, group C, member 1

affects expression

Vitamin K 3 affects the expression of NR3C1 mRNA

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

nuclear receptor subfamily 4, group A, member 1

affects expression
increases expression

Vitamin K 3 affects the expression of NR4A1 mRNA
Vitamin K 3 results in increased expression of NR4A1 mRNA

PMID:12414654 PMID:20044591

NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297

G

NSE4 homolog A, SMC5-SMC6 complex component

affects expression

Vitamin K 3 affects the expression of NSMCE4A mRNA

NCBI chr 1:185,102,075...185,109,166
Ensembl chr 1:185,094,360...185,109,166

G

NOP2/Sun RNA methyltransferase 2

affects expression

Vitamin K 3 affects the expression of NSUN2 mRNA

NCBI chr 1:33,662,139...33,685,887
Ensembl chr 1:33,662,139...33,685,862

G

neurotrophin 3

affects expression

Vitamin K 3 affects the expression of NTF3 mRNA

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

G

neurotrophic receptor tyrosine kinase 1

increases phosphorylation

Vitamin K 3 analog results in increased phosphorylation of NTRK1 protein

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

NudC domain containing 2

affects expression

Vitamin K 3 affects the expression of NUDCD2 mRNA

NCBI chr10:25,163,247...25,168,738
Ensembl chr10:25,163,220...25,168,738

G

nudix hydrolase 22

affects expression

Vitamin K 3 affects the expression of NUDT22 mRNA

NCBI chr 1:204,182,797...204,186,421
Ensembl chr 1:204,182,802...204,186,280

G

nudix hydrolase 6

affects expression

Vitamin K 3 affects the expression of NUDT6 mRNA

NCBI chr 2:120,289,908...120,306,197
Ensembl chr 2:120,290,847...120,306,230

G

NUMB, endocytic adaptor protein

decreases expression

Vitamin K 3 results in decreased expression of NUMB protein

NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354

G

nucleoporin 107

affects expression

Vitamin K 3 affects the expression of NUP107 mRNA

NCBI chr 7:53,353,740...53,398,345
Ensembl chr 7:53,353,743...53,398,370

G

nucleoporin 160

affects expression

Vitamin K 3 affects the expression of NUP160 mRNA

NCBI chr 3:76,665,786...76,729,296
Ensembl chr 3:76,665,786...76,724,565

G

ornithine aminotransferase

affects expression

Vitamin K 3 affects the expression of OAT mRNA

NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682

G

ornithine decarboxylase antizyme 1

affects expression

Vitamin K 3 affects the expression of OAZ1 mRNA

NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310

G

occludin/ELL domain containing 1

affects expression

Vitamin K 3 affects the expression of OCEL1 mRNA

NCBI chr16:18,042,037...18,045,080
Ensembl chr16:18,043,309...18,045,078

G

ornithine decarboxylase 1

affects expression

Vitamin K 3 affects the expression of ODC1 mRNA

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

G

oxoglutarate dehydrogenase L

affects expression

Vitamin K 3 affects the expression of OGDHL mRNA

NCBI chr16:7,578,343...7,604,385
Ensembl chr16:7,578,367...7,604,386

G

2-oxoglutarate and iron-dependent oxygenase domain containing 3

affects expression

Vitamin K 3 affects the expression of OGFOD3 mRNA

NCBI chr10:106,452,334...106,480,632
Ensembl chr10:106,452,329...106,480,134

G

8-oxoguanine DNA glycosylase

increases response to substance
increases expression

OGG1 protein SNP results in increased susceptibility to Vitamin K 3
Vitamin K 3 results in increased expression of OGG1 mRNA

PMID:17651912 PMID:23410634

NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766

G

O-linked N-acetylglucosamine (GlcNAc) transferase

affects expression

Vitamin K 3 affects the expression of OGT mRNA

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

G

ORMDL sphingolipid biosynthesis regulator 2

affects expression

Vitamin K 3 affects the expression of ORMDL2 mRNA

NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907

G

oxidative stress responsive serine-rich 1

affects expression

Vitamin K 3 affects the expression of OSER1 mRNA

NCBI chr 3:152,066,975...152,085,180
Ensembl chr 3:152,066,975...152,085,149

G

oxidative stress induced growth inhibitor 1

increases expression
affects expression

Vitamin K 3 results in increased expression of OSGIN1 mRNA
Vitamin K 3 affects the expression of OSGIN1 mRNA

PMID:12414654 PMID:23410634

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

ovo like transcriptional repressor 1

affects expression

Vitamin K 3 affects the expression of OVOL1 mRNA

NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831

G

poly(A) binding protein, cytoplasmic 1

affects expression

Vitamin K 3 affects the expression of PABPC1 mRNA

NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744

G

phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

affects expression

Vitamin K 3 affects the expression of PAICS mRNA

NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635

G

palladin, cytoskeletal associated protein

affects expression

Vitamin K 3 affects the expression of PALLD mRNA

NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337

G

peptidylglycine alpha-amidating monooxygenase

affects expression

Vitamin K 3 affects the expression of PAM mRNA

NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965

G

Pannexin 1

increases expression

Vitamin K 3 results in increased expression of PANX1 mRNA

NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774

G

poly (ADP-ribose) glycohydrolase

multiple interactions
affects response to substance

benzamide inhibits the reaction [PARG affects the susceptibility to Vitamin K 3]

NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273

G

poly (ADP-ribose) polymerase 1

multiple interactions
affects response to substance

[sodium arsenite co-treated with Vitamin K 3] results in increased cleavage of PARP1 protein
PARP1 protein affects the susceptibility to Vitamin K 3

PMID:19082730 PMID:21124846

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

pro-apoptotic WT1 regulator

affects expression

Vitamin K 3 affects the expression of PAWR mRNA

NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028

G

PAX interacting protein 1

affects expression

Vitamin K 3 affects the expression of PAXIP1 mRNA

NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548

G

poly(rC) binding protein 1

affects expression

Vitamin K 3 affects the expression of PCBP1 mRNA

NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500

G

propionyl-CoA carboxylase subunit alpha

affects expression

Vitamin K 3 affects the expression of PCCA mRNA

NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266

G

phosphoenolpyruvate carboxykinase 1

affects expression

Vitamin K 3 affects the expression of PCK1 mRNA

NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191

G

PCNA clamp associated factor

affects expression

Vitamin K 3 affects the expression of PCLAF mRNA

NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994

G

proliferating cell nuclear antigen

increases expression
affects expression
decreases expression
multiple interactions

Vitamin K 3 results in increased expression of PCNA protein
Vitamin K 3 affects the expression of PCNA mRNA
Vitamin K 3 results in decreased expression of PCNA protein
Alpha-Amanitin inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein]; Cycloheximide inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein]; Dactinomycin inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein]

PMID:20044591 PMID:20829426 PMID:21533478

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

prenylcysteine oxidase 1 like

affects expression

Vitamin K 3 affects the expression of PCYOX1L mRNA

NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327

G

programmed cell death 4

affects expression

Vitamin K 3 affects the expression of PDCD4 mRNA

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

G

protein disulfide isomerase family A, member 5

affects expression

Vitamin K 3 affects the expression of PDIA5 mRNA

NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084

G

podoplanin

increases expression

Vitamin K 3 results in increased expression of PDPN mRNA

NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656

G

p53 and DNA damage regulated 1

affects expression

Vitamin K 3 affects the expression of PDRG1 mRNA

NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858

G

pyridoxal-dependent decarboxylase domain containing 1

affects expression

Vitamin K 3 affects the expression of PDXDC1 mRNA

NCBI chr10:2,025,056...2,113,712
Ensembl chr10:2,025,360...2,113,520

G

PDZ domain containing 1

affects expression

Vitamin K 3 affects the expression of PDZK1 mRNA

NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514

G

peptidase D

affects expression

Vitamin K 3 affects the expression of PEPD mRNA

NCBI chr 1:87,536,650...87,681,233
Ensembl chr 1:87,536,609...87,681,231

G

period circadian regulator 2

affects expression

Vitamin K 3 affects the expression of PER2 mRNA

NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459

G

p53 apoptosis effector related to PMP22

increases expression

Vitamin K 3 results in increased expression of PERP mRNA

NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511

G

phosphofructokinase, platelet

decreases expression

Vitamin K 3 results in decreased expression of PFKP mRNA

NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018

G

post-GPI attachment to proteins 6

affects expression

Vitamin K 3 affects the expression of PGAP6 mRNA

NCBI chr10:15,138,918...15,148,431
Ensembl chr10:15,138,959...15,148,431

G

phosphogluconate dehydrogenase

increases expression

Vitamin K 3 results in increased expression of PGD mRNA

NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778

G

protein geranylgeranyltransferase type I subunit beta

increases expression

Vitamin K 3 results in increased expression of PGGT1B mRNA

NCBI chr18:38,952,147...38,995,656
Ensembl chr18:38,952,914...38,995,503

G

phosphoglycerate kinase 1

affects expression

Vitamin K 3 affects the expression of PGK1 mRNA

NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418

G

progesterone receptor membrane component 1

increases expression

Vitamin K 3 results in increased expression of PGRMC1 mRNA

NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682

G

prohibitin 1

affects expression

Vitamin K 3 affects the expression of PHB1 mRNA

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

G

PHD finger protein 10

affects expression

Vitamin K 3 affects the expression of PHF10 mRNA

NCBI chr 1:55,952,249...55,968,994
Ensembl chr 1:55,952,253...55,969,038

G

PHD finger protein 21A

decreases expression

Vitamin K 3 results in decreased expression of PHF21A mRNA

NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865

G

pleckstrin homology-like domain, family A, member 1

affects expression

Vitamin K 3 affects the expression of PHLDA1 mRNA

NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861

G

pleckstrin homology-like domain, family A, member 2

affects expression

Vitamin K 3 affects the expression of PHLDA2 mRNA

PMID:20044591 PMID:23410634

NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta

affects expression

Vitamin K 3 affects the expression of PIK3C2B mRNA

NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612

G

PICALM interacting mitotic regulator

affects expression

Vitamin K 3 affects the expression of PIMREG mRNA

NCBI chr10:56,669,603...56,674,540
Ensembl chr10:56,669,675...56,674,791

G

paired-like homeodomain 2

affects expression

Vitamin K 3 affects the expression of PITX2 mRNA

NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293

G

phospholipase A2, group XIIB

affects expression

Vitamin K 3 affects the expression of PLA2G12B mRNA

NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743

G

phospholipase A2 group VII

increases expression

Vitamin K 3 results in increased expression of PLA2G7 mRNA

NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476

G

phospholipase A2 receptor 1

increases expression

Vitamin K 3 results in increased expression of PLA2R1 mRNA

NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660

G

PLAG1 like zinc finger 2

affects expression

Vitamin K 3 affects the expression of PLAGL2 mRNA

NCBI chr 3:141,695,322...141,708,516
Ensembl chr 3:141,695,322...141,708,503

G

phospholipase B domain containing 1

affects expression

Vitamin K 3 affects the expression of PLBD1 mRNA

NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277

G

phospholipase C, epsilon 1

affects expression

Vitamin K 3 affects the expression of PLCE1 mRNA

NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438

G

phospholipase D family, member 3

affects expression

Vitamin K 3 affects the expression of PLD3 mRNA

NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072

G

pleckstrin homology domain containing A1

affects expression

Vitamin K 3 affects the expression of PLEKHA1 mRNA

NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156

G

pleckstrin homology domain containing A6

affects expression

Vitamin K 3 affects the expression of PLEKHA6 mRNA

NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673

G

pleckstrin homology domain containing O1

affects expression

Vitamin K 3 affects the expression of PLEKHO1 mRNA

NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785

G

pleckstrin homology domain containing O2

affects expression

Vitamin K 3 affects the expression of PLEKHO2 mRNA

NCBI chr 8:66,079,106...66,105,283
Ensembl chr 8:66,078,448...66,105,266

G

polo-like kinase 1

decreases expression

Vitamin K 3 results in decreased expression of PLK1 mRNA

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

G

polo-like kinase 3

affects expression

Vitamin K 3 affects the expression of PLK3 mRNA

PMID:20044591 PMID:23410634

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

phospholipid phosphatase 1

affects expression

Vitamin K 3 affects the expression of PLPP1 mRNA

NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268

G

phorbol-12-myristate-13-acetate-induced protein 1

affects expression

Vitamin K 3 affects the expression of PMAIP1 mRNA

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

prostate transmembrane protein, androgen induced 1

affects expression

Vitamin K 3 affects the expression of PMEPA1 mRNA

NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454

G

peptidase, mitochondrial processing subunit beta

affects expression

Vitamin K 3 affects the expression of PMPCB mRNA

NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367

G

pinin, desmosome associated protein

affects expression

Vitamin K 3 affects the expression of PNN mRNA

NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889

G

purine nucleoside phosphorylase

affects expression

Vitamin K 3 affects the expression of PNP mRNA

NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986

G

polyribonucleotide nucleotidyltransferase 1

affects expression

Vitamin K 3 affects the expression of PNPT1 mRNA

NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696

G

podocalyxin-like

affects expression

Vitamin K 3 affects the expression of PODXL mRNA

NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899

G

DNA polymerase delta 4, accessory subunit

affects expression

Vitamin K 3 affects the expression of POLD4 mRNA

NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401

G

DNA polymerase epsilon 2, accessory subunit

decreases expression

Vitamin K 3 results in decreased expression of POLE2 mRNA

NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305

G

DNA polymerase kappa

multiple interactions

MSH2 protein inhibits the reaction [POLK protein results in decreased susceptibility to Vitamin K 3]

NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313

G

RNA polymerase I and III subunit C

affects expression

Vitamin K 3 affects the expression of POLR1C mRNA

NCBI chr 9:14,735,740...14,739,852
Ensembl chr 9:14,735,714...14,739,852

G

RNA polymerase III subunit E

affects expression

Vitamin K 3 affects the expression of POLR3E mRNA

NCBI chr 1:175,466,091...175,494,679
Ensembl chr 1:175,466,127...175,494,667

G

paraoxonase 3

affects expression

Vitamin K 3 affects the expression of PON3 mRNA

NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855

G

POP7 homolog, ribonuclease P/MRP subunit

affects expression

Vitamin K 3 affects the expression of POP7 mRNA

NCBI chr12:19,189,384...19,190,425
Ensembl chr12:19,189,138...19,190,674

G

cytochrome p450 oxidoreductase

increases expression
multiple interactions

Vitamin K 3 results in increased expression of POR mRNA
NADP promotes the reaction [POR protein results in increased reduction of Vitamin K 3]; POR protein promotes the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide]

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

PPARG coactivator 1 beta

affects expression

Vitamin K 3 affects the expression of PPARGC1B mRNA

NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194

G

phosphopantothenoylcysteine synthetase

affects expression

Vitamin K 3 affects the expression of PPCS mRNA

NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933

G

pancreatic progenitor cell differentiation and proliferation factor

affects expression

Vitamin K 3 affects the expression of PPDPF mRNA

NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036

G

peptidylprolyl isomerase C

affects expression

Vitamin K 3 affects the expression of PPIC mRNA

NCBI chr18:46,842,410...46,855,016
Ensembl chr18:46,842,409...46,855,017

G

peptidylprolyl isomerase F

affects expression

Vitamin K 3 affects the expression of PPIF mRNA

NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913

G

peptidylprolyl isomerase like 1

affects expression

Vitamin K 3 affects the expression of PPIL1 mRNA

NCBI chr20:7,302,292...7,322,349
Ensembl chr20:7,302,621...7,322,354

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

increases expression

Vitamin K 3 results in increased expression of PPM1D mRNA

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein phosphatase 1, regulatory subunit 15A

affects expression

Vitamin K 3 affects the expression of PPP1R15A mRNA

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

protein phosphatase 1, regulatory subunit 16A

affects expression

Vitamin K 3 affects the expression of PPP1R16A mRNA

NCBI chr 7:108,391,664...108,414,812
Ensembl chr 7:108,391,656...108,419,509

G

protein phosphatase 1, regulatory subunit 26

affects expression

Vitamin K 3 affects the expression of PPP1R26 mRNA

NCBI chr 3:11,781,504...11,790,076
Ensembl chr 3:11,781,295...11,790,073

G

protein phosphatase 1, regulatory subunit 3C

affects expression

Vitamin K 3 affects the expression of PPP1R3C mRNA

NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961

G

protein phosphatase 1, regulatory subunit 9A

affects expression

Vitamin K 3 affects the expression of PPP1R9A mRNA

NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907

G

protein phosphatase 2 catalytic subunit beta

increases expression

Vitamin K 3 results in increased expression of PPP2CB mRNA

NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576

G

protein phosphatase 3 catalytic subunit gamma

affects expression

Vitamin K 3 affects the expression of PPP3CC mRNA

NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832

G

PPARG related coactivator 1

affects expression

Vitamin K 3 affects the expression of PPRC1 mRNA

NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587

G

peroxiredoxin 1

increases expression

Vitamin K 3 results in increased expression of PRDX1 mRNA

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

prolyl endopeptidase

affects expression

Vitamin K 3 affects the expression of PREP mRNA

NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466

G

protein kinase AMP-activated non-catalytic subunit beta 2

affects expression
decreases expression

Vitamin K 3 affects the expression of PRKAB2 mRNA
Vitamin K 3 results in decreased expression of PRKAB2 mRNA

PMID:20044591 PMID:25270620

NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872

G

protein kinase cGMP-dependent 1

increases oxidation
multiple interactions

Vitamin K 3 results in increased oxidation of PRKG1 protein
Resveratrol promotes the reaction [Vitamin K 3 results in increased oxidation of PRKG1 protein]

NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080

G

protein arginine methyltransferase 8

decreases expression

Vitamin K 3 results in decreased expression of PRMT8 mRNA

NCBI chr 4:160,535,813...160,618,193
Ensembl chr 4:160,535,813...160,617,930

G

serine protease 22

affects expression

Vitamin K 3 affects the expression of PRSS22 mRNA

NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863

G

phosphoserine aminotransferase 1

affects expression

Vitamin K 3 affects the expression of PSAT1 mRNA

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 20S subunit alpha 6

affects expression

Vitamin K 3 affects the expression of PSMA6 mRNA

NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554

G

proteasome 20S subunit beta 3

affects expression

Vitamin K 3 affects the expression of PSMB3 mRNA

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 26S subunit, non-ATPase 12

increases expression

Vitamin K 3 results in increased expression of PSMD12 mRNA

NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287

G

proteasome assembly chaperone 1

affects expression

Vitamin K 3 affects the expression of PSMG1 mRNA

NCBI chr11:35,276,080...35,285,541
Ensembl chr11:35,276,011...35,285,622

G

phosphoserine phosphatase

affects expression

Vitamin K 3 affects the expression of PSPH mRNA

NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074

G

Pentatricopeptide repeat domain 3

affects expression

Vitamin K 3 affects the expression of PTCD3 mRNA

NCBI chr 4:103,922,440...103,957,445
Ensembl chr 4:103,920,566...103,957,538

G

prostaglandin reductase 1

increases expression

Vitamin K 3 results in increased expression of PTGR1 mRNA

PMID:23410634 PMID:25270620

NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666

G

protein tyrosine phosphatase, non-receptor type 11

affects expression

Vitamin K 3 affects the expression of PTPN11 mRNA

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

G

protein tyrosine phosphatase, receptor type, A

affects expression

Vitamin K 3 affects the expression of PTPRA mRNA

NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728

G

protein tyrosine phosphatase, receptor type, M

affects expression

Vitamin K 3 affects the expression of PTPRM mRNA

NCBI chr 9:106,639,573...107,343,698
Ensembl chr 9:106,639,573...107,343,698

G

peptidyl-tRNA hydrolase 1 homolog

affects expression

Vitamin K 3 affects the expression of PTRH1 mRNA

NCBI chr 3:16,064,867...16,071,098
Ensembl chr 3:16,064,880...16,070,648

G

pseudouridine 5'-phosphatase

affects expression

Vitamin K 3 affects the expression of PUDP mRNA

NCBI chr18:43,878,374...43,880,756
Ensembl chr18:43,878,080...43,880,791

G

poly-U binding splicing factor 60

affects expression

Vitamin K 3 affects the expression of PUF60 mRNA

NCBI chr 7:107,782,799...107,793,759
Ensembl chr 7:107,782,770...107,794,531

G

pumilio RNA-binding family member 3

affects expression

Vitamin K 3 affects the expression of PUM3 mRNA

NCBI chr 1:225,074,332...225,113,995
Ensembl chr 1:225,074,333...225,114,025

G

purine rich element binding protein A

decreases expression

Vitamin K 3 results in decreased expression of PURA mRNA

NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513

G

pseudouridine synthase 7

affects expression

Vitamin K 3 affects the expression of PUS7 mRNA

NCBI chr 4:11,360,169...11,401,139
Ensembl chr 4:11,360,188...11,401,172

G

peroxisomal membrane protein 4

affects expression

Vitamin K 3 affects the expression of PXMP4 mRNA

NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651

G

2-phosphoxylose phosphatase 1

affects expression

Vitamin K 3 affects the expression of PXYLP1 mRNA

NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064

G

R3H domain containing 2

affects expression

Vitamin K 3 affects the expression of R3HDM2 mRNA

NCBI chr 7:63,212,519...63,340,574
Ensembl chr 7:63,232,346...63,340,540

G

RAB11 family interacting protein 1

affects expression

Vitamin K 3 affects the expression of RAB11FIP1 mRNA

NCBI chr16:64,886,902...64,917,491
Ensembl chr16:64,884,676...64,917,491

G

RAB11 family interacting protein 4

affects expression

Vitamin K 3 affects the expression of RAB11FIP4 mRNA

NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759

G

RAB3 GTPase activating protein catalytic subunit 1

affects expression

Vitamin K 3 affects the expression of RAB3GAP1 mRNA

NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169

G

RAB5C, member RAS oncogene family

affects expression

Vitamin K 3 affects the expression of RAB5C mRNA

NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103

G

receptor for activated C kinase 1

affects expression

Vitamin K 3 affects the expression of RACK1 mRNA

NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975

G

RAD23 homolog B, nucleotide excision repair protein

affects expression

Vitamin K 3 affects the expression of RAD23B mRNA

NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319

G

RAD51 recombinase

affects expression

Vitamin K 3 affects the expression of RAD51 mRNA

NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035

G

retinoic acid induced 1

affects expression

Vitamin K 3 affects the expression of RAI1 mRNA

NCBI chr10:44,913,231...45,008,232
Ensembl chr10:44,947,909...45,008,232

G

ral guanine nucleotide dissociation stimulator like 1

affects expression

Vitamin K 3 affects the expression of RGL1 mRNA

NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191

G

receptor activity modifying protein 1

affects expression

Vitamin K 3 affects the expression of RAMP1 mRNA

NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151

G

RAN binding protein 1

affects expression

Vitamin K 3 affects the expression of RANBP1 mRNA

NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838

G

RAN binding protein 9

affects expression

Vitamin K 3 affects the expression of RANBP9 mRNA

NCBI chr17:21,220,807...21,303,009
Ensembl chr17:21,220,618...21,303,004

G

Rap1 GTPase-activating protein

increases expression

Vitamin K 3 results in increased expression of RAP1GAP mRNA

NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253

G

ras related dexamethasone induced 1

affects expression

Vitamin K 3 affects the expression of RASD1 mRNA

NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186

G

RAS-like family 11 member A

affects expression

Vitamin K 3 affects the expression of RASL11A mRNA

NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576

G

Ras association domain family member 1

affects expression

Vitamin K 3 affects the expression of RASSF1 mRNA

NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164

G

RB transcriptional corepressor 1

increases expression

Vitamin K 3 results in increased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RB binding protein 4, chromatin remodeling factor

affects expression

Vitamin K 3 affects the expression of RBBP4 mRNA

NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284

G

RB binding protein 6, ubiquitin ligase

affects expression

Vitamin K 3 affects the expression of RBBP6 mRNA

NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678

G

RNA binding motif protein 17

affects expression

Vitamin K 3 affects the expression of RBM17 mRNA

NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014

G

RNA binding motif, single stranded interacting protein 1

affects expression

Vitamin K 3 affects the expression of RBMS1 mRNA

NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376

G

RNA binding motif protein, X-linked

affects expression

Vitamin K 3 affects the expression of RBMX mRNA

NCBI chr X:135,305,237...135,314,806
Ensembl chr X:135,305,325...135,314,743

G

recombination signal binding protein for immunoglobulin kappa J region

decreases expression

Vitamin K 3 results in decreased expression of RBPJ mRNA

NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353

G

regulator of calcineurin 1

increases phosphorylation

Vitamin K 3 results in increased phosphorylation of RCAN1 protein

NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045

G

reticulocalbin 1

affects expression

Vitamin K 3 affects the expression of RCN1 mRNA

NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295

G

REST corepressor 3

affects expression

Vitamin K 3 affects the expression of RCOR3 mRNA

NCBI chr13:103,624,966...103,665,565
Ensembl chr13:103,624,971...103,665,565

G

receptor accessory protein 1

affects expression

Vitamin K 3 affects the expression of REEP1 mRNA

NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338

G

receptor accessory protein 4

affects expression

Vitamin K 3 affects the expression of REEP4 mRNA

NCBI chr15:45,620,317...45,623,524
Ensembl chr15:45,619,941...45,623,526

G

receptor accessory protein 6

affects expression

Vitamin K 3 affects the expression of REEP6 mRNA

NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

Vitamin K 3 inhibits the reaction [TNF protein affects the localization of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

affects expression

Vitamin K 3 affects the expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

reticulophagy regulator 1

affects expression

Vitamin K 3 affects the expression of RETREG1 mRNA

NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898

G

reticulophagy regulator family member 2

affects expression

Vitamin K 3 affects the expression of RETREG2 mRNA

NCBI chr 9:76,640,282...76,646,400
Ensembl chr 9:76,640,319...76,646,395

G

required for excision 1-B domain containing

affects expression

Vitamin K 3 affects the expression of REX1BD mRNA

NCBI chr16:18,922,050...18,924,521
Ensembl chr16:18,922,037...18,924,526

G

RNA exonuclease 2

affects expression

Vitamin K 3 affects the expression of REXO2 mRNA

NCBI chr 8:48,811,900...48,823,622
Ensembl chr 8:48,811,900...48,823,622

G

replication factor C subunit 4

affects expression

Vitamin K 3 affects the expression of RFC4 mRNA

NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122

G

regulator of cell cycle

affects expression

Vitamin K 3 affects the expression of RGCC mRNA

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

G

regulator of G-protein signaling 16

affects expression

Vitamin K 3 affects the expression of RGS16 mRNA

NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857

G

regulator of G-protein signaling 3

affects expression

Vitamin K 3 affects the expression of RGS3 mRNA

NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894

G

rhomboid domain containing 3

affects expression

Vitamin K 3 affects the expression of RHBDD3 mRNA

NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175

G

Rh family B glycoprotein

affects expression

Vitamin K 3 affects the expression of RHBG mRNA

NCBI chr 2:173,704,852...173,717,380
Ensembl chr 2:173,704,562...173,717,321

G

ras homolog family member A

multiple interactions
decreases prenylation

tempol inhibits the reaction [Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Vitamin K 3 results in decreased prenylation of RHOA protein]; Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

G

ras homolog family member C

affects expression

Vitamin K 3 affects the expression of RHOC mRNA

NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306

G

RIB43A domain with coiled-coils 2

affects expression

Vitamin K 3 affects the expression of RIBC2 mRNA

NCBI chr 7:116,242,863...116,257,868
Ensembl chr 7:116,242,863...116,257,863

G

RPTOR independent companion of MTOR, complex 2

affects expression

Vitamin K 3 affects the expression of RICTOR mRNA

NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426

G

RBPJ interacting and tubulin associated 1

affects expression

Vitamin K 3 affects the expression of RITA1 mRNA

NCBI chr12:35,950,090...35,953,960
Ensembl chr12:35,950,373...35,953,960

G

RecQ mediated genome instability 2

affects expression

Vitamin K 3 affects the expression of RMI2 mRNA

NCBI chr10:4,829,333...4,837,264
Ensembl chr10:4,830,553...4,837,235

G

ring finger protein 114

affects expression

Vitamin K 3 affects the expression of RNF114 mRNA

NCBI chr 3:156,222,487...156,234,263
Ensembl chr 3:156,222,498...156,234,256

G

ring finger protein 122

affects expression

Vitamin K 3 affects the expression of RNF122 mRNA

NCBI chr16:61,009,879...61,027,429
Ensembl chr16:61,009,879...61,027,448

G

ring finger protein 128

affects expression

Vitamin K 3 affects the expression of RNF128 mRNA

NCBI chr X:103,183,643...103,298,431
Ensembl chr X:103,183,831...103,298,423

G

ring finger protein 130

affects expression

Vitamin K 3 affects the expression of RNF130 mRNA

NCBI chr10:34,342,835...34,456,048
Ensembl chr10:34,342,830...34,456,062

G

ring finger protein 43

affects expression

Vitamin K 3 affects the expression of RNF43 mRNA

NCBI chr10:72,461,508...72,537,301
Ensembl chr10:72,464,348...72,536,977

G

ring finger protein 44

affects expression

Vitamin K 3 affects the expression of RNF44 mRNA

NCBI chr17:9,919,982...9,934,376
Ensembl chr17:9,919,993...9,932,193

G

retinal outer segment membrane protein 1

affects expression

Vitamin K 3 affects the expression of ROM1 mRNA

NCBI chr 1:205,824,050...205,826,058
Ensembl chr 1:205,824,052...205,826,175

G

replication protein A1

affects expression

Vitamin K 3 affects the expression of RPA1 mRNA

NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949

G

retinitis pigmentosa GTPase regulator

affects expression

Vitamin K 3 affects the expression of RPGR mRNA

NCBI chr X:12,566,447...12,628,171
Ensembl chr X:12,566,645...12,747,882

G

ribosomal protein L27A

affects expression

Vitamin K 3 affects the expression of RPL27A mRNA

NCBI chr 1:163,539,732...163,542,771

G

ribonuclease P/MRP subunit p25 like

affects expression

Vitamin K 3 affects the expression of RPP25L mRNA

NCBI chr 5:56,878,420...56,879,956
Ensembl chr 5:56,876,316...56,880,013

G

ribosomal protein S6 kinase A3

affects expression

Vitamin K 3 affects the expression of RPS6KA3 mRNA

NCBI chr X:35,517,306...35,623,296
Ensembl chr X:35,517,306...35,623,207

G

regulatory associated protein of MTOR, complex 1

affects expression

Vitamin K 3 affects the expression of RPTOR mRNA

NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983

G

RAS related 2

increases expression

Vitamin K 3 results in increased expression of RRAS2 mRNA

NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111

G

ribosome binding protein 1

affects expression

Vitamin K 3 affects the expression of RRBP1 mRNA

NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981

G

ribonucleotide reductase catalytic subunit M1

affects expression

Vitamin K 3 affects the expression of RRM1 mRNA

PMID:20044591 PMID:23410634

NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261

G

radical S-adenosyl methionine domain containing 1

affects expression

Vitamin K 3 affects the expression of RSAD1 mRNA

NCBI chr10:79,485,253...79,499,616
Ensembl chr10:79,489,909...79,499,573

G

arginine and serine rich protein 1

affects expression

Vitamin K 3 affects the expression of RSRP1 mRNA

NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523

G

RT1 class Ia, locus A2

affects expression

Vitamin K 3 affects the expression of HLA-E mRNA

NCBI chr20:4,870,939...4,910,183

G

RT1 class II, locus Ba

affects expression

Vitamin K 3 affects the expression of HLA-DQA1 mRNA

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

RT1 class II, locus Bb

affects expression

Vitamin K 3 affects the expression of HLA-DQB1 mRNA

NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597

G

retrotransposon Gag like 6

affects expression

Vitamin K 3 affects the expression of RTL6 mRNA

NCBI chr 7:115,684,812...115,689,897
Ensembl chr 7:115,684,739...115,690,052

G

RUS family member 1

affects expression

Vitamin K 3 affects the expression of RUSF1 mRNA

NCBI chr 1:182,852,257...182,881,652
Ensembl chr 1:182,852,262...182,880,732

G

retinoid X receptor alpha

affects expression

Vitamin K 3 affects the expression of RXRA mRNA

NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712

G

ryanodine receptor 1

affects expression

Vitamin K 3 affects the expression of RYR1 mRNA

NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812

G

S100 calcium binding protein A6

affects expression

Vitamin K 3 affects the expression of S100A6 mRNA

NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180

G

suppressor APC domain containing 2

affects expression

Vitamin K 3 affects the expression of SAPCD2 mRNA

NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546

G

SAM and SH3 domain containing 1

affects expression

Vitamin K 3 affects the expression of SASH1 mRNA

NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870

G

sterol-C5-desaturase

affects expression

Vitamin K 3 affects the expression of SC5D mRNA

NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273

G

SCAN domain-containing 1

affects expression

Vitamin K 3 affects the expression of SCAND1 mRNA

NCBI chr 3:144,818,615...144,819,479
Ensembl chr 3:144,818,611...144,820,025

G

SREBF chaperone

affects expression

Vitamin K 3 affects the expression of SCAP mRNA

NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666

G

secernin 2

affects expression

Vitamin K 3 affects the expression of SCRN2 mRNA

NCBI chr10:82,016,604...82,020,676
Ensembl chr10:82,016,649...82,020,675

G

SEC14-like lipid binding 4

increases expression

Vitamin K 3 results in increased expression of SEC14L4 mRNA

NCBI chr14:78,912,750...78,928,799
Ensembl chr14:78,912,750...78,956,099

G

SEC24 homolog B, COPII coat complex component

affects expression

Vitamin K 3 affects the expression of SEC24B mRNA

NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699

G

Sec61 translocon subunit gamma

affects expression

Vitamin K 3 affects the expression of SEC61G mRNA

NCBI chr14:90,899,766...90,906,143
Ensembl chr14:90,899,768...90,906,162

G

SEC63 homolog, protein translocation regulator

affects expression

Vitamin K 3 affects the expression of SEC63 mRNA

NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055

G

SEH1-like nucleoporin

affects expression

Vitamin K 3 affects the expression of SEH1L mRNA

NCBI chr18:61,346,986...61,369,987

G

selenoprotein P

affects expression

Vitamin K 3 affects the expression of SELENOP mRNA

NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852

G

selenoprotein S

affects expression

Vitamin K 3 affects the expression of SELENOS mRNA

NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833

G

selenoprotein W

affects expression

Vitamin K 3 affects the expression of SELENOW mRNA

NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724

G

semaphorin 4G

affects expression

Vitamin K 3 affects the expression of SEMA4G mRNA

NCBI chr 1:243,849,979...243,865,343
Ensembl chr 1:243,853,854...243,865,341

G

semaphorin 6A

affects expression

Vitamin K 3 affects the expression of SEMA6A mRNA

NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954

G

selenophosphate synthetase 2

affects expression

Vitamin K 3 affects the expression of SEPHS2 mRNA

NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497

G

Serpine1 mRNA binding protein 1

affects expression

Vitamin K 3 affects the expression of SERBP1 mRNA

NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813

G

serpin family B member 1A

affects expression

Vitamin K 3 affects the expression of SERPINB1 mRNA

NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102

G

serpin family B member 5

increases expression

Vitamin K 3 results in increased expression of SERPINB5 mRNA

NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756

G

SET domain containing 6, protein lysine methyltransferase

affects expression

Vitamin K 3 affects the expression of SETD6 mRNA

NCBI chr19:9,343,309...9,350,477
Ensembl chr19:9,347,458...9,350,453

G

serum/glucocorticoid regulated kinase 2

affects expression

Vitamin K 3 affects the expression of SGK2 mRNA

NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480

G

SH2 domain containing 5

affects expression

Vitamin K 3 affects the expression of SH2D5 mRNA

NCBI chr 5:150,469,738...150,480,615
Ensembl chr 5:150,467,728...150,479,955

G

SH3 domain binding glutamate-rich protein like 3

affects expression

Vitamin K 3 affects the expression of SH3BGRL3 mRNA

NCBI chr 5:146,354,152...146,355,525
Ensembl chr 5:146,354,152...146,355,331

G

SH3 and PX domains 2A

affects expression

Vitamin K 3 affects the expression of SH3PXD2A mRNA

NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166

G

SH3 domain containing ring finger 1

increases expression

Vitamin K 3 results in increased expression of SH3RF1 mRNA

NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644

G

SH3 and SYLF domain containing 1

affects expression

Vitamin K 3 affects the expression of SH3YL1 mRNA

NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858

G

SH3 and multiple ankyrin repeat domains 2

affects expression

Vitamin K 3 affects the expression of SHANK2 mRNA

NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394

G

siah E3 ubiquitin protein ligase 1

affects expression

Vitamin K 3 affects the expression of SIAH1 mRNA

NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808

G

SID1 transmembrane family, member 2

affects expression

Vitamin K 3 affects the expression of SIDT2 mRNA

NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700

G

salt-inducible kinase 1

affects expression

Vitamin K 3 affects the expression of SIK1 mRNA

NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991

G

SIN3-HDAC complex associated factor

affects expression

Vitamin K 3 affects the expression of SINHCAF mRNA

NCBI chr 4:181,888,301...181,913,294
Ensembl chr 4:181,888,312...181,910,276

G

signal-regulatory protein alpha

affects expression

Vitamin K 3 affects the expression of SIRPA mRNA

NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098

G

sirtuin 1

multiple interactions

[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of SIRT1 mRNA]]; Vitamin K 3 inhibits the reaction [sodium arsenite results in decreased degradation of SIRT1 mRNA]

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

spindle and kinetochore associated complex subunit 3

affects expression

Vitamin K 3 affects the expression of SKA3 mRNA

NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010

G

SKI-like proto-oncogene

decreases expression

Vitamin K 3 results in decreased expression of SKIL mRNA

NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080

G

signaling lymphocytic activation molecule family member 1

increases expression

Vitamin K 3 results in increased expression of SLAMF1 mRNA

NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497

G

stem-loop histone mRNA binding protein

affects expression

Vitamin K 3 affects the expression of SLBP mRNA

NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906

G

solute carrier family 10, member 3

affects expression

Vitamin K 3 affects the expression of SLC10A3 mRNA

NCBI chr X:152,154,757...152,158,563
Ensembl chr X:152,151,076...152,162,958

G

solute carrier family 12 member 7

affects expression

Vitamin K 3 affects the expression of SLC12A7 mRNA

NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302

G

solute carrier family 12, member 9

affects expression

Vitamin K 3 affects the expression of SLC12A9 mRNA

NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877

G

solute carrier family 15 member 4

affects expression

Vitamin K 3 affects the expression of SLC15A4 mRNA

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

G

solute carrier family 16 member 3

affects expression

Vitamin K 3 affects the expression of SLC16A3 mRNA

NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562

G

solute carrier family 17, member 2

affects expression

Vitamin K 3 affects the expression of SLC17A2 mRNA

NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,319,701...41,336,325

G

solute carrier family 19 member 3

affects expression

Vitamin K 3 affects the expression of SLC19A3 mRNA

NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337

G

solute carrier family 1 member 1

affects expression

Vitamin K 3 affects the expression of SLC1A1 mRNA

NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402

G

solute carrier family 20 member 1

affects expression

Vitamin K 3 affects the expression of SLC20A1 mRNA

NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051

G

solute carrier family 20 member 2

affects expression

Vitamin K 3 affects the expression of SLC20A2 mRNA

NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711

G

solute carrier family 22, member 23

affects expression

Vitamin K 3 affects the expression of SLC22A23 mRNA

NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790

G

solute carrier family 22 member 3

affects expression

Vitamin K 3 affects the expression of SLC22A3 mRNA

NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612

G

solute carrier family 25 member 3

affects expression

Vitamin K 3 affects the expression of SLC25A3 mRNA

NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727

G

solute carrier family 25 member 36

affects expression

Vitamin K 3 affects the expression of SLC25A36 mRNA

NCBI chr 8:97,659,848...97,693,735
Ensembl chr 8:97,662,127...97,693,703

G

solute carrier family 25 member 5

affects expression

Vitamin K 3 affects the expression of SLC25A5 mRNA

NCBI chr X:116,031,896...116,034,963
Ensembl chr X:116,031,803...116,034,967

G

solute carrier family 26 member 2

affects expression

Vitamin K 3 affects the expression of SLC26A2 mRNA

NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626

G

solute carrier family 27 member 2

affects expression

Vitamin K 3 affects the expression of SLC27A2 mRNA

PMID:20044591 PMID:23410634

NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208

G

solute carrier family 2 member 1

affects expression
decreases expression

Vitamin K 3 affects the expression of SLC2A1 mRNA
Vitamin K 3 results in decreased expression of SLC2A1 mRNA

PMID:20044591 PMID:25270620

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 3

decreases expression

Vitamin K 3 results in decreased expression of SLC2A3 mRNA

NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472

G

SLC2A4 regulator

affects expression

Vitamin K 3 affects the expression of SLC2A4RG mRNA

NCBI chr 3:168,493,975...168,497,616

G

solute carrier family 38, member 10

affects expression

Vitamin K 3 affects the expression of SLC38A10 mRNA

NCBI chr10:105,386,836...105,436,636
Ensembl chr10:105,386,836...105,436,636

G

solute carrier family 39 member 13

affects expression

Vitamin K 3 affects the expression of SLC39A13 mRNA

NCBI chr 3:77,039,411...77,047,528
Ensembl chr 3:77,037,565...77,049,226

G

solute carrier family 39 member 14

affects expression

Vitamin K 3 affects the expression of SLC39A14 mRNA

NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524

G

solute carrier family 44, member 4

affects expression

Vitamin K 3 affects the expression of SLC44A4 mRNA

NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215

G

solute carrier family 6 member 14

affects expression

Vitamin K 3 affects the expression of SLC6A14 mRNA

NCBI chr X:112,314,643...112,375,412
Ensembl chr X:112,314,691...112,375,096

G

solute carrier family 7 member 11

increases expression

Vitamin K 3 results in increased expression of SLC7A11 mRNA

PMID:12414654 PMID:23410634

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

sarcolemma associated protein

affects expression

Vitamin K 3 affects the expression of SLMAP mRNA

NCBI chr16:1,667,205...1,785,200
Ensembl chr16:1,667,208...1,785,149

G

SLX9 ribosome biogenesis factor

affects expression

Vitamin K 3 affects the expression of SLX9 mRNA

NCBI chr20:11,114,632...11,147,532
Ensembl chr20:11,114,589...11,147,521

G

SMAD family member 3

affects expression

Vitamin K 3 affects the expression of SMAD3 mRNA

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

G

SWI/SNF related BAF chromatin remodeling complex subunit C2

affects expression

Vitamin K 3 affects the expression of SMARCC2 mRNA

NCBI chr 7:881,844...910,090
Ensembl chr 7:881,421...909,978

G

structural maintenance of chromosomes 1A

affects expression

Vitamin K 3 affects the expression of SMC1A mRNA

PMID:20044591 PMID:20829426

NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056

G

structural maintenance of chromosomes 4

affects expression

Vitamin K 3 affects the expression of SMC4 mRNA

NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571

G

small integral membrane protein 19

affects expression

Vitamin K 3 affects the expression of SMIM19 mRNA

NCBI chr16:69,551,507...69,564,323
Ensembl chr16:69,553,916...69,567,245

G

small integral membrane protein 29

affects expression

Vitamin K 3 affects the expression of SMIM29 mRNA

NCBI chr20:5,618,845...5,620,856
Ensembl chr20:5,618,845...5,620,813

G

smoothened, frizzled class receptor

affects expression

Vitamin K 3 affects the expression of SMO mRNA

NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829

G

SPARC related modular calcium binding 2

affects expression

Vitamin K 3 affects the expression of SMOC2 mRNA

NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693

G

spermine oxidase

affects expression

Vitamin K 3 affects the expression of SMOX mRNA

NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710

G

sphingomyelin phosphodiesterase, acid-like 3A

affects expression

Vitamin K 3 affects the expression of SMPDL3A mRNA

NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567

G

SET and MYND domain containing 2

affects expression

Vitamin K 3 affects the expression of SMYD2 mRNA

NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576

G

snail family transcriptional repressor 1

affects expression
decreases expression

Vitamin K 3 affects the expression of SNAI1 mRNA
Vitamin K 3 results in decreased expression of SNAI1 protein

PMID:20044591 PMID:31238027

NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969

G

small nuclear ribonucleoprotein U5 subunit 200

affects expression

Vitamin K 3 affects the expression of SNRNP200 mRNA

NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182

G

small nuclear ribonucleoprotein U1 subunit 70

affects expression

Vitamin K 3 affects the expression of SNRNP70 mRNA

NCBI chr 1:95,856,038...95,876,434
Ensembl chr 1:95,856,036...95,876,392

G

small nuclear ribonucleoprotein D1 polypeptide

affects expression

Vitamin K 3 affects the expression of SNRPD1 mRNA

NCBI chr18:1,696,838...1,707,400
Ensembl chr18:1,696,852...1,708,256

G

syntrophin, alpha 1

affects expression

Vitamin K 3 affects the expression of SNTA1 mRNA

NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709

G

syntrophin, beta 1

affects expression

Vitamin K 3 affects the expression of SNTB1 mRNA

NCBI chr 7:87,060,926...87,329,315
Ensembl chr 7:87,060,926...87,329,315

G

sorting nexin 14

affects expression

Vitamin K 3 affects the expression of SNX14 mRNA

NCBI chr 8:89,283,673...89,390,597
Ensembl chr 8:89,298,114...89,390,580

G

sorting nexin 15

decreases expression

Vitamin K 3 results in decreased expression of SNX15 mRNA

NCBI chr 1:203,417,029...203,426,173
Ensembl chr 1:203,417,029...203,426,247

G

sorting nexin family member 21

affects expression

Vitamin K 3 affects the expression of SNX21 mRNA

NCBI chr 3:153,522,474...153,532,235
Ensembl chr 3:153,522,486...153,532,221

G

sorting nexin 9

affects expression

Vitamin K 3 affects the expression of SNX9 mRNA

NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036

G

sterol O-acyltransferase 2

affects expression

Vitamin K 3 affects the expression of SOAT2 mRNA

NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915

G

superoxide dismutase 1

multiple interactions
affects response to substance

[CAT protein co-treated with SOD1 protein] results in decreased susceptibility to Vitamin K 3
SOD1 protein affects the susceptibility to Vitamin K 3

PMID:10698074 PMID:12633745

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

decreases response to substance
increases response to substance
multiple interactions
increases activity

SOD2 protein results in decreased susceptibility to Vitamin K 3
SOD2 protein results in increased susceptibility to Vitamin K 3
[CAT protein co-treated with SOD2 protein] results in decreased susceptibility to Vitamin K 3
Vitamin K 3 results in increased activity of SOD2 protein
Acetaminophen inhibits the reaction [Vitamin K 3 results in increased activity of SOD2 protein]

PMID:12633745 PMID:14660625 PMID:15986238 PMID:19265712

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

sortilin related receptor 1

affects expression

Vitamin K 3 affects the expression of SORL1 mRNA

NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513

G

Sp5 transcription factor

affects expression

Vitamin K 3 affects the expression of SP5 mRNA

NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733

G

sperm associated antigen 5

affects expression

Vitamin K 3 affects the expression of SPAG5 mRNA

PMID:20044591 PMID:23410634

NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745

G

spermatogenesis associated 20

affects expression

Vitamin K 3 affects the expression of SPATA20 mRNA

NCBI chr10:79,427,525...79,435,472
Ensembl chr10:79,427,528...79,434,368

G

spindle apparatus coiled-coil protein 1

affects expression

Vitamin K 3 affects the expression of SPDL1 mRNA

NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127

G

sphingosine kinase 1

affects expression

Vitamin K 3 affects the expression of SPHK1 mRNA

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

G

serine peptidase inhibitor, Kazal type 1

affects expression

Vitamin K 3 affects the expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

sprouty RTK signaling antagonist 2

affects expression
decreases expression

Vitamin K 3 affects the expression of SPRY2 mRNA
Vitamin K 3 results in decreased expression of SPRY2 mRNA

PMID:20044591 PMID:25270620

NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009

G

sprouty RTK signaling antagonist 4

affects expression

Vitamin K 3 affects the expression of SPRY4 mRNA

NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004

G

splA/ryanodine receptor domain and SOCS box containing 2

affects expression

Vitamin K 3 affects the expression of SPSB2 mRNA

NCBI chr 4:157,613,404...157,615,293
Ensembl chr 4:157,613,401...157,615,284

G

sulfide quinone oxidoreductase

affects expression

Vitamin K 3 affects the expression of SQOR mRNA

NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778

G

sequestosome 1

increases expression

Vitamin K 3 results in increased expression of SQSTM1 mRNA

PMID:23410634 PMID:25270620

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

SLIT-ROBO Rho GTPase activating protein 2

affects expression

Vitamin K 3 affects the expression of SRGAP2 mRNA

NCBI chr13:42,745,956...42,967,091
Ensembl chr13:42,745,947...42,967,058

G

sorcin

affects expression

Vitamin K 3 affects the expression of SRI mRNA

NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077

G

SRSF protein kinase 1

affects expression

Vitamin K 3 affects the expression of SRPK1 mRNA

NCBI chr20:6,645,809...6,682,448
Ensembl chr20:6,645,809...6,682,134

G

serine/arginine repetitive matrix 2

affects expression

Vitamin K 3 affects the expression of SRRM2 mRNA

NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751

G

serine and arginine rich splicing factor 11

affects expression

Vitamin K 3 affects the expression of SRSF11 mRNA

NCBI chr 2:247,074,623...247,101,460
Ensembl chr 2:247,074,631...247,101,425

G

sulfiredoxin 1

increases expression

Vitamin K 3 results in increased expression of SRXN1 mRNA

PMID:23410634 PMID:25270620

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

somatostatin

decreases expression

Vitamin K 3 results in decreased expression of SST mRNA

NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173

G

ST14 transmembrane serine protease matriptase

affects expression

Vitamin K 3 affects the expression of ST14 mRNA

NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

affects expression

Vitamin K 3 affects the expression of ST3GAL6 mRNA

NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776

G

STAG3 cohesin complex component

increases expression

Vitamin K 3 results in increased expression of STAG3 mRNA

NCBI chr12:17,284,677...17,314,936
Ensembl chr12:17,284,794...17,314,935

G

serine/threonine kinase 36

increases expression

Vitamin K 3 results in increased expression of STK36 mRNA

NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422

G

serine/threonine kinase receptor associated protein

affects expression

Vitamin K 3 affects the expression of STRAP mRNA

NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828

G

sulfite oxidase

affects expression

Vitamin K 3 affects the expression of SUOX mRNA

NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038

G

sushi domain containing 1

affects expression

Vitamin K 3 affects the expression of SUSD1 mRNA

NCBI chr 5:74,157,653...74,281,171
Ensembl chr 5:74,157,773...74,276,291

G

sushi domain containing 6

affects expression

Vitamin K 3 affects the expression of SUSD6 mRNA

NCBI chr 6:100,437,834...100,531,621
Ensembl chr 6:100,437,642...100,531,606

G

spectrin repeat containing, nuclear envelope family member 3

affects expression

Vitamin K 3 affects the expression of SYNE3 mRNA

NCBI chr 6:123,872,895...123,964,773
Ensembl chr 6:123,873,174...123,953,409

G

transforming, acidic coiled-coil containing protein 1

affects expression

Vitamin K 3 affects the expression of TACC1 mRNA

NCBI chr16:66,812,232...66,895,736
Ensembl chr16:66,812,295...66,895,733

G

transforming, acidic coiled-coil containing protein 2

affects expression

Vitamin K 3 affects the expression of TACC2 mRNA

NCBI chr 1:185,139,223...185,327,881
Ensembl chr 1:185,116,111...185,327,881

G

TATA-box binding protein associated factor 15

affects expression

Vitamin K 3 affects the expression of TAF15 mRNA

NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949

G

TBC1 domain family member 9B

affects expression

Vitamin K 3 affects the expression of TBC1D9B mRNA

NCBI chr10:34,459,930...34,497,146
Ensembl chr10:34,459,953...34,497,145

G

TBL1X/Y related 1

affects expression

Vitamin K 3 affects the expression of TBL1XR1 mRNA

NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055

G

T-box transcription factor 2

affects expression

Vitamin K 3 affects the expression of TBX2 mRNA

NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529

G

transcription factor 7 like 2

decreases expression

Vitamin K 3 results in decreased expression of TCF7L2 protein

NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967

G

treacle ribosome biogenesis factor 1

affects expression

Vitamin K 3 affects the expression of TCOF1 mRNA

NCBI chr18:54,267,015...54,300,324
Ensembl chr18:54,267,026...54,300,324

G

TEA domain transcription factor 4

affects expression

Vitamin K 3 affects the expression of TEAD4 mRNA

NCBI chr 4:161,474,122...161,572,837
Ensembl chr 4:161,497,851...161,572,323

G

tectonin beta-propeller repeat containing 2

affects expression

Vitamin K 3 affects the expression of TECPR2 mRNA

NCBI chr 6:129,899,541...130,001,975
Ensembl chr 6:129,899,636...130,001,974

G

teneurin transmembrane protein 3

affects expression

Vitamin K 3 affects the expression of TENM3 mRNA

NCBI chr16:41,251,909...43,978,594
Ensembl chr16:41,252,182...43,978,594

G

terminal nucleotidyltransferase 2

affects expression

Vitamin K 3 affects the expression of TENT2 mRNA

NCBI chr 2:24,380,135...24,432,099
Ensembl chr 2:24,380,225...24,432,099

G

TEPSIN, adaptor related protein complex 4 accessory protein

affects expression

Vitamin K 3 affects the expression of TEPSIN mRNA

NCBI chr10:105,373,939...105,381,310
Ensembl chr10:105,373,941...105,382,266

G

testis associated actin remodelling kinase 1

affects expression

Vitamin K 3 affects the expression of TESK1 mRNA

NCBI chr 5:57,691,922...57,697,698
Ensembl chr 5:57,691,969...57,697,698

G

transcription factor AP-2 gamma

increases expression

Vitamin K 3 results in increased expression of TFAP2C mRNA

NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995

G

transcription factor binding to IGHM enhancer 3

affects expression

Vitamin K 3 affects the expression of TFE3 mRNA

NCBI chr X:14,729,547...14,742,830
Ensembl chr X:14,729,550...14,742,571

G

trefoil factor 1

affects expression

Vitamin K 3 affects the expression of TFF1 mRNA

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

trefoil factor 3

affects expression

Vitamin K 3 affects the expression of TFF3 mRNA

NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054

G

transferrin receptor

affects expression

Vitamin K 3 affects the expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor beta 1 induced transcript 1

affects expression

Vitamin K 3 affects the expression of TGFB1I1 mRNA

NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080

G

transforming growth factor, beta receptor 2

affects expression

Vitamin K 3 affects the expression of TGFBR2 mRNA

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

G

THAP domain containing 1

affects expression

Vitamin K 3 affects the expression of THAP1 mRNA

NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942

G

THAP domain containing 4

affects expression

Vitamin K 3 affects the expression of THAP4 mRNA

NCBI chr 9:94,242,581...94,282,312
Ensembl chr 9:94,242,581...94,282,306

G

thyroid hormone receptor alpha

affects expression

Vitamin K 3 affects the expression of THRA mRNA

NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936

G

TIR domain containing adaptor molecule 1

affects expression

Vitamin K 3 affects the expression of TICAM1 mRNA

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

G

timeless circadian regulator

affects expression

Vitamin K 3 affects the expression of TIMELESS mRNA

NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738

G

translocase of inner mitochondrial membrane 22

affects expression

Vitamin K 3 affects the expression of TIMM22 mRNA

NCBI chr10:61,253,459...61,261,217
Ensembl chr10:61,253,450...61,261,755

G

translocase of inner mitochondrial membrane 23

affects expression

Vitamin K 3 affects the expression of TIMM23 mRNA

NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379

G

translocase of inner mitochondrial membrane 9

affects expression

Vitamin K 3 affects the expression of TIMM9 mRNA

NCBI chr 6:89,610,094...89,622,924
Ensembl chr 6:89,610,094...89,622,924

G

TIMP metallopeptidase inhibitor 2

affects expression

Vitamin K 3 affects the expression of TIMP2 mRNA

NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611

G

TCDD-inducible poly(ADP-ribose) polymerase

affects expression

Vitamin K 3 affects the expression of TIPARP mRNA

PMID:20044591 PMID:20829426

NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327

G

tight junction protein 1

increases expression

Vitamin K 3 results in increased expression of TJP1 protein

NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432

G

tight junction protein 2

affects expression

Vitamin K 3 affects the expression of TJP2 mRNA

NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295

G

thymidine kinase 1

affects expression
decreases expression

Vitamin K 3 affects the expression of TK1 mRNA
Vitamin K 3 results in decreased expression of TK1 mRNA

PMID:12414654 PMID:20044591

NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920

G

tousled-like kinase 1

affects expression

Vitamin K 3 affects the expression of TLK1 mRNA

NCBI chr 3:55,520,559...55,627,580
Ensembl chr 3:55,503,358...55,691,968

G

TM2 domain containing 3

affects expression

Vitamin K 3 affects the expression of TM2D3 mRNA

NCBI chr 1:119,267,194...119,277,094
Ensembl chr 1:119,264,576...119,277,099

G

transmembrane 7 superfamily member 2

affects expression

Vitamin K 3 affects the expression of TM7SF2 mRNA

NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270

G

transmembrane p24 trafficking protein 10

affects expression

Vitamin K 3 affects the expression of TMED10 mRNA

NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753

G

transmembrane protein 125

affects expression

Vitamin K 3 affects the expression of TMEM125 mRNA

NCBI chr 5:132,063,162...132,064,566
Ensembl chr 5:132,059,554...132,079,297
Ensembl chr 5:132,059,554...132,079,297

G

transmembrane protein 177

affects expression

Vitamin K 3 affects the expression of TMEM177 mRNA

NCBI chr13:31,023,893...31,027,368
Ensembl chr13:31,023,455...31,027,378

G

transmembrane protein 18

affects expression

Vitamin K 3 affects the expression of TMEM18 mRNA

NCBI chr 6:47,206,845...47,214,294
Ensembl chr 6:47,206,845...47,214,294

G

transmembrane protein 237

affects expression

Vitamin K 3 affects the expression of TMEM237 mRNA

NCBI chr 9:60,533,348...60,569,253
Ensembl chr 9:60,535,233...60,572,567

G

transmembrane protein 245

affects expression

Vitamin K 3 affects the expression of TMEM245 mRNA

NCBI chr 5:71,570,952...71,647,915
Ensembl chr 5:71,514,858...71,647,763

G

transmembrane protein 37

affects expression

Vitamin K 3 affects the expression of TMEM37 mRNA

NCBI chr13:31,184,322...31,191,477
Ensembl chr13:31,171,355...31,191,077

G

transmembrane protein 42

affects expression

Vitamin K 3 affects the expression of TMEM42 mRNA

NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276

G

transmembrane protein 45b

affects expression

Vitamin K 3 affects the expression of TMEM45B mRNA

NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453

G

transmembrane protein 79

affects expression

Vitamin K 3 affects the expression of TMEM79 mRNA

NCBI chr 2:173,798,267...173,803,151
Ensembl chr 2:173,798,267...173,803,046

G

thymopoietin

decreases expression

Vitamin K 3 results in decreased expression of TMPO mRNA

NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727

G

transmembrane serine protease 13

affects expression

Vitamin K 3 affects the expression of TMPRSS13 mRNA

NCBI chr 8:45,625,759...45,653,943
Ensembl chr 8:45,625,626...45,653,938

G

transmembrane O-mannosyltransferase targeting cadherins 4

affects expression

Vitamin K 3 affects the expression of TMTC4 mRNA

NCBI chr15:100,000,157...100,056,573
Ensembl chr15:100,000,152...100,056,543

G

tumor necrosis factor

multiple interactions
increases secretion
increases expression

Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of TNF mRNA]; Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of TNF protein]
Vitamin K 3 inhibits the reaction [Lipopolysaccharides affects the localization of TNF protein]; Vitamin K 3 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
[Asbestos, Amosite co-treated with TNF protein] results in increased susceptibility to Vitamin K 3; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3; Vitamin K 3 inhibits the reaction [TNF protein affects the localization of RELA protein]; Vitamin K 3 promotes the reaction [[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate]

PMID:8817062 PMID:19265712 PMID:19362101 PMID:20030669

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 11B

increases expression

Vitamin K 3 results in increased expression of TNFRSF11B mRNA

NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538

G

TNF receptor superfamily member 12A

affects expression

Vitamin K 3 affects the expression of TNFRSF12A mRNA

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

TNF receptor superfamily member 19

affects expression

Vitamin K 3 affects the expression of TNFRSF19 mRNA

NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795

G

TNF superfamily member 11

decreases expression

Vitamin K 3 results in decreased expression of TNFSF11 mRNA

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

G

tenascin XB

affects expression

Vitamin K 3 affects the expression of TNXB mRNA

G

target of myb1 membrane trafficking protein

increases expression

Vitamin K 3 results in increased expression of TOM1 mRNA

NCBI chr19:13,405,482...13,440,384
Ensembl chr19:13,405,501...13,440,384

G

translocase of outer mitochondrial membrane 22

affects expression

Vitamin K 3 affects the expression of TOMM22 mRNA

NCBI chr 7:111,223,508...111,228,671
Ensembl chr 7:111,216,571...111,246,799

G

DNA topoisomerase I

affects expression

Vitamin K 3 affects the expression of TOP1 mRNA

NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623

G

DNA topoisomerase II alpha

affects expression

Vitamin K 3 affects the expression of TOP2A mRNA

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

DNA topoisomerase II beta

affects expression

Vitamin K 3 affects the expression of TOP2B mRNA

NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085

G

tumor protein p53

multiple interactions
affects activity
increases expression

[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein; EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of TP53 protein]; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein]
Vitamin K 3 affects the activity of TP53 protein

PMID:19082730 PMID:21533478 PMID:25005833 PMID:35435491

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

TPX2, microtubule nucleation factor

affects expression

Vitamin K 3 affects the expression of TPX2 mRNA

NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468

G

TNFRSF1A-associated via death domain

affects expression

Vitamin K 3 affects the expression of TRADD mRNA

NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638

G

Traf3 interacting protein 2

affects expression

Vitamin K 3 affects the expression of TRAF3IP2 mRNA

NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667

G

triggering receptor expressed on myeloid cells 2

affects expression

Vitamin K 3 affects the expression of TREM2 mRNA

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

G

tribbles pseudokinase 3

increases expression

Vitamin K 3 results in increased expression of TRIB3 mRNA

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

tripartite motif-containing 14

affects expression

Vitamin K 3 affects the expression of TRIM14 mRNA

NCBI chr 5:60,800,568...60,824,858
Ensembl chr 5:60,800,032...60,824,858

G

tripartite motif-containing 2

affects expression

Vitamin K 3 affects the expression of TRIM2 mRNA

NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927

G

tripartite motif-containing 26

affects expression

Vitamin K 3 affects the expression of TRIM26 mRNA

NCBI chr20:1,708,297...1,731,176
Ensembl chr20:1,709,788...1,731,120

G

tRNA methyltransferase 61A

affects expression

Vitamin K 3 affects the expression of TRMT61A mRNA

NCBI chr 6:130,737,230...130,743,251
Ensembl chr 6:130,737,219...130,743,243

G

transient receptor potential cation channel, subfamily A, member 1

increases activity

Vitamin K 3 results in increased activity of TRPA1 protein

NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570

G

transformation/transcription domain-associated protein

affects expression

Vitamin K 3 affects the expression of TRRAP mRNA

NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674

G

TSC22 domain family, member 2

affects expression

Vitamin K 3 affects the expression of TSC22D2 mRNA

NCBI chr 2:142,646,778...142,697,977
Ensembl chr 2:142,644,744...142,693,606

G

tetraspanin 3

affects expression

Vitamin K 3 affects the expression of TSPAN3 mRNA

NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880

G

tetraspanin 5

affects expression

Vitamin K 3 affects the expression of TSPAN5 mRNA

NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664

G

tetraspanin 6

affects expression

Vitamin K 3 affects the expression of TSPAN6 mRNA

NCBI chr X:97,092,394...97,099,659
Ensembl chr X:97,092,388...97,099,309

G

TSPY-like 2

affects expression

Vitamin K 3 affects the expression of TSPYL2 mRNA

NCBI chr X:21,439,478...21,445,208
Ensembl chr X:21,439,478...21,445,089

G

thiosulfate sulfurtransferase

affects expression

Vitamin K 3 affects the expression of TST mRNA

NCBI chr 7:109,948,061...109,955,378
Ensembl chr 7:109,948,062...109,957,216

G

tetratricopeptide repeat domain 3

affects expression

Vitamin K 3 affects the expression of TTC3 mRNA

NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975

G

tubulin, alpha 1A

decreases expression

Vitamin K 3 results in decreased expression of TUBA1A mRNA

NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186

G

TUB like protein 3

affects expression

Vitamin K 3 affects the expression of TULP3 mRNA

NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149

G

TUB like protein 4

affects expression

Vitamin K 3 affects the expression of TULP4 mRNA

NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688

G

twinfilin actin-binding protein 2

decreases expression

Vitamin K 3 results in decreased expression of TWF2 mRNA

NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298

G

thioredoxin interacting protein

affects expression

Vitamin K 3 affects the expression of TXNIP mRNA

NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886

G

thioredoxin reductase 1

increases expression

Vitamin K 3 results in increased expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

tyrosine kinase 2

affects expression

Vitamin K 3 affects the expression of TYK2 mRNA

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

G

thymidylate synthetase

affects expression

Vitamin K 3 affects the expression of TYMS mRNA

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

ubiquitin B

affects expression

Vitamin K 3 affects the expression of UBB mRNA

NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333

G

ubiquitin C

affects expression

Vitamin K 3 affects the expression of UBC mRNA

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

G

ubiquitin-conjugating enzyme E2C

decreases expression

Vitamin K 3 results in decreased expression of UBE2C mRNA

NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339

G

ubiquitin protein ligase E3 component n-recognin 4

affects expression

Vitamin K 3 affects the expression of UBR4 mRNA

NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784

G

uncoupling protein 2

affects expression

Vitamin K 3 affects the expression of UCP2 mRNA

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

UDP-glucose ceramide glucosyltransferase

affects expression

Vitamin K 3 affects the expression of UGCG mRNA

NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393

G

UDP glucuronosyltransferase family 1 member A6

multiple interactions
increases expression
increases activity

Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of UGT1A6 promoter]
Vitamin K 3 results in increased expression of UGT1A6 mRNA

PMID:15336321 PMID:22846377

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

ubiquitin-like with PHD and ring finger domains 1

affects expression

Vitamin K 3 affects the expression of UHRF1 mRNA

NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631

G

uracil-DNA glycosylase

decreases expression

Vitamin K 3 results in decreased expression of UNG mRNA

NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206

G

UPF3A, regulator of nonsense mediated mRNA decay

affects expression

Vitamin K 3 affects the expression of UPF3A mRNA

NCBI chr16:75,757,442...75,768,478
Ensembl chr16:75,757,441...75,769,345

G

uridine phosphorylase 1

affects expression
decreases expression

Vitamin K 3 affects the expression of UPP1 mRNA
Vitamin K 3 results in decreased expression of UPP1 mRNA

PMID:20044591 PMID:25270620

NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462

G

USH1 protein network component harmonin

affects expression

Vitamin K 3 affects the expression of USH1C mRNA

NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671

G

USH1 protein network component harmonin binding protein 1

increases expression

Vitamin K 3 results in increased expression of USHBP1 mRNA

NCBI chr16:18,057,321...18,067,933
Ensembl chr16:18,057,326...18,067,877

G

ubiquitin specific peptidase 10

affects expression

Vitamin K 3 affects the expression of USP10 mRNA

NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897

G

ubiquitin specific peptidase 7

affects expression

Vitamin K 3 affects the expression of USP7 mRNA

NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355

G

ubiquitin specific peptidase 9, X-linked

affects expression

Vitamin K 3 affects the expression of USP9X mRNA

NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711

G

valyl-tRNA synthetase 2, mitochondrial

affects expression

Vitamin K 3 affects the expression of VARS2 mRNA

NCBI chr20:3,077,132...3,087,994
Ensembl chr20:3,077,132...3,087,994

G

vasorin

affects expression

Vitamin K 3 affects the expression of VASN mRNA

NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357

G

voltage-dependent anion channel 1

affects expression

Vitamin K 3 affects the expression of VDAC1 mRNA

NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640

G

vascular endothelial zinc finger 1

affects expression

Vitamin K 3 affects the expression of VEZF1 mRNA

NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111

G

vestigial-like family member 4

affects expression

Vitamin K 3 affects the expression of VGLL4 mRNA

NCBI chr 4:147,925,630...148,038,519
Ensembl chr 4:147,927,034...148,038,471

G

von Hippel-Lindau tumor suppressor

multiple interactions

[[Vitamin K 3 results in increased phosphorylation of JAK3 protein] which results in increased phosphorylation of and affects the localization of ELAVL1 protein] inhibits the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]; Vitamin K 3 inhibits the reaction [sodium arsenite promotes the reaction [ELAVL1 protein binds to and results in decreased degradation of VHL mRNA]]; Vitamin K 3 inhibits the reaction [sodium arsenite results in decreased degradation of VHL mRNA]

NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377

G

vimentin

decreases expression

Vitamin K 3 results in decreased expression of VIM protein

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

vitamin K epoxide reductase complex, subunit 1-like 1

affects expression

Vitamin K 3 affects the expression of VKORC1L1 mRNA

NCBI chr12:26,717,959...26,768,193
Ensembl chr12:26,623,976...26,768,225

G

VPS28 subunit of ESCRT-I

affects expression

Vitamin K 3 affects the expression of VPS28 mRNA

NCBI chr 7:108,341,989...108,345,837
Ensembl chr 7:108,341,989...108,345,837

G

VPS39 subunit of HOPS complex

decreases expression

Vitamin K 3 results in decreased expression of VPS39 mRNA

NCBI chr 3:107,266,846...107,304,884
Ensembl chr 3:107,267,310...107,304,975

G

visinin-like 1

affects expression

Vitamin K 3 affects the expression of VSNL1 mRNA

NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479

G

vitronectin

affects expression

Vitamin K 3 affects the expression of VTN mRNA

NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810

G

von Willebrand factor A domain containing 1

affects expression

Vitamin K 3 affects the expression of VWA1 mRNA

NCBI chr 5:166,377,451...166,382,784
Ensembl chr 5:166,377,455...166,382,637

G

WW domain binding protein 1

affects expression

Vitamin K 3 affects the expression of WBP1 mRNA

NCBI chr 4:115,625,168...115,627,567
Ensembl chr 4:115,625,168...115,627,624

G

WD repeat domain 3

affects expression

Vitamin K 3 affects the expression of WDR3 mRNA

NCBI chr 2:187,505,816...187,528,432
Ensembl chr 2:187,505,816...187,528,432

G

WD repeat domain 59

affects expression

Vitamin K 3 affects the expression of WDR59 mRNA

NCBI chr19:39,416,432...39,483,773
Ensembl chr19:39,416,429...39,483,698

G

WD repeat domain 81

affects expression

Vitamin K 3 affects the expression of WDR81 mRNA

NCBI chr10:60,281,969...60,295,374
Ensembl chr10:60,281,972...60,295,296

G

WD repeat domain, phosphoinositide interacting 1

affects expression

Vitamin K 3 affects the expression of WIPI1 mRNA

NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846

G

WW and C2 domain containing 1

affects expression

Vitamin K 3 affects the expression of KIBRA mRNA

NCBI chr10:20,300,735...20,454,393
Ensembl chr10:20,300,833...20,454,497

G

WW domain-containing oxidoreductase

affects expression

Vitamin K 3 affects the expression of WWOX mRNA

NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391

G

WW domain containing transcription regulator 1

increases expression

Vitamin K 3 results in increased expression of WWTR1 mRNA

NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968

G

X-box binding protein 1

affects expression

Vitamin K 3 affects the expression of XBP1 mRNA

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

X inactive specific transcript

affects expression

Vitamin K 3 affects the expression of XIST mRNA

NCBI chr X:68,474,987...68,492,500

G

exportin 1

affects expression

Vitamin K 3 affects the expression of XPO1 mRNA

NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498

G

exportin 5

affects expression

Vitamin K 3 affects the expression of XPO5 mRNA

NCBI chr 9:14,740,182...14,778,171
Ensembl chr 9:14,740,182...14,778,171

G

YEATS domain containing 4

affects expression

Vitamin K 3 affects the expression of YEATS4 mRNA

NCBI chr 7:52,858,313...52,865,454
Ensembl chr 7:52,858,305...52,865,635

G

YKT6 v-SNARE homolog

affects expression

Vitamin K 3 affects the expression of YKT6 mRNA

NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385

G

yrdC N(6)-threonylcarbamoyltransferase domain containing

affects expression

Vitamin K 3 affects the expression of YRDC mRNA

NCBI chr 5:137,110,244...137,115,127
Ensembl chr 5:137,110,279...137,115,120

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

affects expression

Vitamin K 3 affects the expression of YWHAB mRNA

NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105

G

zinc finger CCCH type containing 12A

affects expression

Vitamin K 3 affects the expression of ZC3H12A mRNA

NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351

G

zinc finger CCHC-type containing 14

affects expression

Vitamin K 3 affects the expression of ZCCHC14 mRNA

NCBI chr19:49,674,185...49,718,004
Ensembl chr19:49,674,195...49,718,029

G

zinc finger E-box binding homeobox 1

decreases expression

Vitamin K 3 results in decreased expression of ZEB1 protein

NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214

G

zinc finger AN1-type containing 2A

affects expression

Vitamin K 3 affects the expression of ZFAND2A mRNA

NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677

G

zinc finger homeobox 3

affects expression

Vitamin K 3 affects the expression of ZFHX3 mRNA

NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771

G

zinc finger protein 133

affects expression

Vitamin K 3 affects the expression of ZNF133 mRNA

NCBI chr 3:131,829,404...131,847,552
Ensembl chr 3:131,829,404...131,847,550

G

zinc finger protein 217

affects expression

Vitamin K 3 affects the expression of ZNF217 mRNA

NCBI chr 3:158,890,464...158,931,148
Ensembl chr 3:158,892,265...158,913,040

G

zinc finger protein 36, C3H type-like 1

affects expression

Vitamin K 3 affects the expression of ZFP36L1 mRNA

NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748

G

zinc finger protein 36, C3H type-like 2

affects expression

Vitamin K 3 affects the expression of ZFP36L2 mRNA

NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064

G

zinc finger protein 395

affects expression

Vitamin K 3 affects the expression of ZNF395 mRNA

NCBI chr15:39,581,603...39,621,911
Ensembl chr15:39,608,080...39,619,950

G

zinc finger protein 462

affects expression

Vitamin K 3 affects the expression of ZNF462 mRNA

NCBI chr 5:69,670,085...69,810,729
Ensembl chr 5:69,670,328...69,810,327

G

zinc finger protein 524

affects expression

Vitamin K 3 affects the expression of ZNF524 mRNA

NCBI chr 1:68,824,803...68,828,363
Ensembl chr 1:68,824,803...68,828,594

G

zinc finger protein 593

affects expression

Vitamin K 3 affects the expression of ZNF593 mRNA

NCBI chr 5:146,462,670...146,464,998
Ensembl chr 5:146,462,670...146,465,198

G

zinc finger protein 62

affects expression

Vitamin K 3 affects the expression of ZFP62 mRNA

NCBI chr10:33,522,618...33,539,446
Ensembl chr10:33,500,323...33,542,013

G

zinc finger protein 706

affects expression

Vitamin K 3 affects the expression of ZNF706 mRNA

NCBI chr 7:68,167,496...68,174,121
Ensembl chr 7:68,166,323...68,174,148

G

zinc finger protein 707

affects expression

Vitamin K 3 affects the expression of ZNF707 mRNA

NCBI chr 7:107,679,597...107,686,556
Ensembl chr 7:107,650,217...107,703,459

G

zinc finger protein 830

affects expression

Vitamin K 3 affects the expression of ZNF830 mRNA

NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523

G

zinc finger TRAF type containing 1

affects expression

Vitamin K 3 affects the expression of ZFTRAF1 mRNA

NCBI chr 7:108,363,989...108,377,428
Ensembl chr 7:108,364,381...108,380,021

G

zinc finger FYVE-type containing 21

affects expression

Vitamin K 3 affects the expression of ZFYVE21 mRNA

NCBI chr 6:130,873,979...130,894,618
Ensembl chr 6:130,873,912...130,894,411

G

zinc finger, MIZ-type containing 1

affects expression

Vitamin K 3 affects the expression of ZMIZ1 mRNA

NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597

G

zinc ribbon domain containing 2

affects expression

Vitamin K 3 affects the expression of ZNRD2 mRNA

NCBI chr 1:203,017,682...203,019,465
Ensembl chr 1:203,017,682...203,019,465

G

zinc and ring finger 1

affects expression

Vitamin K 3 affects the expression of ZNRF1 mRNA

NCBI chr19:39,496,414...39,581,600
Ensembl chr19:39,496,527...39,580,969

G

zinc finger, SWIM-type containing 3

affects expression

Vitamin K 3 affects the expression of ZSWIM3 mRNA

NCBI chr 3:153,542,741...153,558,022
Ensembl chr 3:153,542,743...153,558,018

G

ZW10 interacting kinetochore protein

affects expression

Vitamin K 3 affects the expression of ZWINT mRNA

NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957

G

zyxin

affects expression

Vitamin K 3 affects the expression of ZYX mRNA

NCBI chr 4:71,236,767...71,246,553
Ensembl chr 4:71,237,451...71,246,553

menaquinone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

multiple interactions

Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

alkaline phosphatase, biomineralization associated

increases expression
multiple interactions

Vitamin K 2 results in increased expression of ALPL protein
PTH protein promotes the reaction [Vitamin K 2 results in increased expression of ALPL protein]; Vitamin K 2 affects the reaction [PTH protein results in increased expression of ALPL protein]

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

Axl receptor tyrosine kinase

multiple interactions

Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased expression of AXL protein]

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

BCL2, apoptosis regulator

multiple interactions

Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased expression of BCL2 protein]

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

bone gamma-carboxyglutamate protein

multiple interactions
increases secretion
decreases expression

Vitamin K 2 inhibits the reaction [IL1B protein results in decreased expression of BGLAP protein modified form]
PTH protein promotes the reaction [Vitamin K 2 results in increased carboxylation of BGLAP protein]; PTH protein promotes the reaction [Vitamin K 2 results in increased secretion of BGLAP protein modified form]; Vitamin K 2 promotes the reaction [PTH protein results in increased carboxylation of BGLAP protein]; Vitamin K 2 promotes the reaction [PTH protein results in increased secretion of BGLAP protein modified form]; Vitamin K 2 results in increased carboxylation of and results in decreased secretion of BGLAP protein
Vitamin K 2 results in decreased expression of BGLAP mRNA

PMID:19675304 PMID:20460758 PMID:30639440

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

baculoviral IAP repeat-containing 5

decreases expression

Vitamin K 2 results in decreased expression of BIRC5 protein

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

bone morphogenetic protein 2

multiple interactions

Vitamin K 2 affects the reaction [PTH protein results in increased expression of BMP2 protein]

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

caspase 3

multiple interactions
increases cleavage

[Vitamin K 2 co-treated with arsenic trioxide] results in increased expression of CASP3; Acetylcysteine inhibits the reaction [[Vitamin K 2 co-treated with arsenic trioxide] results in increased expression of CASP3]
Vitamin K 2 results in increased cleavage of CASP3 protein

PMID:24273890 PMID:29432837

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 7

increases cleavage

Vitamin K 2 results in increased cleavage of CASP7 protein

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

cyclin-dependent kinase 4

decreases expression

Vitamin K 2 results in decreased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

increases expression

Vitamin K 2 results in increased expression of CDKN1A protein

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 2A

increases expression

Vitamin K 2 results in increased expression of CDKN2A mRNA

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

collagen type I alpha 1 chain

decreases expression

Vitamin K 2 results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

coagulation factor X

multiple interactions

[Phenobarbital co-treated with Vitamin K 2] results in increased activity of F10 protein

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

G

coagulation factor VII

multiple interactions

[Phenobarbital co-treated with Vitamin K 2] results in increased activity of F7 protein

NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610

G

growth arrest specific 6

multiple interactions

Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased expression of GAS6 protein]

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

G

H2A.X variant histone

increases phosphorylation

Vitamin K 2 results in increased phosphorylation of H2AX protein

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

heat shock protein family A (Hsp70) member 5

decreases expression

Vitamin K 2 results in decreased expression of HSPA5 protein

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

interleukin 1 beta

multiple interactions
decreases response to substance

Vitamin K 2 inhibits the reaction [IL1B protein results in decreased expression of BGLAP protein modified form]; Warfarin inhibits the reaction [Vitamin K 2 results in decreased susceptibility to IL1B protein]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
increases activity

PROX1 protein inhibits the reaction [Vitamin K 2 results in increased activity of NR1I2 protein]

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

poly (ADP-ribose) polymerase 1

increases cleavage

Vitamin K 2 results in increased cleavage of PARP1 protein

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

prospero homeobox 1

multiple interactions

PROX1 protein inhibits the reaction [Vitamin K 2 results in increased activity of NR1I2 protein]

NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183

G

parathyroid hormone

multiple interactions

PTH protein promotes the reaction [Vitamin K 2 results in increased carboxylation of BGLAP protein]; PTH protein promotes the reaction [Vitamin K 2 results in increased expression of ALPL protein]; PTH protein promotes the reaction [Vitamin K 2 results in increased expression of RUNX2 protein]; PTH protein promotes the reaction [Vitamin K 2 results in increased expression of SP7 protein]; PTH protein promotes the reaction [Vitamin K 2 results in increased secretion of BGLAP protein modified form]; Vitamin K 2 affects the reaction [PTH protein results in increased expression of ALPL protein]; Vitamin K 2 affects the reaction [PTH protein results in increased expression of BMP2 protein]; Vitamin K 2 affects the reaction [PTH protein results in increased expression of RUNX2 protein]; Vitamin K 2 affects the reaction [PTH protein results in increased expression of SP7 protein]; Vitamin K 2 promotes the reaction [PTH protein results in increased carboxylation of BGLAP protein]; Vitamin K 2 promotes the reaction [PTH protein results in increased secretion of BGLAP protein modified form]

NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530

G

RB transcriptional corepressor 1

increases expression

Vitamin K 2 results in increased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RUNX family transcription factor 2

increases expression
multiple interactions

Vitamin K 2 results in increased expression of RUNX2 protein
PTH protein promotes the reaction [Vitamin K 2 results in increased expression of RUNX2 protein]; Vitamin K 2 affects the reaction [PTH protein results in increased expression of RUNX2 protein]

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

retinoid X receptor alpha

multiple interactions
decreases phosphorylation

[Vitamin K 2 co-treated with 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid] results in decreased phosphorylation of RXRA protein
Vitamin K 2 results in decreased phosphorylation of RXRA protein

NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712

G

Sp7 transcription factor

increases expression
multiple interactions

Vitamin K 2 results in increased expression of SP7 protein
PTH protein promotes the reaction [Vitamin K 2 results in increased expression of SP7 protein]; Vitamin K 2 affects the reaction [PTH protein results in increased expression of SP7 protein]

NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847

G

TNF superfamily member 11

decreases expression

Vitamin K 2 results in decreased expression of TNFSF11 mRNA

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

menaquinone-4

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alkaline phosphatase, biomineralization associated

increases activity

menatetrenone results in increased activity of ALPL protein

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

bone gamma-carboxyglutamate protein

increases expression
multiple interactions
increases carboxylation

menatetrenone results in increased expression of BGLAP mRNA
Warfarin inhibits the reaction [menatetrenone results in increased carboxylation of BGLAP protein]

PMID:11113387 PMID:31173816

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

bone morphogenetic protein 2

multiple interactions
increases expression
increases response to substance

Coumestrol inhibits the reaction [menatetrenone promotes the reaction [Phosphates results in increased expression of BMP2 mRNA]]; Coumestrol inhibits the reaction [menatetrenone results in increased expression of BMP2 mRNA]; Coumestrol inhibits the reaction [menatetrenone results in increased susceptibility to BMP2 protein]; Coumestrol inhibits the reaction [Phosphates promotes the reaction [menatetrenone results in increased expression of BMP2 mRNA]]; Ketoconazole inhibits the reaction [menatetrenone promotes the reaction [Phosphates results in increased expression of BMP2 mRNA]]; Ketoconazole inhibits the reaction [Phosphates promotes the reaction [menatetrenone results in increased expression of BMP2 mRNA]]; menatetrenone promotes the reaction [Phosphates results in increased expression of BMP2 mRNA]; Phosphates promotes the reaction [menatetrenone results in increased expression of BMP2 mRNA]

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

nuclear receptor subfamily 1, group I, member 2

increases activity

menatetrenone results in increased activity of NR1I2 protein

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

TNF receptor superfamily member 11B

increases expression

menatetrenone results in increased expression of TNFRSF11B mRNA

NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538

G

TNF superfamily member 11

multiple interactions

menatetrenone inhibits the reaction [Calcitriol results in increased expression of TNFSF11 mRNA]

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

G

UbiA prenyltransferase domain containing 1

multiple interactions

[UBIAD1 protein results in increased metabolism of Vitamin K metabolite] which results in increased chemical synthesis of menatetrenone

NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271

menaquinone-7

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

bone gamma-carboxyglutamate protein

multiple interactions
increases carboxylation

Warfarin inhibits the reaction [menaquinone 7 results in increased carboxylation of BGLAP protein]

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

TNF receptor superfamily member 11B

increases expression

menaquinone 7 results in increased expression of TNFRSF11B mRNA

NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538

phylloquinone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

multiple interactions

[Warfarin co-treated with Vitamin K 1] results in decreased phosphorylation of AKT1 protein; Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

Axl receptor tyrosine kinase

multiple interactions

[Warfarin co-treated with Vitamin K 1] results in decreased expression of AXL protein; Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased expression of AXL protein]

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

BCL2, apoptosis regulator

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in decreased expression of BCL2 protein
[Warfarin co-treated with Vitamin K 1] results in decreased expression of BCL2 protein; Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased expression of BCL2 protein]

PMID:20301194 PMID:27212383

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

bone gamma-carboxyglutamate protein

increases carboxylation
multiple interactions

Vitamin K 1 results in increased carboxylation of BGLAP protein
Warfarin inhibits the reaction [Vitamin K 1 results in increased carboxylation of BGLAP protein]

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

BH3 interacting domain death agonist

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in increased cleavage of BID protein

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

bone morphogenetic protein 2

multiple interactions

[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 mRNA; [Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 protein; Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 mRNA]; Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 protein]

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

caspase 3

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in increased cleavage of CASP3 protein
[Warfarin co-treated with Vitamin K 1] results in increased cleavage of CASP3 protein

PMID:20301194 PMID:23990204

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in increased cleavage of CASP8 protein

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

C-C motif chemokine ligand 2

multiple interactions

Vitamin K 1 affects the reaction [Ethylene Glycol affects the expression of CCL2 mRNA]

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

coagulation factor II, thrombin

increases expression

Vitamin K 1 deficiency results in increased expression of F2 protein modified form

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

coagulation factor IX

multiple interactions

[VKORC1 protein results in increased reduction of Vitamin K 1] which results in increased carboxylation of and results in increased activity of F9 protein; [VKORC1L1 protein results in increased reduction of Vitamin K 1] which results in increased carboxylation of and results in increased activity of F9 protein

NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835

G

Fas ligand

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in increased expression of FASLG protein; pyrazolanthrone inhibits the reaction [[sorafenib co-treated with Vitamin K 1] results in increased expression of FASLG protein]

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

Vitamin K 1 results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

growth arrest specific 6

multiple interactions

[Warfarin co-treated with Vitamin K 1] results in decreased expression of GAS6 protein; Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased expression of GAS6 protein]

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

G

glutathione S-transferase pi 1

multiple interactions

Vitamin K 1 inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

interleukin 6

multiple interactions

Vitamin K 1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[sorafenib co-treated with Vitamin K 1] results in increased phosphorylation of JUN protein]

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

mitogen activated protein kinase 1

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in decreased phosphorylation of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

[sorafenib co-treated with Vitamin K 1] results in decreased phosphorylation of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

matrix Gla protein

multiple interactions
increases expression

[Vitamin K 1 co-treated with Ethylene Glycol] results in increased expression of MGP protein; Vitamin K 1 results in increased expression of and results in increased secretion of MGP protein modified form; Warfarin inhibits the reaction [Vitamin K 1 results in increased expression of and results in increased secretion of MGP protein modified form]
Vitamin K 1 results in increased expression of MGP protein
[[Warfarin co-treated with Vitamin K 1] results in decreased carboxylation of MGP protein] which results in decreased activity of MGP protein; [Warfarin co-treated with Vitamin K 1] results in decreased activity of MGP protein; [Warfarin co-treated with Vitamin K 1] results in decreased carboxylation of MGP protein; [Warfarin co-treated with Vitamin K 1] results in decreased expression of MGP mRNA

PMID:21705322 PMID:23990204 PMID:31639794

NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667

G

RUNX family transcription factor 2

multiple interactions

[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA; [Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein; Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA]; Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein]

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

secreted phosphoprotein 1

multiple interactions

[Warfarin co-treated with Vitamin K 1] results in increased expression of SPP1 mRNA

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

transgelin

multiple interactions

[Warfarin co-treated with Vitamin K 1] results in decreased expression of TAGLN mRNA

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

vitamin K epoxide reductase complex, subunit 1

multiple interactions
increases reduction

4-hydroxycoumarin inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; [VKORC1 protein results in increased reduction of Vitamin K 1] which results in increased carboxylation of and results in increased activity of F9 protein; Acenocoumarol inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; bromadiolone inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; bromfenacoum inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; coumachlor inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; coumatetralyl inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; Dicumarol inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; ferulenol inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; fluindione inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; Phenindione inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; Phenprocoumon inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; Warfarin inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]

NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008

G

vitamin K epoxide reductase complex, subunit 1-like 1

multiple interactions
increases reduction

4-hydroxycoumarin inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; [VKORC1L1 protein results in increased reduction of Vitamin K 1] which results in increased carboxylation of and results in increased activity of F9 protein; Acenocoumarol inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; bromadiolone inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; bromfenacoum inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; coumachlor inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; coumatetralyl inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; Dicumarol inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; ferulenol inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; fluindione inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; Phenindione inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; Phenprocoumon inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]; Warfarin inhibits the reaction [VKORC1L1 protein results in increased reduction of Vitamin K 1]

NCBI chr12:26,717,959...26,768,193
Ensembl chr12:26,623,976...26,768,225

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19890
role	19839
biological role	19858
biochemical role	19566
vitamin (role)	14025
fat-soluble vitamin (role)	11261
vitamin K	1259
16-oxonapyradiomycin A2	0
Dimethylmenaquinone DMMK-8	0
Dimethylmenaquinone DMMK-8(VIII-H2)	0
Hexahydromenaquinone MK-9(II,III,IX-H6)	0
Hexahydromenaquinone MK-9(II,III,VIII-H6	0
II,III-Tetrahydro-omega-(2,6,6-trimethylcyclohex-2-enylmethyl)menaquinone-6	0
MK-8	0
Menaquinone MK-8(VIII-H2)	0
Menaquinone-10 (II-, III-H4)	0
Merochlorin D	0
Merochlorin E	0
Merochlorin F	0
Methylmenaquinone MMK-8	0
Methylmenaquinone MMK-8(VIII-H2)	0
Napyradiomycin A3	0
Octahydromenaquinone MK-9(II,III,VIII,IX)	0
SF2415B1	0
Tetrahydrom	0
delta7′′,8′′-6′′-hydroxynaphthomevalin	0
demethylmenaquinone-12	0
menadione +	1218
menaquinone +	30
phylloquinone	25
Path 2
Term	Annotations
CHEBI ontology	19890
subatomic particle	19867
composite particle	19888
hadron	19888
baryon	19888
nucleon	19867
atomic nucleus	19888
atom	19888
main group element atom	19806
p-block element atom	19806
carbon group element atom	19746
carbon atom	19743
organic molecular entity	19743
heteroorganic entity	19502
organochalcogen compound	19264
organooxygen compound	19180
carbonyl compound	18920
ketone	17269
cyclic ketone	15901
quinone	9905
naphthoquinone	1475
1,4-naphthoquinones	1463
vitamin K	1259
16-oxonapyradiomycin A2	0
Dimethylmenaquinone DMMK-8	0
Dimethylmenaquinone DMMK-8(VIII-H2)	0
Hexahydromenaquinone MK-9(II,III,IX-H6)	0
Hexahydromenaquinone MK-9(II,III,VIII-H6	0
II,III-Tetrahydro-omega-(2,6,6-trimethylcyclohex-2-enylmethyl)menaquinone-6	0
MK-8	0
Menaquinone MK-8(VIII-H2)	0
Menaquinone-10 (II-, III-H4)	0
Merochlorin D	0
Merochlorin E	0
Merochlorin F	0
Methylmenaquinone MMK-8	0
Methylmenaquinone MMK-8(VIII-H2)	0
Napyradiomycin A3	0
Octahydromenaquinone MK-9(II,III,VIII,IX)	0
SF2415B1	0
Tetrahydrom	0
delta7′′,8′′-6′′-hydroxynaphthomevalin	0
demethylmenaquinone-12	0
menadione +	1218
menaquinone +	30
phylloquinone	25

paths to the root