Anks1a (ankyrin repeat and sterile alpha motif domain containing 1A) - Rat Genome Database

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Gene: Anks1a (ankyrin repeat and sterile alpha motif domain containing 1A) Rattus norvegicus
Analyze
Symbol: Anks1a
Name: ankyrin repeat and sterile alpha motif domain containing 1A
RGD ID: 1309183
Description: Predicted to have ephrin receptor binding activity. Predicted to be involved in several processes, including ephrin receptor signaling pathway; negative regulation of ubiquitin-dependent protein catabolic process; and neuron remodeling. Predicted to localize to cytosol; neuron projection; and nucleoplasm. Orthologous to human ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A); INTERACTS WITH 6-propyl-2-thiouracil; aconitine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Anks1; ankyrin repeat and SAM domain containing 1; ankyrin repeat and SAM domain-containing protein 1A; LOC309639
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
Rnor_6.0 Ensembl207,484,550 - 7,636,497 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0207,484,550 - 7,636,498 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0209,686,580 - 9,840,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,121,316 - 6,274,822 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1206,121,537 - 6,273,689 (+)NCBI
Celera207,524,771 - 7,677,018 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,ISO)
neuron projection  (ISO)
nucleoplasm  (IEA,ISO)

Molecular Function

References

Additional References at PubMed
PMID:17875921   PMID:20100865  


Genomics

Comparative Map Data
Anks1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
Rnor_6.0 Ensembl207,484,550 - 7,636,497 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0207,484,550 - 7,636,498 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0209,686,580 - 9,840,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,121,316 - 6,274,822 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1206,121,537 - 6,273,689 (+)NCBI
Celera207,524,771 - 7,677,018 (+)NCBICelera
Cytogenetic Map20p12NCBI
ANKS1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl634,889,255 - 35,091,406 (+)EnsemblGRCh38hg38GRCh38
GRCh38634,889,255 - 35,097,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37634,857,032 - 35,059,183 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36634,965,016 - 35,167,168 (+)NCBINCBI36hg18NCBI36
Celera636,411,475 - 36,613,603 (+)NCBI
Cytogenetic Map6p21.31NCBI
HuRef634,579,837 - 34,781,340 (+)NCBIHuRef
CHM1_1634,859,101 - 35,061,139 (+)NCBICHM1_1
Anks1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,128,273 - 28,281,753 (+)NCBIGRCm39mm39
GRCm39 Ensembl1728,128,280 - 28,281,749 (+)Ensembl
GRCm381727,909,304 - 28,062,779 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,909,306 - 28,062,775 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,046,285 - 28,199,582 (+)NCBIGRCm37mm9NCBIm37
MGSCv361727,636,929 - 27,790,226 (+)NCBImm8
Celera1728,462,415 - 28,615,993 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
Anks1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554372,916,598 - 3,070,771 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554372,916,598 - 3,070,771 (+)NCBIChiLan1.0ChiLan1.0
ANKS1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1635,613,582 - 35,750,581 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl635,548,124 - 35,776,185 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0634,450,695 - 34,653,881 (+)NCBIMhudiblu_PPA_v0panPan3
ANKS1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1124,095,394 - 4,274,428 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl124,095,490 - 4,272,654 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha124,110,661 - 4,289,686 (+)NCBI
ROS_Cfam_1.0124,431,356 - 4,611,477 (+)NCBI
UMICH_Zoey_3.1124,091,532 - 4,270,545 (+)NCBI
UNSW_CanFamBas_1.0124,172,585 - 4,351,607 (+)NCBI
UU_Cfam_GSD_1.0124,272,622 - 4,451,697 (+)NCBI
Anks1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494639,759,615 - 39,865,169 (+)NCBI
SpeTri2.0NW_00493647624,093,838 - 24,200,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKS1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl730,812,920 - 30,995,361 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1730,812,925 - 30,995,369 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2735,661,335 - 35,766,115 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANKS1A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11737,036,665 - 37,229,906 (-)NCBI
ChlSab1.1 Ensembl1737,036,066 - 37,155,596 (-)Ensembl
Anks1a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475422,306,363 - 22,463,273 (-)NCBI

Position Markers
RH134403  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0207,636,201 - 7,636,406NCBIRnor6.0
Rnor_5.0209,840,642 - 9,840,847UniSTSRnor5.0
RGSC_v3.4206,274,526 - 6,274,731UniSTSRGSC3.4
Celera207,676,722 - 7,676,927UniSTS
RH 3.4 Map2074.84UniSTS
Cytogenetic Map20p12UniSTS
RH139847  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0207,578,290 - 7,578,500NCBIRnor6.0
Rnor_5.0209,782,452 - 9,782,662UniSTSRnor5.0
RGSC_v3.4206,216,589 - 6,216,799UniSTSRGSC3.4
Celera207,618,813 - 7,619,023UniSTS
RH 3.4 Map2059.8UniSTS
Cytogenetic Map20p12UniSTS
AW529418  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0207,594,978 - 7,595,144NCBIRnor6.0
Rnor_5.0209,799,140 - 9,799,306UniSTSRnor5.0
RGSC_v3.4206,233,277 - 6,233,443UniSTSRGSC3.4
Celera207,635,497 - 7,635,663UniSTS
RH 3.4 Map2061.5UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124652101Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125653396Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20126305996Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20126305996Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20127357423Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20128375393Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20128375393Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20128375393Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20128375393Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20128375393Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20133300419Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20137550487Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20137550487Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20201865447018654Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20299970747999707Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20340211127968216Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20403911318872273Rat
4889857Pur27Proteinuria QTL 2712.20.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20403911318872273Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)20410895649108956Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2048554689899946Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RChigh CD8 T cell count to CD45RClow CD8 T cell count ratio (CMO:0001990)20485546810800530Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20485547515050565Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20587544818739210Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:234
Count of miRNA genes:161
Interacting mature miRNAs:180
Transcripts:ENSRNOT00000044395
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 12 6 8 6 65 32 37 11
Low 2 45 35 11 35 8 11 9 3 4 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC132760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000044395   ⟹   ENSRNOP00000048981
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl207,484,550 - 7,636,497 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000081604   ⟹   ENSRNOP00000072237
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl207,484,800 - 7,636,497 (+)Ensembl
RefSeq Acc Id: NM_001107613   ⟹   NP_001101083
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,678 - 6,117,138 (+)NCBI
Rnor_6.0207,484,550 - 7,636,497 (+)NCBI
Rnor_5.0209,686,580 - 9,840,939 (+)NCBI
RGSC_v3.4206,121,316 - 6,274,822 (+)RGD
Celera207,524,771 - 7,677,018 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256193   ⟹   XP_006256255
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
Rnor_6.0207,484,574 - 7,636,498 (+)NCBI
Rnor_5.0209,686,580 - 9,840,939 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256195   ⟹   XP_006256257
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
Rnor_6.0207,484,555 - 7,636,498 (+)NCBI
Rnor_5.0209,686,580 - 9,840,939 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256196   ⟹   XP_006256258
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
Rnor_6.0207,484,574 - 7,636,498 (+)NCBI
Rnor_5.0209,686,580 - 9,840,939 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256197   ⟹   XP_006256259
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
Rnor_6.0207,484,555 - 7,636,498 (+)NCBI
Rnor_5.0209,686,580 - 9,840,939 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772813   ⟹   XP_008771035
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
Rnor_6.0207,484,574 - 7,636,498 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772814   ⟹   XP_008771036
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0207,565,620 - 7,636,498 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772815   ⟹   XP_008771037
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0207,584,358 - 7,636,498 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601643   ⟹   XP_017457132
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0207,616,720 - 7,636,498 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098683   ⟹   XP_038954611
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
RefSeq Acc Id: XM_039098684   ⟹   XP_038954612
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
RefSeq Acc Id: XM_039098685   ⟹   XP_038954613
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
RefSeq Acc Id: XM_039098686   ⟹   XP_038954614
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,117,139 (+)NCBI
RefSeq Acc Id: XM_039098687   ⟹   XP_038954615
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,114,601 (+)NCBI
RefSeq Acc Id: XM_039098688   ⟹   XP_038954616
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,963,658 - 6,114,601 (+)NCBI
RefSeq Acc Id: XM_039098689   ⟹   XP_038954617
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2206,040,367 - 6,117,139 (+)NCBI
RefSeq Acc Id: XM_039098690   ⟹   XP_038954618
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2206,097,374 - 6,117,139 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101083   ⟸   NM_001107613
- UniProtKB: D4AC12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256255   ⟸   XM_006256193
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006256257   ⟸   XM_006256195
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006256258   ⟸   XM_006256196
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006256259   ⟸   XM_006256197
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_008771035   ⟸   XM_008772813
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_008771036   ⟸   XM_008772814
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008771037   ⟸   XM_008772815
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017457132   ⟸   XM_017601643
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000072237   ⟸   ENSRNOT00000081604
RefSeq Acc Id: ENSRNOP00000048981   ⟸   ENSRNOT00000044395
RefSeq Acc Id: XP_038954611   ⟸   XM_039098683
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038954612   ⟸   XM_039098684
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038954614   ⟸   XM_039098686
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038954613   ⟸   XM_039098685
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038954615   ⟸   XM_039098687
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038954616   ⟸   XM_039098688
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038954617   ⟸   XM_039098689
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038954618   ⟸   XM_039098690
- Peptide Label: isoform X13
Protein Domains
ANK_REP_REGION   PID   SAM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701470
Promoter ID:EPDNEW_R11979
Type:multiple initiation site
Name:Anks1a_1
Description:ankyrin repeat and sterile alpha motif domain containing 1A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0207,484,754 - 7,484,814EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 6256954 6256955 A G snv ACI/EurMcwi (MCW), SS/JrHsdMcwi (MCW), SR/JrHsd (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309183 AgrOrtholog
Ensembl Genes ENSRNOG00000000498 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000048981 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072237 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044395 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000081604 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ANKS1A UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_dom UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  PTyr_interaction_dom UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM_ANKS1_repeat1 UniProtKB/TrEMBL
  SAM_ANKS1_repeat2 UniProtKB/TrEMBL
  SAM_type UniProtKB/TrEMBL
KEGG Report rno:309639 UniProtKB/TrEMBL
NCBI Gene 309639 ENTREZGENE
PANTHER PTHR24174:SF4 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
PhenoGen Anks1a PhenoGen
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  PTB UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
  SAM_homology UniProtKB/TrEMBL
UniProt A0A0G2K2G7_RAT UniProtKB/TrEMBL
  D4AC12 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-26 Anks1a  ankyrin repeat and sterile alpha motif domain containing 1A  Anks1  ankyrin repeat and SAM domain containing 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Anks1  ankyrin repeat and SAM domain containing 1   Anks1_predicted  ankyrin repeat and SAM domain containing 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Anks1_predicted  ankyrin repeat and SAM domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED