Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sinhcaf | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of FAM60A mRNA | CTD | PMID:32145629 | Sinhcaf | Rat | 17beta-estradiol | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Estradiol results in increased expression of SINHCAF mRNA | CTD | PMID:31614463 | Sinhcaf | Rat | 2,3,4,7,8-Pentachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:21724226 | Sinhcaf | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Sinhcaf (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to TERA promoter] | CTD | PMID:19654925 | Sinhcaf | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SINHCAF mRNA | CTD | PMID:21889950 | Sinhcaf | Rat | 2-hydroxypropanoic acid | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of SINHCAF mRNA | CTD | PMID:30851411 | Sinhcaf | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TERA mRNA | CTD | PMID:20188158 | Sinhcaf | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Fenretinide results in increased expression of SINHCAF mRNA | CTD | PMID:28973697 | Sinhcaf | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SINHCAF mRNA | CTD | PMID:24780913 | Sinhcaf | Rat | aflatoxin B1 | decreases methylation | ISO | SINHCAF (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SINHCAF gene | CTD | PMID:27153756 | Sinhcaf | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of SINHCAF mRNA | CTD | PMID:38685447 | Sinhcaf | Rat | arsenite(3-) | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to SINHCAF mRNA] | CTD | PMID:32406909 | Sinhcaf | Rat | benzo[a]pyrene | increases methylation | ISO | SINHCAF (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FAM60A promoter | CTD | PMID:27901495 | Sinhcaf | Rat | benzo[a]pyrene | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SINHCAF mRNA | CTD | PMID:32234424 | Sinhcaf | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Sinhcaf | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SINHCAF mRNA | CTD | PMID:25181051 | Sinhcaf | Rat | bisphenol A | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SINHCAF gene | CTD | PMID:31601247 | Sinhcaf | Rat | bisphenol A | decreases methylation | ISO | SINHCAF (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of SINHCAF gene | CTD | PMID:31601247 | Sinhcaf | Rat | butan-1-ol | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SINHCAF mRNA | CTD | PMID:29432896 | Sinhcaf | Rat | cadmium dichloride | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of SINHCAF mRNA | CTD | PMID:26472689 | Sinhcaf | Rat | cadmium dichloride | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of SINHCAF mRNA | CTD | PMID:38568856 | Sinhcaf | Rat | CGP 52608 | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to FAM60A gene] | CTD | PMID:28238834 | Sinhcaf | Rat | chlordecone | decreases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Chlordecone results in decreased expression of SINHCAF mRNA | CTD | PMID:29980752 | Sinhcaf | Rat | choline | multiple interactions | ISO | Sinhcaf (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TERA mRNA | CTD | PMID:20938992 | Sinhcaf | Rat | cisplatin | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in increased expression of SINHCAF mRNA | CTD | PMID:21858171 | Sinhcaf | Rat | copper(II) sulfate | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SINHCAF mRNA | CTD | PMID:19549813 | Sinhcaf | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of SINHCAF mRNA | CTD | PMID:26577399 | Sinhcaf | Rat | cyclosporin A | increases methylation | ISO | SINHCAF (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of SINHCAF promoter | CTD | PMID:27989131 | Sinhcaf | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of SINHCAF mRNA | CTD | PMID:21266533 | Sinhcaf | Rat | dibutyl phthalate | increases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of SINHCAF mRNA | CTD | PMID:21266533 | Sinhcaf | Rat | dorsomorphin | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Sinhcaf | Rat | doxifluridine | increases response to substance | ISO | SINHCAF (Homo sapiens) | 6480464 | SINHCAF protein results in increased susceptibility to doxifluridine | CTD | PMID:16734730 | Sinhcaf | Rat | doxorubicin | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SINHCAF mRNA | CTD | PMID:29803840 | Sinhcaf | Rat | epoxiconazole | decreases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of SINHCAF mRNA | CTD | PMID:35436446 | Sinhcaf | Rat | folic acid | multiple interactions | ISO | Sinhcaf (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TERA mRNA | CTD | PMID:20938992 | Sinhcaf | Rat | fulvestrant | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SINHCAF gene | CTD | PMID:31601247 | Sinhcaf | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of SINHCAF mRNA | CTD | PMID:27387713 | Sinhcaf | Rat | hydrogen