Srpk1 (SRSF protein kinase 1) - Rat Genome Database

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Gene: Srpk1 (SRSF protein kinase 1) Rattus norvegicus
Analyze
Symbol: Srpk1
Name: SRSF protein kinase 1
RGD ID: 1308272
Description: Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including regulation of mRNA processing; regulation of viral genome replication; and spliceosomal complex assembly. Predicted to be located in chromatin and nuclear speck. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK1 (SRSF protein kinase 1); INTERACTS WITH (+)-schisandrin B; acrylamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC361811; MGC116186; serine/arginine-rich protein specific kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8206,647,539 - 6,684,129 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl206,649,450 - 6,683,835 (-)EnsemblGRCr8
mRatBN7.2206,645,809 - 6,682,448 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl206,645,809 - 6,682,134 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx207,360,437 - 7,394,786 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0206,722,274 - 6,756,623 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,202,846 - 7,237,239 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,829,412 - 5,865,877 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,831,119 - 5,865,854 (-)Ensemblrn6Rnor6.0
Rnor_5.0207,866,852 - 7,901,153 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4206,829,410 - 6,870,877 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera208,203,854 - 8,238,077 (-)NCBICelera
RGSC_v3.1206,829,636 - 6,871,104 (-)NCBI
Cytogenetic Map20p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol AF  (ISO)
Butylbenzyl phthalate  (ISO)
butyric acid  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
decabromodiphenyl ether  (EXP)
Dibutyl phosphate  (ISO)
Diisodecyl phthalate  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
fenthion  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
isoflurane  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methidathion  (ISO)
N-nitrosodiethylamine  (EXP)
okadaic acid  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paraquat  (ISO)
protein kinase inhibitor  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sevoflurane  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA,ISO)
chromosome  (IEA)
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
nuclear body  (IEA)
nuclear matrix  (IEA)
nuclear speck  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8208298   PMID:9237760   PMID:9446799   PMID:11509566   PMID:12417631   PMID:12477932   PMID:15034300   PMID:20498328   PMID:22681889   PMID:28076779   PMID:30101479   PMID:33167866  


Genomics

Comparative Map Data
Srpk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8206,647,539 - 6,684,129 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl206,649,450 - 6,683,835 (-)EnsemblGRCr8
mRatBN7.2206,645,809 - 6,682,448 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl206,645,809 - 6,682,134 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx207,360,437 - 7,394,786 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0206,722,274 - 6,756,623 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,202,846 - 7,237,239 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,829,412 - 5,865,877 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,831,119 - 5,865,854 (-)Ensemblrn6Rnor6.0
Rnor_5.0207,866,852 - 7,901,153 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4206,829,410 - 6,870,877 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera208,203,854 - 8,238,077 (-)NCBICelera
RGSC_v3.1206,829,636 - 6,871,104 (-)NCBI
Cytogenetic Map20p12NCBI
SRPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38635,832,966 - 35,921,098 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl635,832,966 - 35,921,342 (-)Ensemblhg38GRCh38
GRCh37635,800,743 - 35,888,875 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36635,908,789 - 35,996,934 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34635,908,788 - 35,996,934NCBI
Celera637,355,384 - 37,443,522 (-)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef635,518,955 - 35,608,798 (-)NCBIHuRef
CHM1_1635,802,571 - 35,890,700 (-)NCBICHM1_1
T2T-CHM13v2.0635,653,298 - 35,741,415 (-)NCBIT2T-CHM13v2.0
Srpk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,806,622 - 28,841,795 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1728,806,622 - 28,841,683 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381728,587,648 - 28,622,528 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,587,648 - 28,622,709 (-)Ensemblmm10GRCm38
MGSCv371728,726,537 - 28,759,399 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361728,317,181 - 28,350,043 (-)NCBIMGSCv36mm8
Celera1729,143,627 - 29,176,732 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.78NCBI
Srpk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554373,664,290 - 3,729,834 (-)Ensembl
ChiLan1.0NW_0049554373,664,290 - 3,729,832 (-)NCBIChiLan1.0ChiLan1.0
SRPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2550,299,544 - 50,386,822 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1646,167,467 - 46,256,406 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0635,393,290 - 35,480,530 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1636,596,292 - 36,683,363 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl636,598,552 - 36,683,257 (-)EnsemblpanPan2panpan1.1
SRPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1124,941,292 - 5,029,580 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl124,917,297 - 5,030,255 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha124,956,320 - 5,050,126 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0125,283,163 - 5,377,056 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,285,510 - 5,377,171 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1124,938,758 - 5,032,561 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,017,870 - 5,111,606 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,118,941 - 5,211,812 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Srpk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494640,484,027 - 40,552,985 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647623,407,226 - 23,476,579 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647623,407,226 - 23,476,203 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl731,645,755 - 31,701,087 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1731,645,753 - 31,701,305 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2736,573,709 - 36,638,641 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11736,196,763 - 36,287,166 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1736,196,898 - 36,284,900 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604435,781,007 - 35,871,348 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srpk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475421,679,578 - 21,743,913 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475421,679,597 - 21,743,951 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Srpk1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1185,238,597 - 5,275,243 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Srpk1
242 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:46
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000000612
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362632310078622Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036263239244918Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
RH128309  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8206,649,357 - 6,649,546 (+)Marker Load Pipeline
mRatBN7.2206,647,627 - 6,647,816 (+)MAPPERmRatBN7.2
Rnor_6.0205,831,231 - 5,831,419NCBIRnor6.0
Rnor_5.0207,866,761 - 7,866,949UniSTSRnor5.0
RGSC_v3.4206,829,319 - 6,829,507UniSTSRGSC3.4
Celera208,203,763 - 8,203,951UniSTS
RH 3.4 Map2094.2UniSTS
Cytogenetic Map20p12UniSTS
BE120383  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2206,655,703 - 6,655,856 (+)MAPPERmRatBN7.2
Rnor_6.0205,839,313 - 5,839,465NCBIRnor6.0
Rnor_5.0207,874,765 - 7,874,917UniSTSRnor5.0
RGSC_v3.4206,843,594 - 6,843,746UniSTSRGSC3.4
Celera208,211,686 - 8,211,838UniSTS
RH 3.4 Map2077.33UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000000612   ⟹   ENSRNOP00000000612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl206,649,450 - 6,683,835 (-)Ensembl
mRatBN7.2 Ensembl206,645,809 - 6,682,098 (-)Ensembl
Rnor_6.0 Ensembl205,831,573 - 5,865,775 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl206,660,249 - 6,683,835 (-)Ensembl
mRatBN7.2 Ensembl206,658,519 - 6,682,134 (-)Ensembl
Rnor_6.0 Ensembl205,840,827 - 5,851,288 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092641   ⟹   ENSRNOP00000075811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl206,649,450 - 6,672,186 (-)Ensembl
mRatBN7.2 Ensembl206,645,809 - 6,670,457 (-)Ensembl
Rnor_6.0 Ensembl205,831,119 - 5,865,854 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100033   ⟹   ENSRNOP00000092552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl206,658,890 - 6,683,835 (-)Ensembl
mRatBN7.2 Ensembl206,657,493 - 6,682,134 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105949   ⟹   ENSRNOP00000076564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl206,649,450 - 6,671,828 (-)Ensembl
mRatBN7.2 Ensembl206,645,815 - 6,682,105 (-)Ensembl
RefSeq Acc Id: NM_001025726   ⟹   NP_001020897
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8206,649,449 - 6,683,835 (-)NCBI
mRatBN7.2206,647,719 - 6,682,107 (-)NCBI
Rnor_6.0205,831,322 - 5,865,854 (-)NCBI
Rnor_5.0207,866,852 - 7,901,153 (-)NCBI
RGSC_v3.4206,829,410 - 6,870,877 (-)RGD
Celera208,203,854 - 8,238,077 (-)RGD
Sequence:
RefSeq Acc Id: XM_039098821   ⟹   XP_038954749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8206,647,539 - 6,684,129 (-)NCBI
mRatBN7.2206,645,809 - 6,682,448 (-)NCBI
RefSeq Acc Id: NP_001020897   ⟸   NM_001025726
- UniProtKB: Q4KLN3 (UniProtKB/TrEMBL),   E9PTN4 (UniProtKB/TrEMBL),   A0A9K3Y6Q8 (UniProtKB/TrEMBL),   A0A0U1RRU0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075811   ⟸   ENSRNOT00000092641
Ensembl Acc Id: ENSRNOP00000000612   ⟸   ENSRNOT00000000612
RefSeq Acc Id: XP_038954749   ⟸   XM_039098821
- Peptide Label: isoform X1
- UniProtKB: A0A0U1RRU0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076564   ⟸   ENSRNOT00000105949
Ensembl Acc Id: ENSRNOP00000092552   ⟸   ENSRNOT00000100033
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0U1RRU0-F1-model_v2 AlphaFold A0A0U1RRU0 1-655 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701432
Promoter ID:EPDNEW_R11955
Type:initiation region
Name:Srpk1_1
Description:SRSF protein kinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,865,819 - 5,865,879EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308272 AgrOrtholog
BioCyc Gene G2FUF-4414 BioCyc
Ensembl Genes ENSRNOG00000000511 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000612 ENTREZGENE
  ENSRNOT00000000612.9 UniProtKB/TrEMBL
  ENSRNOT00000092514.3 UniProtKB/TrEMBL
  ENSRNOT00000092641.3 UniProtKB/TrEMBL
  ENSRNOT00000100033.2 UniProtKB/TrEMBL
  ENSRNOT00000105949.2 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7456350 IMAGE-MGC_LOAD
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
  SRPK UniProtKB/TrEMBL
KEGG Report rno:361811 UniProtKB/TrEMBL
MGC_CLONE MGC:116186 IMAGE-MGC_LOAD
NCBI Gene 361811 ENTREZGENE
PANTHER PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  SRSF PROTEIN KINASE 1 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Srpk1 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000511 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A0U1RRU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5XV63_RAT UniProtKB/TrEMBL
  A0A8I6AI43_RAT UniProtKB/TrEMBL
  A0A8I6AQC6_RAT UniProtKB/TrEMBL
  A0A9K3Y6Q8 ENTREZGENE, UniProtKB/TrEMBL
  E9PTN4 ENTREZGENE
  Q4KLN3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PTN4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Srpk1  SRSF protein kinase 1  Srpk1  SFRS protein kinase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-22 Srpk1  SFRS protein kinase 1  Srpk1  Srsf protein kinase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-13 Srpk1  Srsf protein kinase 1  Srpk1  SFRS protein kinase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Srpk1  SFRS protein kinase 1  Srpk1  serine/arginine-rich protein specific kinase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Srpk1  serine/arginine-rich protein specific kinase 1  Srpk1_predicted  serine/arginine-rich protein specific kinase 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Srpk1_predicted  serine/arginine-rich protein specific kinase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED