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Gene: Thap1 (THAP domain containing 1) Rattus norvegicus
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Symbol: Thap1
Name: THAP domain containing 1
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; and zinc ion binding activity. Predicted to be involved in several processes, including endothelial cell proliferation; negative regulation of transcription by RNA polymerase II; and transcription, DNA-templated. Predicted to localize to fibrillar center and nucleoplasm. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP domain containing 1); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC306547; MGC105527; THAP domain containing, apoptosis associated protein 1; THAP domain-containing apoptosis-associated protein 1; THAP domain-containing protein 1
Orthologs:
Homo sapiens (human) : THAP1 (THAP domain containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Thap1 (THAP domain containing, apoptosis associated protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thap1 (THAP domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : THAP1 (THAP domain containing 1)
Canis lupus familiaris (dog) : THAP1 (THAP domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thap1 (THAP domain containing 1)
Sus scrofa (pig) : THAP1 (THAP domain containing 1)
Chlorocebus sabaeus (African green monkey) : THAP1 (THAP domain containing 1)
Heterocephalus glaber (naked mole-rat) : Thap1 (THAP domain containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01670,661,360 - 70,665,831 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1670,661,320 - 70,665,831 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,327,551 - 70,332,022 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,268,327 - 70,272,795 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11670,268,590 - 70,273,060 (-)NCBI
Celera1663,817,000 - 63,821,594 (-)NCBICelera
Cytogenetic Map16q12.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Thap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307589
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.