Sh3pxd2a (SH3 and PX domains 2A) - Rat Genome Database

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Gene: Sh3pxd2a (SH3 and PX domains 2A) Rattus norvegicus
Analyze
Symbol: Sh3pxd2a
Name: SH3 and PX domains 2A
RGD ID: 1311185
Description: Predicted to enable several functions, including phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and superoxide-generating NADPH oxidase activator activity. Predicted to be involved in osteoclast fusion and superoxide anion generation. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in podosome. Predicted to be active in cytoplasm. Orthologous to human SH3PXD2A (SH3 and PX domains 2A); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC309460; SH3 and PX domain-containing protein 2A; SH3 multiple domains 1; Sh3md1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81256,094,991 - 256,301,120 (-)NCBIGRCr8
mRatBN7.21246,153,660 - 246,359,806 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,160,502 - 246,360,166 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1254,286,899 - 254,444,343 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01260,980,787 - 261,138,068 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01253,629,151 - 253,786,369 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01267,039,654 - 267,245,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1267,046,361 - 267,245,636 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01274,470,628 - 274,678,690 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41252,601,140 - 252,796,776 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11252,865,756 - 253,103,796 (-)NCBI
Celera1241,931,038 - 242,085,237 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
chrysene  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dicrotophos  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12615925   PMID:18417249   PMID:19755709   PMID:19755710   PMID:20609497   PMID:22584907   PMID:25931508   PMID:27996060  


Genomics

Comparative Map Data
Sh3pxd2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81256,094,991 - 256,301,120 (-)NCBIGRCr8
mRatBN7.21246,153,660 - 246,359,806 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,160,502 - 246,360,166 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1254,286,899 - 254,444,343 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01260,980,787 - 261,138,068 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01253,629,151 - 253,786,369 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01267,039,654 - 267,245,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1267,046,361 - 267,245,636 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01274,470,628 - 274,678,690 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41252,601,140 - 252,796,776 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11252,865,756 - 253,103,796 (-)NCBI
Celera1241,931,038 - 242,085,237 (-)NCBICelera
Cytogenetic Map1q54NCBI
SH3PXD2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810103,594,027 - 103,855,576 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10103,594,027 - 103,855,584 (-)EnsemblGRCh38hg38GRCh38
GRCh3710105,353,784 - 105,615,334 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610105,343,774 - 105,605,154 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410105,343,773 - 105,605,154NCBI
Celera1099,093,721 - 99,355,050 (-)NCBICelera
Cytogenetic Map10q24.33NCBI
HuRef1098,984,423 - 99,246,081 (-)NCBIHuRef
CHM1_110105,637,905 - 105,898,918 (-)NCBICHM1_1
T2T-CHM13v2.010104,481,342 - 104,742,826 (-)NCBIT2T-CHM13v2.0
Sh3pxd2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391947,248,613 - 47,453,053 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1947,248,613 - 47,452,840 (-)EnsemblGRCm39 Ensembl
GRCm381947,260,174 - 47,464,612 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1947,260,174 - 47,464,401 (-)EnsemblGRCm38mm10GRCm38
MGSCv371947,334,664 - 47,538,901 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361947,320,224 - 47,517,722 (-)NCBIMGSCv36mm8
Celera1948,016,878 - 48,203,451 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1939.45NCBI
Sh3pxd2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554856,811,844 - 7,009,432 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554856,811,857 - 7,008,011 (+)NCBIChiLan1.0ChiLan1.0
SH3PXD2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28115,480,543 - 115,742,157 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110115,477,065 - 115,747,464 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010100,193,961 - 100,455,200 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110103,655,409 - 103,729,572 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10103,663,163 - 103,861,437 (-)Ensemblpanpan1.1panPan2
SH3PXD2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12815,936,927 - 16,165,537 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2815,943,097 - 16,117,710 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2816,108,640 - 16,342,907 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02816,413,263 - 16,648,091 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2816,417,811 - 16,648,071 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12815,961,861 - 16,196,960 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02815,989,976 - 16,225,123 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02816,128,444 - 16,363,617 (-)NCBIUU_Cfam_GSD_1.0
Sh3pxd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721330,740,484 - 30,911,584 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366002,343,658 - 2,509,612 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366002,343,709 - 2,513,497 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3PXD2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14114,519,928 - 114,777,238 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114114,515,459 - 114,777,251 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214124,396,943 - 124,484,440 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH3PXD2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1996,645,955 - 96,898,749 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604857,760,430 - 58,016,287 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3pxd2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248312,786,950 - 2,973,702 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248312,779,899 - 2,973,576 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sh3pxd2a
1248 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:67
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000027574
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233190394258625266Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
631836Stl31Serum triglyceride level QTL 314.640.00000487blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1238699859259647894Rat
1598839Rf56Renal function QTL 56renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1245907761257976495Rat

Markers in Region
D1Rat454  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21246,190,345 - 246,190,573 (+)MAPPERmRatBN7.2
Rnor_6.01267,076,330 - 267,076,557NCBIRnor6.0
Rnor_5.01274,507,310 - 274,507,537UniSTSRnor5.0
RGSC_v3.41252,630,980 - 252,631,208RGDRGSC3.4
RGSC_v3.41252,630,981 - 252,631,208UniSTSRGSC3.4
RGSC_v3.11252,895,553 - 252,895,781RGD
Celera1241,960,889 - 241,961,116UniSTS
SHRSP x BN Map1139.09RGD
SHRSP x BN Map1139.09UniSTS
Cytogenetic Map1q54UniSTS
D1Got239  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21246,354,238 - 246,354,356 (+)MAPPERmRatBN7.2
Rnor_6.01267,240,424 - 267,240,541NCBIRnor6.0
Rnor_5.01274,673,222 - 274,673,339UniSTSRnor5.0
RGSC_v3.41252,834,114 - 252,834,232RGDRGSC3.4
RGSC_v3.41252,834,115 - 252,834,232UniSTSRGSC3.4
RGSC_v3.11253,098,688 - 253,098,805RGD
Celera1242,121,646 - 242,121,763UniSTS
RH 3.4 Map11635.1UniSTS
RH 3.4 Map11635.1RGD
RH 2.0 Map11244.4RGD
Cytogenetic Map1q54UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 40 10 4 13 4 2 4 55 23 33 11 2
Low 1 3 47 37 6 37 6 7 19 12 8 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000027574   ⟹   ENSRNOP00000027574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,160,502 - 246,319,316 (-)Ensembl
Rnor_6.0 Ensembl1267,046,490 - 267,203,986 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082799   ⟹   ENSRNOP00000070182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,160,502 - 246,289,101 (-)Ensembl
Rnor_6.0 Ensembl1267,046,361 - 267,245,636 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099914   ⟹   ENSRNOP00000078462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,160,502 - 246,360,166 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100437   ⟹   ENSRNOP00000090159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,160,502 - 246,360,166 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103789   ⟹   ENSRNOP00000095118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,160,502 - 246,309,813 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118210   ⟹   ENSRNOP00000095611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,160,502 - 246,360,166 (-)Ensembl
RefSeq Acc Id: NM_001107606   ⟹   NP_001101076
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,094,991 - 256,300,967 (-)NCBI
mRatBN7.21246,153,660 - 246,359,655 (-)NCBI
Rnor_6.01267,046,490 - 267,203,986 (-)NCBI
Rnor_5.01274,470,628 - 274,678,690 (-)NCBI
RGSC_v3.41252,601,140 - 252,796,776 (-)RGD
Celera1241,931,038 - 242,085,237 (-)RGD
Sequence:
RefSeq Acc Id: NM_001415946   ⟹   NP_001402875
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,094,991 - 256,300,967 (-)NCBI
mRatBN7.21246,153,660 - 246,359,655 (-)NCBI
RefSeq Acc Id: XM_006231514   ⟹   XP_006231576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,094,996 - 256,301,120 (-)NCBI
mRatBN7.21246,153,660 - 246,359,806 (-)NCBI
Rnor_6.01267,039,654 - 267,245,868 (-)NCBI
Rnor_5.01274,470,628 - 274,678,690 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039080588   ⟹   XP_038936516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,094,996 - 256,292,139 (-)NCBI
mRatBN7.21246,153,660 - 246,350,895 (-)NCBI
RefSeq Acc Id: NP_001101076   ⟸   NM_001107606
- Peptide Label: isoform 1
- UniProtKB: A0A8I6G2U9 (UniProtKB/TrEMBL),   D3ZMW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231576   ⟸   XM_006231514
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AP29 (UniProtKB/TrEMBL),   D3ZMW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070182   ⟸   ENSRNOT00000082799
RefSeq Acc Id: ENSRNOP00000027574   ⟸   ENSRNOT00000027574
RefSeq Acc Id: XP_038936516   ⟸   XM_039080588
- Peptide Label: isoform X2
- UniProtKB: A6JHQ5 (UniProtKB/TrEMBL),   A0A0G2JX92 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000095118   ⟸   ENSRNOT00000103789
RefSeq Acc Id: ENSRNOP00000095611   ⟸   ENSRNOT00000118210
RefSeq Acc Id: ENSRNOP00000090159   ⟸   ENSRNOT00000100437
RefSeq Acc Id: ENSRNOP00000078462   ⟸   ENSRNOT00000099914
RefSeq Acc Id: NP_001402875   ⟸   NM_001415946
- Peptide Label: isoform 2
- UniProtKB: A0A8I6AD93 (UniProtKB/TrEMBL),   D3ZMW5 (UniProtKB/TrEMBL)
Protein Domains
PX   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JX92-F1-model_v2 AlphaFold A0A0G2JX92 1-1109 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311185 AgrOrtholog
BioCyc Gene G2FUF-55485 BioCyc
Ensembl Genes ENSRNOG00000020353 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027574.4 UniProtKB/TrEMBL
  ENSRNOT00000082799.2 UniProtKB/TrEMBL
  ENSRNOT00000099914 ENTREZGENE
  ENSRNOT00000099914.1 UniProtKB/TrEMBL
  ENSRNOT00000100437 ENTREZGENE
  ENSRNOT00000100437.1 UniProtKB/TrEMBL
  ENSRNOT00000103789.1 UniProtKB/TrEMBL
  ENSRNOT00000118210.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro IPR001683 UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SH3PXD2_PX UniProtKB/TrEMBL
  SH3PXD2A_SH3_1 UniProtKB/TrEMBL
  SH3PXD2A_SH3_2 UniProtKB/TrEMBL
  SH3PXD2A_SH3_3 UniProtKB/TrEMBL
  SH3PXD2A_SH3_4 UniProtKB/TrEMBL
  SH3PXD2A_SH3_5 UniProtKB/TrEMBL
KEGG Report rno:309460 UniProtKB/TrEMBL
NCBI Gene 309460 ENTREZGENE
PANTHER PTHR15706:SF22 UniProtKB/TrEMBL
  SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B UniProtKB/TrEMBL
  SH3 MULTIPLE DOMAIN UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PhenoGen Sh3pxd2a PhenoGen
PROSITE PS50195 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020353 RatGTEx
SMART SH3 UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP 64268 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
UniProt A0A0G2JX92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AD93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKV6_RAT UniProtKB/TrEMBL
  A0A8I6AP29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G2U9 ENTREZGENE, UniProtKB/TrEMBL
  A6JHQ5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZMW5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Sh3pxd2a  SH3 and PX domains 2A   Sh3pxd2a_predicted  SH3 and PX domains 2A (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Sh3pxd2a_predicted  SH3 and PX domains 2A (predicted)  Sh3md1_predicted  SH3 multiple domains 1 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Sh3md1_predicted  SH3 multiple domains 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED