Tspan5 (tetraspanin 5) - Rat Genome Database

Name: Tspan5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Tspan5 (tetraspanin 5) Rattus norvegicus

Analyze

Symbol:

Tspan5

Name:

tetraspanin 5

RGD ID:

1303176

Description:

Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of Notch signaling pathway; protein localization to plasma membrane; and protein maturation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TSPAN5 (tetraspanin 5); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

tetraspan 5; tetraspanin-5; Tm4sf9; transmembrane 4 superfamily member 9; Tspan-5

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TSPAN5 (tetraspanin 5)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tspan5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tspan5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TSPAN5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TSPAN5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tspan5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TSPAN5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TSPAN5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tspan5 (tetraspanin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TSPAN17 (tetraspanin 17)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	TSPAN5 (tetraspanin 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tspan5 (tetraspanin 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tspan5b (tetraspanin 5b)	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	tspan5a (tetraspanin 5a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Tsp26A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tsp-12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	227,294,180 - 227,469,361 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	227,294,217 - 227,465,664 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	235,044,298 - 235,207,548 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	232,944,059 - 233,107,310 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	227,808,665 - 227,971,910 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	244,058,186 - 244,224,059 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	244,058,186 - 244,224,058 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	262,587,481 - 262,753,105 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	236,314,737 - 236,487,072 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	236,436,906 - 236,471,800 (+)	NCBI
Celera	2	219,449,291 - 219,612,375 (+)	NCBI		Celera
Cytogenetic Map	2	q44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4-hydroxyphenyl retinamide (ISO)

4-vinylcyclohexene dioxide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

furan (EXP)

gentamycin (EXP)

hydrogen peroxide (ISO)

L-methionine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

Licochalcone B (ISO)

menadione (ISO)

mifepristone (EXP)

N,N-diethyl-m-toluamide (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

permethrin (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

rimonabant (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

thioacetamide (EXP)

topotecan (EXP)

trichostatin A (ISO)

triclosan (ISO)

urethane (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (TAS)

cell population proliferation (TAS)

positive regulation of Notch signaling pathway (ISO)

protein localization to plasma membrane (IBA,ISO)

protein maturation (IBA,ISO)

Cellular Component

membrane (IEA,TAS)

plasma membrane (IBA,ISO)

Molecular Function

enzyme binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Specific tetraspanin functions.	Hemler ME J Cell Biol 2001 Dec 24;155(7):1103-7. Epub 2001 Dec 24.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:23035126	PMID:23091066

Genomics

Comparative Map Data

Tspan5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	227,294,180 - 227,469,361 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	227,294,217 - 227,465,664 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	235,044,298 - 235,207,548 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	232,944,059 - 233,107,310 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	227,808,665 - 227,971,910 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	244,058,186 - 244,224,059 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	244,058,186 - 244,224,058 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	262,587,481 - 262,753,105 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	236,314,737 - 236,487,072 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	236,436,906 - 236,471,800 (+)	NCBI
Celera	2	219,449,291 - 219,612,375 (+)	NCBI		Celera
Cytogenetic Map	2	q44	NCBI

TSPAN5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	98,470,367 - 98,658,611 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	4	98,470,367 - 98,658,611 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	99,391,518 - 99,579,762 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	99,612,421 - 99,798,750 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	96,686,187 - 96,874,635 (-)	NCBI		Celera
Cytogenetic Map	4	q23	NCBI
HuRef	4	95,128,912 - 95,317,094 (-)	NCBI		HuRef
CHM1_1	4	99,368,380 - 99,556,673 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	101,785,330 - 101,973,565 (-)	NCBI		T2T-CHM13v2.0

Tspan5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	138,447,609 - 138,610,194 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	138,447,956 - 138,613,666 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	138,741,848 - 138,904,433 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	138,742,195 - 138,907,905 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	138,405,159 - 138,567,388 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	138,679,582 - 138,841,811 (+)	NCBI		MGSCv36	mm8
Celera	3	145,169,944 - 145,332,005 (+)	NCBI		Celera
Cytogenetic Map	3	H1	NCBI

Tspan5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	8,725,761 - 8,759,785 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955405	8,725,761 - 8,759,784 (-)	NCBI	ChiLan1.0	ChiLan1.0

TSPAN5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	4	101,536,950 - 101,717,526 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	101,536,950 - 101,717,228 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	4	90,872,988 - 91,052,345 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

TSPAN5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	20,707,449 - 20,878,441 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	20,709,539 - 20,878,426 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	21,053,555 - 21,228,770 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	20,890,676 - 21,061,654 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	20,890,676 - 21,061,716 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	20,859,415 - 21,029,584 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	20,685,159 - 20,855,851 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	19,041,028 - 19,211,757 (+)	NCBI		UU_Cfam_GSD_1.0

Tspan5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	20,832,188 - 20,999,948 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936717	49,752 - 217,654 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936717	49,797 - 217,567 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TSPAN5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	121,657,325 - 121,843,242 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	121,657,320 - 121,843,296 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	130,843,562 - 131,031,806 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TSPAN5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	46,610,841 - 46,788,761 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	46,609,602 - 46,788,704 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	25,042,011 - 25,220,101 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tspan5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624757	26,557,898 - 26,733,209 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624757	26,558,052 - 26,732,932 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tspan5
1195 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	688
Count of miRNA genes:	297
Interacting mature miRNAs:	378
Transcripts:	ENSRNOT00000021381
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	189599258	234599258	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189599258	234599258	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	193452645	245889826	Rat
1598813	Memor9	Memory QTL 9	2.7		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	199341726	234244620	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	200990457	245990457	Rat
2298479	Eau5	Experimental allergic uveoretinitis QTL 5		0.0021	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	2	202446871	237938339	Rat
7207490	Bss111	Bone structure and strength QTL 111	6.4		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	2	211744537	249053267	Rat
7207482	Bss107	Bone structure and strength QTL 107	7		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	2	211744537	249053267	Rat
7207484	Bss108	Bone structure and strength QTL 108	5.3		femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	2	211744537	249053267	Rat
1298075	Scl17	Serum cholesterol level QTL 17	3.4		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	211744537	249053267	Rat
1549836	Bss2	Bone structure and strength QTL 2	7.5		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	2	211744537	249053267	Rat
2317885	Alcrsp28	Alcohol response QTL 28	2.1	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	212828222	249053267	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	214226044	247136170	Rat
2313073	Bmd75	Bone mineral density QTL 75	4.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	2	215377404	237938339	Rat
1331767	Hrtrt12	Heart rate QTL 12	3.373		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	218414747	240841241	Rat
2293833	Kiddil8	Kidney dilation QTL 8	2.9		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	219753301	247136170	Rat
2293844	Kiddil7	Kidney dilation QTL 7	3.5		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	219753301	247136170	Rat
9587428	Epfw6	Epididymal fat weight QTL 6	7.47	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	2	223389739	249053267	Rat
7411555	Bw132	Body weight QTL 132		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	2	223389739	249053267	Rat

Markers in Region

RH137962

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	227,346,410 - 227,346,538 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	244,109,646 - 244,109,773	NCBI	Rnor6.0
Rnor_5.0	2	262,638,938 - 262,639,065	UniSTS	Rnor5.0
RGSC_v3.4	2	236,367,438 - 236,367,565	UniSTS	RGSC3.4
Celera	2	219,501,347 - 219,501,474	UniSTS
RH 3.4 Map	2	1594.2	UniSTS
Cytogenetic Map	2	q44	UniSTS

RH143648

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	227,292,606 - 227,292,751 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	244,056,582 - 244,056,726	NCBI	Rnor6.0
Rnor_5.0	2	262,585,877 - 262,586,021	UniSTS	Rnor5.0
RGSC_v3.4	2	236,313,131 - 236,313,275	UniSTS	RGSC3.4
Celera	2	219,447,687 - 219,447,831	UniSTS
RH 3.4 Map	2	1595.1	UniSTS
Cytogenetic Map	2	q44	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	14	18	18	5	18		2	74	35	37	11
Low	1	29	39	23	14	23	8	9			4		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF540877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000021381 ⟹ ENSRNOP00000021381

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	227,294,217 - 227,465,663 (+)	Ensembl
Rnor_6.0 Ensembl	2	244,058,186 - 244,224,058 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109275 ⟹ ENSRNOP00000077542

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	227,297,534 - 227,465,655 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109413 ⟹ ENSRNOP00000085734

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	227,294,217 - 227,465,663 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111381 ⟹ ENSRNOP00000084759

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	227,294,217 - 227,465,663 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000119237 ⟹ ENSRNOP00000081518

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	227,297,534 - 227,465,664 (+)	Ensembl

RefSeq Acc Id:

NM_001004090 ⟹ NP_001004090

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	227,294,217 - 227,465,664 (+)	NCBI
Rnor_6.0	2	244,058,186 - 244,224,059 (+)	NCBI
Rnor_5.0	2	262,587,481 - 262,753,105 (+)	NCBI
RGSC_v3.4	2	236,314,737 - 236,487,072 (+)	RGD
Celera	2	219,449,291 - 219,612,375 (+)	RGD

