Paxip1 (PAX interacting protein 1) - Rat Genome Database

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Gene: Paxip1 (PAX interacting protein 1) Rattus norvegicus
Analyze
Symbol: Paxip1
Name: PAX interacting protein 1
RGD ID: 1307547
Description: Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; regulation of primary metabolic process; and vasculogenesis. Predicted to act upstream of or within DNA damage response. Predicted to be part of MLL3/4 complex. Predicted to be active in nucleus. Orthologous to human PAXIP1 (PAX interacting protein 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; flutamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC311944; PAX interacting (with transcription-activation domain) protein 1; PAX-interacting protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr848,258,930 - 8,310,490 (+)NCBIGRCr8
mRatBN7.247,525,132 - 7,576,659 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl47,525,004 - 7,576,548 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx412,535,163 - 12,586,700 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.048,349,408 - 8,400,945 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.046,695,594 - 6,747,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.043,956,931 - 4,008,326 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl43,959,640 - 4,008,326 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.043,996,608 - 4,047,988 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,790,532 - 2,839,246 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.142,717,068 - 2,839,242 (+)NCBI
Celera42,704,414 - 2,753,568 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Paxip1Ratautistic disorder  ISORGD:13168048554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106|PMID:30208311
Paxip1Ratholoprosencephaly 3  ISORGD:13168048554872ClinVar Annotator: match by term: Holoprosencephaly 3ClinVarPMID:10631160|PMID:10749657|PMID:16254195|PMID:19603532|PMID:20425842|PMID:21976454|PMID:23370340|PMID:24095820|PMID:28492532|PMID:29992659|PMID:31334757

1 to 20 of 57 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Paxip1Rat1,2-dimethylhydrazine decreases expressionISORGD:131680564804641,2-Dimethylhydrazine results in decreased expression of PAXIP1 mRNACTDPMID:22206623
Paxip1Rat17alpha-ethynylestradiol multiple interactionsISORGD:13168056480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PAXIP1 mRNACTDPMID:17942748
Paxip1Rat17beta-estradiol affects expressionISORGD:13168046480464Estradiol affects the expression of PAXIP1 mRNACTDPMID:22574217
Paxip1Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642,2',4,4'-tetrabromodiphenyl ether results in increased expression of PAXIP1 mRNACTDPMID:27291303
Paxip1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:13168056480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PAXIP1 mRNA; Tetrachlorodibenzodioxin promotes the more ...CTDPMID:17942748|PMID:19654925
Paxip1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13168056480464Tetrachlorodibenzodioxin affects the expression of PAXIP1 mRNACTDPMID:26377647
Paxip1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13168056480464Tetrachlorodibenzodioxin results in increased expression of PAXIP1 mRNACTDPMID:17942748|PMID:19465110
Paxip1Rat2-butoxyethanol increases expressionISORGD:13168056480464n-butoxyethanol results in increased expression of PAXIP1 mRNACTDPMID:19812364
Paxip1Rat4,4'-sulfonyldiphenol decreases expressionISORGD:13168056480464bisphenol S results in decreased expression of PAXIP1 mRNACTDPMID:39298647
Paxip1Rat4-hydroxyphenyl retinamide increases expressionISORGD:13168056480464Fenretinide results in increased expression of PAXIP1 mRNACTDPMID:28973697
Paxip1Rataflatoxin B1 increases methylationISORGD:13168046480464Aflatoxin B1 results in increased methylation of PAXIP1 geneCTDPMID:27153756
Paxip1Rataristolochic acid A decreases expressionISORGD:13168046480464aristolochic acid I results in decreased expression of PAXIP1 mRNACTDPMID:33212167
Paxip1Ratarsane multiple interactionsISORGD:13168046480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...CTDPMID:39836092
Paxip1Ratarsenic atom multiple interactionsISORGD:13168046480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...CTDPMID:39836092
Paxip1Ratbenzo[a]pyrene diol epoxide I decreases expressionISORGD:131680464804647,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PAXIP1 mRNACTDPMID:20382639
Paxip1Ratbisphenol A increases expressionISORGD:13168056480464bisphenol A results in increased expression of PAXIP1 mRNACTDPMID:26063408
Paxip1Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of PAXIP1 mRNACTDPMID:25181051
Paxip1Ratcadmium dichloride decreases expressionISORGD:13168046480464Cadmium Chloride results in decreased expression of PAXIP1 mRNACTDPMID:38568856
Paxip1Ratcadmium sulfate multiple interactionsISORGD:13168056480464cadmium sulfate affects the reaction [MTF1 affects the expression of PAXIP1 mRNA]CTDPMID:16221973
Paxip1RatCGP 52608 multiple interactionsISORGD:13168046480464CGP 52608 promotes the reaction [RORA protein binds to PAXIP1 gene]CTDPMID:28238834

1 to 20 of 57 rows

Biological Process
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Paxip1Ratadipose tissue development involved_inISORGD:13168051624291 PMID:19583951RGDPMID:19583951
Paxip1Ratbiological_process  ND 159840710/2014: no relevant rat dataRGD 
Paxip1Ratchorion development involved_inISORGD:13168051624291 PMID:18710940RGDPMID:18710940
Paxip1Ratchromatin remodeling involved_inISORGD:13168041624291 PMID:17178841RGDPMID:17178841
Paxip1RatDNA damage response involved_inISORGD:13168051624291 PMID:19124460RGDPMID:19124460
Paxip1RatDNA damage response involved_inIEAUniProtKB-KW:KW-02271600115GO_REF:0000043UniProtGO_REF:0000043
Paxip1RatDNA damage response acts_upstream_of_or_withinISORGD:13168051624291 PMID:17500065RGDPMID:17500065
Paxip1RatDNA damage response, signal transduction by p53 class mediator involved_inISORGD:13168041624291 PMID:15456759, PMID:17690115RGDPMID:15456759|PMID:17690115
Paxip1Ratendothelial cell migration involved_inISORGD:13168051624291 PMID:18710940RGDPMID:18710940
Paxip1Ratnegative regulation of DNA-binding transcription factor activity involved_inISORGD:13168041624291 PMID:11940591RGDPMID:11940591
Paxip1Ratpositive regulation of isotype switching involved_inISORGD:13168051624291 PMID:20671152RGDPMID:20671152
Paxip1Ratpositive regulation of isotype switching to IgG isotypes involved_inISORGD:13168051624291 PMID:26744420RGDPMID:26744420
Paxip1Ratpositive regulation of protein ubiquitination involved_inISORGD:13168051624291 PMID:18353733RGDPMID:18353733
Paxip1Ratpositive regulation of transcription initiation by RNA polymerase II involved_inISORGD:13168051624291 PMID:19583951, PMID:20671152RGDPMID:19583951|PMID:20671152
Paxip1Ratpositive regulation of transcription initiation by RNA polymerase II involved_inIBAMGI:1890430|PANTHER:PTN001506019|UniProtKB:Q6ZW491600115GO_REF:0000033GO_CentralGO_REF:0000033
Paxip1Ratpositive regulation of transcription initiation by RNA polymerase II involved_inISORGD:13168041624291 PMID:17925232RGDPMID:17925232
Paxip1Ratregulation of cell cycle G2/M phase transition involved_inISORGD:13168051624291 PMID:19124460RGDPMID:19124460
Paxip1Ratresponse to ionizing radiation involved_inISORGD:13168041624291 PMID:15456759RGDPMID:15456759
Paxip1Ratvasculogenesis involved_inISORGD:13168051624291 PMID:18710940RGDPMID:18710940
1 to 19 of 19 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Paxip1Rathistone methyltransferase complex part_ofISORGD:13168041624291 PMID:17925232RGDPMID:17925232
Paxip1Rathistone methyltransferase complex part_ofISORGD:13168051624291 PMID:17500065RGDPMID:17500065
Paxip1RatMLL3/4 complex part_ofISORGD:13168041624291 PMID:17500065, PMID:23508102RGDPMID:17500065|PMID:23508102
Paxip1Ratnucleus located_inISORGD:13168041624291 PMID:15456759, PMID:17690115RGDPMID:15456759|PMID:17690115
Paxip1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Paxip1Ratnucleus is_active_inIBAPANTHER:PTN001143114|PANTHER:PTN0027548121600115GO_REF:0000033GO_CentralGO_REF:0000033
Paxip1Ratnucleus located_inISORGD:13168051624291 PMID:10908331, PMID:17500065, PMID:20671152RGDPMID:10908331|PMID:17500065|PMID:20671152

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Paxip1Ratprotein binding enablesISORGD:13168051624291UniProtKB:P32114|UniProtKB:P32114-2|UniProtKB:Q02650|UniProtKB:Q12888|UniProtKB:Q99L02|UniProtKB:Q9BTK6 PMID:10908331, PMID:17500065, PMID:17925232, PMID:19124460, PMID:21552207, PMID:26744420RGDPMID:10908331|PMID:17500065|PMID:17925232|PMID:19124460|PMID:21552207|PMID:26744420
Paxip1Ratprotein binding enablesISORGD:1316804,UniProtKB:Q6ZW49-11624291UniProtKB:P16104 PMID:22064073RGDPMID:22064073
Paxip1Ratprotein binding enablesISORGD:1316804,UniProtKB:Q6ZW49-21624291UniProtKB:Q15555|UniProtKB:Q96HA1|UniProtKB:Q9UKK6 PMID:25416956RGDPMID:25416956
Paxip1Ratprotein binding enablesISORGD:13168041624291UniProtKB:O60356|UniProtKB:P05067|UniProtKB:P48730-2|UniProtKB:P61964|UniProtKB:Q12888|UniProtKB:Q15291|UniProtKB:Q9BTK6|UniProtKB:Q9UBL3 PMID:11940591, PMID:15456759, PMID:17178841, PMID:17500065, PMID:17925232, PMID:19124460, PMID:24981860, PMID:27705803, PMID:28514442, PMID:32814053, PMID:33961781RGDPMID:11940591|PMID:15456759|PMID:17178841|PMID:17500065|PMID:17925232|PMID:19124460|PMID:24981860|PMID:27705803|PMID:28514442|PMID:32814053|PMID:33961781

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Paxip1Rathistone modification pathway   ISORGD:13168049479053 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Shilatifard A Annu Rev Biochem. 2012;81:65-95. doi: 10.1146/annurev-biochem-051710-134100.
PMID:10908331   PMID:11940591   PMID:15456759   PMID:17178841   PMID:17500065   PMID:17690115   PMID:17925232   PMID:18353733   PMID:18710940   PMID:19124460   PMID:19583951   PMID:20671152  
PMID:26744420  



Paxip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr848,258,930 - 8,310,490 (+)NCBIGRCr8
mRatBN7.247,525,132 - 7,576,659 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl47,525,004 - 7,576,548 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx412,535,163 - 12,586,700 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.048,349,408 - 8,400,945 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.046,695,594 - 6,747,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.043,956,931 - 4,008,326 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl43,959,640 - 4,008,326 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.043,996,608 - 4,047,988 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,790,532 - 2,839,246 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.142,717,068 - 2,839,242 (+)NCBI
Celera42,704,414 - 2,753,568 (-)NCBICelera
Cytogenetic Map4q11NCBI
PAXIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387154,943,690 - 155,003,411 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7154,943,687 - 155,003,124 (-)EnsemblGRCh38hg38GRCh38
GRCh377154,735,400 - 154,794,834 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367154,366,333 - 154,425,615 (-)NCBINCBI36Build 36hg18NCBI36
Build 347154,173,048 - 154,232,306NCBI
Celera7149,152,557 - 149,211,836 (-)NCBICelera
Cytogenetic Map7q36.2NCBI
HuRef7148,468,426 - 148,527,705 (-)NCBIHuRef
CHM1_17154,743,784 - 154,803,135 (-)NCBICHM1_1
T2T-CHM13v2.07156,118,967 - 156,178,685 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27153,963,422 - 154,022,702 (-)NCBI
Paxip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39527,947,044 - 27,999,326 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl527,945,078 - 27,996,689 (-)EnsemblGRCm39 Ensembl
GRCm38527,740,080 - 27,791,672 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl527,740,080 - 27,791,691 (-)EnsemblGRCm38mm10GRCm38
MGSCv37528,067,205 - 28,117,879 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36528,071,452 - 28,122,126 (-)NCBIMGSCv36mm8
Celera525,287,864 - 25,339,859 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map513.23NCBI
Paxip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554918,177,422 - 8,219,766 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554918,177,422 - 8,219,764 (-)NCBIChiLan1.0ChiLan1.0
PAXIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26191,372,868 - 191,432,198 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1743,383,480 - 43,442,465 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07146,546,658 - 146,605,912 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17158,274,193 - 158,329,139 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7158,276,798 - 158,330,911 (-)Ensemblpanpan1.1panPan2
PAXIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,066,289 - 18,116,007 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,066,246 - 18,112,506 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1618,699,205 - 18,749,159 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01619,794,777 - 19,844,723 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1619,794,777 - 19,844,705 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11618,166,085 - 18,216,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01618,746,356 - 18,796,284 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01618,799,076 - 18,849,057 (-)NCBIUU_Cfam_GSD_1.0
Paxip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051183,415,214 - 3,463,432 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365279,440,036 - 9,484,245 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365279,440,129 - 9,488,215 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAXIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl183,066,848 - 3,111,240 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1183,066,853 - 3,111,239 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2183,227,951 - 3,250,496 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAXIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121123,095,968 - 123,156,157 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21123,095,966 - 123,155,800 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607219,215,604 - 19,275,681 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Paxip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248002,653,732 - 2,707,161 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248002,653,381 - 2,709,261 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Paxip1
127 total Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
4 2827327 2827328 T G snv SS/JrHsdMcwi (MDC), FHH/EurMcwi (MDC) View more Information

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:39
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000009439
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat

1 to 10 of 20 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000009439   ⟹   ENSRNOP00000009439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl47,525,004 - 7,575,997 (+)Ensembl
Rnor_6.0 Ensembl43,959,640 - 4,008,326 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099077   ⟹   ENSRNOP00000081191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl47,530,970 - 7,575,997 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104160   ⟹   ENSRNOP00000097277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl47,525,128 - 7,576,548 (+)Ensembl
RefSeq Acc Id: NM_001107844   ⟹   NP_001101314
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr848,258,966 - 8,310,490 (+)NCBI
mRatBN7.247,525,132 - 7,576,659 (+)NCBI
Rnor_6.043,959,640 - 4,008,326 (+)NCBI
Rnor_5.043,996,608 - 4,047,988 (+)NCBI
RGSC_v3.442,790,532 - 2,839,246 (+)RGD
Celera42,704,414 - 2,753,568 (-)RGD
Sequence:
RefSeq Acc Id: XM_063285937   ⟹   XP_063142007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr848,258,930 - 8,310,490 (+)NCBI
RefSeq Acc Id: XM_063285938   ⟹   XP_063142008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr848,258,930 - 8,310,490 (+)NCBI
RefSeq Acc Id: XM_063285939   ⟹   XP_063142009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr848,259,253 - 8,310,490 (+)NCBI
1 to 11 of 11 rows
Protein RefSeqs NP_001101314 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142007 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142008 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142009 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86409 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009439.6
  ENSRNOP00000081191.1
  ENSRNOP00000097277
  ENSRNOP00000097277.1
  ENSRNOP00000107761
  ENSRNOP00000111583
1 to 11 of 11 rows
RefSeq Acc Id: NP_001101314   ⟸   NM_001107844
- UniProtKB: A0A8I5ZSF2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009439   ⟸   ENSRNOT00000009439
Ensembl Acc Id: ENSRNOP00000081191   ⟸   ENSRNOT00000099077
Ensembl Acc Id: ENSRNOP00000097277   ⟸   ENSRNOT00000104160
RefSeq Acc Id: XP_063142007   ⟸   XM_063285937
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZSF2 (UniProtKB/TrEMBL)
BRCT

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSX6-F1-model_v2 AlphaFold D3ZSX6 1-824 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-46125 BioCyc
Ensembl Genes ENSRNOG00000007131 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009439.6 UniProtKB/TrEMBL
  ENSRNOT00000099077.1 UniProtKB/TrEMBL
  ENSRNOT00000104160 ENTREZGENE
  ENSRNOT00000104160.1 UniProtKB/TrEMBL
  ENSRNOT00000126337 ENTREZGENE
  ENSRNOT00000168947 ENTREZGENE
Gene3D-CATH 3.40.50.10190 UniProtKB/TrEMBL
InterPro BRCT UniProtKB/TrEMBL
  BRCT_dom_sf UniProtKB/TrEMBL
  DDR_Transcriptional_Reg UniProtKB/TrEMBL
KEGG Report rno:311944 UniProtKB/TrEMBL
NCBI Gene 311944 ENTREZGENE
PANTHER PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN UniProtKB/TrEMBL
  PAX-INTERACTING PROTEIN 1 UniProtKB/TrEMBL
Pfam BRCT UniProtKB/TrEMBL
  BRCT_2 UniProtKB/TrEMBL
  PTCB-BRCT UniProtKB/TrEMBL
  RTT107_BRCT_5 UniProtKB/TrEMBL
PhenoGen Paxip1 PhenoGen
PROSITE BRCT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007131 RatGTEx
SMART BRCT UniProtKB/TrEMBL
Superfamily-SCOP BRCT UniProtKB/TrEMBL
UniProt A0A8I5ZSF2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GMG2_RAT UniProtKB/TrEMBL
  A6KJK7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSX6 ENTREZGENE, UniProtKB/TrEMBL
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Paxip1  PAX interacting protein 1  Paxip1  PAX interacting (with transcription-activation domain) protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Paxip1  PAX interacting (with transcription-activation domain) protein 1   Paxip1_predicted  PAX interacting (with transcription-activation domain) protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2008-01-09 Paxip1_predicted  PAX interacting (with transcription-activation domain) protein 1 (predicted)  LOC681792  similar to Pax transcription activation domain interacting protein  Data merged from RGD:1591614 1643240 APPROVED
2006-11-20 LOC681792  similar to Pax transcription activation domain interacting protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Paxip1_predicted  PAX interacting (with transcription-activation domain) protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED