LAMB2 (laminin subunit beta 2) - Rat Genome Database
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Gene: LAMB2 (laminin subunit beta 2) Canis lupus familiaris
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Symbol: LAMB2
Name: laminin subunit beta 2
RGD ID: 12331778
Description: INVOLVED IN cell morphogenesis involved in differentiation (ortholog); neuron projection development (ortholog); synapse organization (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2P (ortholog); cognitive disorder (ortholog); Diabetic Nephropathies (ortholog); FOUND IN basement membrane (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: laminin subunit beta-2; laminin, gamma 1 (formerly LAMB2); LOW QUALITY PROTEIN: laminin subunit beta-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2040,050,157 - 40,062,523 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12040,036,967 - 40,062,628 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
LAMB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2040,050,157 - 40,062,523 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12040,036,967 - 40,062,628 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LAMB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,121,114 - 49,133,118 (-)EnsemblGRCh38hg38GRCh38
GRCh38349,121,114 - 49,133,066 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,158,547 - 49,170,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,133,551 - 49,145,603 (-)NCBINCBI36hg18NCBI36
Build 34349,133,551 - 49,145,603NCBI
Celera349,115,499 - 49,127,552 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,217,083 - 49,229,135 (-)NCBIHuRef
CHM1_1349,111,294 - 49,123,346 (-)NCBICHM1_1
Lamb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,357,046 - 108,367,729 (+)NCBIGRCm39mm39
GRCm389108,479,847 - 108,490,530 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,479,736 - 108,490,530 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,382,193 - 108,392,861 (+)NCBIGRCm37mm9NCBIm37
MGSCv369108,338,049 - 108,348,632 (+)NCBImm8
Celera9108,089,281 - 108,099,994 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.4NCBI
Lamb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08117,268,335 - 117,280,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,268,337 - 117,280,517 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,613,044 - 116,625,220 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,474,916 - 108,487,056 (+)ENTREZGENECelera
Cytogenetic Map8q32NCBI
Lamb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,115,087 - 1,127,455 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,115,412 - 1,127,264 (-)NCBIChiLan1.0ChiLan1.0
LAMB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,125,348 - 50,137,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,125,460 - 50,137,074 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,045,419 - 49,057,340 (-)NCBIMhudiblu_PPA_v0panPan3
Lamb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936529826,178 - 841,304 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,738,284 - 31,771,220 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,738,282 - 31,750,623 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,969,986 - 34,981,114 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMB2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,523,763 - 10,535,733 (-)NCBI
ChlSab1.1 Ensembl2210,523,717 - 10,536,207 (-)Ensembl
Lamb2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,145,643 - 3,158,781 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 17 1 6 1 6 6 6 10 6
Low 5 5 5 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005632554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005632555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014121972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022406743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038427782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038503457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038566470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038630615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000018765   ⟹   ENSCAFP00000017386
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2040,050,157 - 40,062,523 (+)Ensembl
RefSeq Acc Id: XM_005632554   ⟹   XP_005632611
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12040,047,731 - 40,062,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005632555   ⟹   XP_005632612
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12040,050,773 - 40,062,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014121972   ⟹   XP_013977447
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12040,038,732 - 40,062,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022406742   ⟹   XP_022262450
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12040,039,936 - 40,062,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022406743   ⟹   XP_022262451
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12040,036,967 - 40,062,628 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005632611 (Get FASTA)   NCBI Sequence Viewer  
  XP_005632612 (Get FASTA)   NCBI Sequence Viewer  
  XP_013977447 (Get FASTA)   NCBI Sequence Viewer  
  XP_022262451 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283703 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283704 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283705 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283706 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283707 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283708 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283709 (Get FASTA)   NCBI Sequence Viewer  
  XP_038283710 (Get FASTA)   NCBI Sequence Viewer  
  XP_038311917 (Get FASTA)   NCBI Sequence Viewer  
  XP_038311918 (Get FASTA)   NCBI Sequence Viewer  
  XP_038311919 (Get FASTA)   NCBI Sequence Viewer  
  XP_038311921 (Get FASTA)   NCBI Sequence Viewer  
  XP_038359385 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422391 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422392 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422393 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422394 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422395 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422396 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422397 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422398 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486536 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486537 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486538 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486539 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486540 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486541 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486542 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486543 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013977447   ⟸   XM_014121972
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005632611   ⟸   XM_005632554
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005632612   ⟸   XM_005632555
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_022262451   ⟸   XM_022406743
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_022262450   ⟸   XM_022406742
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000017386   ⟸   ENSCAFT00000018765


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011744 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000017386 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018765 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.1490 UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_IV_B UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
  Laminin_N_sf UniProtKB/TrEMBL
NCBI Gene LAMB2 ENTREZGENE
Pfam Laminin_EGF UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
PROSITE EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAMININ_IVB UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
UniProt E2R4J1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:42568 ENTREZGENE