Scap (SREBF chaperone) - Rat Genome Database

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Gene: Scap (SREBF chaperone) Rattus norvegicus
Analyze
Symbol: Scap
Name: SREBF chaperone
RGD ID: 1309378
Description: Predicted to enable sterol binding activity. Involved in response to vitamin B3. Part of protein-containing complex. Biomarker of end stage renal disease. Orthologous to human SCAP (SREBF chaperone); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC301024; SREBP cleavage activating protein; SREBP cleavage-activating protein; sterol regulatory element-binding protein cleavage-activating protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,184,366 - 119,239,086 (+)NCBIGRCr8
mRatBN7.28110,306,026 - 110,360,677 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,306,031 - 110,360,666 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,921,501 - 115,976,170 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08114,120,688 - 114,175,360 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,963,481 - 112,018,151 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,551,869 - 118,628,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,570,503 - 118,628,651 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,895,671 - 117,972,292 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,706,479 - 114,761,342 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,725,918 - 114,780,799 (+)NCBI
Celera8109,591,567 - 109,646,089 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Niacin improves renal lipid metabolism and slows progression in chronic kidney disease. Cho KH, etal., Biochim Biophys Acta. 2010 Jan;1800(1):6-15. Epub 2009 Oct 28.
2. Differential gene expression pattern of diabetic rat retinas after intravitreal injection of erythropoietin. Chu Q, etal., Clin Experiment Ophthalmol. 2011 Mar;39(2):142-51. doi: 10.1111/j.1442-9071.2010.02437.x.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been. Osborne TF and Espenshade PJ, Genes Dev. 2009 Nov 15;23(22):2578-91.
6. Modified HMG-CoA reductase and LDLr regulation is deeply involved in age-related hypercholesterolemia. Pallottini V, etal., J Cell Biochem. 2006 Aug 1;98(5):1044-53.
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles. Yellaturu CR, etal., J Biol Chem. 2009 Mar 20;284(12):7518-32. Epub 2009 Jan 21.
Additional References at PubMed
PMID:11358865   PMID:11726962   PMID:12242332   PMID:12477932   PMID:16054043   PMID:17203467   PMID:17666524   PMID:22337502  


Genomics

Comparative Map Data
Scap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,184,366 - 119,239,086 (+)NCBIGRCr8
mRatBN7.28110,306,026 - 110,360,677 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,306,031 - 110,360,666 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,921,501 - 115,976,170 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08114,120,688 - 114,175,360 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,963,481 - 112,018,151 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,551,869 - 118,628,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,570,503 - 118,628,651 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,895,671 - 117,972,292 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,706,479 - 114,761,342 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,725,918 - 114,780,799 (+)NCBI
Celera8109,591,567 - 109,646,089 (+)NCBICelera
Cytogenetic Map8q32NCBI
SCAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,413,681 - 47,477,127 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,413,681 - 47,477,126 (-)EnsemblGRCh38hg38GRCh38
GRCh37347,455,171 - 47,517,431 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,430,188 - 47,492,449 (-)NCBINCBI36Build 36hg18NCBI36
Celera347,393,823 - 47,458,772 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,498,135 - 47,563,088 (-)NCBIHuRef
CHM1_1347,405,412 - 47,467,423 (-)NCBICHM1_1
T2T-CHM13v2.0347,430,101 - 47,496,247 (-)NCBIT2T-CHM13v2.0
Scap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,162,356 - 110,214,017 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,162,356 - 110,214,018 (+)EnsemblGRCm39 Ensembl
GRCm389110,333,288 - 110,384,949 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,333,288 - 110,384,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,235,797 - 110,287,450 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,178,523 - 110,230,113 (+)NCBIMGSCv36mm8
Celera9110,062,305 - 110,113,905 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.91NCBI
Scap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,813,534 - 24,869,480 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542024,813,683 - 24,869,602 (+)NCBIChiLan1.0ChiLan1.0
SCAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,370,784 - 47,435,759 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,375,552 - 47,441,673 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,314,535 - 47,379,455 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,414,012 - 48,446,721 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,414,012 - 48,479,845 (-)Ensemblpanpan1.1panPan2
SCAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,418,507 - 41,485,681 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,418,536 - 41,487,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,335,033 - 41,402,084 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02041,901,526 - 41,968,598 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,901,549 - 41,968,593 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,143,535 - 41,210,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,544,714 - 41,611,716 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,825,295 - 41,892,343 (+)NCBIUU_Cfam_GSD_1.0
Scap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,575,434 - 201,631,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,122,042 - 1,180,297 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,124,573 - 1,180,219 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,253,268 - 30,320,526 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11330,253,262 - 30,320,625 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,483,930 - 33,551,346 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,821,809 - 8,887,538 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,818,980 - 8,850,202 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041158,240,615 - 158,318,574 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473073,927,010 - 73,975,337 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473073,926,978 - 73,975,337 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scap
90 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:113
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000028295
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat

Markers in Region
BE108733  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,329,343 - 110,329,549 (+)MAPPERmRatBN7.2
Rnor_6.08118,597,322 - 118,597,527NCBIRnor6.0
Rnor_5.08117,940,964 - 117,941,169UniSTSRnor5.0
RGSC_v3.48114,730,016 - 114,730,221UniSTSRGSC3.4
Celera8109,614,754 - 109,614,959UniSTS
RH 3.4 Map81191.6UniSTS
Cytogenetic Map8q32UniSTS
UniSTS:236259  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,360,304 - 110,360,447 (+)MAPPERmRatBN7.2
Rnor_6.08118,628,278 - 118,628,420NCBIRnor6.0
Rnor_5.08117,971,920 - 117,972,062UniSTSRnor5.0
RGSC_v3.48114,760,972 - 114,761,114UniSTSRGSC3.4
Celera8109,645,719 - 109,645,861UniSTS
Cytogenetic Map8q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 57 41 19 41 1 4 74 35 39 11 1
Low 8 7 7 2 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000028295   ⟹   ENSRNOP00000028295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,306,031 - 110,360,666 (+)Ensembl
Rnor_6.0 Ensembl8118,570,503 - 118,628,639 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090238   ⟹   ENSRNOP00000072003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl8118,570,569 - 118,628,651 (+)Ensembl
RefSeq Acc Id: NM_001100966   ⟹   NP_001094436
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88119,184,438 - 119,239,086 (+)NCBI
mRatBN7.28110,306,026 - 110,360,677 (+)NCBI
Rnor_6.08118,570,503 - 118,628,648 (+)NCBI
Rnor_5.08117,895,671 - 117,972,292 (+)NCBI
RGSC_v3.48114,706,479 - 114,761,342 (+)RGD
Celera8109,591,567 - 109,646,089 (+)RGD
Sequence:
RefSeq Acc Id: XM_017595597   ⟹   XP_017451086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88119,207,261 - 119,239,086 (+)NCBI
mRatBN7.28110,328,855 - 110,360,677 (+)NCBI
Rnor_6.08118,596,889 - 118,628,650 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039081248   ⟹   XP_038937176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88119,184,442 - 119,239,086 (+)NCBI
mRatBN7.28110,306,032 - 110,360,677 (+)NCBI
RefSeq Acc Id: XM_063265270   ⟹   XP_063121340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88119,184,442 - 119,239,086 (+)NCBI
RefSeq Acc Id: XM_063265271   ⟹   XP_063121341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88119,184,366 - 119,239,086 (+)NCBI
RefSeq Acc Id: NP_001094436   ⟸   NM_001100966
- UniProtKB: A2RRU4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017451086   ⟸   XM_017595597
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000072003   ⟸   ENSRNOT00000090238
RefSeq Acc Id: ENSRNOP00000028295   ⟸   ENSRNOT00000028295
RefSeq Acc Id: XP_038937176   ⟸   XM_039081248
- Peptide Label: isoform X1
- UniProtKB: A2RRU4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063121341   ⟸   XM_063265271
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121340   ⟸   XM_063265270
- Peptide Label: isoform X1
Protein Domains
SSD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2RRU4-F1-model_v2 AlphaFold A2RRU4 1-1276 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696329
Promoter ID:EPDNEW_R6854
Type:initiation region
Name:Scap_1
Description:SREBF chaperone
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08118,570,553 - 118,570,613EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309378 AgrOrtholog
BioCyc Gene G2FUF-29075 BioCyc
Ensembl Genes ENSRNOG00000020853 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028295 ENTREZGENE
  ENSRNOT00000028295.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7189794 IMAGE-MGC_LOAD
InterPro SCAP UniProtKB/Swiss-Prot
  SSD UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:301024 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156813 IMAGE-MGC_LOAD
NCBI Gene 301024 ENTREZGENE
PANTHER PTHR46378 UniProtKB/Swiss-Prot
  STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN UniProtKB/Swiss-Prot
Pfam Sterol-sensing UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Scap PhenoGen
PROSITE SSD UniProtKB/Swiss-Prot
  WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020853 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP Multidrug efflux transporter AcrB transmembrane domain UniProtKB/Swiss-Prot
  SSF50978 UniProtKB/Swiss-Prot
UniProt A2RRU4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Scap  SREBF chaperone  Scap_predicted  SREBP cleavage activating protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Scap_predicted  SREBP cleavage activating protein (predicted)      Symbol and Name status set to approved 70820 APPROVED