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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620058
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Polk
Name: DNA polymerase kappa
Acc ID: CHEBI:16311
Term: dCTP
Definition: A 2'-deoxycytidine phosphate having cytosine as the nucleobase.
Chemical ID: MESH:C024107
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Polkaffects bindingISORGD:13439986480464CTDPOLK protein binds to 2'-deoxycytidine 5'-triphosphate

PMID:31286773
Polkmultiple interactionsISORGD:13439986480464CTD2'-deoxycytidine 5'-triphosphate promotes the reaction [N2-furfuryl-deoxyguanosine results in increased stability of POLK protein] N-2'-deoxyguanosin-8-yl-3-aminobenzanthrone inhibits the reaction [POLK protein binds to 2'-deoxycytidine 5'-triphosphate]

PMID:28823149 PMID:31286773
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