Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Esyt2 | Rat | (-)-demecolcine | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of ESYT2 mRNA | CTD | PMID:23649840 | Esyt2 | Rat | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | ESYT2 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to ESYT2 protein | CTD | PMID:32991956 | Esyt2 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ESYT2 mRNA | CTD | PMID:32145629 | Esyt2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Esyt2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ESYT2 mRNA | CTD | PMID:33387578 | Esyt2 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Esyt2 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [pyrogallol 1 more ... | CTD | PMID:38598786 | Esyt2 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of ESYT2 protein | CTD | PMID:31675489 | Esyt2 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of ESYT2 gene | CTD | PMID:31601247 | Esyt2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of ESYT2 protein | CTD | PMID:34186270 | Esyt2 | Rat | acrolein | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ESYT2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ESYT2 mRNA | CTD | PMID:32699268 | Esyt2 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of ESYT2 mRNA | CTD | PMID:28959563 | Esyt2 | Rat | aflatoxin B1 | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of ESYT2 mRNA | CTD | PMID:21641981 | Esyt2 | Rat | alpha-pinene | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ESYT2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ESYT2 mRNA | CTD | PMID:32699268 | Esyt2 | Rat | antirheumatic drug | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ESYT2 mRNA | CTD | PMID:24449571 | Esyt2 | Rat | arsane | affects methylation | ISO | ESYT2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ESYT2 gene | CTD | PMID:25304211 | Esyt2 | Rat | arsenic atom | affects methylation | ISO | ESYT2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ESYT2 gene | CTD | PMID:25304211 | Esyt2 | Rat | arsenite(3-) | decreases expression | ISO | Esyt2 (Mus musculus) | 6480464 | arsenite results in decreased expression of ESYT2 protein | CTD | PMID:37955338 | Esyt2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | Esyt2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ESYT2 mRNA | CTD | PMID:25181051 | Esyt2 | Rat | bisphenol A | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ESYT2 protein | CTD | PMID:34186270 | Esyt2 | Rat | bisphenol A | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ESYT2 protein | CTD | PMID:31675489 | Esyt2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ESYT2 mRNA | CTD | PMID:32145629 | Esyt2 | Rat | bisphenol AF | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of ESYT2 protein | CTD | PMID:34186270 | Esyt2 | Rat | Bisphenol B | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of ESYT2 protein | CTD | PMID:34186270 | Esyt2 | Rat | bortezomib | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of ESYT2 mRNA | CTD | PMID:20977926 | Esyt2 | Rat | caffeine | decreases expression | EXP | | 6480464 | Caffeine results in decreased expression of ESYT2 mRNA | CTD | PMID:20864626 | Esyt2 | Rat | caffeine | affects phosphorylation | ISO | ESYT2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of ESYT2 protein | CTD | PMID:35688186 | Esyt2 | Rat | calyculin a | increases expression | ISO | Esyt2 (Mus musculus) | 6480464 | calyculin A results in increased expression of ESYT2 mRNA | CTD | PMID:25270620 | Esyt2 | Rat | CGP 52608 | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ESYT2 gene] | CTD | PMID:28238834 | Esyt2 | Rat | cisplatin | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of ESYT2 mRNA | CTD | PMID:27392435 | Esyt2 | Rat | cisplatin | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ESYT2 mRNA | CTD | PMID:27392435 | Esyt2 | Rat | copper(II) sulfate | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ESYT2 mRNA | CTD | PMID:19549813 | Esyt2 | Rat | coumarin | increases phosphorylation | ISO | ESYT2 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of ESYT2 protein | CTD | PMID:35688186 | Esyt2 | Rat | coumestrol | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of ESYT2 mRNA | CTD | PMID:19167446 | Esyt2 | Rat | DDE | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of ESYT2 mRNA | CTD | PMID:38568856 | Esyt2 | Rat | decabromodiphenyl ether | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of ESYT2 protein | CTD | PMID:31675489 | Esyt2 | Rat | dibutyl phthalate | increases expression | ISO | Esyt2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of ESYT2 mRNA | CTD | PMID:21266533 | Esyt2 | Rat | dioxygen | multiple interactions | ISO | Esyt2 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of ESYT2 mRNA | CTD | PMID:30529165 | Esyt2 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of ESYT2 mRNA | CTD | PMID:33729688 | Esyt2 | Rat | disodium selenite | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of ESYT2 mRNA | CTD | PMID:18175754 | Esyt2 | Rat | dorsomorphin | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Esyt2 | Rat | doxorubicin | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of ESYT2 mRNA | CTD | PMID:29803840 | Esyt2 | Rat | ethyl methanesulfonate | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of ESYT2 mRNA | CTD | PMID:23649840 | Esyt2 | Rat | FR900359 | affects phosphorylation | ISO | ESYT2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ESYT2 protein | CTD | PMID:37730182 | Esyt2 | Rat | fulvestrant | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of ESYT2 gene | CTD | PMID:31601247 | Esyt2 | Rat | furfural | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [pyrogallol 1 more ... | CTD | PMID:38598786 | Esyt2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ESYT2 mRNA | CTD | PMID:33387578 | Esyt2 | Rat | ivermectin | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ESYT2 protein | CTD | PMID:32959892 | Esyt2 | Rat | menadione | affects expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ESYT2 mRNA | CTD | PMID:20044591 | Esyt2 | Rat | methoxyacetic acid | decreases expression | EXP | | 6480464 | methoxyacetic acid results in decreased expression of ESYT2 mRNA | CTD | PMID:20864626 | Esyt2 | Rat | methyl methanesulfonate | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of ESYT2 mRNA | CTD | PMID:23649840 | Esyt2 | Rat | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of ESYT2 mRNA | CTD | PMID:20864626 | Esyt2 | Rat | methylmercury chloride | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of ESYT2 mRNA | CTD | PMID:28001369 | Esyt2 | Rat | Monobutylphthalate | decreases expression | EXP | | 6480464 | monobutyl phthalate results in decreased expression of ESYT2 mRNA | CTD | PMID:20864626 | Esyt2 | Rat | ozone | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ESYT2 mRNA more ... | CTD | PMID:32699268 | Esyt2 | Rat | phenylmercury acetate | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of ESYT2 mRNA | CTD | PMID:26272509 | Esyt2 | Rat | phenylmercury acetate | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ESYT2 mRNA | CTD | PMID:27188386 | Esyt2 | Rat | potassium dichromate | decreases expression | ISO | Esyt2 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of ESYT2 mRNA | CTD | PMID:23608068 | Esyt2 | Rat | SB 431542 | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Esyt2 | Rat | sodium arsenite | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ESYT2 mRNA | CTD | PMID:38568856 | Esyt2 | Rat | sodium chloride | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of ESYT2 protein more ... | CTD | PMID:38598786 | Esyt2 | Rat | sulforaphane | multiple interactions | ISO | Esyt2 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of ESYT2 mRNA | CTD | PMID:30529165 | Esyt2 | Rat | sunitinib | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ESYT2 mRNA | CTD | PMID:31533062 | Esyt2 | Rat | temozolomide | decreases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of ESYT2 mRNA | CTD | PMID:31758290 | Esyt2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ESYT2 mRNA | CTD | PMID:34492290 | Esyt2 | Rat | titanium dioxide | increases methylation | ISO | Esyt2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ESYT2 promoter | CTD | PMID:35295148 | Esyt2 | Rat | trichostatin A | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ESYT2 mRNA | CTD | PMID:24935251 and PMID:26272509 | Esyt2 | Rat | trichostatin A | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ESYT2 mRNA | CTD | PMID:27188386 | Esyt2 | Rat | triphenyl phosphate | affects expression | ISO | ESYT2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ESYT2 mRNA | CTD | PMID:37042841 | Esyt2 | Rat | trovafloxacin | decreases expression | ISO | Esyt2 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of ESYT2 mRNA | CTD | PMID:35537566 | Esyt2 | Rat | valproic acid | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ESYT2 mRNA | CTD | PMID:27188386 | Esyt2 | Rat | valproic acid | increases expression | ISO | ESYT2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ESYT2 mRNA | CTD | PMID:23179753 more ... | Esyt2 | Rat | zinc atom | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ESYT2 mRNA | CTD | PMID:18593933 | Esyt2 | Rat | zinc(0) | multiple interactions | ISO | ESYT2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ESYT2 mRNA | CTD | PMID:18593933 | |