Aldh18a1 (aldehyde dehydrogenase 18 family member A1)

Gene: Aldh18a1 (aldehyde dehydrogenase 18 family member A1) Chinchilla lanigera

Analyze

Symbol:

Aldh18a1

Name:

aldehyde dehydrogenase 18 family member A1

RGD ID:

9054230

Description:

ENCODES a protein that exhibits glutamate 5-kinase activity (ortholog); glutamate-5-semialdehyde dehydrogenase activity (ortholog); identical protein binding (ortholog); INVOLVED IN citrulline biosynthetic process (ortholog); glutamate metabolic process (ortholog); ornithine biosynthetic process (ortholog); ASSOCIATED WITH agammaglobulinemia 4 (ortholog); Animal Disease Models (ortholog); autosomal dominant cutis laxa (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

aldehyde dehydrogenase 18 family, member A1; delta-1-pyrroline-5-carboxylate synthase

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955507	1,892,061 - 1,946,703 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955507	1,892,087 - 1,946,526 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

agammaglobulinemia 4 (ISO)

Animal Disease Models (ISO)

autosomal dominant cutis laxa (ISO)

autosomal dominant cutis laxa 3 (ISO)

Autosomal Recessive Cutis Laxa (ISO)

autosomal recessive cutis laxa type III (ISO)

autosomal recessive cutis laxa type IIIA (ISO)

cataract (ISO)

enterocele (ISO)

Fetal Growth Retardation (ISO)

genetic disease (ISO)

hereditary spastic paraplegia (ISO)

hereditary spastic paraplegia 5A (ISO)

hereditary spastic paraplegia 9A (ISO)

hereditary spastic paraplegia 9B (ISO)

intellectual disability (ISO)

lung adenocarcinoma (ISO)

Nervous System Malformations (ISO)

Neurocutaneous Syndromes (ISO)

spondyloepiphyseal dysplasia Stanescu type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

citrulline biosynthetic process (ISO)

glutamate metabolic process (ISO)

ornithine biosynthetic process (ISO)

proline biosynthetic process (ISO)

response to temperature stimulus (ISO)

Cellular Component

mitochondrial membrane (ISO)

mitochondrion (ISO)

Molecular Function

glutamate 5-kinase activity (ISO)

glutamate-5-semialdehyde dehydrogenase activity (ISO)

identical protein binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Aldh18a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955507	1,892,061 - 1,946,703 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955507	1,892,087 - 1,946,526 (-)	NCBI	ChiLan1.0	ChiLan1.0

ALDH18A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	95,605,941 - 95,656,711 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	95,605,941 - 95,656,711 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	97,365,698 - 97,416,468 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	97,355,676 - 97,406,557 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	97,355,691 - 97,406,372	NCBI
Celera	10	91,106,883 - 91,157,764 (-)	NCBI		Celera
Cytogenetic Map	10	q24.1	NCBI
HuRef	10	90,993,396 - 91,044,247 (-)	NCBI		HuRef
CHM1_1	10	97,647,547 - 97,698,414 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	96,485,079 - 96,535,811 (-)	NCBI		T2T-CHM13v2.0

Aldh18a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	40,538,701 - 40,576,907 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	40,538,701 - 40,576,907 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	40,550,257 - 40,588,463 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	40,550,257 - 40,588,463 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	40,624,747 - 40,662,953 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	40,603,568 - 40,641,680 (-)	NCBI		MGSCv36	mm8
Celera	19	41,354,703 - 41,390,340 (-)	NCBI		Celera
Cytogenetic Map	19	C3	NCBI
cM Map	19	34.25	NCBI

Aldh18a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	249,325,082 - 249,357,383 (-)	NCBI		GRCr8
mRatBN7.2	1	239,375,657 - 239,407,956 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	239,375,669 - 239,407,890 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	247,511,391 - 247,543,700 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	254,215,141 - 254,247,493 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	246,868,177 - 246,900,530 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	259,641,673 - 259,674,521 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	259,641,676 - 259,674,425 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	1	259,057,402 - 259,089,642 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	267,085,392 - 267,117,725 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	1	266,505,493 - 266,537,820 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	245,685,979 - 245,718,198 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	245,796,065 - 245,825,127 (-)	NCBI
Celera	1	235,221,086 - 235,253,280 (-)	NCBI		Celera
Cytogenetic Map	1	q54	NCBI

ALDH18A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	107,509,648 - 107,560,640 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	107,514,963 - 107,565,958 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	92,216,639 - 92,267,525 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	95,723,099 - 95,774,095 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	95,723,099 - 95,774,095 (-)	Ensembl	panpan1.1		panPan2

ALDH18A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	9,101,578 - 9,148,063 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	9,102,282 - 9,147,992 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	9,277,306 - 9,324,003 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	9,363,581 - 9,410,371 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	9,363,590 - 9,410,427 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	9,080,159 - 9,126,835 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	9,138,798 - 9,185,591 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	9,282,780 - 9,329,594 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101975532
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	37,740,140 - 37,762,024 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936636	3,760,326 - 3,801,073 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936636	3,779,259 - 3,800,846 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALDH18A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	107,170,689 - 107,221,215 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	107,174,062 - 107,221,373 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	116,807,918 - 116,855,192 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ALDH18A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	88,773,493 - 88,823,438 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	49,641,146 - 49,691,137 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aldh18a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	6,921,222 - 6,970,488 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	6,921,619 - 6,970,113 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005407547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005407548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013506238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01065573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01272098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000002596 ⟹ ENSCLAP00000002543

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955507	1,892,061 - 1,946,703 (-)	Ensembl

RefSeq Acc Id:

XM_005407547 ⟹ XP_005407604

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955507	1,892,087 - 1,946,419 (-)	NCBI

Sequence:

show sequence

AGACGGAAGAAAAGGGAGGCCGAGCGGGCGCCTGCATCATCCCGGCGTGGAGCGCGGCCGGGCG
GGTGGTGGCTGAGCGCGGGACGCAGGTATTGGATTAGTGACCACATCTCACCATGTTGAGTCAA
GTTTACCGCTCTGGGTTCCAGCCCTTCAACCATCGTGTTCTGCCTTGGGTCCAGTCCACAGCTG
TCTCCAGATCTTATCGTGGACAGCATTCAGCCATCAGACATGTTCGTTCTTGGAGCAACATCCC
CTTTATCACAGTACCCCTCAGTCGTGCCCATGGCAAGTCCTTTGCCCACCGAAGTGAGCTGAAG
CATGCCAAGAGGATTGTAGTGAAACTCGGCAGTGCTGTGGTGACCCGAGGAGATGAGTGTGGCC
TGGCATTGGGGCGCCTGGCATCTATTGTGGAGCAGGTATCCGTGCTACAAAATCAGGGCCGAGA
GATGATGCTGGTGACCAGTGGAGCTGTAGCCTTTGGCAAGCAGCGATTGCGCCATGAGATCCTT
CTGTCTCAAAGCGTGCGACAGGCCCTGCACTCAGGGCAGAACCAGCTGAAAGAGATGGCAATTC
CAGTCTTAGAGGCGCGAGCCTGTGCAGCTGCCGGACAGAGTGGGCTGATGGCCTTGTATGAAGC
CATGTTTACCCAGTATAGCATCTGTGCTGCCCAGATTTTGGTGACCAACCTGGATTTCCATGAT
GAGCAGAAACGCCGGAACCTCAATGGGACTCTTCATGAACTCCTTCGAATGAACATCGTCCCCA
TTGTCAACACAAATGATGCTGTTGTCCCCCCAGCTGAGCCCAACAGTGATCTGCAGGGGGTAAA
TGTTATTAGTGTTAAAGATAATGATAGTCTGGCTGCCCGCCTGGCTGTGGAAATGAAAACTGAC
CTCCTGATTGTTCTTTCAGATGTAGAAGGCCTCTTTGACAGCCCCCCAGGGTCAGATGATGCAA
AGCTCATTGATACATTTTATCCCGGTGATCAGCAGTCTGTAACATTTGGAACCAAGTCTAGAGT
GGGAATGGGAGGCATGGAAGCCAAGGTGAAAGCAGCGCTCTGGGCTTTACAAGGTGGCACTTCC
GTTGTTATTGCGAATGGAACCCACCCCAAGGTGTCTGGGCATGTCATCACAGACATCGTGGAGG
GGAAGAAAGTTGGCACTTTCTTTTCAGAAGTAAAGCCTGCAGGCCCGACTGTTGAGCAACAGGG
AGAAATGGCTCGATCTGGGGGAAGGATGTTGGCCACATTGGAACCTGAGCAGAGAGCAGAAATC
ATCTATCACCTGGCTGACCTGCTGACAGACCAACAGGAAGAGATCCTATTAGCCAACAAAAAAG
ACCTGGAAGAAGCAGAAGGGAGACTTGCAGGCCCTCTGCTGAAGCGCTTAAGCCTCTCCACCTC
TAAGCTGAACAGCCTGGCCATCGGGCTGCGGCAGATCGCAGCTTCCTCGCAGGACAGCGTGGGG
CGTGTCGTGCGCAGGACCCGAATTGCTAAAAACCTGGAACTTGAGCAAGTGACTGTTCCAATTG
GTGTTCTACTGGTGATCTTTGAATCTCGCCCTGACTGTTTGCCCCAGGTGGCAGCCTTGGCTAT
TGCAACTGGGAATGGCTTGTTACTCAAAGGTGGGAAGGAGGCTGCACACAGCAACCGGATTCTT
CATCTTCTAACCCAGGAGGCCCTCTCGATGCATGGAGTGAAGGAGGCAGTACAGCTGGTGAATA
CCAGAGAAGAAGTTGAAGATCTTTGCCGCCTGGACAAAATGATAGATCTGATCATTCCACGTGG
ATCTTCCCAGCTGGTCAGAGACATCCAGAAAGCAGCTAAGGGGATTCCAGTGATGGGGCACAGT
GAAGGGATCTGCCACATGTATGTGGATTCAGCAGCCAGCGTTGATAAGGTCACCAGACTTGTCA
GAGACTCTAAATGTGAATATCCAGCCGCTTGTAATGCTTTGGAGACTTTATTAATCCACCGGGA
TCTGCTGAGAACACCATTATTTGACCAGATCATTGATATGCTGAGAGTGGAACAGGTGAAAATT
CACGCTGGCCCCAAGTTTGCCTCCTATCTGACCTTCAGTCCCTCAGAGGTGAAGTCACTCCGAA
CAGAGTACGGGGACCTGGAATTGTGCATTGAAGTGGTGGACAGTGTCCAGGAAGCCATTGACCA
CATCCACAAGTATGGCAGCTCCCACACGGATGTCATTGTCACCGAGAATGAGAAAACAGCAGAG
TTCTTCCTCCAGCATGTTGATAGCGCCTGTGTGTTCTGGAATGCCAGCACACGTTTCTCTGATG
GCTACCGCTTTGGACTTGGAGCTGAGGTGGGAATCAGCACATCACGAATCCACGCCAGGGGACC
AGTAGGACTTGAAGGACTCCTTACTACTAAGTGGCTGCTTCGAGGACAAGATCATGTGGTCTCA
GACTTCTCAGAACACGGCAGTTTAAAATATCTTCATGAGAACCTCCCTGTTCCCCAGAGAAACA
CCAACTGAAAAGTGCCAGGAAACCCAGGGATGTTACAAGAGTCTTCCCAGTTGTACTAGTCCTG
AGAATCTCTGGGGAGAGGTCACATCTTTTCTTTCTACTTCCTGGAATGGCGTGCCTATTGGAAA
GTACACCTAGATGCTTTAGGGTAGTAGAATTAACTACAAATCTGGAGTGCTGAATTTGGTACTG
TCAGACTTGGCTAACATTCATTTTCCATTCCACTCTTTTAGTAAGAAAACTACTCCCTCGGATA
GGGACTTAGCTTTGCTCAGTTCAGCTCCCTTCAGTGCTAGAAACAAAGGAGTTTTCCCTCCTAA
AAGGCAAAGGAATAATCCTGGCTGCTTTTTGCGAGGTAAAGTGTCCCTTGGCATGTGGTTGATA
CCAGCAGCATCATCCCTAATAAGTCAGTGTTTCACTTCTTCCACACGTAGTCCTCTTCAAACAG
GAAGACTTGGGATTTAAAACAGGGAGCAGCTCTTCCTAGCGTTCTCACCAGAAGCGGGGACAGA
AATGGACTGAATTATTTCAAATGGGAAGATTGACCTCTTCTGTGCATCAGTGGCATTGGTAAAC
GAGCATTCCAGACATCCACAGCCCGTCCCCATCCAGGAGCGCACGTGCCTGTGATGCAGTTGGA
CCCTGAGCCGCAGACAGTGGTAAGGTCAAGATGTTCCCAGCAAGCAGGAGAAGTATCTACAGCT
ATAATGCTTGAAATTTTTATATGAATTATTTTGTCATCCTGTCCTTTTCCTCCAAAACAAAGAT
TAGAGGATTATTTTAATACTTTGAATTCTTCCCCGTTTTTAAGAAATAAAATTCTTACCAAAAG
CTTA

hide sequence

RefSeq Acc Id:

XM_005407548 ⟹ XP_005407605

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955507	1,892,087 - 1,946,419 (-)	NCBI

Sequence:

show sequence

AGACGGAAGAAAAGGGAGGCCGAGCGGGCGCCTGCATCATCCCGGCGTGGAGCGCGGCCGGGCG
GGTGGTGGCTGAGCGCGGGACGCAGGTATTGGATTAGTGACCACATCTCACCATGTTGAGTCAA
GTTTACCGCTCTGGGTTCCAGCCCTTCAACCATCGTGTTCTGCCTTGGGTCCAGTCCACAGCTG
TCTCCAGATCTTATCGTGGACAGCATTCAGCCATCAGACATGTTCGTTCTTGGAGCAACATCCC
CTTTATCACAGTACCCCTCAGTCGTGCCCATGGCAAGTCCTTTGCCCACCGAAGTGAGCTGAAG
CATGCCAAGAGGATTGTAGTGAAACTCGGCAGTGCTGTGGTGACCCGAGGAGATGAGTGTGGCC
TGGCATTGGGGCGCCTGGCATCTATTGTGGAGCAGGTATCCGTGCTACAAAATCAGGGCCGAGA
GATGATGCTGGTGACCAGTGGAGCTGTAGCCTTTGGCAAGCAGCGATTGCGCCATGAGATCCTT
CTGTCTCAAAGCGTGCGACAGGCCCTGCACTCAGGGCAGAACCAGCTGAAAGAGATGGCAATTC
CAGTCTTAGAGGCGCGAGCCTGTGCAGCTGCCGGACAGAGTGGGCTGATGGCCTTGTATGAAGC
CATGTTTACCCAGTATAGCATCTGTGCTGCCCAGATTTTGGTGACCAACCTGGATTTCCATGAT
GAGCAGAAACGCCGGAACCTCAATGGGACTCTTCATGAACTCCTTCGAATGAACATCGTCCCCA
TTGTCAACACAAATGATGCTGTTGTCCCCCCAGCTGAGCCCAACAGTGATCTGCAGGGGGTTAT
TAGTGTTAAAGATAATGATAGTCTGGCTGCCCGCCTGGCTGTGGAAATGAAAACTGACCTCCTG
ATTGTTCTTTCAGATGTAGAAGGCCTCTTTGACAGCCCCCCAGGGTCAGATGATGCAAAGCTCA
TTGATACATTTTATCCCGGTGATCAGCAGTCTGTAACATTTGGAACCAAGTCTAGAGTGGGAAT
GGGAGGCATGGAAGCCAAGGTGAAAGCAGCGCTCTGGGCTTTACAAGGTGGCACTTCCGTTGTT
ATTGCGAATGGAACCCACCCCAAGGTGTCTGGGCATGTCATCACAGACATCGTGGAGGGGAAGA
AAGTTGGCACTTTCTTTTCAGAAGTAAAGCCTGCAGGCCCGACTGTTGAGCAACAGGGAGAAAT
GGCTCGATCTGGGGGAAGGATGTTGGCCACATTGGAACCTGAGCAGAGAGCAGAAATCATCTAT
CACCTGGCTGACCTGCTGACAGACCAACAGGAAGAGATCCTATTAGCCAACAAAAAAGACCTGG
AAGAAGCAGAAGGGAGACTTGCAGGCCCTCTGCTGAAGCGCTTAAGCCTCTCCACCTCTAAGCT
GAACAGCCTGGCCATCGGGCTGCGGCAGATCGCAGCTTCCTCGCAGGACAGCGTGGGGCGTGTC
GTGCGCAGGACCCGAATTGCTAAAAACCTGGAACTTGAGCAAGTGACTGTTCCAATTGGTGTTC
TACTGGTGATCTTTGAATCTCGCCCTGACTGTTTGCCCCAGGTGGCAGCCTTGGCTATTGCAAC
TGGGAATGGCTTGTTACTCAAAGGTGGGAAGGAGGCTGCACACAGCAACCGGATTCTTCATCTT
CTAACCCAGGAGGCCCTCTCGATGCATGGAGTGAAGGAGGCAGTACAGCTGGTGAATACCAGAG
AAGAAGTTGAAGATCTTTGCCGCCTGGACAAAATGATAGATCTGATCATTCCACGTGGATCTTC
CCAGCTGGTCAGAGACATCCAGAAAGCAGCTAAGGGGATTCCAGTGATGGGGCACAGTGAAGGG
ATCTGCCACATGTATGTGGATTCAGCAGCCAGCGTTGATAAGGTCACCAGACTTGTCAGAGACT
CTAAATGTGAATATCCAGCCGCTTGTAATGCTTTGGAGACTTTATTAATCCACCGGGATCTGCT
GAGAACACCATTATTTGACCAGATCATTGATATGCTGAGAGTGGAACAGGTGAAAATTCACGCT
GGCCCCAAGTTTGCCTCCTATCTGACCTTCAGTCCCTCAGAGGTGAAGTCACTCCGAACAGAGT
ACGGGGACCTGGAATTGTGCATTGAAGTGGTGGACAGTGTCCAGGAAGCCATTGACCACATCCA
CAAGTATGGCAGCTCCCACACGGATGTCATTGTCACCGAGAATGAGAAAACAGCAGAGTTCTTC
CTCCAGCATGTTGATAGCGCCTGTGTGTTCTGGAATGCCAGCACACGTTTCTCTGATGGCTACC
GCTTTGGACTTGGAGCTGAGGTGGGAATCAGCACATCACGAATCCACGCCAGGGGACCAGTAGG
ACTTGAAGGACTCCTTACTACTAAGTGGCTGCTTCGAGGACAAGATCATGTGGTCTCAGACTTC
TCAGAACACGGCAGTTTAAAATATCTTCATGAGAACCTCCCTGTTCCCCAGAGAAACACCAACT
GAAAAGTGCCAGGAAACCCAGGGATGTTACAAGAGTCTTCCCAGTTGTACTAGTCCTGAGAATC
TCTGGGGAGAGGTCACATCTTTTCTTTCTACTTCCTGGAATGGCGTGCCTATTGGAAAGTACAC
CTAGATGCTTTAGGGTAGTAGAATTAACTACAAATCTGGAGTGCTGAATTTGGTACTGTCAGAC
TTGGCTAACATTCATTTTCCATTCCACTCTTTTAGTAAGAAAACTACTCCCTCGGATAGGGACT
TAGCTTTGCTCAGTTCAGCTCCCTTCAGTGCTAGAAACAAAGGAGTTTTCCCTCCTAAAAGGCA
AAGGAATAATCCTGGCTGCTTTTTGCGAGGTAAAGTGTCCCTTGGCATGTGGTTGATACCAGCA
GCATCATCCCTAATAAGTCAGTGTTTCACTTCTTCCACACGTAGTCCTCTTCAAACAGGAAGAC
TTGGGATTTAAAACAGGGAGCAGCTCTTCCTAGCGTTCTCACCAGAAGCGGGGACAGAAATGGA
CTGAATTATTTCAAATGGGAAGATTGACCTCTTCTGTGCATCAGTGGCATTGGTAAACGAGCAT
TCCAGACATCCACAGCCCGTCCCCATCCAGGAGCGCACGTGCCTGTGATGCAGTTGGACCCTGA
GCCGCAGACAGTGGTAAGGTCAAGATGTTCCCAGCAAGCAGGAGAAGTATCTACAGCTATAATG
CTTGAAATTTTTATATGAATTATTTTGTCATCCTGTCCTTTTCCTCCAAAACAAAGATTAGAGG
ATTATTTTAATACTTTGAATTCTTCCCCGTTTTTAAGAAATAAAATTCTTACCAAAAGCTTA

hide sequence

RefSeq Acc Id:

XM_013506238 ⟹ XP_013361692

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955507	1,892,087 - 1,946,526 (-)	NCBI

Sequence:

show sequence

GCAGCGCAGCGCACCCCGGGGCTACGGCCGCCTCACGTCAACAGCGTAGGCCCCGGCGGCCTGG
GTTTACGCCAACGCCGCCGACGTGACGTTCTCGTGGGGTATTGGATTAGTGACCACATCTCACC
ATGTTGAGTCAAGTTTACCGCTCTGGGTTCCAGCCCTTCAACCATCGTGTTCTGCCTTGGGTCC
AGTCCACAGCTGTCTCCAGATCTTATCGTGGACAGCATTCAGCCATCAGACATGTTCGTTCTTG
GAGCAACATCCCCTTTATCACAGTACCCCTCAGTCGTGCCCATGGCAAGTCCTTTGCCCACCGA
AGTGAGCTGAAGCATGCCAAGAGGATTGTAGTGAAACTCGGCAGTGCTGTGGTGACCCGAGGAG
ATGAGTGTGGCCTGGCATTGGGGCGCCTGGCATCTATTGTGGAGCAGGTATCCGTGCTACAAAA
TCAGGGCCGAGAGATGATGCTGGTGACCAGTGGAGCTGTAGCCTTTGGCAAGCAGCGATTGCGC
CATGAGATCCTTCTGTCTCAAAGCGTGCGACAGGCCCTGCACTCAGGGCAGAACCAGCTGAAAG
AGATGGCAATTCCAGTCTTAGAGGCGCGAGCCTGTGCAGCTGCCGGACAGAGTGGGCTGATGGC
CTTGTATGAAGCCATGTTTACCCAGTATAGCATCTGTGCTGCCCAGATTTTGGTGACCAACCTG
GATTTCCATGATGAGCAGAAACGCCGGAACCTCAATGGGACTCTTCATGAACTCCTTCGAATGA
ACATCGTCCCCATTGTCAACACAAATGATGCTGTTGTCCCCCCAGCTGAGCCCAACAGTGATCT
GCAGGGGGTAAATGTTATTAGTGTTAAAGATAATGATAGTCTGGCTGCCCGCCTGGCTGTGGAA
ATGAAAACTGACCTCCTGATTGTTCTTTCAGATGTAGAAGGCCTCTTTGACAGCCCCCCAGGGT
CAGATGATGCAAAGCTCATTGATACATTTTATCCCGGTGATCAGCAGTCTGTAACATTTGGAAC
CAAGTCTAGAGTGGGAATGGGAGGCATGGAAGCCAAGGTGAAAGCAGCGCTCTGGGCTTTACAA
GGTGGCACTTCCGTTGTTATTGCGAATGGAACCCACCCCAAGGTGTCTGGGCATGTCATCACAG
ACATCGTGGAGGGGAAGAAAGTTGGCACTTTCTTTTCAGAAGTAAAGCCTGCAGGCCCGACTGT
TGAGCAACAGGGAGAAATGGCTCGATCTGGGGGAAGGATGTTGGCCACATTGGAACCTGAGCAG
AGAGCAGAAATCATCTATCACCTGGCTGACCTGCTGACAGACCAACAGGAAGAGATCCTATTAG
CCAACAAAAAAGACCTGGAAGAAGCAGAAGGGAGACTTGCAGGCCCTCTGCTGAAGCGCTTAAG
CCTCTCCACCTCTAAGCTGAACAGCCTGGCCATCGGGCTGCGGCAGATCGCAGCTTCCTCGCAG
GACAGCGTGGGGCGTGTCGTGCGCAGGACCCGAATTGCTAAAAACCTGGAACTTGAGCAAGTGA
CTGTTCCAATTGGTGTTCTACTGGTGATCTTTGAATCTCGCCCTGACTGTTTGCCCCAGGTGGC
AGCCTTGGCTATTGCAACTGGGAATGGCTTGTTACTCAAAGGTGGGAAGGAGGCTGCACACAGC
AACCGGATTCTTCATCTTCTAACCCAGGAGGCCCTCTCGATGCATGGAGTGAAGGAGGCAGTAC
AGCTGGTGAATACCAGAGAAGAAGTTGAAGATCTTTGCCGCCTGGACAAAATGATAGATCTGAT
CATTCCACGTGGATCTTCCCAGCTGGTCAGAGACATCCAGAAAGCAGCTAAGGGGATTCCAGTG
ATGGGGCACAGTGAAGGGATCTGCCACATGTATGTGGATTCAGCAGCCAGCGTTGATAAGGTCA
CCAGACTTGTCAGAGACTCTAAATGTGAATATCCAGCCGCTTGTAATGCTTTGGAGACTTTATT
AATCCACCGGGATCTGCTGAGAACACCATTATTTGACCAGATCATTGATATGCTGAGAGTGGAA
CAGGTGAAAATTCACGCTGGCCCCAAGTTTGCCTCCTATCTGACCTTCAGTCCCTCAGAGGTGA
AGTCACTCCGAACAGAGTACGGGGACCTGGAATTGTGCATTGAAGTGGTGGACAGTGTCCAGGA
AGCCATTGACCACATCCACAAGTATGGCAGCTCCCACACGGATGTCATTGTCACCGAGAATGAG
AAAACAGCAGAGTTCTTCCTCCAGCATGTTGATAGCGCCTGTGTGTTCTGGAATGCCAGCACAC
GTTTCTCTGATGGCTACCGCTTTGGACTTGGAGCTGAGGTGGGAATCAGCACATCACGAATCCA
CGCCAGGGGACCAGTAGGACTTGAAGGACTCCTTACTACTAAGTGGCTGCTTCGAGGACAAGAT
CATGTGGTCTCAGACTTCTCAGAACACGGCAGTTTAAAATATCTTCATGAGAACCTCCCTGTTC
CCCAGAGAAACACCAACTGAAAAGTGCCAGGAAACCCAGGGATGTTACAAGAGTCTTCCCAGTT
GTACTAGTCCTGAGAATCTCTGGGGAGAGGTCACATCTTTTCTTTCTACTTCCTGGAATGGCGT
GCCTATTGGAAAGTACACCTAGATGCTTTAGGGTAGTAGAATTAACTACAAATCTGGAGTGCTG
AATTTGGTACTGTCAGACTTGGCTAACATTCATTTTCCATTCCACTCTTTTAGTAAGAAAACTA
CTCCCTCGGATAGGGACTTAGCTTTGCTCAGTTCAGCTCCCTTCAGTGCTAGAAACAAAGGAGT
TTTCCCTCCTAAAAGGCAAAGGAATAATCCTGGCTGCTTTTTGCGAGGTAAAGTGTCCCTTGGC
ATGTGGTTGATACCAGCAGCATCATCCCTAATAAGTCAGTGTTTCACTTCTTCCACACGTAGTC
CTCTTCAAACAGGAAGACTTGGGATTTAAAACAGGGAGCAGCTCTTCCTAGCGTTCTCACCAGA
AGCGGGGACAGAAATGGACTGAATTATTTCAAATGGGAAGATTGACCTCTTCTGTGCATCAGTG
GCATTGGTAAACGAGCATTCCAGACATCCACAGCCCGTCCCCATCCAGGAGCGCACGTGCCTGT
GATGCAGTTGGACCCTGAGCCGCAGACAGTGGTAAGGTCAAGATGTTCCCAGCAAGCAGGAGAA
GTATCTACAGCTATAATGCTTGAAATTTTTATATGAATTATTTTGTCATCCTGTCCTTTTCCTC
CAAAACAAAGATTAGAGGATTATTTTAATACTTTGAATTCTTCCCCGTTTTTAAGAAATAAAAT
TCTTACCAAAAGCTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005407604	(Get FASTA)	NCBI Sequence Viewer
	XP_005407605	(Get FASTA)	NCBI Sequence Viewer
	XP_013361692	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000002543
	ENSCLAP00000002543.1

RefSeq Acc Id:

XP_005407605 ⟸ XM_005407548

- Peptide Label:

isoform X2

- Sequence:

show sequence

MLSQVYRSGFQPFNHRVLPWVQSTAVSRSYRGQHSAIRHVRSWSNIPFITVPLSRAHGKSFAHR
SELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLR
HEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNL
DFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVISVKDNDSLAARLAVEMK
TDLLIVLSDVEGLFDSPPGSDDAKLIDTFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGG
TSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRA
EIIYHLADLLTDQQEEILLANKKDLEEAEGRLAGPLLKRLSLSTSKLNSLAIGLRQIAASSQDS
VGRVVRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIATGNGLLLKGGKEAAHSNR
ILHLLTQEALSMHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMG
HSEGICHMYVDSAASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQV
KIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKT
AEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHV
VSDFSEHGSLKYLHENLPVPQRNTN

hide sequence

RefSeq Acc Id:	XP_005407604 ⟸ XM_005407547
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UMV6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSQVYRSGFQPFNHRVLPWVQSTAVSRSYRGQHSAIRHVRSWSNIPFITVPLSRAHGKSFAHR SELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLR HEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNL DFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVE MKTDLLIVLSDVEGLFDSPPGSDDAKLIDTFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQ GGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQ RAEIIYHLADLLTDQQEEILLANKKDLEEAEGRLAGPLLKRLSLSTSKLNSLAIGLRQIAASSQ DSVGRVVRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIATGNGLLLKGGKEAAHS NRILHLLTQEALSMHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPV MGHSEGICHMYVDSAASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVE QVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDSVQEAIDHIHKYGSSHTDVIVTENE KTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQD HVVSDFSEHGSLKYLHENLPVPQRNTN hide sequence

RefSeq Acc Id:	XP_013361692 ⟸ XM_013506238
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UMV6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSQVYRSGFQPFNHRVLPWVQSTAVSRSYRGQHSAIRHVRSWSNIPFITVPLSRAHGKSFAHR SELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLR HEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNL DFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVE MKTDLLIVLSDVEGLFDSPPGSDDAKLIDTFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQ GGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQ RAEIIYHLADLLTDQQEEILLANKKDLEEAEGRLAGPLLKRLSLSTSKLNSLAIGLRQIAASSQ DSVGRVVRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIATGNGLLLKGGKEAAHS NRILHLLTQEALSMHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPV MGHSEGICHMYVDSAASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVE QVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDSVQEAIDHIHKYGSSHTDVIVTENE KTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQD HVVSDFSEHGSLKYLHENLPVPQRNTN hide sequence

RefSeq Acc Id:

ENSCLAP00000002543 ⟸ ENSCLAT00000002596

Protein Domains

Aldehyde dehydrogenase Aspartate/glutamate/uridylate kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000001841	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000002596	ENTREZGENE
	ENSCLAT00000002596.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.1160.10	UniProtKB/TrEMBL
InterPro	AceGlu_kinase-like_sf	UniProtKB/TrEMBL
	Ald_DH/histidinol_DH	UniProtKB/TrEMBL
	Ald_DH_C	UniProtKB/TrEMBL
	Ald_DH_N	UniProtKB/TrEMBL
	Aldehyde_DH_dom	UniProtKB/TrEMBL
	Asp/Glu/Uridylate_kinase	UniProtKB/TrEMBL
	G-glutamylP_reductase_CS	UniProtKB/TrEMBL
	G5K_ProBA	UniProtKB/TrEMBL
	Glu/AcGlu_kinase	UniProtKB/TrEMBL
	Glu_5kinase/COase_Synthase	UniProtKB/TrEMBL
	Glutamate_5-kinase_CS	UniProtKB/TrEMBL
	GPR_dom	UniProtKB/TrEMBL
	P5_carboxy_syn	UniProtKB/TrEMBL
NCBI Gene	Aldh18a1	ENTREZGENE
PANTHER	DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE	UniProtKB/TrEMBL
	GLUTAMATE SEMIALDEHYDE DEHYDROGENASE	UniProtKB/TrEMBL
Pfam	AA_kinase	UniProtKB/TrEMBL
	Aldedh	UniProtKB/TrEMBL
PIRSF	P5C_syn	UniProtKB/TrEMBL
PRINTS	GLU5KINASE	UniProtKB/TrEMBL
PROSITE	GLUTAMATE_5_KINASE	UniProtKB/TrEMBL
	PROA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53633	UniProtKB/TrEMBL
	SSF53720	UniProtKB/TrEMBL
UniProt	A0A8C2UMV6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Aldh18a1	aldehyde dehydrogenase 18 family member A1		aldehyde dehydrogenase 18 family, member A1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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