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Gene: Lamb2 (laminin subunit beta 2) Rattus norvegicus

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Symbol:

Lamb2

Name:

laminin subunit beta 2

RGD ID:

2988

Description:

Predicted to enable integrin binding activity. Predicted to be a structural constituent of synapse-associated extracellular matrix. Predicted to be involved in several processes, including axon guidance; basement membrane assembly; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within several processes, including metanephric glomerulus development; neurogenesis; and visual perception. Predicted to be located in basement membrane and synapse. Predicted to be part of laminin-3 complex. Predicted to be active in neuromuscular junction and synaptic cleft. Used to study proteinuria. Human ortholog(s) of this gene implicated in Pierson syndrome; nephrotic syndrome type 5; and primary open angle glaucoma. Orthologous to human LAMB2 (laminin subunit beta 2); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; small cell lung carcinoma pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

laminin chain B3; Laminin chain beta 2; laminin subunit beta-2; laminin, beta 2; laminin-11 subunit beta; laminin-14 subunit beta; laminin-15 subunit beta; laminin-3 subunit beta; laminin-4 subunit beta; laminin-7 subunit beta; laminin-9 subunit beta; MGC93588; S-LAM beta; S-laminin subunit beta; SLAM

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LAMB2 (laminin subunit beta 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Lamb2 (laminin, beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lamb2 (laminin subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LAMB2 (laminin subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LAMB2 (laminin subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lamb2 (laminin subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LAMB2 (laminin subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LAMB2 (laminin subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lamb2 (laminin subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ISOC2 (isochorismatase domain containing 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Lamb2 (laminin, beta 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	LAMB2 (laminin subunit beta 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lamb2 (laminin, beta 2 (laminin S))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	lam-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	lamb2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	118,056,899 - 118,069,090 (+)	NCBI		GRCr8
mRatBN7.2	8	109,178,367 - 109,190,552 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	109,178,409 - 109,190,549 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	114,796,758 - 114,808,880 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,996,090 - 113,008,212 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,838,730 - 110,850,852 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	117,268,335 - 117,280,517 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,268,337 - 117,280,517 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	116,613,044 - 116,625,220 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	108,474,916 - 108,487,056 (+)	ENTREZGENE		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 1 (ISO)

atypical hemolytic-uremic syndrome (ISO)

autosomal recessive limb-girdle muscular dystrophy type 2P (ISO)

carnitine-acylcarnitine translocase deficiency (ISO)

cognitive disorder (ISO)

Diabetic Nephropathies (IEP)

Diffuse Mesangial Sclerosis (ISO)

focal segmental glomerulosclerosis (ISO)

focal segmental glomerulosclerosis 1 (ISO)

genetic disease (ISO)

glomerulonephritis (ISO)

kidney disease (ISO)

nephrosis (ISS)

nephrotic syndrome (ISO)

nephrotic syndrome type 5 (ISO)

Pierson syndrome (ISO,ISS)

primary open angle glaucoma (ISO)

Prostatic Neoplasms (ISO)

proteinuria (IMP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-bromohexadecanoic acid (ISO)

3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-hydroxyphenyl retinamide (ISO)

5-azacytidine (ISO)

6-propyl-2-thiouracil (EXP)

6alpha-methylprednisolone (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

apigenin (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

Brodifacoum (EXP)

bucladesine (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

cantharidin (ISO)

carbon nanotube (ISO)

chrysin (ISO)

ciglitazone (EXP)

cisplatin (EXP,ISO)

copper atom (ISO)

copper(0) (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

DDE (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

Dibutyl phosphate (ISO)

dimethyl sulfoxide (EXP)

diuron (EXP)

doxorubicin (ISO)

enalapril (EXP)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

fenamidone (ISO)

furan (EXP)

gentamycin (EXP)

glucose (ISO)

glyphosate (ISO)

griseofulvin (ISO)

hydrogen peroxide (ISO)

kaempferol (ISO)

medroxyprogesterone acetate (ISO)

menadione (ISO)

methamphetamine (ISO)

methimazole (EXP)

methylmercury chloride (ISO)

nickel atom (ISO)

oxaliplatin (EXP)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

quercetin (ISO)

rotenone (EXP)

rutin (ISO)

sodium arsenite (EXP,ISO)

sodium fluoride (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

topotecan (EXP)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ morphogenesis (IBA)

astrocyte development (IEA,ISO)

axon extension involved in regeneration (IEA,ISO)

axon guidance (IBA,IEA,ISO)

basement membrane assembly (IBA)

cell adhesion (IEA)

cell migration (IBA)

cell morphogenesis (ISO)

metanephric glomerular basement membrane development (IEA,ISO)

metanephric podocyte development (IEA,ISO)

neuromuscular junction development (IEA,ISO)

neuron projection development (ISO)

retina development in camera-type eye (IEA,ISO)

Schwann cell development (IEA,ISO)

substrate adhesion-dependent cell spreading (IBA)

synapse organization (ISO)

tissue development (IBA)

visual perception (IEA,ISO)

Cellular Component

basement membrane (IEA,ISO)

extracellular region (IEA)

laminin complex (IBA,ISO)

laminin-3 complex (IEA,ISO)

neuromuscular junction (IEA,ISO)

synapse (ISO)

synaptic cleft (IEA,ISO)

Molecular Function

integrin binding (IEA,ISO)

protein binding (ISO)

structural constituent of synapse-associated extracellular matrix (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

cell-extracellular matrix signaling pathway (IEA)

Entamoebiasis pathway (IEA)

small cell lung carcinoma pathway (IEA)

toxoplasmosis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	A missense LAMB2 mutation causes congenital nephrotic syndrome by impairing laminin secretion.	Chen YM, etal., J Am Soc Nephrol. 2011 May;22(5):849-58. doi: 10.1681/ASN.2010060632. Epub 2011 Apr 21.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction.	Hunter DD, etal., Nature 1989 Mar 16;338(6212):229-34.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Reductions in laminin beta2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose.	Schaeffer V, etal., Am J Physiol Renal Physiol. 2010 Feb;298(2):F314-22. doi: 10.1152/ajprenal.00483.2009. Epub 2009 Oct 28.
13.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14.	Identification of Missense Extracellular Matrix Gene Variants in a Large Glaucoma Pedigree and Investigation of the N700S Thrombospondin-1 Variant in Normal and Glaucomatous Trabecular Meshwork Cells.	Wirtz MK, etal., Curr Eye Res. 2022 Jan;47(1):79-90. doi: 10.1080/02713683.2021.1945109. Epub 2021 Jul 6.
15.	Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities.	Zenker M, etal., Hum Mol Genet. 2004 Nov 1;13(21):2625-32. Epub 2004 Sep 14.

Additional References at PubMed

PMID:2099832	PMID:7670489	PMID:7885444	PMID:8034675	PMID:9396756	PMID:9641682	PMID:10964500	PMID:12477932	PMID:14557481	PMID:15577901	PMID:16041630	PMID:16886065
PMID:17189701	PMID:17418794	PMID:19199708	PMID:19295126	PMID:19907020	PMID:20551380	PMID:20566382	PMID:22513850	PMID:23533145	PMID:24006456	PMID:27068509	PMID:27425256
PMID:27559042

Genomics

Comparative Map Data

Lamb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	118,056,899 - 118,069,090 (+)	NCBI		GRCr8
mRatBN7.2	8	109,178,367 - 109,190,552 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	109,178,409 - 109,190,549 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	114,796,758 - 114,808,880 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,996,090 - 113,008,212 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,838,730 - 110,850,852 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	117,268,335 - 117,280,517 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,268,337 - 117,280,517 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	116,613,044 - 116,625,220 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	108,474,916 - 108,487,056 (+)	ENTREZGENE		Celera
Cytogenetic Map	8	q32	NCBI

LAMB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	49,121,114 - 49,133,050 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	49,121,114 - 49,133,118 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	49,158,547 - 49,170,483 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	49,133,551 - 49,145,603 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	49,133,551 - 49,145,603	NCBI
Celera	3	49,115,499 - 49,127,552 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	49,217,083 - 49,229,135 (-)	NCBI		HuRef
CHM1_1	3	49,111,294 - 49,123,346 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	49,149,186 - 49,161,187 (-)	NCBI		T2T-CHM13v2.0

Lamb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	108,357,080 - 108,367,729 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	108,356,935 - 108,367,729 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	108,479,847 - 108,490,530 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	108,479,736 - 108,490,530 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	108,382,193 - 108,392,861 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	108,338,049 - 108,348,632 (+)	NCBI		MGSCv36	mm8
Celera	9	108,089,281 - 108,099,994 (+)	NCBI		Celera
Cytogenetic Map	9	F2	NCBI
cM Map	9	59.4	NCBI

Lamb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	1,115,087 - 1,127,455 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	1,115,412 - 1,127,264 (-)	NCBI	ChiLan1.0	ChiLan1.0

LAMB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	49,099,617 - 49,111,578 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	49,104,385 - 49,116,322 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	49,045,419 - 49,057,340 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	50,125,348 - 50,137,258 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	50,125,460 - 50,137,074 (-)	Ensembl	panpan1.1		panPan2

LAMB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	40,036,967 - 40,062,628 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	40,050,157 - 40,062,523 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	39,949,768 - 39,980,800 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	40,388,459 - 40,419,510 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	40,387,822 - 40,419,510 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	39,759,167 - 39,786,363 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	40,158,837 - 40,189,873 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	40,439,108 - 40,470,170 (+)	NCBI		UU_Cfam_GSD_1.0

Lamb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	64,065,681 - 64,080,848 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	826,142 - 841,337 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	826,178 - 841,304 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LAMB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	31,738,286 - 31,750,833 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	31,738,282 - 31,750,623 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	34,969,986 - 34,981,114 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LAMB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	10,523,763 - 10,535,733 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	10,523,717 - 10,536,207 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	156,545,957 - 156,558,194 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lamb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	3,145,643 - 3,159,101 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	3,145,643 - 3,158,781 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Lamb2
25 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	27
Count of miRNA genes:	23
Interacting mature miRNAs:	26
Transcripts:	ENSRNOT00000072098
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	61290298	119084929	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	73473045	118473045	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	69349194	112783834	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	71888757	116888757	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	71888757	116888757	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
631653	Bp125	Blood pressure QTL 125	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	66142385	111142385	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	100149864	120994388	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	93535351	123900184	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	95718998	123900184	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	95718998	123900184	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	76468691	121468691	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	70513503	118219066	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	89265192	114019816	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	71888757	116888757	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	71888757	116888757	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	82460758	122812818	Rat

Markers in Region

GDB:580683

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	109,179,290 - 109,180,909 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,269,256 - 117,270,874	NCBI	Rnor6.0
Rnor_5.0	8	116,613,959 - 116,615,577	UniSTS	Rnor5.0
Celera	8	108,475,798 - 108,477,416	UniSTS

GDB:580686

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	8	118,059,141 - 118,060,128 (+)	Marker Load Pipeline
mRatBN7.2	8	109,180,603 - 109,181,590 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,270,569 - 117,271,555	NCBI	Rnor6.0
Rnor_5.0	8	116,615,272 - 116,616,258	UniSTS	Rnor5.0
Celera	8	108,477,111 - 108,478,097	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X16563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000072098 ⟹ ENSRNOP00000065052

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	109,178,409 - 109,190,549 (+)	Ensembl
Rnor_6.0 Ensembl	8	117,268,337 - 117,280,517 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083578 ⟹ ENSRNOP00000072697

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	109,178,410 - 109,190,549 (+)	Ensembl
Rnor_6.0 Ensembl	8	117,268,375 - 117,280,510 (+)	Ensembl

RefSeq Acc Id:

NM_012974 ⟹ NP_037106

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	118,056,947 - 118,069,087 (+)	NCBI
mRatBN7.2	8	109,178,409 - 109,190,549 (+)	NCBI
Rnor_6.0	8	117,268,374 - 117,280,514 (+)	NCBI
Rnor_5.0	8	116,613,044 - 116,625,220 (+)	NCBI
Celera	8	108,474,916 - 108,487,056 (+)	ENTREZGENE

