Brd8 (bromodomain containing 8) - Rat Genome Database

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Gene: Brd8 (bromodomain containing 8) Rattus norvegicus
Analyze
Symbol: Brd8
Name: bromodomain containing 8
RGD ID: 1307003
Description: Predicted to enable nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of NuA4 histone acetyltransferase complex; Swr1 complex; and nucleosome. Biomarker of colorectal adenocarcinoma. Orthologous to human BRD8 (bromodomain containing 8); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; methapyrilene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bromodomain-containing protein 8; LOC291691; p120
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81826,455,824 - 26,504,106 (-)NCBIGRCr8
mRatBN7.21826,204,892 - 26,229,999 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,181,732 - 26,229,884 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,332,275 - 26,352,626 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,095,888 - 27,116,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01826,430,791 - 26,451,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01827,375,645 - 27,423,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1827,398,688 - 27,424,090 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,089,007 - 27,137,524 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,074,235 - 27,094,586 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11827,100,884 - 27,121,232 (-)NCBI
Celera1825,942,707 - 25,963,058 (-)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brd8Ratcolorectal adenocarcinoma disease_progressionIEP 9587763 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brd8Ratautosomal dominant intellectual developmental disorder 31  ISOBRD8 (Homo sapiens)8554872ClinVar Annotator: match by term: NEURODEVELOPMENTAL DISORDER WITH NEONATAL RESPIRATORY INSUFFICIENCY more ...ClinVarPMID:28492532
Brd8Ratfamilial adenomatous polyposis 1  ISOBRD8 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial adenomatous polyposis 1ClinVarPMID:17963004 more ...
Brd8RatHereditary Neoplastic Syndromes  ISOBRD8 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromeClinVarPMID:17963004 more ...
Brd8RatNeurodevelopmental Disorders  ISOBRD8 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Brd8RatSTING-associated vasculopathy with onset in infancy  ISOBRD8 (Homo sapiens)8554872ClinVar Annotator: match by term: STING-associated vasculopathy with onset in infancyClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brd8Ratendometriosis  ISOBRD8 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22138541

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brd8Rat(1->4)-beta-D-glucan multiple interactionsISOBrd8 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of BRD8 mRNACTDPMID:36331819
Brd8Rat1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactionsISOBrd8 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Brd8Rat1,2-dimethylhydrazine increases expressionISOBrd8 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of BRD8 mRNACTDPMID:22206623
Brd8Rat17alpha-ethynylestradiol multiple interactionsISOBrd8 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BRD8 mRNACTDPMID:17942748
Brd8Rat17beta-estradiol multiple interactionsISOBRD8 (Homo sapiens)6480464Estradiol promotes the reaction [ESR1 protein binds to BRD8 protein]CTDPMID:29389661 and PMID:32088792
Brd8Rat17beta-estradiol decreases expressionISOBRD8 (Homo sapiens)6480464Estradiol results in decreased expression of BRD8 mRNACTDPMID:31614463
Brd8Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsISOBRD8 (Homo sapiens)6480464[Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to BRD8 protein modified form]CTDPMID:28751236
Brd8Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOBrd8 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Brd8Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOBrd8 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Brd8Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOBrd8 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BRD8 mRNACTDPMID:17942748
Brd8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of BRD8 mRNACTDPMID:33387578
Brd8Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of BRD8 mRNACTDPMID:34747641
Brd8Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOBrd8 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of BRD8 mRNACTDPMID:21570461
Brd8Rat2,4,4'-trichlorobiphenyl multiple interactionsISOBrd8 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Brd8Rat4,4'-sulfonyldiphenol affects methylationISOBrd8 (Mus musculus)6480464bisphenol S affects the methylation of BRD8 geneCTDPMID:31683443
Brd8Rat4-hydroxyphenyl retinamide increases expressionISOBrd8 (Mus musculus)6480464Fenretinide results in increased expression of BRD8 mRNACTDPMID:28973697
Brd8Ratacrolein multiple interactionsISOBRD8 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BRD8 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BRD8 mRNACTDPMID:32699268
Brd8Rataflatoxin B1 increases expressionISOBrd8 (Mus musculus)6480464Aflatoxin B1 results in increased expression of BRD8 mRNACTDPMID:19770486
Brd8Rataflatoxin B1 decreases methylationISOBRD8 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of BRD8 intronCTDPMID:30157460
Brd8Ratall-trans-retinoic acid decreases expressionISOBRD8 (Homo sapiens)6480464Tretinoin results in decreased expression of BRD8 mRNACTDPMID:33167477

1 to 20 of 79 rows

Biological Process
1 to 9 of 9 rows

  
1 to 9 of 9 rows

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Brd8Ratmitochondrion located_inISOBRD8 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Brd8Ratmitochondrion located_inIEAUniProtKB:Q9H0E9 and ensembl:ENSP000002549001600115GO_REF:0000107EnsemblGO_REF:0000107
Brd8RatNuA4 histone acetyltransferase complex part_ofISOBRD8 (Homo sapiens)1624291 PMID:14966270 and PMID:27153538RGDPMID:14966270 and PMID:27153538
Brd8RatNuA4 histone acetyltransferase complex part_ofIEAUniProtKB:Q9H0E9 and ensembl:ENSP000002549001600115GO_REF:0000107EnsemblGO_REF:0000107
Brd8RatNuA4 histone acetyltransferase complex part_ofIBAFB:FBgn0039654 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Brd8Ratnucleoplasm located_inISOBRD8 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Brd8Ratnucleoplasm located_inIEAUniProtKB:Q9H0E9 and ensembl:ENSP000002549001600115GO_REF:0000107EnsemblGO_REF:0000107
Brd8Ratnucleosome part_ofISOBRD8 (Homo sapiens)1624291 PMID:27153538RGDPMID:27153538
Brd8Ratnucleosome part_ofIEAUniProtKB:Q9H0E9 and ensembl:ENSP000002549001600115GO_REF:0000107EnsemblGO_REF:0000107
Brd8Ratnucleus located_inISOBRD8 (Homo sapiens)1624291 PMID:25593309RGDPMID:25593309
Brd8Ratnucleus located_inIEAUniProtKB:Q9H0E9 and ensembl:ENSP000002549001600115GO_REF:0000107EnsemblGO_REF:0000107
Brd8RatSwr1 complex part_ofISOBRD8 (Homo sapiens)1624291 PMID:24463511RGDPMID:24463511
Brd8RatSwr1 complex part_ofIEAUniProtKB:Q9H0E9 and ensembl:ENSP000002549001600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 13 of 13 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Brd8RatINO80 family mediated chromatin remodeling pathway  ISOBRD8 (Homo sapiens)9495926 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
5. The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics. Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.
6. BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy. Yamada HY and Rao CV, Int J Oncol. 2009 Nov;35(5):1101-9.
7. Co-activator p120 is increased by gonadotropins in the rat ovary and enhances progesterone receptor activity. Yoshino M, etal., Reprod Biol Endocrinol. 2006 Oct 3;4:50.
PMID:14966270   PMID:22082260   PMID:24463511   PMID:33173987  



Brd8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81826,455,824 - 26,504,106 (-)NCBIGRCr8
mRatBN7.21826,204,892 - 26,229,999 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,181,732 - 26,229,884 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,332,275 - 26,352,626 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,095,888 - 27,116,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01826,430,791 - 26,451,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01827,375,645 - 27,423,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1827,398,688 - 27,424,090 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,089,007 - 27,137,524 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,074,235 - 27,094,586 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11827,100,884 - 27,121,232 (-)NCBI
Celera1825,942,707 - 25,963,058 (-)NCBICelera
Cytogenetic Map18p12NCBI
BRD8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385138,139,770 - 138,178,630 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5138,139,770 - 138,178,953 (-)EnsemblGRCh38hg38GRCh38
GRCh375137,475,459 - 137,514,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365137,503,358 - 137,542,257 (-)NCBINCBI36Build 36hg18NCBI36
Celera5133,596,763 - 133,635,647 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5132,666,482 - 132,705,356 (-)NCBIHuRef
CHM1_15136,908,168 - 136,946,981 (-)NCBICHM1_1
T2T-CHM13v2.05138,666,102 - 138,704,922 (-)NCBIT2T-CHM13v2.0
Brd8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391834,731,668 - 34,757,916 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1834,731,668 - 34,757,654 (-)EnsemblGRCm39 Ensembl
GRCm381834,598,611 - 34,624,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1834,598,615 - 34,624,601 (-)EnsemblGRCm38mm10GRCm38
MGSCv371834,758,269 - 34,784,464 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361834,723,416 - 34,749,611 (-)NCBIMGSCv36mm8
Celera1835,051,227 - 35,077,223 (-)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.69NCBI
Brd8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554182,232,842 - 2,275,875 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554182,232,853 - 2,275,812 (+)NCBIChiLan1.0ChiLan1.0
BRD8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24133,413,615 - 133,452,773 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15131,553,168 - 131,592,326 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05133,535,321 - 133,557,304 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15139,652,112 - 139,690,468 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5139,652,112 - 139,690,468 (-)Ensemblpanpan1.1panPan2
BRD8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11125,793,375 - 25,825,868 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1125,793,668 - 25,825,726 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1124,559,631 - 24,592,299 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01126,645,970 - 26,678,830 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1126,645,978 - 26,678,526 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11125,353,288 - 25,385,951 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01125,176,899 - 25,208,532 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01125,840,328 - 25,872,995 (-)NCBIUU_Cfam_GSD_1.0
Brd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213154,249,563 - 154,292,389 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365317,333,907 - 7,362,114 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365317,333,974 - 7,361,855 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRD8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2140,168,636 - 140,202,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12140,182,195 - 140,202,247 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22145,866,443 - 145,901,127 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRD8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12340,808,706 - 40,848,696 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2340,827,739 - 40,849,030 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603437,041,518 - 37,063,390 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brd8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474330,961,646 - 30,994,559 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474330,950,790 - 30,994,655 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Brd8
100 total Variants

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:36
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000048752
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2301410Bp317Blood pressure QTL 3170.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194427326548295Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat

1 to 10 of 33 rows
BE107954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21826,206,274 - 26,206,455 (+)MAPPERmRatBN7.2
Rnor_6.01827,400,319 - 27,400,499NCBIRnor6.0
Rnor_5.01827,113,691 - 27,113,871UniSTSRnor5.0
RGSC_v3.41827,075,618 - 27,075,798UniSTSRGSC3.4
Celera1825,944,090 - 25,944,270UniSTS
RH 3.4 Map18367.2UniSTS
Cytogenetic Map18p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 23 of 23 rows
RefSeq Transcripts NM_001008509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB180485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 23 of 23 rows

Ensembl Acc Id: ENSRNOT00000034385   ⟹   ENSRNOP00000033259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,181,732 - 26,229,884 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000048752   ⟹   ENSRNOP00000050917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,910 - 26,229,878 (-)Ensembl
Rnor_6.0 Ensembl1827,398,940 - 27,419,281 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087968   ⟹   ENSRNOP00000069953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,896 - 26,229,397 (-)Ensembl
Rnor_6.0 Ensembl1827,398,688 - 27,424,090 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101754   ⟹   ENSRNOP00000095490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,896 - 26,226,150 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106891   ⟹   ENSRNOP00000095492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,205,081 - 26,229,878 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115227   ⟹   ENSRNOP00000076361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,892 - 26,226,150 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118939   ⟹   ENSRNOP00000076647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,896 - 26,220,245 (-)Ensembl
RefSeq Acc Id: NM_001008509   ⟹   NP_001008509
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,499,373 (-)NCBI
mRatBN7.21826,204,892 - 26,225,244 (-)NCBI
Rnor_6.01827,398,936 - 27,419,287 (-)NCBI
Rnor_5.01827,089,007 - 27,137,524 (-)NCBI
RGSC_v3.41827,074,235 - 27,094,586 (-)RGD
Celera1825,942,707 - 25,963,058 (-)RGD
Sequence:
RefSeq Acc Id: NM_001414410   ⟹   NP_001401339
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,006 (-)NCBI
mRatBN7.21826,204,892 - 26,229,878 (-)NCBI
RefSeq Acc Id: XM_006254564   ⟹   XP_006254626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
mRatBN7.21826,204,892 - 26,229,999 (-)NCBI
Rnor_6.01827,398,936 - 27,423,989 (-)NCBI
Rnor_5.01827,089,007 - 27,137,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600912   ⟹   XP_017456401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
mRatBN7.21826,204,892 - 26,229,999 (-)NCBI
Rnor_6.01827,397,929 - 27,423,989 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096725   ⟹   XP_038952653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
mRatBN7.21826,204,892 - 26,229,999 (-)NCBI
RefSeq Acc Id: XM_063277223   ⟹   XP_063133293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277224   ⟹   XP_063133294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277225   ⟹   XP_063133295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,504,106 (-)NCBI
RefSeq Acc Id: XM_063277226   ⟹   XP_063133296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277227   ⟹   XP_063133297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277228   ⟹   XP_063133298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277229   ⟹   XP_063133299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277230   ⟹   XP_063133300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,484,219 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277231   ⟹   XP_063133301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,484,203 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277232   ⟹   XP_063133302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,484,219 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277233   ⟹   XP_063133303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,484,665 (-)NCBI
RefSeq Acc Id: XM_063277234   ⟹   XP_063133304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,485,461 (-)NCBI
1 to 30 of 35 rows
Protein RefSeqs NP_001008509 (Get FASTA)   NCBI Sequence Viewer  
  NP_001401339 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254626 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456401 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952653 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133293 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133294 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133295 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133296 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133297 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133298 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133299 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133300 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133301 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133302 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133303 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133304 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAD72893 (Get FASTA)   NCBI Sequence Viewer  
  EDL76231 (Get FASTA)   NCBI Sequence Viewer  
  EDL76232 (Get FASTA)   NCBI Sequence Viewer  
  EDL76233 (Get FASTA)   NCBI Sequence Viewer  
  EDL76234 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033259
  ENSRNOP00000033259.6
  ENSRNOP00000050917
  ENSRNOP00000050917.3
  ENSRNOP00000069953
  ENSRNOP00000069953.2
  ENSRNOP00000076361.1
  ENSRNOP00000076647
1 to 30 of 35 rows
1 to 5 of 24 rows
1 to 5 of 24 rows
RefSeq Acc Id: NP_001008509   ⟸   NM_001008509
- Peptide Label: isoform 2
- UniProtKB: Q5TLG7 (UniProtKB/TrEMBL),   A0A8I6ATL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254626   ⟸   XM_006254564
- Peptide Label: isoform X8
- UniProtKB: A0A0G2JWN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456401   ⟸   XM_017600912
- Peptide Label: isoform X9
- UniProtKB: A0A0G2JWN9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069953   ⟸   ENSRNOT00000087968
Ensembl Acc Id: ENSRNOP00000050917   ⟸   ENSRNOT00000048752
Bromo

