Gene: Flrt3 (fibronectin leucine rich transmembrane protein 3) Rattus norvegicus
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Symbol: Flrt3
Name: fibronectin leucine rich transmembrane protein 3
Description: ENCODES a protein that exhibits chemorepellent activity (ortholog); fibroblast growth factor receptor binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN axon guidance; neuron projection development; neuron projection extension; ASSOCIATED WITH hypogonadotropic hypogonadism 21 with or without anosmia (ortholog); hypogonadotropic hypogonadism 7 with or without anosmia (ortholog); Spontaneous Abortion (ortholog); FOUND IN axon terminus; integral component of plasma membrane; integral component of postsynaptic membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; amitriptyline
AGR Description: Predicted to have chemorepellent activity, fibroblast growth factor receptor binding activity, and protein homodimerization activity; involved in cell morphogenesis, response to axon injury, and synapse organization; localizes to the axon terminus, integral component of postsynaptic membrane, and postsynaptic density; predicted to colocalize with the focal adhesion; orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3).
Merged Description: Predicted to have chemorepellent activity, fibroblast growth factor receptor binding activity, and protein homodimerization activity; involved in cell morphogenesis, response to axon injury, and synapse organization; localizes to the axon terminus, integral component of postsynaptic membrane, and postsynaptic density; predicted to colocalize with the focal adhesion; orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; amitriptyline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: fibronectin-like domain-containing leucine-rich transmembrane protein 3; leucine-rich repeat transmembrane protein FLRT3; LOC366205; RGD1566005; similar to fibronectin leucine rich transmembrane protein 3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03134,684,446 - 134,696,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03141,134,890 - 141,147,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,922,726 - 128,934,866 (-)NCBIRGSC3.4rn4RGSC3.4
Celera3126,621,420 - 126,633,560 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Flrt3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1566005
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.