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Gene: Aldh18a1 (aldehyde dehydrogenase 18 family, member A1) Rattus norvegicus
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Symbol: Aldh18a1
Name: aldehyde dehydrogenase 18 family, member A1
Description: Predicted to have glutamate 5-kinase activity; glutamate-5-semialdehyde dehydrogenase activity; and identical protein binding activity. Involved in response to temperature stimulus. Localizes to the mitochondrial membrane. Human ortholog(s) of this gene implicated in cataract; cutis laxa (multiple); enterocele; and hereditary spastic paraplegia (multiple). Orthologous to human ALDH18A1 (aldehyde dehydrogenase 18 family member A1); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: delta-1-pyrroline-5-carboxylate synthase; LOC361755; Pycs; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01259,641,673 - 259,674,521 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1259,641,676 - 259,674,425 (-)Ensembl
Rnor_6.0 Ensembl1259,057,402 - 259,089,642 (-)Ensembl
Rnor_5.01266,505,493 - 266,537,820 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01267,085,392 - 267,117,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41245,685,979 - 245,718,198 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11245,796,065 - 245,825,127 (-)NCBI
Celera1235,221,086 - 235,253,280 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Aldh18a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311431
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.