Necap1 (NECAP endocytosis associated 1) - Rat Genome Database

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Gene: Necap1 (NECAP endocytosis associated 1) Rattus norvegicus
Analyze
Symbol: Necap1
Name: NECAP endocytosis associated 1
RGD ID: 1306053
Description: Involved in presynaptic endocytosis. Is active in presynapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 21. Orthologous to human NECAP1 (NECAP endocytosis associated 1); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adaptin ear-binding clathrin-associated protein; adaptin ear-binding coat-associated protein 1; LOC312694; MGC114570; NECAP endocytosis-associated protein 1; NECAP-1; RGD1306053; similar to RIKEN cDNA 1200016B17
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,775,890 - 157,790,992 (+)NCBIGRCr8
mRatBN7.24156,103,935 - 156,119,068 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4156,103,988 - 156,119,068 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4162,373,641 - 162,388,733 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04158,156,863 - 158,171,955 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04156,801,946 - 156,817,038 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04155,709,712 - 155,724,801 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,709,613 - 155,724,790 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,730,478 - 222,745,567 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44159,354,507 - 159,369,596 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14159,599,461 - 159,614,524 (+)NCBI
Celera4144,924,247 - 144,939,336 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization of the localization and function of NECAP 1 in neurons. Murshid A, etal., J Neurochem. 2006 Sep;98(6):1746-62. doi: 10.1111/j.1471-4159.2006.04066.x. Epub 2006 Jul 31.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The NECAP PHear domain increases clathrin accessory protein binding potential. Ritter B, etal., EMBO J. 2007 Sep 19;26(18):4066-77. Epub 2007 Aug 30.
8. NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis. Ritter B, etal., PLoS Biol. 2013 Oct;11(10):e1001670. doi: 10.1371/journal.pbio.1001670. Epub 2013 Oct 1.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14555962   PMID:15057822   PMID:15292237   PMID:16903783   PMID:22871113   PMID:29476059  


Genomics

Comparative Map Data
Necap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,775,890 - 157,790,992 (+)NCBIGRCr8
mRatBN7.24156,103,935 - 156,119,068 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4156,103,988 - 156,119,068 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4162,373,641 - 162,388,733 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04158,156,863 - 158,171,955 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04156,801,946 - 156,817,038 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04155,709,712 - 155,724,801 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,709,613 - 155,724,790 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,730,478 - 222,745,567 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44159,354,507 - 159,369,596 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14159,599,461 - 159,614,524 (+)NCBI
Celera4144,924,247 - 144,939,336 (+)NCBICelera
Cytogenetic Map4q42NCBI
NECAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,082,274 - 8,097,881 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,076,939 - 8,097,881 (+)EnsemblGRCh38hg38GRCh38
GRCh37128,234,870 - 8,250,477 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,989,001 - 8,141,634 (+)NCBINCBI36Build 36hg18NCBI36
Celera129,811,877 - 9,827,432 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef128,046,534 - 8,062,074 (+)NCBIHuRef
CHM1_1128,234,026 - 8,249,598 (+)NCBICHM1_1
T2T-CHM13v2.0128,095,874 - 8,111,478 (+)NCBIT2T-CHM13v2.0
Necap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396122,851,516 - 122,865,902 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6122,851,433 - 122,865,900 (+)EnsemblGRCm39 Ensembl
GRCm386122,874,557 - 122,888,943 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6122,874,474 - 122,888,941 (+)EnsemblGRCm38mm10GRCm38
MGSCv376122,824,575 - 122,838,959 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366122,840,176 - 122,854,560 (+)NCBIMGSCv36mm8
Celera6124,676,728 - 124,691,173 (+)NCBICelera
Cytogenetic Map6F2NCBI
cM Map657.96NCBI
Necap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554136,737,785 - 6,754,162 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554136,737,785 - 6,751,672 (+)NCBIChiLan1.0ChiLan1.0
NECAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21013,635,763 - 13,653,693 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11213,632,524 - 13,654,420 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,201,908 - 8,217,043 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,244,137 - 8,259,247 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl128,243,785 - 8,282,647 (+)Ensemblpanpan1.1panPan2
NECAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,460,545 - 37,472,512 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,460,607 - 37,507,052 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha279,143,445 - 9,155,412 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02737,814,521 - 37,826,493 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,814,508 - 37,864,273 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,689,204 - 37,701,156 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,730,473 - 37,742,640 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,630,216 - 8,642,197 (-)NCBIUU_Cfam_GSD_1.0
Necap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494599,188,170 - 99,200,553 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936892372,284 - 385,202 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936892372,743 - 385,127 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,122,335 - 63,139,664 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,122,280 - 63,135,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NECAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,155,432 - 8,170,873 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,154,976 - 8,171,025 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666089251,027 - 267,789 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Necap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248605,223,610 - 5,237,451 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248605,224,170 - 5,237,235 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Necap1
54 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:149
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000013272
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4148423102157580971Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
731178Oia7Oil induced arthritis QTL 70.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4156050654157232313Rat

Markers in Region
AA998017  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24156,113,085 - 156,113,229 (+)MAPPERmRatBN7.2
Rnor_6.04155,718,820 - 155,718,963NCBIRnor6.0
Rnor_5.04222,739,586 - 222,739,729UniSTSRnor5.0
RGSC_v3.44159,363,615 - 159,363,758UniSTSRGSC3.4
Celera4144,933,355 - 144,933,498UniSTS
RH 3.4 Map41002.9UniSTS
Cytogenetic Map4q42UniSTS
RH141222  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24156,118,668 - 156,118,859 (+)MAPPERmRatBN7.2
Rnor_6.04155,724,402 - 155,724,592NCBIRnor6.0
Rnor_5.04222,745,168 - 222,745,358UniSTSRnor5.0
RGSC_v3.44159,369,197 - 159,369,387UniSTSRGSC3.4
Celera4144,938,937 - 144,939,127UniSTS
RH 3.4 Map41002.1UniSTS
Cytogenetic Map4q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 2 2 74 35 39 11 2
Low 6 6 9 2 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000013272   ⟹   ENSRNOP00000013272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4156,103,988 - 156,119,068 (+)Ensembl
Rnor_6.0 Ensembl4155,709,613 - 155,724,790 (+)Ensembl
RefSeq Acc Id: NM_001029919   ⟹   NP_001025090
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84157,775,903 - 157,790,992 (+)NCBI
mRatBN7.24156,103,978 - 156,119,068 (+)NCBI
Rnor_6.04155,709,712 - 155,724,801 (+)NCBI
Rnor_5.04222,730,478 - 222,745,567 (+)NCBI
RGSC_v3.44159,354,507 - 159,369,596 (+)RGD
Celera4144,924,247 - 144,939,336 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237305   ⟹   XP_006237367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84157,775,890 - 157,790,911 (+)NCBI
mRatBN7.24156,103,959 - 156,119,068 (+)NCBI
Rnor_6.04155,709,736 - 155,724,801 (+)NCBI
Rnor_5.04222,730,478 - 222,745,567 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001025090 (Get FASTA)   NCBI Sequence Viewer  
  XP_006237367 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH97496 (Get FASTA)   NCBI Sequence Viewer  
  EDM01977 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013272
  ENSRNOP00000013272.6
  ENSRNOP00055015925
  ENSRNOP00060038441
  ENSRNOP00065047169
GenBank Protein P69682 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001025090   ⟸   NM_001029919
- UniProtKB: Q4QR67 (UniProtKB/Swiss-Prot),   P69682 (UniProtKB/Swiss-Prot),   A6ILG2 (UniProtKB/TrEMBL),   A0A8L2Q6N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237367   ⟸   XM_006237305
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q6N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013272   ⟸   ENSRNOT00000013272
Protein Domains
NECAP PHear

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P69682-F1-model_v2 AlphaFold P69682 1-277 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693373
Promoter ID:EPDNEW_R3898
Type:multiple initiation site
Name:Necap1_1
Description:NECAP endocytosis associated 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04155,709,719 - 155,709,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306053 AgrOrtholog
BioCyc Gene G2FUF-43139 BioCyc
Ensembl Genes ENSRNOG00000009236 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055011623 UniProtKB/Swiss-Prot
  ENSRNOG00060026675 UniProtKB/Swiss-Prot
  ENSRNOG00065033350 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013272.7 UniProtKB/TrEMBL
  ENSRNOT00055019747 UniProtKB/Swiss-Prot
  ENSRNOT00060046269 UniProtKB/Swiss-Prot
  ENSRNOT00065057328 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7461823 IMAGE-MGC_LOAD
InterPro NECAP_PHear UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:312694 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:114570 IMAGE-MGC_LOAD
NCBI Gene 312694 ENTREZGENE
PANTHER ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF1681 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Necap1 PhenoGen
RatGTEx ENSRNOG00000009236 RatGTEx
  ENSRNOG00055011623 RatGTEx
  ENSRNOG00060026675 RatGTEx
  ENSRNOG00065033350 RatGTEx
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2Q6N8 ENTREZGENE, UniProtKB/TrEMBL
  A6ILG2 ENTREZGENE, UniProtKB/TrEMBL
  NECP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q4QR67 ENTREZGENE
UniProt Secondary Q4QR67 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Necap1  NECAP endocytosis associated 1  RGD1306053  similar to RIKEN cDNA 1200016B17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1306053  similar to RIKEN cDNA 1200016B17  RGD1306053_predicted  similar to RIKEN cDNA 1200016B17 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1306053_predicted  similar to RIKEN cDNA 1200016B17 (predicted)  LOC312694_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC312694_predicted  similar to RIKEN cDNA 1200016B17 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL