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Gene: Spry2 (sprouty RTK signaling antagonist 2) Rattus norvegicus
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Symbol: Spry2
Name: sprouty RTK signaling antagonist 2
Description: Predicted to have protein kinase binding activity and protein serine/threonine kinase activator activity. Predicted to be involved in several processes, including lung development; regulation of protein phosphorylation; and regulation of signal transduction. Predicted to localize to several cellular components, including the cytoskeleton; cytosol; and nucleus. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human SPRY2 (sprouty RTK signaling antagonist 2); PARTICIPATES IN fibroblast growth factor signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC306141; sprouty 2; sprouty homolog 2; sprouty homolog 2 (Drosophila)
Orthologs:
Homo sapiens (human) : SPRY2 (sprouty RTK signaling antagonist 2)  HGNC  Alliance
Mus musculus (house mouse) : Spry2 (sprouty RTK signaling antagonist 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spry2 (sprouty RTK signaling antagonist 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRY2 (sprouty RTK signaling antagonist 2)
Canis lupus familiaris (dog) : SPRY2 (sprouty RTK signaling antagonist 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spry2 (sprouty RTK signaling antagonist 2)
Sus scrofa (pig) : SPRY2 (sprouty RTK signaling antagonist 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01590,172,769 - 90,177,823 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1590,172,975 - 90,175,802 (-)Ensembl
Rnor_5.01593,662,768 - 93,667,781 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41590,009,109 - 90,011,940 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11590,024,884 - 90,027,720 (-)NCBI
Celera1581,798,483 - 81,801,309 (-)NCBICelera
Cytogenetic Map15q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Spry2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311472
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.