Esyt2 (extended synaptotagmin 2) - Rat Genome Database

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Gene: Esyt2 (extended synaptotagmin 2) Rattus norvegicus
Analyze
Symbol: Esyt2
Name: extended synaptotagmin 2
RGD ID: 1565705
Description: Predicted to enable calcium ion binding activity; identical protein binding activity; and phospholipid binding activity. Predicted to be involved in endoplasmic reticulum-plasma membrane tethering and lipid transport. Predicted to be located in endoplasmic reticulum-plasma membrane contact site. Predicted to be integral component of plasma membrane. Predicted to be extrinsic component of cytoplasmic side of plasma membrane and intrinsic component of endoplasmic reticulum membrane. Orthologous to human ESYT2 (extended synaptotagmin 2); INTERACTS WITH acrylamide; bisphenol A; caffeine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: extended synaptotagmin protein 2; extended synaptotagmin-2; extended synaptotagmin-like protein 2; LOC102549308; LOC299488; RGD1565705; similar to chr2 synaptotagmin; uncharacterized LOC102549308
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26137,219,653 - 137,312,590 (+)NCBI
Rnor_6.0 Ensembl6144,156,175 - 144,245,545 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06144,156,021 - 144,248,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06153,092,679 - 153,184,797 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,566,626 - 143,657,881 (+)NCBIRGSC3.4rn4RGSC3.4
Celera6134,884,876 - 134,977,669 (+)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

Additional References at PubMed
PMID:17360437   PMID:19893752   PMID:19946888   PMID:22206666   PMID:23791178   PMID:24373768   PMID:24847877   PMID:25468996   PMID:27044890   PMID:30220461  


Genomics

Comparative Map Data
Esyt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26137,219,653 - 137,312,590 (+)NCBI
Rnor_6.0 Ensembl6144,156,175 - 144,245,545 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06144,156,021 - 144,248,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06153,092,679 - 153,184,797 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,566,626 - 143,657,881 (+)NCBIRGSC3.4rn4RGSC3.4
Celera6134,884,876 - 134,977,669 (+)NCBICelera
Cytogenetic Map6q33NCBI
ESYT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7158,730,995 - 158,830,253 (-)EnsemblGRCh38hg38GRCh38
GRCh387158,730,997 - 158,829,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377158,523,688 - 158,622,200 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367158,216,450 - 158,315,080 (-)NCBINCBI36hg18NCBI36
Celera7152,956,246 - 153,054,446 (-)NCBI
Cytogenetic Map7q36.3NCBI
HuRef7152,262,280 - 152,361,043 (-)NCBIHuRef
CHM1_17158,532,008 - 158,630,482 (-)NCBICHM1_1
CRA_TCAGchr7v27157,728,008 - 157,826,023 (-)NCBI
Esyt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912116,242,903 - 116,354,555 (+)NCBIGRCm39mm39
GRCm39 Ensembl12116,244,816 - 116,354,670 (+)Ensembl
GRCm3812116,279,283 - 116,390,935 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12116,281,196 - 116,391,050 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712117,519,695 - 117,611,571 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612110,482,451 - 110,573,901 (+)NCBImm8
MGSCv3612116,723,231 - 116,815,107 (+)NCBImm8
Cytogenetic Map12F2NCBI
cM Map1262.65NCBI
Esyt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955579971,653 - 1,022,661 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955579971,556 - 1,052,575 (-)NCBIChiLan1.0ChiLan1.0
ESYT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17162,006,323 - 162,102,994 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7162,009,537 - 162,104,844 (-)Ensemblpanpan1.1panPan2
ESYT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11620,719,115 - 20,802,991 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1620,718,499 - 20,811,468 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1621,223,940 - 21,305,821 (-)NCBI
ROS_Cfam_1.01622,450,105 - 22,533,819 (-)NCBI
UMICH_Zoey_3.11620,817,634 - 20,899,737 (-)NCBI
UNSW_CanFamBas_1.01621,401,967 - 21,484,081 (-)NCBI
UU_Cfam_GSD_1.01621,456,093 - 21,538,247 (-)NCBI
Esyt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118567,316 - 627,505 (+)NCBI
SpeTri2.0NW_004936856641,863 - 702,152 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESYT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18565,132 - 643,306 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118565,137 - 643,308 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218801,262 - 864,983 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESYT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121126,757,748 - 126,792,986 (-)NCBI
ChlSab1.1 Ensembl21126,754,260 - 126,793,320 (-)Ensembl
Vero_WHO_p1.0NW_02366607223,156,031 - 23,214,766 (-)NCBI
Esyt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624800310,362 - 413,636 (+)NCBI

Position Markers
RH134571  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,312,302 - 137,312,484 (+)MAPPER
Rnor_6.06144,248,087 - 144,248,268NCBIRnor6.0
Rnor_5.06153,184,510 - 153,184,691UniSTSRnor5.0
RGSC_v3.46143,659,861 - 143,660,042UniSTSRGSC3.4
Celera6134,977,382 - 134,977,563UniSTS
RH 3.4 Map6919.9UniSTS
Cytogenetic Map6q33UniSTS
AI229438  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,311,731 - 137,311,948 (+)MAPPER
Rnor_6.06144,247,516 - 144,247,732NCBIRnor6.0
Rnor_5.06153,183,939 - 153,184,155UniSTSRnor5.0
RGSC_v3.46143,659,290 - 143,659,506UniSTSRGSC3.4
Celera6134,976,811 - 134,977,027UniSTS
RH 3.4 Map6919.0UniSTS
Cytogenetic Map6q33UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6117355600147991367Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6127286494144745573Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6104363890147991367Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
2312560Pur20Proteinuria QTL 202.10.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6130561943144745573Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6127286494147249902Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6127286494147991367Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)699273921144792678Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)6101207574147991367Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)699273921144273921Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:20
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000006582
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 53 37 19 37 8 10 74 35 41 11 8
Low 1 4 4 4 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_002726849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000006582   ⟹   ENSRNOP00000006582
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6144,156,175 - 144,245,545 (+)Ensembl
RefSeq Acc Id: NM_001271169   ⟹   NP_001258098
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,219,707 - 137,312,590 (+)NCBI
RefSeq Acc Id: XM_039112112   ⟹   XP_038968040
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,219,657 - 137,312,584 (+)NCBI
RefSeq Acc Id: XM_039112113   ⟹   XP_038968041
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,219,657 - 137,312,584 (+)NCBI
RefSeq Acc Id: XM_039112114   ⟹   XP_038968042
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,219,657 - 137,312,584 (+)NCBI
RefSeq Acc Id: XM_039112115   ⟹   XP_038968043
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,219,655 - 137,312,584 (+)NCBI
RefSeq Acc Id: XM_039112116   ⟹   XP_038968044
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,220,011 - 137,312,584 (+)NCBI
RefSeq Acc Id: XM_039112118   ⟹   XP_038968046
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,261,363 - 137,312,584 (+)NCBI
RefSeq Acc Id: XM_039112119   ⟹   XP_038968047
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,219,653 - 137,298,051 (+)NCBI
RefSeq Acc Id: XM_039112120   ⟹   XP_038968048
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,219,654 - 137,298,051 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSRNOP00000006582   ⟸   ENSRNOT00000006582
RefSeq Acc Id: XP_038968047   ⟸   XM_039112119
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038968048   ⟸   XM_039112120
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038968043   ⟸   XM_039112115
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038968040   ⟸   XM_039112112
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038968041   ⟸   XM_039112113
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038968042   ⟸   XM_039112114
- Peptide Label: isoform X3
RefSeq Acc Id: NP_001258098   ⟸   NM_001271169
RefSeq Acc Id: XP_038968044   ⟸   XM_039112116
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038968046   ⟸   XM_039112118
- Peptide Label: isoform X6
Protein Domains
C2   SMP-LTD

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694909
Promoter ID:EPDNEW_R5432
Type:initiation region
Name:Esyt2_1
Description:extended synaptotagmin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06144,156,083 - 144,156,143EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565705 AgrOrtholog
Ensembl Genes ENSRNOG00000032391 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006582 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006582 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_Ca-dep UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  C2C_KIAA1228 UniProtKB/TrEMBL
  Ext_Synaptotagmin_C2A UniProtKB/TrEMBL
  Ext_Synaptotagmin_C2B UniProtKB/TrEMBL
  SMP_LBD UniProtKB/TrEMBL
  Synaptotagmin_SMP UniProtKB/TrEMBL
NCBI Gene 299488 ENTREZGENE
Pfam PF00168 UniProtKB/TrEMBL
  SMP_LBD UniProtKB/TrEMBL
PhenoGen Esyt2 PhenoGen
PROSITE PS50004 UniProtKB/TrEMBL
  SMP UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
UniProt D3ZJ32_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Esyt2  extended synaptotagmin 2  LOC102549308  uncharacterized LOC102549308  Data Merged 737654 PROVISIONAL
2016-06-22 Esyt2  extended synaptotagmin 2  Esyt2  extended synaptotagmin protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-15 Esyt2  extended synaptotagmin protein 2  Esyt2  extended synaptotagmin-like protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102549308  uncharacterized LOC102549308      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-10-12 Esyt2  extended synaptotagmin-like protein 2  RGD1565705  similar to chr2 synaptotagmin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565705  similar to chr2 synaptotagmin   RGD1565705_predicted  similar to chr2 synaptotagmin (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565705_predicted  similar to chr2 synaptotagmin (predicted)  LOC299488  similar to chr2 synaptotagmin  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC299488  similar to chr2 synaptotagmin      Symbol and Name status set to provisional 70820 PROVISIONAL