Name Modeler Protein Id AA Range Protein Structure
AF-F1M858-F1-model_v2 AlphaFold F1M858 1-272 view protein structure
AF-E9PTN1-F1-model_v2 AlphaFold E9PTN1 1-957 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700696
Promoter ID:EPDNEW_R11219
Type:multiple initiation site
Name:Brd8_1
Description:bromodomain containing 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01827,423,912 - 27,423,972EPDNEW


1 to 40 of 42 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-7953 BioCyc
Ensembl Genes ENSRNOG00000020340 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034385 ENTREZGENE
  ENSRNOT00000034385.6 UniProtKB/TrEMBL
  ENSRNOT00000048752 ENTREZGENE
  ENSRNOT00000048752.4 UniProtKB/TrEMBL
  ENSRNOT00000087968 ENTREZGENE
  ENSRNOT00000087968.2 UniProtKB/TrEMBL
  ENSRNOT00000101754 ENTREZGENE
  ENSRNOT00000101754.1 UniProtKB/TrEMBL
  ENSRNOT00000106891 ENTREZGENE
  ENSRNOT00000106891.1 UniProtKB/TrEMBL
  ENSRNOT00000115227.1 UniProtKB/TrEMBL
  ENSRNOT00000118939 ENTREZGENE
  ENSRNOT00000118939.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
InterPro Brd8_Bromo_dom UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
KEGG Report rno:291691 UniProtKB/TrEMBL
NCBI Gene 291691 ENTREZGENE
PANTHER BROMODOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
  BROMODOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
PhenoGen Brd8 PhenoGen
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020340 RatGTEx
SMART BROMO UniProtKB/TrEMBL
Superfamily-SCOP Bromodomain UniProtKB/TrEMBL
UniProt A0A0G2JWN9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5XUT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y6W9_RAT UniProtKB/TrEMBL
  A0A8I6AR97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATL0 ENTREZGENE, UniProtKB/TrEMBL
  A6J2U9_RAT UniProtKB/TrEMBL
  A6J2V0_RAT UniProtKB/TrEMBL
  A6J2V1_RAT UniProtKB/TrEMBL
  A6J2V2_RAT UniProtKB/TrEMBL
  E9PTN1 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 42 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Brd8  bromodomain containing 8  Brd8_predicted  bromodomain containing 8 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Brd8_predicted  bromodomain containing 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED