Gene: Mccc1 (methylcrotonoyl-CoA carboxylase 1) Rattus norvegicus
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Symbol: Mccc1
Name: methylcrotonoyl-CoA carboxylase 1
Description: Predicted to contribute to methylcrotonoyl-CoA carboxylase activity. Predicted to be involved in leucine catabolic process. Predicted to localize to the methylcrotonoyl-CoA carboxylase complex and mitochondrial matrix. Human ortholog(s) of this gene implicated in 3-Methylcrotonyl-CoA carboxylase deficiency. Orthologous to human MCCC1 (methylcrotonoyl-CoA carboxylase 1); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; LOC294972; MCCase subunit alpha; methylcrotonoyl-CoA carboxylase 1 (alpha); methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 1 (alpha); MGC95141
Orthologs:
Homo sapiens (human) : MCCC1 (methylcrotonoyl-CoA carboxylase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mccc1 (methylcrotonoyl-Coenzyme A carboxylase 1 (alpha))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mccc1 (methylcrotonoyl-CoA carboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MCCC1 (methylcrotonoyl-CoA carboxylase 1)
Canis lupus familiaris (dog) : MCCC1 (methylcrotonoyl-CoA carboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mccc1 (methylcrotonoyl-CoA carboxylase 1)
Sus scrofa (pig) : MCCC1 (methylcrotonoyl-CoA carboxylase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02122,550,777 - 122,690,540 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02142,186,426 - 142,203,853 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02142,300,575 - 142,317,803 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42122,416,660 - 122,469,557 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12122,361,622 - 122,414,519 (-)NCBI
Celera2113,761,210 - 113,811,967 (-)NCBICelera
Cytogenetic Map2q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mccc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310615
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.