Brd8 (bromodomain containing 8) - Rat Genome Database

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Gene: Brd8 (bromodomain containing 8) Rattus norvegicus
Analyze
Symbol: Brd8
Name: bromodomain containing 8
RGD ID: 1307003
Description: Predicted to enable nuclear receptor coactivator activity and nuclear thyroid hormone receptor binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of NuA4 histone acetyltransferase complex; Swr1 complex; and nucleosome. Biomarker of colorectal adenocarcinoma. Orthologous to human BRD8 (bromodomain containing 8); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; methapyrilene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bromodomain-containing protein 8; LOC291691; p120
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81826,455,824 - 26,504,106 (-)NCBIGRCr8
mRatBN7.21826,204,892 - 26,229,999 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,181,732 - 26,229,884 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,332,275 - 26,352,626 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,095,888 - 27,116,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01826,430,791 - 26,451,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01827,375,645 - 27,423,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1827,398,688 - 27,424,090 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,089,007 - 27,137,524 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,074,235 - 27,094,586 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11827,100,884 - 27,121,232 (-)NCBI
Celera1825,942,707 - 25,963,058 (-)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
5. The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics. Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.
6. BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy. Yamada HY and Rao CV, Int J Oncol. 2009 Nov;35(5):1101-9.
7. Co-activator p120 is increased by gonadotropins in the rat ovary and enhances progesterone receptor activity. Yoshino M, etal., Reprod Biol Endocrinol. 2006 Oct 3;4:50.
Additional References at PubMed
PMID:14966270   PMID:22082260   PMID:24463511   PMID:33173987  


Genomics

Comparative Map Data
Brd8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81826,455,824 - 26,504,106 (-)NCBIGRCr8
mRatBN7.21826,204,892 - 26,229,999 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,181,732 - 26,229,884 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,332,275 - 26,352,626 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,095,888 - 27,116,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01826,430,791 - 26,451,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01827,375,645 - 27,423,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1827,398,688 - 27,424,090 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,089,007 - 27,137,524 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,074,235 - 27,094,586 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11827,100,884 - 27,121,232 (-)NCBI
Celera1825,942,707 - 25,963,058 (-)NCBICelera
Cytogenetic Map18p12NCBI
BRD8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385138,139,770 - 138,178,630 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5138,139,770 - 138,178,953 (-)EnsemblGRCh38hg38GRCh38
GRCh375137,475,459 - 137,514,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365137,503,358 - 137,542,257 (-)NCBINCBI36Build 36hg18NCBI36
Celera5133,596,763 - 133,635,647 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5132,666,482 - 132,705,356 (-)NCBIHuRef
CHM1_15136,908,168 - 136,946,981 (-)NCBICHM1_1
T2T-CHM13v2.05138,666,102 - 138,704,922 (-)NCBIT2T-CHM13v2.0
Brd8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391834,731,668 - 34,757,916 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1834,731,668 - 34,757,654 (-)EnsemblGRCm39 Ensembl
GRCm381834,598,611 - 34,624,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1834,598,615 - 34,624,601 (-)EnsemblGRCm38mm10GRCm38
MGSCv371834,758,269 - 34,784,464 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361834,723,416 - 34,749,611 (-)NCBIMGSCv36mm8
Celera1835,051,227 - 35,077,223 (-)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.69NCBI
Brd8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554182,232,842 - 2,275,875 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554182,232,853 - 2,275,812 (+)NCBIChiLan1.0ChiLan1.0
BRD8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24133,413,615 - 133,452,773 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15131,553,168 - 131,592,326 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05133,535,321 - 133,557,304 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15139,652,112 - 139,690,468 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5139,652,112 - 139,690,468 (-)Ensemblpanpan1.1panPan2
BRD8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11125,793,375 - 25,825,868 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1125,793,668 - 25,825,726 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1124,559,631 - 24,592,299 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01126,645,970 - 26,678,830 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1126,645,978 - 26,678,526 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11125,353,288 - 25,385,951 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01125,176,899 - 25,208,532 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01125,840,328 - 25,872,995 (-)NCBIUU_Cfam_GSD_1.0
Brd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213154,249,563 - 154,292,389 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365317,333,907 - 7,362,114 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365317,333,974 - 7,361,855 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRD8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2140,168,636 - 140,202,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12140,182,195 - 140,202,247 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22145,866,443 - 145,901,127 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRD8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12340,808,706 - 40,848,696 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2340,827,739 - 40,849,030 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603437,041,518 - 37,063,390 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brd8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474330,961,646 - 30,994,559 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474330,950,790 - 30,994,655 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:36
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000048752
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301410Bp317Blood pressure QTL 3170.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181221923726822399Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18706572852065728Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)182201556261600538Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181564228031610627Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181221668431644508Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18706572852065728Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18706572852065728Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18706572852065728Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181522610142690662Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18546045542690191Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181221668431644508Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228031610627Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18144930869Rat
12904680Bw189Body weight QTL 1890.019body mass (VT:0001259)body weight (CMO:0000012)181221923726822399Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181206648257066482Rat
12904693Am20Aortic mass QTL 200.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)181221923726822399Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
12904695Kidm73Kidney mass QTL 730.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)181221923726822399Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18381190230809809Rat
12904689Cm128Cardiac mass QTL 1280.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)181221923726822399Rat
12904690Cm129Cardiac mass QTL 1290.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)181221923726822399Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134566578Rat
12904691Cm130Cardiac mass QTL 1300.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)181221923726822399Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18448264849482648Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
11565454Kidm59Kidney mass QTL 590.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)18706572852065728Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134566578Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)18430735449307354Rat