sulfide | decreases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Hydrogen Sulfide results in decreased expression of FAM60A mRNA | CTD | PMID:31843631 | Sinhcaf | Rat | L-methionine | multiple interactions | ISO | Sinhcaf (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TERA mRNA | CTD | PMID:20938992 | Sinhcaf | Rat | lead(0) | affects expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Lead affects the expression of SINHCAF mRNA | CTD | PMID:28903495 | Sinhcaf | Rat | leflunomide | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | leflunomide results in increased expression of SINHCAF mRNA | CTD | PMID:28988120 | Sinhcaf | Rat | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of SINHCAF mRNA | CTD | PMID:28801915 | Sinhcaf | Rat | manganese(II) chloride | increases methylation | EXP | | 6480464 | manganese chloride results in increased methylation of SINHCAF gene | CTD | PMID:28801915 | Sinhcaf | Rat | menadione | affects expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of SINHCAF mRNA | CTD | PMID:20044591 | Sinhcaf | Rat | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of SINHCAF mRNA | CTD | PMID:23665939 | Sinhcaf | Rat | paracetamol | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SINHCAF mRNA | CTD | PMID:21420995 | Sinhcaf | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SINHCAF mRNA | CTD | PMID:33387578 | Sinhcaf | Rat | paracetamol | affects expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Acetaminophen affects the expression of SINHCAF mRNA | CTD | PMID:17562736 | Sinhcaf | Rat | phenylmercury acetate | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of SINHCAF mRNA | CTD | PMID:26272509 | Sinhcaf | Rat | phenylmercury acetate | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SINHCAF mRNA | CTD | PMID:27188386 | Sinhcaf | Rat | piroxicam | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in increased expression of SINHCAF mRNA | CTD | PMID:21858171 | Sinhcaf | Rat | rac-lactic acid | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of SINHCAF mRNA | CTD | PMID:30851411 | Sinhcaf | Rat | SB 431542 | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Sinhcaf | Rat | sodium arsenate | increases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SINHCAF mRNA | CTD | PMID:21795629 | Sinhcaf | Rat | sodium arsenite | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SINHCAF mRNA | CTD | PMID:38568856 | Sinhcaf | Rat | sunitinib | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SINHCAF mRNA | CTD | PMID:31533062 | Sinhcaf | Rat | temozolomide | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Temozolomide results in increased expression of SINHCAF mRNA | CTD | PMID:31758290 | Sinhcaf | Rat | tetrachloromethane | affects expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of SINHCAF mRNA | CTD | PMID:17484886 | Sinhcaf | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SINHCAF mRNA | CTD | PMID:23411599 and PMID:34492290 | Sinhcaf | Rat | titanium dioxide | increases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | titanium dioxide results in increased expression of FAM60A mRNA | CTD | PMID:29264374 | Sinhcaf | Rat | titanium dioxide | increases methylation | ISO | Sinhcaf (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of FAM60A gene and titanium dioxide results in increased methylation of FAM60A promoter | CTD | PMID:35295148 | Sinhcaf | Rat | titanium dioxide | decreases methylation | ISO | Sinhcaf (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of FAM60A gene | CTD | PMID:35295148 | Sinhcaf | Rat | torcetrapib | increases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | torcetrapib results in increased expression of SINHCAF mRNA | CTD | PMID:23228038 | Sinhcaf | Rat | trichostatin A | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of SINHCAF mRNA | CTD | PMID:24935251 and PMID:26272509 | Sinhcaf | Rat | trichostatin A | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SINHCAF mRNA | CTD | PMID:27188386 | Sinhcaf | Rat | triphenyl phosphate | affects expression | ISO | SINHCAF (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SINHCAF mRNA | CTD | PMID:37042841 | Sinhcaf | Rat | triptonide | affects expression | ISO | Sinhcaf (Mus musculus) | 6480464 | triptonide affects the expression of SINHCAF mRNA | CTD | PMID:33045310 | Sinhcaf | Rat | valproic acid | decreases expression | ISO | Sinhcaf (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of TERA mRNA | CTD | PMID:20546886 | Sinhcaf | Rat | valproic acid | decreases expression | ISO | SINHCAF (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SINHCAF mRNA | CTD | PMID:23179753 more ... | Sinhcaf | Rat | valproic acid | multiple interactions | ISO | SINHCAF (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SINHCAF mRNA | CTD | PMID:27188386 | |