Sequence:

show sequence

AGTGACTGCTGGTCGGACCCTGGGACAGACTGAGGGCCTGGAGGGAAACCAGCCCAGTACCCAC
ACGGATGGAGTGGGCCTCAGGAAAACCAGGGAGGGGCAGGCAGGGACAGCCTGTGCCATGGGAA
CTTCGCTTGGGCCTACTTCTAAGTGTGCTGGCTGCCACATTGGCCCAAGTCCCATCCTTGGATG
TACCTGGCTGTTCTCGAGGAAGCTGCTATCCAGCCACCGGTGACCTGTTGGTGGGCCGTGCAGA
CAGACTGACAGCCTCCTCCACGTGTGGCTTGCATAGCCCTCAACCCTACTGTATTGTCAGTCAC
CTGCAGGATGAAAAGAAGTGCTTCCTGTGTGACTCCCGACGTCCCTTCTCTGCTCGAGACAACC
CAAATAGTCACCGGATCCAGAATGTAGTCACTAGCTTTGCGCCACAACGCCGGACGGCCTGGTG
GCAGTCGGAGAACGGTGTTCCGATGGTCACCATCCAACTGGACCTGGAAGCTGAGTTTCATTTC
ACCCACCTCATCATGACCTTCAAGACATTTCGTCCTGCGGCCATGCTGGTGGAGCGCTCTGCAG
ACTTCGGCCGCACGTGGCGTGTCTACCGATATTTTTCCTACGACTGCGGGGCTGACTTCCCAGG
AATCCCGCTGGCCCCGCCGCGTCGCTGGGATGATGTAGTGTGTGAGTCCCGCTACTCAGAAATT
GAGCCATCTACTGAAGGCGAGGTCATCTATCGTGTGCTGGATCCTGCTATTCCTATTCCAGACC
CCTACAGCTCACGGATTCAGAACCTGTTGAAGATCACCAACCTCCGTGTGAACCTCACCCGGCT
TCACACACTGGGAGACAACTTGCTTGACCCACGGCGGGAGATCCGGGAAAAATATTATTATGCT
CTCTATGAACTTGTCATCCGCGGGAACTGCTTCTGCTATGGACATGCCTCACAGTGTGCGCCTG
CACCAGGGGCACCGGCCCATGCTGAGGGCATGGTACATGGGGCCTGTATTTGCAAGCACAATAC
TCGTGGGCTCAACTGTGAGCAGTGTCAGGATTTCTATCAGGACCTTCCCTGGCATCCTGCTGAG
GATGGCCATACTCACGCCTGTCGGAAGTGTGAGTGCAACGGGCATAGTCATAGCTGCCACTTTG
ACATGGCTGTGTACCTGGCATCTGGAAACGTAAGTGGAGGTGTCTGCGATGGCTGTCAGCACAA
CACGGCTGGGCGCCACTGCGAGCTCTGCCGGCCCTTCTTCTACCGTGACCCAACCAAGGACATG
CGGGATCCAGCTGCGTGCCGTCCTTGTGACTGTGACCCAATGGGTTCTCAAGACGGTGGCCGCT
GTGATTCCCATGATGACCCTGTGCTAGGTCTGGTCTCAGGCCAGTGTCGCTGCAAAGAACACGT
GGTTGGCACTCGCTGCCAGCAATGCCGGGACGGCTTCTTTGGACTTAGTGCCAGCAACCCTCGA
GGATGTCAGCGTTGTCAGTGTAACTCAAGGGGCACAGTGCCTGGGGGCACCCCTTGTGACTCCA
GTAGTGGAACCTGTTTCTGCAAGCGTCTGGTGACTGGAGACGGCTGTGACCGCTGTCTGCCTGG
CCACTGGGGCCTGAGCCATGACCTGCTAGGCTGCCGCCCCTGTGACTGTGATGTGGGCGGTGCC
TTGGATCCTCAGTGTGATGAAGCCACGGGTCAGTGCCCGTGCCGCCCACACATGATTGGGCGGC
GCTGTGAACAAGTACAGCCTGGCTACTTCCGGCCTTTTCTAGACCATCTAACCTGGGAGGCTGA
GGGTGCCCATGGGCAGGTGCTTGAGGTGGTAGAACGTCTGGTGACCAACCGAGAGACTCCGTCC
TGGACTGGTGTAGGCTTTGTGCGACTGCGGGAAGGTCAGGAAGTGGAGTTCCTGGTGACCTCTT
TGCCTAGGGCCATGGACTATGACCTGCTACTGCGCTGGGAGCCCCAGGTTCCTGAGCAGTGGGC
AGAGCTGGAATTGGTGGTGCAGCGCCCAGGGCCTGTGTCTGCACACAGTCCGTGTGGGCACGTG
CTGCCGAGGGATGACCGCATTCAGGGGATGCTTCACCCAAACACCAGGGTTTTGGTGTTTCCCA
GACCTGTCTGCCTTGAGCCTGGTCTCTCCTACAAGCTGAAGTTGAAATTGACTGGAACAGGGGG
ACGTGCCCATCCTGAAACCCCATACTCTGGATCTGGAATACTCATTGACTCGCTGGTGCTGCAG
CCCCATGTCTTGATGCTAGAGATGTTTAGTGGGGGGGATGCTGCTGCCCTGGAACGCCGTACCA
CCTTTGAACGCTACCGCTGCCATGAGGAAGGTCTGATGCCCAGCAAGACCCCCCTATCTGAGGC
CTGCGTTCCCCTCCTCATCAGTGCGTCCTCCCTGGTCTACAATGGCGCCTTGCCCTGCCAGTGT
GACCCTCAAGGCTCACTGAGTTCCGAATGCAATCCTCATGGTGGCCAGTGCCGGTGCAAGCCTG
GAGTGGTTGGACGACGCTGTGATGCCTGTGCTACTGGCTACTATGGCTTTGGGCCCGCAGGCTG
TCAAGCCTGCCAGTGTAGTCCCGACGGAGCACTCAGTGCCCTGTGTGAAGGGACTAGTGGACAG
TGTCTCTGCCGAACCGGTGCCTTTGGTCTTCGCTGTGACCACTGTCAACGTGGCCAGTGGGGTT
TCCCTAACTGCCGGCCGTGTGTCTGCAACGGGCGTGCAGATGAGTGTGACGCCCACACAGGCGC
TTGCCTGGGCTGCCGTGATTACACAGGGGGCGAGCACTGTGAGAGGTGCATTGCTGGTTTTCAT
GGGGACCCACGGCTGCCATATGGGGGCCAGTGCCGGCCTTGTCCCTGCCCTGAAGGCCCCGGGA
GCCAGCGACACTTTGCTACTTCATGTCACCGGGATGGATATTCCCAGCAAATTGTGTGCCACTG
TCGAGCAGGCTACACAGGGCTTCGGTGTGAGGCTTGTGCCCCCGGGCACTTTGGGGACCCATCC
AAGCCAGGTGGCAGGTGCCAACTGTGTGAGTGCAGTGGGAACATTGACCCCACGGATCCCGGTG
CCTGTGATCCCCACACGGGGCAATGCTTGCGCTGTTTACACCACACGGAGGGGCCCCACTGTGG
CCATTGCAAGCCTGGCTTCCATGGGCAAGCTGCCCGACAGAGCTGTCACCGCTGTACCTGCAAC
CTTCTGGGCACAGATCCCCAGCGGTGCCCATCTACAGACCTGTGCCATTGTGACCCAAGCACTG
GGCAGTGCCCATGCCTCCCCCATGTCCAAGGCCTCAGTTGCGACCGTTGTGCCCCCAACTTTTG
GAACTTTACCAGTGGACGTGGCTGCCAGCCTTGTGCTTGTCACCCAAGCCGGGCCAGAGGCCCT
ACCTGCAATGAGTTCACAGGGCAGTGCCACTGTCATGCTGGCTTTGGTGGGAGGACCTGTTCTG
AGTGCCAAGAGCTCCACTGGGGAGACCCTGGACTGCAGTGCCGCGCCTGTGACTGTGATCCCAG
AGGAATAGACAAACCCCAATGTCATCGTTCTACTGGTCACTGTAGCTGCCGCCCAGGCGTGTCT
GGCGTGCGCTGCGACCAGTGTGCTCGTGGCTTCTCGGGTGTTTTTCCTGCTTGTCACCCCTGCC
ATGCATGCTTTGGAGACTGGGATCGTGTGGTACAGGACCTTGCTGCTCGTACGCGGCGCCTGGA
GCAGTGGGCTCAGGAATTGCAGCAAACGGGTGTGCTGGGTGCCTTTGAGAGCAGCTTTTTAAAC
CTGCAGGGGAAGCTGGGAATGGTGCAGGCCATCGTGGCTGCCCGCAACACCTCAGCTGCGTCTA
CTGCAAAGCTTGTAGAGGCCACAGAGGGACTGCGTCATGAAATTGGGAAGACCACTGAACGCCT
GACTCAGTTAGAAGCAGAGCTCACAGATGTACAGGATGAGAACTTCAATGCCAACCATGCACTC
AGTGGTCTGGAGAGAGACGGGCTCGCACTTAATCTCACACTGAGGCAGCTTGACCAGCATCTGG
ATATCCTCAAACACTCAAATTTCTTAGGTGCCTATGACAGCATCCGACATGCCCACAGTCAGTC
TACAGAAGCAGAGCGCCGGGCCAATGCCTCCACCTTTGCAATACCCAGCCCTGTGAGCAACTCA
GCAGATACCCGGCGTCGGGCAGAAGTGCTAATGGGTGCCCAAAGAGAGAACTTCAACCGCCAGC
ACTTGGCCAACCAGCAGGCACTTGGACGGCTGTCCACACACACCCATACCCTGAGCCTGACGGG
AGTAAATGAGCTGGTGTGTGGGGCCCCAGGGGACGCACCCTGTGCTACCAGCCCTTGTGGGGGT
GCTGGATGTCGGGATGAGGATGGGCAACCCCGCTGTGGTGGCCTCGGTTGCAGTGGAGCAGCAG
CCACAGCAGATCTAGCACTGGGCCGGGCTCGGCACACACAGGCAGAGCTGCAGAGAGCGCTGGT
AGAAGGTGGTGGCATCCTCAGCCGAGTGTCTGAGACTCGTCGGCAGGCAGAGGAGGCCCAGCAA
CGAGCACAGGCAGCCCTGGACAAGGCTAATGCTTCTAGGGGCCAAGTGGAGCAGGCCAATCAGG
AGCTTCGAGAACTTATCCAGAATGTGAAGGACTTCCTCAGCCAGGAGGGAGCTGATCCCGACAG
TATTGAAATGGTAGCAACACGGGTGCTAGACATCTCCATCCCAGCCTCGCCTGAGCAGATCCAG
CGCCTAGCAAGTGAGATTGCAGAACGTGTCCGAAGCCTGGCGGATGTGGACACAATCCTGGCAC
ATACCATGGGGGATGTGCGTCGGGCTGAACAGCTACTGCAAGATGCACAGCGGGCACGGAGCCG
GGCTGAGGGTGAGAGACAGAAGGCAGAGACAGTCCAAGCGGCACTGGAGGAGGCCCAGAGGGCA
CAGGGAGCTGCTCAGGGCGCCATCCGGGGAGCAGTGGTTGACACAAAAAACACAGAGCAGACCC
TGCAGCAGGTCCAGGAGAGGATGGCAGGTACAGAGCAGTCTCTGAACTCTGCTAGTGAGCGGGC
TCGGCAGTTACATGCCCTTCTGGAAGCCCTGAAACTGAAAAGGGCAGGAAACAGCCTGGCAGCA
TCTACAGCTGAAGAGACAGCAGGCAGTGCCCAGAGCCGTGCCAGGGAGGCTGAGAAACAGCTAC
GGGAACAAGTAGGTGACCAGTACCAAACTGTGAGGGCGTTGGCTGAACGGAAGGCTGAAGGTGT
TCTGGCCGCACAAGCCAGAGCAGAACAACTGCGGGATGAGGCTCGGGGTCTGTTGCAGGCTGCT
CAGGACAAGTTGCAGCGGCTACAGGAACTGGAGGGCACATATGAAGAGAATGAACGCGAACTGG
AGGTCAAAGCGGCTCAGCTGGATGGGCTGGAGGCCAGGATGCGCAGTGTGCTTCAGGCAATCAA
CCTGCAGGTCCAGATCTACAACACCTGCCAGTGACCACTCCCTAGGGTTTAGCCTTGTCTCCAA
GCACAGTTCCACATGCGTTTGTCCGCACATTAAAGAGCTCTTGGCTAGCAAGTGCTTTCAATAA
ACCAGTGTGAACC

hide sequence

RefSeq Acc Id:

XM_006243709 ⟹ XP_006243771

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	118,056,899 - 118,069,090 (+)	NCBI
mRatBN7.2	8	109,178,367 - 109,190,552 (+)	NCBI
Rnor_6.0	8	117,268,335 - 117,280,517 (+)	NCBI
Rnor_5.0	8	116,613,044 - 116,625,220 (+)	NCBI

Sequence:

show sequence

CTTTACTCAAAGTCGTCAGAGTCTCTCAGATTGTGGAGGAGTGACTGCTGGTCGGACCCTGGGA
CAGACTGAGGGCCTGGAGGGAAACCAGCCCAGTACCCACACGGTCAGGGATGGAGTGGGCCTCA
GGAAAACCAGGGAGGGGCAGGCAGGGACAGCCTGTGCCATGGGAACTTCGCTTGGGCCTACTTC
TAAGTGTGCTGGCTGCCACATTGGCCCAAGTCCCATCCTTGGATGTACCTGGCTGTTCTCGAGG
AAGCTGCTATCCAGCCACCGGTGACCTGTTGGTGGGCCGTGCAGACAGACTGACAGCCTCCTCC
ACGTGTGGCTTGCATAGCCCTCAACCCTACTGTATTGTCAGTCACCTGCAGGATGAAAAGAAGT
GCTTCCTGTGTGACTCCCGACGTCCCTTCTCTGCTCGAGACAACCCAAATAGTCACCGGATCCA
GAATGTAGTCACTAGCTTTGCGCCACAACGCCGGACGGCCTGGTGGCAGTCGGAGAACGGTGTT
CCGATGGTCACCATCCAACTGGACCTGGAAGCTGAGTTTCATTTCACCCACCTCATCATGACCT
TCAAGACATTTCGTCCTGCGGCCATGCTGGTGGAGCGCTCTGCAGACTTCGGCCGCACGTGGCG
TGTCTACCGATATTTTTCCTACGACTGCGGGGCTGACTTCCCAGGAATCCCGCTGGCTCCGCCG
CGTCGCTGGGATGATGTAGTGTGTGAGTCCCGCTACTCAGAAATTGAGCCATCTACTGAAGGCG
AGGTCATCTATCGTGTGCTGGATCCTGCTATTCCTATTCCAGACCCCTACAGCTCACGGATTCA
GAACCTGTTGAAGATCACCAACCTCCGTGTGAACCTCACCCGGCTTCACACACTGGGAGACAAC
TTGCTTGACCCACGGCGGGAGATCCGGGAAAAATATTATTATGCTCTCTATGAACTTGTCATCC
GCGGGAACTGCTTCTGCTATGGACATGCCTCACAGTGTGCGCCTGCACCAGGGGCACCGGCCCA
TGCTGAGGGCATGGTACATGGGGCCTGTATTTGCAAGCACAATACTCGTGGGCTCAACTGTGAG
CAGTGTCAGGATTTCTATCAGGACCTTCCCTGGCATCCTGCTGAGGATGGCCATACTCACGCCT
GTCGGAAGTGTGAGTGCAACGGGCATAGTCATAGCTGCCACTTTGACATGGCTGTGTACCTGGC
ATCTGGAAACGTAAGTGGAGGTGTCTGCGATGGCTGTCAGCACAACACGGCTGGGCGCCACTGC
GAGCTCTGCCGGCCCTTCTTCTACCGTGACCCAACCAAGGACATGCGGGATCCAGCTGCGTGCC
GTCCTTGTGACTGTGACCCAATGGGTTCTCAAGACGGTGGCCGCTGTGATTCCCATGATGACCC
TGTGCTAGGTCTGGTCTCAGGCCAGTGTCGCTGCAAAGAACACGTGGTTGGCACTCGCTGCCAG
CAATGCCGGGACGGCTTCTTTGGACTTAGTGCCAGCAACCCTCGAGGATGTCAGCGTTGTCAGT
GTAACTCAAGGGGCACAGTGCCTGGGGGCACCCCTTGTGACTCCAGTAGTGGAACCTGTTTCTG
CAAGCGTCTGGTGACTGGAGACGGCTGTGACCGCTGTCTGCCTGGCCACTGGGGCCTGAGCCAT
GACCTGCTAGGCTGCCGCCCCTGTGACTGTGATGTGGGCGGTGCCTTGGATCCTCAGTGTGATG
AAGCCACGGGTCAGTGCCGCTGCCGCCCACACATGATTGGGCGGCGCTGTGAACAAGTACAGCC
TGGCTACTTCCGGCCTTTTCTAGACCATCTAACCTGGGAGGCTGAGGGTGCCCATGGGCAGGTG
CTTGAGGTGGTAGAACGTCTGGTGACCAACCGAGAGACTCCGTCCTGGACTGGTGTAGGCTTTG
TGCGACTGCGGGAAGGTCAGGAAGTGGAGTTCCTGGTGACCTCTTTGCCTAGGGCCATGGACTA
TGACCTGCTACTGCGCTGGGAGCCCCAGGTTCCTGAGCAGTGGGCAGAGCTGGAATTGGTGGTG
CAGCGCCCAGGGCCTGTGTCTGCACACAGTCCGTGTGGGCACGTGCTGCCGAGGGATGACCGCA
TTCAGGGGATGCTTCACCCAAACACCAGGGTTTTGGTGTTTCCCAGACCTGTCTGCCTTGAGCC
TGGTCTCTCCTACAAGCTGAAGTTGAAATTGACTGGAACAGGGGGACGTGCCCATCCTGAAACC
CCATACTCTGGATCTGGAATACTCATTGACTCGCTGGTGCTGCAGCCCCATGTCTTGATGCTAG
AGATGTTTAGTGGGGGGGATGCTGCTGCCCTGGAACGCCGTACCACCTTTGAACGCTACCGCTG
CCATGAGGAAGGTCTGATGCCCAGCAAGACCCCCCTATCTGAGGCCTGCGTTCCCCTCCTCATC
AGTGCGTCCTCCCTGGTCTACAATGGCGCCTTGCCCTGCCAGTGTGACCCTCAAGGCTCACTGA
GTTCCGAATGCAATCCTCATGGTGGCCAGTGCCGGTGCAAGCCTGGAGTGGTTGGACGACGCTG
TGATGCCTGTGCTACTGGCTACTATGGCTTTGGGCCCGCAGGCTGTCAAGCCTGCCAGTGTAGT
CCTGACGGAGCACTCAGTGCCCTGTGTGAAGGGACTAGTGGACAGTGTCTCTGCCGAACCGGTG
CCTTTGGTCTTCGCTGTGACCACTGTCAACGTGGCCAGTGGGGTTTCCCTAACTGCCGGCCGTG
TGTCTGCAACGGGCGTGCAGATGAGTGTGACGCCCACACAGGCGCTTGCCTGGGCTGCCGTGAT
TACACAGGGGGCGAGCACTGTGAGAGGTGCATTGCTGGTTTTCATGGGGACCCACGGCTGCCAT
ATGGGGGCCAGTGCCGGCCTTGTCCCTGCCCTGAAGGCCCCGGGAGCCAGCGACACTTTGCTAC
TTCATGTCACCGGGATGGATATTCCCAGCAAATTGTGTGCCACTGTCGAGCAGGCTACACAGGG
CTTCGGTGTGAGGCTTGTGCCCCCGGGCACTTTGGGGACCCATCCAAGCCAGGTGGCAGGTGCC
AACTGTGTGAGTGCAGTGGGAACATTGACCCCACGGATCCCGGTGCCTGTGATCCCCACACGGG
GCAATGCTTGCGCTGTTTACACCACACGGAGGGGCCCCACTGTGGCCATTGCAAGCCTGGCTTC
CATGGGCAAGCTGCCCGACAGAGCTGTCACCGCTGTACCTGCAACCTTCTGGGCACAGATCCCC
AGCGGTGCCCATCTACAGACCTGTGCCATTGTGACCCAAGCACTGGGCAGTGCCCATGCCTCCC
CCATGTCCAAGGCCTCAGTTGCGACCGTTGTGCCCCCAACTTTTGGAACTTTACCAGTGGACGT
GGCTGCCAGCCTTGTGCTTGTCACCCAAGCCGGGCCAGAGGCCCTACCTGCAATGAGTTCACAG
GGCAGTGCCACTGTCATGCTGGCTTTGGTGGGAGGACCTGTTCTGAGTGCCAAGAGCTCCACTG
GGGAGACCCTGGACTGCAGTGCCGCGCCTGTGACTGTGATCCCAGAGGAATAGACAAACCCCAA
TGTCATCGTTCTACTGGTCACTGTAGCTGCCGCCCAGGCGTGTCTGGCGTGCGCTGCGACCAGT
GTGCTCGTGGCTTCTCGGGTGTTTTTCCTGCTTGTCACCCCTGCCATGCATGCTTTGGAGACTG
GGATCGTGTGGTACAGGACCTTGCTGCTCGTACGCGGCGCCTGGAGCAGTGGGCTCAGGAATTG
CAGCAAACGGGTGTGCTGGGTGCCTTTGAGAGCAGCTTTTTAAACCTGCAGGGGAAGCTGGGAA
TGGTGCAGGCCATCGTGGCTGCCCGCAACACCTCAGCTGCGTCTACTGCAAAGCTTGTAGAGGC
CACAGAGGGACTGCGTCATGAAATTGGGAAGACCACTGAGCGCCTGACTCAGTTAGAAGCAGAG
CTCACAGATGTACAGGATGAGAACTTCAATGCCAACCATGCACTCAGTGGTCTGGAGAGAGACG
GGCTCGCACTTAATCTCACACTGAGGCAGCTTGACCAGCATCTGGATATCCTCAAACACTCAAA
TTTCTTAGGTGCCTATGACAGCATCCGACATGCCCACAGTCAGTCTACAGAAGCAGAGCGCCGG
GCCAATGCCTCCACCTTTGCAATACCCAGCCCTGTGAGCAACTCAGCAGATACCCGGCGTCGGG
CAGAAGTGCTAATGGGTGCCCAAAGAGAGAACTTCAACCGCCAGCACTTGGCCAACCAGCAGGC
ACTTGGACGGCTGTCCACACACACCCATACCCTGAGCCTGACGGGAGTAAATGAGCTGGTGTGT
GGGGCCCCAGGGGACGCACCCTGTGCTACCAGCCCTTGTGGGGGTGCTGGATGTCGGGATGAGG
ATGGGCAACCCCGCTGTGGTGGCCTCGGTTGCAGTGGAGCAGCAGCCACAGCAGATCTAGCACT
GGGCCGGGCTCGGCACACACAGGCAGAGCTGCAGAGAGCGCTGGTAGAAGGTGGTGGCATCCTC
AGCCGAGTGTCTGAGACTCGTCGGCAGGCAGAGGAGGCCCAGCAACGAGCACAGGCAGCCCTGG
ACAAGGCTAATGCTTCTAGGGGCCAAGTGGAGCAGGCCAATCAGGAGCTTCGAGAACTTATCCA
GAATGTGAAGGACTTCCTCAGCCAGGAGGGAGCTGATCCCGACAGTATTGAAATGGTAGCAACA
CGGGTGCTAGACATCTCCATCCCAGCCTCGCCTGAGCAGATCCAGCGCCTAGCAAGTGAGATTG
CAGAACGTGTCCGAAGCCTGGCGGATGTGGACACAATCCTGGCACATACCATGGGGGATGTGCG
TCGGGCTGAACAGCTACTGCAAGATGCACAGCGGGCACGGAGCCGGGCTGAGGGTGAGAGACAG
AAGGCAGAGACAGTCCAAGCGGCACTGGAGGAGGCCCAGAGGGCACAGGGAGCTGCTCAGGGCG
CCATCCGGGGAGCAGTGGTTGACACAAAAAACACAGAGCAGACCCTGCAGCAGGTCCAGGAGAG
GATGGCAGGTACAGAGCAGTCTCTGAACTCTGCTAGTGAGCGGGCTCGGCAGTTACATGCCCTT
CTGGAAGCCCTGAAACTGAAAAGGGCAGGAAACAGCCTGGCAGCATCTACAGCTGAAGAGACAG
CAGGCAGTGCCCAGAGCCGTGCCAGGGAGGCTGAGAAACAGCTACGGGAACAAGTAGGTGACCA
GTACCAAACTGTGAGGGCGTTGGCTGAACGGAAGGCTGAAGGTGTTCTGGCCGCACAAGCCAGA
GCAGAACAACTGCGGGATGAGGCTCGGGGTCTGTTGCAGGCTGCTCAGGACAAGTTGCAGCGGC
TACAGGAACTGGAGGGCACATATGAAGAGAATGAACGCGAACTGGAGGTCAAAGCGGCTCAGCT
GGATGGGCTGGAGGCCAGGATGCGCAGTGTGCTTCAGGCAATCAACCTGCAGGTCCAGATCTAC
AACACCTGCCAGTGACCACTCCCTAGGGTTTAGCCTTGTCTCCAAGCACAGTTCCACATGCGTT
TGTCCGCACATTAAAGAGCTCTTGGCTAGCAAGTGCTTTCAATAAACCAGTGTGAACCACC

hide sequence

RefSeq Acc Id:

XM_039080881 ⟹ XP_038936809

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	118,056,905 - 118,069,090 (+)	NCBI
mRatBN7.2	8	109,178,367 - 109,190,552 (+)	NCBI

RefSeq Acc Id:

XM_039080882 ⟹ XP_038936810

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	118,057,132 - 118,069,090 (+)	NCBI
mRatBN7.2	8	109,178,582 - 109,190,552 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_037106	(Get FASTA)	NCBI Sequence Viewer
	XP_006243771	(Get FASTA)	NCBI Sequence Viewer
	XP_038936809	(Get FASTA)	NCBI Sequence Viewer
	XP_038936810	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88400	(Get FASTA)	NCBI Sequence Viewer
	CAA34561	(Get FASTA)	NCBI Sequence Viewer
	EDL77168	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000065052.1
	ENSRNOP00000072697.1
GenBank Protein	P15800	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_037106 ⟸ NM_012974
- Peptide Label:	precursor
- UniProtKB:	P15800 (UniProtKB/Swiss-Prot), Q5M7W9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEWASGKPGRGRQGQPVPWELRLGLLLSVLAATLAQVPSLDVPGCSRGSCYPATGDLLVGRADR LTASSTCGLHSPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPNSHRIQNVVTSFAPQRRTAWWQ SENGVPMVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWRVYRYFSYDCGADFPGI PLAPPRRWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLH TLGDNLLDPRREIREKYYYALYELVIRGNCFCYGHASQCAPAPGAPAHAEGMVHGACICKHNTR GLNCEQCQDFYQDLPWHPAEDGHTHACRKCECNGHSHSCHFDMAVYLASGNVSGGVCDGCQHNT AGRHCELCRPFFYRDPTKDMRDPAACRPCDCDPMGSQDGGRCDSHDDPVLGLVSGQCRCKEHVV GTRCQQCRDGFFGLSASNPRGCQRCQCNSRGTVPGGTPCDSSSGTCFCKRLVTGDGCDRCLPGH WGLSHDLLGCRPCDCDVGGALDPQCDEATGQCPCRPHMIGRRCEQVQPGYFRPFLDHLTWEAEG AHGQVLEVVERLVTNRETPSWTGVGFVRLREGQEVEFLVTSLPRAMDYDLLLRWEPQVPEQWAE LELVVQRPGPVSAHSPCGHVLPRDDRIQGMLHPNTRVLVFPRPVCLEPGLSYKLKLKLTGTGGR AHPETPYSGSGILIDSLVLQPHVLMLEMFSGGDAAALERRTTFERYRCHEEGLMPSKTPLSEAC VPLLISASSLVYNGALPCQCDPQGSLSSECNPHGGQCRCKPGVVGRRCDACATGYYGFGPAGCQ ACQCSPDGALSALCEGTSGQCLCRTGAFGLRCDHCQRGQWGFPNCRPCVCNGRADECDAHTGAC LGCRDYTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHRDGYSQQIVCHCR AGYTGLRCEACAPGHFGDPSKPGGRCQLCECSGNIDPTDPGACDPHTGQCLRCLHHTEGPHCGH CKPGFHGQAARQSCHRCTCNLLGTDPQRCPSTDLCHCDPSTGQCPCLPHVQGLSCDRCAPNFWN FTSGRGCQPCACHPSRARGPTCNEFTGQCHCHAGFGGRTCSECQELHWGDPGLQCRACDCDPRG IDKPQCHRSTGHCSCRPGVSGVRCDQCARGFSGVFPACHPCHACFGDWDRVVQDLAARTRRLEQ WAQELQQTGVLGAFESSFLNLQGKLGMVQAIVAARNTSAASTAKLVEATEGLRHEIGKTTERLT QLEAELTDVQDENFNANHALSGLERDGLALNLTLRQLDQHLDILKHSNFLGAYDSIRHAHSQST EAERRANASTFAIPSPVSNSADTRRRAEVLMGAQRENFNRQHLANQQALGRLSTHTHTLSLTGV NELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLGCSGAAATADLALGRARHTQAELQRALVE GGGILSRVSETRRQAEEAQQRAQAALDKANASRGQVEQANQELRELIQNVKDFLSQEGADPDSI EMVATRVLDISIPASPEQIQRLASEIAERVRSLADVDTILAHTMGDVRRAEQLLQDAQRARSRA EGERQKAETVQAALEEAQRAQGAAQGAIRGAVVDTKNTEQTLQQVQERMAGTEQSLNSASERAR QLHALLEALKLKRAGNSLAASTAEETAGSAQSRAREAEKQLREQVGDQYQTVRALAERKAEGVL AAQARAEQLRDEARGLLQAAQDKLQRLQELEGTYEENERELEVKAAQLDGLEARMRSVLQAINL QVQIYNTCQ hide sequence

RefSeq Acc Id:	XP_006243771 ⟸ XM_006243709
- Peptide Label:	isoform X1
- UniProtKB:	M0R6K0 (UniProtKB/TrEMBL), A6I359 (UniProtKB/TrEMBL), Q5M7W9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEWASGKPGRGRQGQPVPWELRLGLLLSVLAATLAQVPSLDVPGCSRGSCYPATGDLLVGRADR LTASSTCGLHSPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPNSHRIQNVVTSFAPQRRTAWWQ SENGVPMVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWRVYRYFSYDCGADFPGI PLAPPRRWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLH TLGDNLLDPRREIREKYYYALYELVIRGNCFCYGHASQCAPAPGAPAHAEGMVHGACICKHNTR GLNCEQCQDFYQDLPWHPAEDGHTHACRKCECNGHSHSCHFDMAVYLASGNVSGGVCDGCQHNT AGRHCELCRPFFYRDPTKDMRDPAACRPCDCDPMGSQDGGRCDSHDDPVLGLVSGQCRCKEHVV GTRCQQCRDGFFGLSASNPRGCQRCQCNSRGTVPGGTPCDSSSGTCFCKRLVTGDGCDRCLPGH WGLSHDLLGCRPCDCDVGGALDPQCDEATGQCRCRPHMIGRRCEQVQPGYFRPFLDHLTWEAEG AHGQVLEVVERLVTNRETPSWTGVGFVRLREGQEVEFLVTSLPRAMDYDLLLRWEPQVPEQWAE LELVVQRPGPVSAHSPCGHVLPRDDRIQGMLHPNTRVLVFPRPVCLEPGLSYKLKLKLTGTGGR AHPETPYSGSGILIDSLVLQPHVLMLEMFSGGDAAALERRTTFERYRCHEEGLMPSKTPLSEAC VPLLISASSLVYNGALPCQCDPQGSLSSECNPHGGQCRCKPGVVGRRCDACATGYYGFGPAGCQ ACQCSPDGALSALCEGTSGQCLCRTGAFGLRCDHCQRGQWGFPNCRPCVCNGRADECDAHTGAC LGCRDYTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHRDGYSQQIVCHCR AGYTGLRCEACAPGHFGDPSKPGGRCQLCECSGNIDPTDPGACDPHTGQCLRCLHHTEGPHCGH CKPGFHGQAARQSCHRCTCNLLGTDPQRCPSTDLCHCDPSTGQCPCLPHVQGLSCDRCAPNFWN FTSGRGCQPCACHPSRARGPTCNEFTGQCHCHAGFGGRTCSECQELHWGDPGLQCRACDCDPRG IDKPQCHRSTGHCSCRPGVSGVRCDQCARGFSGVFPACHPCHACFGDWDRVVQDLAARTRRLEQ WAQELQQTGVLGAFESSFLNLQGKLGMVQAIVAARNTSAASTAKLVEATEGLRHEIGKTTERLT QLEAELTDVQDENFNANHALSGLERDGLALNLTLRQLDQHLDILKHSNFLGAYDSIRHAHSQST EAERRANASTFAIPSPVSNSADTRRRAEVLMGAQRENFNRQHLANQQALGRLSTHTHTLSLTGV NELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLGCSGAAATADLALGRARHTQAELQRALVE GGGILSRVSETRRQAEEAQQRAQAALDKANASRGQVEQANQELRELIQNVKDFLSQEGADPDSI EMVATRVLDISIPASPEQIQRLASEIAERVRSLADVDTILAHTMGDVRRAEQLLQDAQRARSRA EGERQKAETVQAALEEAQRAQGAAQGAIRGAVVDTKNTEQTLQQVQERMAGTEQSLNSASERAR QLHALLEALKLKRAGNSLAASTAEETAGSAQSRAREAEKQLREQVGDQYQTVRALAERKAEGVL AAQARAEQLRDEARGLLQAAQDKLQRLQELEGTYEENERELEVKAAQLDGLEARMRSVLQAINL QVQIYNTCQ hide sequence

Ensembl Acc Id:

ENSRNOP00000072697 ⟸ ENSRNOT00000083578

Ensembl Acc Id:

ENSRNOP00000065052 ⟸ ENSRNOT00000072098

RefSeq Acc Id:	XP_038936809 ⟸ XM_039080881
- Peptide Label:	isoform X2
- UniProtKB:	Q5M7W9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038936810 ⟸ XM_039080882
- Peptide Label:	isoform X3
- UniProtKB:	Q5M7W9 (UniProtKB/TrEMBL)

Protein Domains

Laminin EGF-like Laminin IV type B Laminin N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P15800-F1-model_v2	AlphaFold	P15800	1-1801	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696303

Promoter ID:

EPDNEW_R6827

Type:

multiple initiation site

Name:

Lamb2_1

Description:

laminin subunit beta 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	117,268,362 - 117,268,422	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2988	AgrOrtholog
BioCyc Gene	G2FUF-29139	BioCyc
Ensembl Genes	ENSRNOG00000047768	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000072098.3	UniProtKB/TrEMBL
	ENSRNOT00000083578.2	UniProtKB/TrEMBL
Gene3D-CATH	Galactose-binding domain-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tie2 ligand-binding domain superfamily	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7107264	IMAGE-MGC_LOAD
InterPro	EGF-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin/Netrin_ECM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin_EGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin_IV_B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25473	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93588	IMAGE-MGC_LOAD
NCBI Gene	25473	ENTREZGENE
PANTHER	LAMININ SUBUNIT GAMMA-1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NETRIN/LAMININ-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Laminin_EGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LAMININ_IV_B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Lamb2	PhenoGen
PRINTS	EGFLAMININ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	EGF_1	UniProtKB/Swiss-Prot
	EGF_2	UniProtKB/Swiss-Prot
	EGF_LAM_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF_LAM_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LAMININ_IVB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LAMININ_NTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000047768	RatGTEx
SMART	EGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF_Lam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LamNT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	EGF/Laminin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC217452
UniProt	A6I359	ENTREZGENE, UniProtKB/TrEMBL
	LAMB2_RAT	UniProtKB/Swiss-Prot
	M0R6K0	ENTREZGENE, UniProtKB/TrEMBL
	P15800	ENTREZGENE
	Q5M7W9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-26	Lamb2	laminin subunit beta 2	Lamb2	laminin, beta 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Lamb2	Laminin chain beta 2			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	found in the synaptic cleft of the neuromuscular junction	728961

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)