Markers in Region
BE107954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21826,206,274 - 26,206,455 (+)MAPPERmRatBN7.2
Rnor_6.01827,400,319 - 27,400,499NCBIRnor6.0
Rnor_5.01827,113,691 - 27,113,871UniSTSRnor5.0
RGSC_v3.41827,075,618 - 27,075,798UniSTSRGSC3.4
Celera1825,944,090 - 25,944,270UniSTS
RH 3.4 Map18367.2UniSTS
Cytogenetic Map18p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001008509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB180485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000034385   ⟹   ENSRNOP00000033259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,181,732 - 26,229,884 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000048752   ⟹   ENSRNOP00000050917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,910 - 26,229,878 (-)Ensembl
Rnor_6.0 Ensembl1827,398,940 - 27,419,281 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087968   ⟹   ENSRNOP00000069953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,896 - 26,229,397 (-)Ensembl
Rnor_6.0 Ensembl1827,398,688 - 27,424,090 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101754   ⟹   ENSRNOP00000095490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,896 - 26,226,150 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106891   ⟹   ENSRNOP00000095492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,205,081 - 26,229,878 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115227   ⟹   ENSRNOP00000076361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,892 - 26,226,150 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118939   ⟹   ENSRNOP00000076647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,204,896 - 26,220,245 (-)Ensembl
RefSeq Acc Id: NM_001008509   ⟹   NP_001008509
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,499,373 (-)NCBI
mRatBN7.21826,204,892 - 26,225,244 (-)NCBI
Rnor_6.01827,398,936 - 27,419,287 (-)NCBI
Rnor_5.01827,089,007 - 27,137,524 (-)NCBI
RGSC_v3.41827,074,235 - 27,094,586 (-)RGD
Celera1825,942,707 - 25,963,058 (-)RGD
Sequence:
RefSeq Acc Id: NM_001414410   ⟹   NP_001401339
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,006 (-)NCBI
mRatBN7.21826,204,892 - 26,229,878 (-)NCBI
RefSeq Acc Id: XM_006254564   ⟹   XP_006254626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
mRatBN7.21826,204,892 - 26,229,999 (-)NCBI
Rnor_6.01827,398,936 - 27,423,989 (-)NCBI
Rnor_5.01827,089,007 - 27,137,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600912   ⟹   XP_017456401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
mRatBN7.21826,204,892 - 26,229,999 (-)NCBI
Rnor_6.01827,397,929 - 27,423,989 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096725   ⟹   XP_038952653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
mRatBN7.21826,204,892 - 26,229,999 (-)NCBI
RefSeq Acc Id: XM_063277223   ⟹   XP_063133293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277224   ⟹   XP_063133294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277225   ⟹   XP_063133295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,504,106 (-)NCBI
RefSeq Acc Id: XM_063277226   ⟹   XP_063133296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277227   ⟹   XP_063133297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277228   ⟹   XP_063133298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277229   ⟹   XP_063133299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,479,022 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277230   ⟹   XP_063133300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,484,219 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277231   ⟹   XP_063133301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,484,203 - 26,500,055 (-)NCBI
RefSeq Acc Id: XM_063277232   ⟹   XP_063133302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,484,219 - 26,504,014 (-)NCBI
RefSeq Acc Id: XM_063277233   ⟹   XP_063133303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,484,665 (-)NCBI
RefSeq Acc Id: XM_063277234   ⟹   XP_063133304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,455,824 - 26,485,461 (-)NCBI
RefSeq Acc Id: NP_001008509   ⟸   NM_001008509
- Peptide Label: isoform 2
- UniProtKB: Q5TLG7 (UniProtKB/TrEMBL),   A0A8I6ATL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254626   ⟸   XM_006254564
- Peptide Label: isoform X8
- UniProtKB: A0A0G2JWN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456401   ⟸   XM_017600912
- Peptide Label: isoform X9
- UniProtKB: A0A0G2JWN9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069953   ⟸   ENSRNOT00000087968
Ensembl Acc Id: ENSRNOP00000050917   ⟸   ENSRNOT00000048752
RefSeq Acc Id: XP_038952653   ⟸   XM_039096725
- Peptide Label: isoform X5
- UniProtKB: E9PTN1 (UniProtKB/TrEMBL),   A0A0G2JWN9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076361   ⟸   ENSRNOT00000115227
Ensembl Acc Id: ENSRNOP00000095490   ⟸   ENSRNOT00000101754
Ensembl Acc Id: ENSRNOP00000076647   ⟸   ENSRNOT00000118939
Ensembl Acc Id: ENSRNOP00000095492   ⟸   ENSRNOT00000106891
Ensembl Acc Id: ENSRNOP00000033259   ⟸   ENSRNOT00000034385
RefSeq Acc Id: NP_001401339   ⟸   NM_001414410
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JWN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133295   ⟸   XM_063277225
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063133294   ⟸   XM_063277224
- Peptide Label: isoform X2
- UniProtKB: F1M858 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133293   ⟸   XM_063277223
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133304   ⟸   XM_063277234
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063133303   ⟸   XM_063277233
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063133299   ⟸   XM_063277229
- Peptide Label: isoform X10
- UniProtKB: A0A0G2JWN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133298   ⟸   XM_063277228
- Peptide Label: isoform X7
- UniProtKB: A0A0G2JWN9 (UniProtKB/TrEMBL),   A0A8I6AR97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133297   ⟸   XM_063277227
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ATL0 (UniProtKB/TrEMBL),   A0A8I5XUT9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133296   ⟸   XM_063277226
- Peptide Label: isoform X4
- UniProtKB: A0A8I6ATL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133301   ⟸   XM_063277231
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063133302   ⟸   XM_063277232
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063133300   ⟸   XM_063277230
- Peptide Label: isoform X11
Protein Domains
Bromo

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M858-F1-model_v2 AlphaFold F1M858 1-272 view protein structure
AF-E9PTN1-F1-model_v2 AlphaFold E9PTN1 1-957 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700696
Promoter ID:EPDNEW_R11219
Type:multiple initiation site
Name:Brd8_1
Description:bromodomain containing 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01827,423,912 - 27,423,972EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307003 AgrOrtholog
BioCyc Gene G2FUF-7953 BioCyc
Ensembl Genes ENSRNOG00000020340 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034385.6 UniProtKB/TrEMBL
  ENSRNOT00000048752.4 UniProtKB/TrEMBL
  ENSRNOT00000087968.2 UniProtKB/TrEMBL
  ENSRNOT00000101754.1 UniProtKB/TrEMBL
  ENSRNOT00000106891.1 UniProtKB/TrEMBL
  ENSRNOT00000115227.1 UniProtKB/TrEMBL
  ENSRNOT00000118939.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
InterPro Brd8_Bromo_dom UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
KEGG Report rno:291691 UniProtKB/TrEMBL
NCBI Gene 291691 ENTREZGENE
PANTHER BROMODOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
  BROMODOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
PhenoGen Brd8 PhenoGen
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020340 RatGTEx
SMART BROMO UniProtKB/TrEMBL
Superfamily-SCOP Bromodomain UniProtKB/TrEMBL
UniProt A0A0G2JWN9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5XUT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y6W9_RAT UniProtKB/TrEMBL
  A0A8I6AR97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATL0 ENTREZGENE, UniProtKB/TrEMBL
  A6J2U9_RAT UniProtKB/TrEMBL
  A6J2V0_RAT UniProtKB/TrEMBL
  A6J2V1_RAT UniProtKB/TrEMBL
  A6J2V2_RAT UniProtKB/TrEMBL
  E9PTN1 ENTREZGENE, UniProtKB/TrEMBL
  F1M858 ENTREZGENE, UniProtKB/TrEMBL
  Q5TLG7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Brd8  bromodomain containing 8  Brd8_predicted  bromodomain containing 8 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Brd8_predicted  bromodomain containing 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED