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Gene: Aldh18a1 (aldehyde dehydrogenase 18 family, member A1) Mus musculus
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Symbol: Aldh18a1
Name: aldehyde dehydrogenase 18 family, member A1
Description: Exhibits glutamate 5-kinase activity. Predicted to be involved in alpha-amino acid metabolic process and response to temperature stimulus. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in cataract; cutis laxa (multiple); enterocele; and hereditary spastic paraplegia (multiple). Is expressed in several structures, including alimentary system; brain; cardiovascular system; respiratory system; and sensory organ. Orthologous to human ALDH18A1 (aldehyde dehydrogenase 18 family member A1); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810433K04Rik; AI429789; aldehyde dehydrogenase family 18 member A1; delta-1-pyrroline-5-carboxylate synthase; delta-1-pyrroline-5-carboxylate synthetase; glutamate gamma-semialdehyde synthetase; MGC32233; P5CS; Pycs; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)
Orthologs:
Homo sapiens (human) : ALDH18A1 (aldehyde dehydrogenase 18 family member A1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aldh18a1 (aldehyde dehydrogenase 18 family, member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldh18a1 (aldehyde dehydrogenase 18 family member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDH18A1 (aldehyde dehydrogenase 18 family member A1)
Canis lupus familiaris (dog) : ALDH18A1 (aldehyde dehydrogenase 18 family member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101975532 (delta-1-pyrroline-5-carboxylate synthase)
Sus scrofa (pig) : ALDH18A1 (aldehyde dehydrogenase 18 family member A1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1940,550,257 - 40,588,463 (-)Ensembl
GRCm381940,550,257 - 40,588,463 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371940,624,747 - 40,662,953 (-)NCBIGRCm37mm9NCBIm37
MGSCv361940,603,568 - 40,641,680 (-)NCBImm8
Celera1941,354,703 - 41,390,340 (-)NCBICelera
Cytogenetic Map19 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Aldh18a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553733
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.