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Gene: Nprl3 (NPR3-like, GATOR1 complex subunit) Rattus norvegicus
Symbol: Nprl3
Name: NPR3-like, GATOR1 complex subunit
RGD ID: 1308665
Description: Predicted to contribute to GTPase activator activity. Predicted to be involved in several processes, including TORC1 signaling; circulatory system development; and negative regulation of TOR signaling. Predicted to localize to GATOR1 complex and lysosomal membrane. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human NPRL3 (NPR3 like, GATOR1 complex subunit); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH bisphenol A; cadmium dichloride; cocaine.
Type: protein-coding
Also known as: alpha globin regulatory element containing; alpha globin regulatory element containing gene; LOC360505; Mare; MGC124858; nitrogen permease regulator 3-like protein; nitrogen permease regulator-like 3; nitrogen permease regulator-like 3 (S. cerevisiae); RGD1308665; similar to CGTHBA protein (-14 gene protein)
Homo sapiens (human) : NPRL3 (NPR3 like, GATOR1 complex subunit)  HGNC  Alliance
Mus musculus (house mouse) : Nprl3 (nitrogen permease regulator-like 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nprl3 (NPR3 like, GATOR1 complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Canis lupus familiaris (dog) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nprl3 (NPR3 like, GATOR1 complex subunit)
Sus scrofa (pig) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Chlorocebus sabaeus (African green monkey) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Heterocephalus glaber (naked mole-rat) : Nprl3 (NPR3 like, GATOR1 complex subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01015,620,824 - 15,661,332 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,620,871 - 15,661,331 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,515,994 - 15,556,475 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,602,474 - 15,642,898 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,601,253 - 15,643,813 (+)NCBI
Celera1015,022,975 - 15,063,389 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nprl3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308665
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.