Polk (DNA polymerase kappa) - Rat Genome Database

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Gene: Polk (DNA polymerase kappa) Rattus norvegicus
Analyze
Symbol: Polk
Name: DNA polymerase kappa
RGD ID: 620058
Description: Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in cellular response to UV; error-prone translesion synthesis; and nucleotide-excision repair, DNA gap filling. Predicted to act upstream of or within DNA repair. Predicted to be located in nuclear body. Predicted to be active in nucleus. Predicted to colocalize with site of DNA damage. Orthologous to human POLK (DNA polymerase kappa); PARTICIPATES IN nucleotide excision repair pathway; INTERACTS WITH ammonium chloride; bisphenol A; trichloroethene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Dinb1; DNA-directed DNA polymerase kappa; polymerase (DNA directed) kappa; polymerase (DNA) kappa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2227,822,228 - 27,882,331 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl227,822,679 - 27,882,313 (-)Ensembl
Rnor_6.0227,305,718 - 27,364,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,305,728 - 27,364,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0246,417,808 - 46,477,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4226,952,022 - 27,012,088 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1226,875,113 - 26,875,624 (-)NCBI
Celera223,868,651 - 23,928,707 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. DNA polymerases and repair synthesis in NER in human cells. Lehmann AR DNA Repair (Amst). 2011 Jul 15;10(7):730-3. doi: 10.1016/j.dnarep.2011.04.023. Epub 2011 May 20.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions. Okochi E, etal., Jpn J Cancer Res 2002 May;93(5):501-6.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:12555660   PMID:20227374   PMID:28297716  


Genomics

Comparative Map Data
Polk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2227,822,228 - 27,882,331 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl227,822,679 - 27,882,313 (-)Ensembl
Rnor_6.0227,305,718 - 27,364,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,305,728 - 27,364,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0246,417,808 - 46,477,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4226,952,022 - 27,012,088 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1226,875,113 - 26,875,624 (-)NCBI
Celera223,868,651 - 23,928,707 (-)NCBICelera
Cytogenetic Map2q12NCBI
POLK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38575,511,891 - 75,609,991 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl575,511,756 - 75,601,144 (+)EnsemblGRCh38hg38GRCh38
GRCh37574,807,716 - 74,905,816 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,843,337 - 74,930,889 (+)NCBINCBI36hg18NCBI36
Build 34574,843,336 - 74,930,889NCBI
Celera570,701,054 - 70,789,056 (+)NCBI
Cytogenetic Map5q13.3NCBI
HuRef570,012,832 - 70,100,786 (+)NCBIHuRef
CHM1_1574,240,383 - 74,328,367 (+)NCBICHM1_1
T2T-CHM13v2.0575,992,960 - 76,091,061 (+)NCBI
Polk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391396,617,195 - 96,679,087 (-)NCBIGRCm39mm39
GRCm39 Ensembl1396,617,198 - 96,679,087 (-)Ensembl
GRCm381396,480,687 - 96,542,579 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1396,480,690 - 96,542,579 (-)EnsemblGRCm38mm10GRCm38
MGSCv371397,250,644 - 97,312,440 (-)NCBIGRCm37mm9NCBIm37
MGSCv361397,581,388 - 97,643,184 (-)NCBImm8
Celera13100,116,241 - 100,179,060 (-)NCBICelera
Cytogenetic Map13D1NCBI
Polk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,161,222 - 25,228,524 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,164,749 - 25,228,064 (-)NCBIChiLan1.0ChiLan1.0
POLK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1540,313,114 - 40,365,841 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl540,311,526 - 40,401,003 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0539,700,659 - 39,788,727 (-)NCBIMhudiblu_PPA_v0panPan3
POLK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1330,793,893 - 30,860,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl330,712,571 - 30,859,106 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha332,036,886 - 32,103,334 (-)NCBI
ROS_Cfam_1.0330,716,706 - 30,790,391 (-)NCBI
ROS_Cfam_1.0 Ensembl330,717,013 - 30,789,573 (-)Ensembl
UMICH_Zoey_3.1330,654,748 - 30,720,406 (-)NCBI
UNSW_CanFamBas_1.0330,624,393 - 30,691,008 (-)NCBI
UU_Cfam_GSD_1.0331,002,435 - 31,068,944 (-)NCBI
Polk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213189,596,918 - 189,658,957 (+)NCBI
SpeTri2.0NW_0049365491,199,810 - 1,261,889 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl284,538,050 - 84,656,234 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1284,555,648 - 84,619,490 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2286,174,657 - 86,250,880 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POLK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,842,887 - 69,948,285 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl469,872,752 - 69,948,249 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604918,628,236 - 18,719,870 (+)NCBIVero_WHO_p1.0
Polk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249052,800,693 - 2,844,516 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249052,801,160 - 2,844,549 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D2Uwm16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2227,824,117 - 27,824,231 (+)MAPPERmRatBN7.2
Rnor_6.0227,307,167 - 27,307,280NCBIRnor6.0
Rnor_5.0246,419,691 - 46,419,804UniSTSRnor5.0
RGSC_v3.4226,953,470 - 26,953,584RGDRGSC3.4
RGSC_v3.4226,953,471 - 26,953,584UniSTSRGSC3.4
RGSC_v3.1226,873,839 - 26,873,953RGD
Celera223,870,100 - 23,870,221UniSTS
Cytogenetic Map2q12UniSTS
BE101594  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2227,839,495 - 27,839,646 (+)MAPPERmRatBN7.2
Rnor_6.0227,321,949 - 27,322,099NCBIRnor6.0
Rnor_5.0246,434,790 - 46,434,940UniSTSRnor5.0
RGSC_v3.4226,969,352 - 26,969,502UniSTSRGSC3.4
Celera223,886,180 - 23,886,330UniSTS
RH 3.4 Map213.3UniSTS
Cytogenetic Map2q12UniSTS
BG372536  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2227,825,169 - 27,825,320 (+)MAPPERmRatBN7.2
Rnor_6.0227,308,219 - 27,308,369NCBIRnor6.0
Rnor_5.0246,420,743 - 46,420,893UniSTSRnor5.0
RGSC_v3.4226,954,523 - 26,954,673UniSTSRGSC3.4
Celera223,871,160 - 23,871,310UniSTS
RH 3.4 Map21041.4UniSTS
Cytogenetic Map2q12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22699957143154682Rat
1643006Pain1Pain QTL 13.630.005mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)22699957148268661Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:453
Count of miRNA genes:239
Interacting mature miRNAs:286
Transcripts:ENSRNOT00000033952
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 7 5
Low 3 43 57 41 18 41 8 11 74 35 34 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000078639   ⟹   ENSRNOP00000073092
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl227,822,679 - 27,882,313 (-)Ensembl
Rnor_6.0 Ensembl227,305,728 - 27,364,906 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091418   ⟹   ENSRNOP00000070520
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl227,822,679 - 27,882,313 (-)Ensembl
Rnor_6.0 Ensembl227,306,759 - 27,343,998 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094510   ⟹   ENSRNOP00000092732
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl227,822,679 - 27,882,313 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105350   ⟹   ENSRNOP00000088338
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl227,822,679 - 27,882,313 (-)Ensembl
RefSeq Acc Id: NM_138516   ⟹   NP_612525
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2227,822,669 - 27,882,313 (-)NCBI
Rnor_6.0227,305,718 - 27,364,906 (-)NCBI
Rnor_5.0246,417,808 - 46,477,594 (-)NCBI
RGSC_v3.4226,952,022 - 27,012,088 (-)RGD
Celera223,868,651 - 23,928,707 (-)RGD
Sequence:
RefSeq Acc Id: XM_039101672   ⟹   XP_038957600
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2227,822,228 - 27,882,331 (-)NCBI
RefSeq Acc Id: XM_039101673   ⟹   XP_038957601
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2227,822,228 - 27,851,149 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_612525   ⟸   NM_138516
- UniProtKB: B2RYH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070520   ⟸   ENSRNOT00000091418
RefSeq Acc Id: ENSRNOP00000073092   ⟸   ENSRNOT00000078639
RefSeq Acc Id: XP_038957600   ⟸   XM_039101672
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038957601   ⟸   XM_039101673
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000088338   ⟸   ENSRNOT00000105350
RefSeq Acc Id: ENSRNOP00000092732   ⟸   ENSRNOT00000094510
Protein Domains
UBZ4-type   UmuC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K4L7-F1-model_v2 AlphaFold A0A0G2K4L7 1-852 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691090
Promoter ID:EPDNEW_R1607
Type:multiple initiation site
Name:Polk_1
Description:DNA polymerase kappa
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0227,364,923 - 27,364,983EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620058 AgrOrtholog
BioCyc Gene G2FUF-54779 BioCyc
Ensembl Genes ENSRNOG00000060626 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070520.2 UniProtKB/TrEMBL
  ENSRNOP00000073092 ENTREZGENE
  ENSRNOP00000073092.2 UniProtKB/TrEMBL
  ENSRNOP00000088338.1 UniProtKB/TrEMBL
  ENSRNOP00000092732.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078639 ENTREZGENE
  ENSRNOT00000078639.2 UniProtKB/TrEMBL
  ENSRNOT00000091418.2 UniProtKB/TrEMBL
  ENSRNOT00000094510.1 UniProtKB/TrEMBL
  ENSRNOT00000105350.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.100 UniProtKB/TrEMBL
  3.30.70.270 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934797 IMAGE-MGC_LOAD
InterPro DNA/RNA_pol_sf UniProtKB/TrEMBL
  DNA_pol_Y-fam_lit_finger_sf UniProtKB/TrEMBL
  DNA_pol_Y-fam_little_finger UniProtKB/TrEMBL
  DNA_repair_prot_UmuC-like UniProtKB/TrEMBL
  DNApol_IV UniProtKB/TrEMBL
  Rev_trsase/Diguanyl_cyclase UniProtKB/TrEMBL
  Znf_Rad18_put UniProtKB/TrEMBL
KEGG Report rno:171525 UniProtKB/TrEMBL
MGC_CLONE MGC:188557 IMAGE-MGC_LOAD
NCBI Gene 171525 ENTREZGENE
Pfam IMS UniProtKB/TrEMBL
  IMS_C UniProtKB/TrEMBL
PhenoGen Polk PhenoGen
PROSITE UMUC UniProtKB/TrEMBL
  ZF_UBZ4 UniProtKB/TrEMBL
SMART ZnF_Rad18 UniProtKB/TrEMBL
Superfamily-SCOP DNA_pol_Y-fam_little_finger UniProtKB/TrEMBL
  SSF56672 UniProtKB/TrEMBL
UniProt A0A0G2JY51_RAT UniProtKB/TrEMBL
  A0A0G2K4L7_RAT UniProtKB/TrEMBL
  A0A8I6A9L7_RAT UniProtKB/TrEMBL
  A0A8I6GKB4_RAT UniProtKB/TrEMBL
  B2RYH3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Polk  DNA polymerase kappa  Polk  polymerase (DNA) kappa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-09 Polk  polymerase (DNA) kappa  Polk  polymerase (DNA directed) kappa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Polk  polymerase (DNA directed) kappa      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Polk  polymerase (DNA directed) kappa      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease low expression in mammary carcinomas 724605