Sequence:

show sequence

AGAGGATGTCCGGGAAGCACTACAAGGGTCCTGAAGTCAGTTGTTGCATCAAATACTTCATTTT
TGGCTTCAATGTCATATTTTGGTTTTTGGGAATAACGTTTCTTGGAATTGGACTGTGGGCGTGG
AATGAAAAAGGTGTCCTGTCCAATATCTCGTCCATCACCGACCTCGGTGGCTTTGACCCAGTCT
GGCTTTTCCTCGTGGTGGGAGGAGTGATGTTCATTCTGGGGTTTGCAGGGTGCATCGGAGCACT
GCGGGAAAACACCTTCCTTCTCAAGTTTTTTTCTGTGTTCCTGGGAATTATTTTCTTCCTGGAA
CTCACTGCTGGGGTGTTGGCATTTGTTTTCAAAGACTGGATCAAAGACCAGCTGTATTTCTTTA
TTAACAACAACATCAGAGCCTACAGAGATGACATTGATCTGCAGAACCTCATAGACTTCACCCA
GGAATACTGGCAGTGCTGCGGGGCTTTTGGAGCTGACGATTGGAACCTAAATATTTACTTCAAC
TGCACAGACTCCAATGCAAGCCGAGAGCGATGTGGTGTGCCATTCTCCTGCTGCACTAAAGACC
CCGCGGAAGACGTCATCAACACTCAGTGTGGCTATGATGCCAGGCAAAAACCAGAAGTTGACCA
ACAGATTGTGATCTACACAAAAGGCTGTGTGCCCCAGTTTGAGAAGTGGCTACAGGACAATTTA
ACCATTGTGGCTGGTATTTTCATAGGAATTGCACTGCTTCAGATTTTTGGGATATGCCTGGCAC
AGAATTTGGTGAGTGACATTGAAGCTGTCAGGGCTAGCTGGTAGAACCCTGCAACCACTGCTGT
CAGACACTGGACTGATCCCCCCTCGCTGACTGACCCTCTGTGCGCCGGCCGGCTGATGGCGGGT
TGCAGAGACCTGGTCACAGGCTTGCAGTCTCACCCAATGGAGCTGCCAAGAACTTAACTTTCTG
CAGGGGTAGAACTTGGAAATGCTGCTCACGGACGGTCCCTTGAACAAGAAAAATGAAACAGCGT
GCAAGTCACCGAGTCGCTGTGCGGTGAATCTCTACTGTAGCCGTGAATTGATGGACAGATGGAT
GCTACCAGAAGGGGGGAAGGGGGAGGTTGGGCACCGCATGTACTTGACTTTATGGAGAATACAG
TGCTGTCCACATCTTGGCTAAAACTTGGGTCCTTATCCGCCAGGGCCAGGTGTCCTGAAATCCC
TCAATGCACATTTCCAGAAACTGTTGCAACTGTCCTCCAGAGAAGAAAACAGCGCCCCGGTGTT
CAGATTCTGCGAGGGGTGGAAGAGGTCATTTACAGAGTCCGCTCTCCTTCCCAAGTTTACCCCT
AAGAGAGCTGGGTGTTGGTGGCAAACTGAGGCCTTGATCCACATTTCCACAGGACTGATCTTTC
CTGAGTGGCCAGCCGGAGTCTGAGTTTTATCAGTGACATCTGAGGAGAAAATGAGGTTAATGAG
AGACACTAATTAAACACCCCCTCGCCCCACCTTATCAGACTATCTATCGGGTTCTTCTGATATT
CTGGAATATTCTGGGCTGCGTTTTGTGTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC
TCTCTTTCTCTCTCTTTTTATGACTGGTTGTTGTTTTGGTTCTTTTTTCGTCTCCCAAAGGCAA
AGGCTATATGACACAGTCCTCTGTAATGGTTTCCTATTCAACTTAAACAGTAAGTTTCTGTAGA
CACTTCACCTGCATGTACCGTGACGCCCCCAAACCCATGTTCTTTTCAGAGAGACATTTGCGAG
TGTTTGTTGGTGTTCACGCCTTGGGTGGTCGTGGCATGTTGTCCTAACTTTGTCTTCATACGCC
CCATGGGCTCACTGCCTCTCCCAGCATCCAGCTCGGCTTCTGTCCACTCCCCCATCCTCCATAA
AGCCCAGTTCCAAAGCAGGGTTGTCACGGTCAAAAAGCATTTAATGGGGCTTTCCTTTCTTTTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCCTTTTTGCAACTT
CAGTTTTGTTGTATATTAAATAAAAAAGCAAGCCAAGTATAGTGCATGGCAGAGCTCTGTCCTC
GCTGAGGTGGCCTCAGGGCAGTAACAAAGCACAAATATTTGTGAGTCTGCACCGAAAGCCCAGC
CAGGGTTCTGTGATGCTAGGTGGGAAGCCACCTCCGGGTCCTTCTCGTGCCCACCGGGAGGATG
GGATTGAGCCCCAGGCTTTCACCCAGCTTGTGATAACCCGTGGATGTTGCTTTCATGGGGAGCA
GATTTTAGTTTGTGGGTCGCTGGGAAGACCACAGCCTCTGTGATAGCAGCTCCTCTTTCGCCAG
CCAGCATTCTGAGCAATGCTATTTTCCACGTCCACAGCACGTGCGTGCATTGTGTGGCTGGTGG
ACACGGTCCACTCACAGGGAGGTCAGGCATTCCTCTGAAGTCTCATCTCCACAGTTTGGGTGTA
TGTGGCCCTGCATGTTTGTATTGGTGTCTGTTGTAGGTAGATATAGTCATTCCATCCATGGCTG
TGAGGTCACGTGACTTCACCTCTGCCCATACCACAGCCGTCGCTTGTGATGCCCTTCAACATGG
ACACGCGTGCTCTCGGATTGGCACTTGTGTCTTCTTTATTACCTCATTCTCCAGTGAACTACAT
CTGGCCAGTTGATTCAGAATCAGGCAAGATCCCCACCCCGTGGCACATACAGTGAAAGCCAAAA
CACAAGCCCAAGTGAGTTTTAAATTTTAATCACCCTTTATTTTTTACACTCGAGAGTGATTGTA
ATAAAAGCTGTCATTAATAAACTCGGTTCTACCTTAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039102726 ⟹ XP_038958654

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	227,294,180 - 227,469,361 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001004090	(Get FASTA)	NCBI Sequence Viewer
	XP_038958654	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00136	(Get FASTA)	NCBI Sequence Viewer
	AAQ11226	(Get FASTA)	NCBI Sequence Viewer
	EDL82328	(Get FASTA)	NCBI Sequence Viewer
	Q68VK5	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001004090 ⟸ NM_001004090

- UniProtKB:

Q498N9 (UniProtKB/Swiss-Prot), Q68VK5 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSGKHYKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWL
FLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFIN
NNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPA
EDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQN
LVSDIEAVRASW

hide sequence

RefSeq Acc Id:

ENSRNOP00000021381 ⟸ ENSRNOT00000021381

RefSeq Acc Id:	XP_038958654 ⟸ XM_039102726
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A2L2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000081518 ⟸ ENSRNOT00000119237

RefSeq Acc Id:

ENSRNOP00000085734 ⟸ ENSRNOT00000109413

RefSeq Acc Id:

ENSRNOP00000084759 ⟸ ENSRNOT00000111381

RefSeq Acc Id:

ENSRNOP00000077542 ⟸ ENSRNOT00000109275

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q68VK5-F1-model_v2	AlphaFold	Q68VK5	1-268	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303176	AgrOrtholog
BioCyc Gene	G2FUF-51047	BioCyc
Ensembl Genes	ENSRNOG00000015913	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000021381	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000077542.1	UniProtKB/TrEMBL
	ENSRNOP00000081518.1	UniProtKB/TrEMBL
	ENSRNOP00000084759	ENTREZGENE
	ENSRNOP00000084759.1	UniProtKB/TrEMBL
	ENSRNOP00000085734.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021381	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000109275.1	UniProtKB/TrEMBL
	ENSRNOT00000109413.1	UniProtKB/TrEMBL
	ENSRNOT00000111381	ENTREZGENE
	ENSRNOT00000111381.1	UniProtKB/TrEMBL
	ENSRNOT00000119237.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1450.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7315329	IMAGE-MGC_LOAD
InterPro	Tetraspanin	UniProtKB/Swiss-Prot
	Tetraspanin/Peripherin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tetraspanin_animals	UniProtKB/TrEMBL
	Tetraspanin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tetraspanin_EC2_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:362048	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114212	IMAGE-MGC_LOAD
NCBI Gene	362048	ENTREZGENE
PANTHER	PTHR19282	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Tetraspanin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Tspan5	PhenoGen
PIRSF	Tetraspanin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	TM4_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48652	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5Y5Y9_RAT	UniProtKB/TrEMBL
	A0A8I6A0T6_RAT	UniProtKB/TrEMBL
	A0A8I6A2L2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6G825_RAT	UniProtKB/TrEMBL
	Q498N9	ENTREZGENE
	Q68VK5	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q498N9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Tspan5	tetraspanin 5	Tm4sf9	transmembrane 4 superfamily member 9	Symbol and Name updated	1299863	APPROVED
2005-07-14	Tm4sf9	transmembrane 4 superfamily member 9			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar