Serpinb5 (serpin family B member 5) - Rat Genome Database

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Gene: Serpinb5 (serpin family B member 5) Rattus norvegicus
Analyze
Symbol: Serpinb5
Name: serpin family B member 5
RGD ID: 69342
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to act upstream of or within several processes, including extracellular matrix organization; prostate gland morphogenesis; and regulation of epithelial cell proliferation. Predicted to be located in sarcoplasm. Predicted to be active in cornified envelope and extracellular space. Orthologous to human SERPINB5 (serpin family B member 5); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Maspin; Maspin, serine protease inhibitor; peptidase inhibitor 5; PI-5; Pi5; protease inhibitor 5; serine (or cysteine) peptidase inhibitor, clade B, member 5; serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serine (or cysteine) proteinase inhibitor, clade B, member 5; serpin B5; serpin peptidase inhibitor, clade B (ovalbumin), member 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21322,985,557 - 23,005,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,985,557 - 23,005,756 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1323,302,154 - 23,322,367 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01324,586,612 - 24,606,829 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01323,272,318 - 23,292,534 (+)NCBIRnor_WKY
Rnor_6.01326,903,052 - 26,923,250 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,903,052 - 26,923,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01332,053,528 - 32,073,726 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,037,587 - 13,057,785 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11313,037,586 - 13,057,785 (+)NCBI
Celera1322,842,781 - 22,862,980 (+)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-acetamidofluorene  (ISO)
2-deoxy-D-glucose  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
adefovir pivoxil  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
biphenyl-2-ol  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chrysene  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
curcumin  (ISO)
DDT  (ISO)
deoxycholic acid  (ISO)
diarsenic trioxide  (ISO)
dichlorine  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
doxazosin  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP)
furosemide  (EXP)
genistein  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
menadione  (ISO)
methotrexate  (ISO)
methylseleninic acid  (ISO)
microcystin RR  (ISO)
monosodium L-glutamate  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP)
ozone  (EXP)
paracetamol  (ISO)
pentane-2,3-dione  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenethyl caffeate  (EXP)
PhIP  (EXP)
procyanidin B2  (ISO)
progesterone  (ISO)
quinoline  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
succimer  (ISO)
sulindac sulfide  (ISO)
tamoxifen  (ISO)
tanespimycin  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
trichostatin A  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin. Chen WS, etal., Oncotarget. 2015 Sep 22;6(28):25962-74. doi: 10.18632/oncotarget.4504.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat. Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11. Rat and human maspins: structures, metastatic suppressor activity and mutation in prostate cancer cells. Umekita Y, etal., Cancer Lett 1997 Feb 26;113(1-2):87-93.
Additional References at PubMed
PMID:16049006   PMID:17563239   PMID:17950367   PMID:18593913   PMID:21069375   PMID:23376485   PMID:32746986   PMID:34059749  


Genomics

Comparative Map Data
Serpinb5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21322,985,557 - 23,005,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,985,557 - 23,005,756 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1323,302,154 - 23,322,367 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01324,586,612 - 24,606,829 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01323,272,318 - 23,292,534 (+)NCBIRnor_WKY
Rnor_6.01326,903,052 - 26,923,250 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,903,052 - 26,923,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01332,053,528 - 32,073,726 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,037,587 - 13,057,785 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11313,037,586 - 13,057,785 (+)NCBI
Celera1322,842,781 - 22,862,980 (+)NCBICelera
Cytogenetic Map13p11NCBI
SERPINB5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,476,958 - 63,505,085 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1863,476,958 - 63,505,085 (+)EnsemblGRCh38hg38GRCh38
GRCh371861,144,191 - 61,172,318 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,295,199 - 59,323,297 (+)NCBINCBI36Build 36hg18NCBI36
Build 341859,295,198 - 59,323,297NCBI
Celera1857,864,608 - 57,892,790 (+)NCBICelera
Cytogenetic Map18q21.33NCBI
HuRef1857,843,583 - 57,871,802 (+)NCBIHuRef
CHM1_11861,140,108 - 61,168,279 (+)NCBICHM1_1
T2T-CHM13v2.01863,682,029 - 63,710,157 (+)NCBIT2T-CHM13v2.0
Serpinb5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,788,905 - 106,811,078 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1106,788,903 - 106,811,078 (+)EnsemblGRCm39 Ensembl
GRCm381106,861,175 - 106,883,348 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,861,173 - 106,883,348 (+)EnsemblGRCm38mm10GRCm38
MGSCv371108,757,757 - 108,779,925 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361108,688,727 - 108,710,895 (+)NCBIMGSCv36mm8
Celera1109,710,530 - 109,732,695 (+)NCBICelera
Cytogenetic Map1E2.1NCBI
Serpinb5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540247,248,932 - 47,276,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540247,248,665 - 47,276,017 (+)NCBIChiLan1.0ChiLan1.0
SERPINB5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11860,148,552 - 60,176,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1860,148,552 - 60,176,624 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01856,836,403 - 56,864,533 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SERPINB5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,566,982 - 13,638,839 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,568,376 - 13,638,781 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha114,528,333 - 14,605,043 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0113,422,906 - 13,500,501 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl113,424,300 - 13,500,439 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1113,461,241 - 13,538,649 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0113,390,278 - 13,467,916 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,639,169 - 13,716,725 (-)NCBIUU_Cfam_GSD_1.0
Serpinb5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494426,828,821 - 26,851,011 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364972,069,035 - 2,089,745 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364972,067,796 - 2,089,965 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINB5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,167,646 - 158,195,796 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,167,756 - 158,195,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,646,842 - 175,666,862 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SERPINB5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11816,256,700 - 16,284,410 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1816,256,552 - 16,283,764 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660609,405,922 - 9,432,976 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serpinb5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247929,198,657 - 9,221,264 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247929,196,932 - 9,220,147 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Serpinb5
104 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:105
Count of miRNA genes:88
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000003625
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134266636Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2303031Bp326Blood pressure QTL 326arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131176653523001904Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131176653532331607Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131176653532331607Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat

Markers in Region
D13Rat60  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21323,001,779 - 23,001,904 (+)MAPPERmRatBN7.2
Rnor_6.01326,919,274 - 26,919,398NCBIRnor6.0
Rnor_5.01332,069,750 - 32,069,874UniSTSRnor5.0
RGSC_v3.41313,053,808 - 13,053,933RGDRGSC3.4
RGSC_v3.41313,053,809 - 13,053,933UniSTSRGSC3.4
RGSC_v3.11313,053,595 - 13,053,950RGD
Celera1322,859,002 - 22,859,128UniSTS
SHRSP x BN Map133.3799UniSTS
SHRSP x BN Map133.3799RGD
Cytogenetic Map13p13UniSTS
RH134638  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21323,005,295 - 23,005,505 (+)MAPPERmRatBN7.2
Rnor_6.01326,922,790 - 26,922,999NCBIRnor6.0
Rnor_5.01332,073,266 - 32,073,475UniSTSRnor5.0
RGSC_v3.41313,057,325 - 13,057,534UniSTSRGSC3.4
Celera1322,862,520 - 22,862,729UniSTS
Cytogenetic Map13p13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 7 7
Low 2 1 1 1 1 24 23 7 1
Below cutoff 2 17 16 3 16 4 4 8 11 12 2 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_057108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000003625   ⟹   ENSRNOP00000003625
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1322,985,557 - 23,005,756 (+)Ensembl
Rnor_6.0 Ensembl1326,903,052 - 26,923,250 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110683   ⟹   ENSRNOP00000079975
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1322,993,345 - 23,005,756 (+)Ensembl
RefSeq Acc Id: NM_057108   ⟹   NP_476449
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21322,985,557 - 23,005,756 (+)NCBI
Rnor_6.01326,903,052 - 26,923,250 (+)NCBI
Rnor_5.01332,053,528 - 32,073,726 (+)NCBI
RGSC_v3.41313,037,587 - 13,057,785 (+)RGD
Celera1322,842,781 - 22,862,980 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_476449 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein P70564 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_476449   ⟸   NM_057108
- UniProtKB: G3V6C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003625   ⟸   ENSRNOT00000003625
RefSeq Acc Id: ENSRNOP00000079975   ⟸   ENSRNOT00000110683
Protein Domains
SERPIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70564-F1-model_v2 AlphaFold P70564 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698752
Promoter ID:EPDNEW_R9277
Type:initiation region
Name:Serpinb5_1
Description:serpin family B member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01326,903,051 - 26,903,111EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69342 AgrOrtholog
BioCyc Gene G2FUF-18600 BioCyc
Ensembl Genes ENSRNOG00000002640 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003625 ENTREZGENE
  ENSRNOP00000003625.6 UniProtKB/TrEMBL
  ENSRNOP00000079975.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003625 ENTREZGENE
  ENSRNOT00000003625.8 UniProtKB/TrEMBL
  ENSRNOT00000110683.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Serpin_B9/Maspin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SERPINB5_serpin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116589 UniProtKB/Swiss-Prot
NCBI Gene 116589 ENTREZGENE
PANTHER PTHR11461 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Serpin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Serpinb5 PhenoGen
PRINTS MASPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217606
UniProt A0A8I5ZNQ7_RAT UniProtKB/TrEMBL
  G3V6C1 ENTREZGENE, UniProtKB/TrEMBL
  P70564 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Serpinb5  serpin family B member 5  Serpinb5  serpin peptidase inhibitor, clade B (ovalbumin), member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-01-19 Serpinb5  serpin peptidase inhibitor, clade B (ovalbumin), member 5  Serpinb5  serine (or cysteine) peptidase inhibitor, clade B, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Serpinb5  serine (or cysteine) peptidase inhibitor, clade B, member 5    serine (or cysteine) proteinase inhibitor, clade B, member 5  Name updated 1299863 APPROVED
2002-06-10 Serpinb5  serine (or cysteine) proteinase inhibitor, clade B, member 5      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference