Bdh2 (3-hydroxybutyrate dehydrogenase 2) - Rat Genome Database

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Gene: Bdh2 (3-hydroxybutyrate dehydrogenase 2) Rattus norvegicus
Analyze
Symbol: Bdh2
Name: 3-hydroxybutyrate dehydrogenase 2
RGD ID: 1309898
Description: Predicted to enable 3-hydroxybutyrate dehydrogenase activity; NAD binding activity; and oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Predicted to be involved in several processes, including fatty acid beta-oxidation; heme metabolic process; and siderophore biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human BDH2 (3-hydroxybutyrate dehydrogenase 2); PARTICIPATES IN butanoate metabolic pathway; ketone bodies metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 3-hydroxybutyrate dehydrogenase, type 2; 4-oxo-L-proline reductase; dehydrogenase/reductase (SDR family) member 6; dehydrogenase/reductase SDR family member 6; Dhrs6; LOC295458; oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; short chain dehydrogenase/reductase family 15C member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22223,702,410 - 223,723,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2223,702,412 - 223,723,072 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2231,428,579 - 231,449,290 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02229,328,317 - 229,349,029 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02224,193,101 - 224,213,813 (+)NCBIRnor_WKY
Rnor_6.02240,461,505 - 240,482,149 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2240,461,505 - 240,482,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02258,981,008 - 259,001,652 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42232,765,049 - 232,785,694 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12232,751,789 - 232,772,438 (+)NCBI
Celera2215,916,820 - 215,937,360 (+)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
cisplatin  (EXP,ISO)
clofibric acid  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
ferric oxide  (ISO)
gentamycin  (EXP)
glutathione  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
melatonin  (ISO)
menadione  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nickel atom  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorobutanesulfonic acid  (ISO)
perfluorodecanoic acid  (ISO)
perfluorododecanoic acid  (ISO)
perfluoroheptanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanesulfonamide  (ISO)
perfluorooctanoic acid  (ISO)
perfluoroundecanoic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (ISO)
mitochondrion  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16380372   PMID:19056867   PMID:20550936   PMID:21492153   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Bdh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22223,702,410 - 223,723,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2223,702,412 - 223,723,072 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2231,428,579 - 231,449,290 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02229,328,317 - 229,349,029 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02224,193,101 - 224,213,813 (+)NCBIRnor_WKY
Rnor_6.02240,461,505 - 240,482,149 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2240,461,505 - 240,482,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02258,981,008 - 259,001,652 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42232,765,049 - 232,785,694 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12232,751,789 - 232,772,438 (+)NCBI
Celera2215,916,820 - 215,937,360 (+)NCBICelera
Cytogenetic Map2q43NCBI
BDH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384103,077,592 - 103,099,834 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4103,077,592 - 103,099,870 (-)EnsemblGRCh38hg38GRCh38
GRCh374103,998,749 - 104,020,991 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364104,218,231 - 104,240,473 (-)NCBINCBI36Build 36hg18NCBI36
Celera4101,295,921 - 101,318,163 (-)NCBICelera
Cytogenetic Map4q24NCBI
HuRef499,732,546 - 99,754,789 (-)NCBIHuRef
CHM1_14103,975,255 - 103,997,497 (-)NCBICHM1_1
T2T-CHM13v2.04106,389,483 - 106,411,725 (-)NCBIT2T-CHM13v2.0
Bdh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393134,986,982 - 135,010,187 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3134,986,982 - 135,010,187 (+)EnsemblGRCm39 Ensembl
GRCm383135,281,221 - 135,304,426 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3135,281,221 - 135,304,426 (+)EnsemblGRCm38mm10GRCm38
MGSCv373134,944,185 - 134,967,390 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363135,218,676 - 135,241,813 (+)NCBIMGSCv36mm8
Celera3141,694,433 - 141,718,218 (+)NCBICelera
Cytogenetic Map3G3NCBI
Bdh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554965,518,245 - 5,538,669 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554965,518,403 - 5,534,325 (+)NCBIChiLan1.0ChiLan1.0
BDH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14106,157,222 - 106,179,402 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4106,157,229 - 106,179,402 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0495,533,173 - 95,556,000 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
BDH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13224,420,946 - 24,442,384 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3224,420,951 - 24,442,384 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3217,581,653 - 17,602,872 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03224,640,839 - 24,662,068 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3224,639,425 - 24,662,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13224,657,860 - 24,679,047 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03224,400,980 - 24,422,392 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03215,440,292 - 15,461,512 (+)NCBIUU_Cfam_GSD_1.0
Bdh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530116,934,971 - 16,961,073 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936520278,435 - 304,770 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936520278,467 - 304,525 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BDH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8117,969,998 - 117,995,215 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18117,969,913 - 117,995,219 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28126,942,580 - 126,966,446 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BDH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1751,185,303 - 51,206,300 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl751,183,107 - 51,206,261 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603729,696,953 - 29,718,299 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bdh2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248304,991,714 - 5,006,783 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248304,991,689 - 5,006,911 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bdh2
173 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:97
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000019507
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
1359019Hrtrt19Heart rate QTL 192.9heart pumping trait (VT:2000009)heart rate (CMO:0000002)2219753301226277316Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat

Markers in Region
AI013944  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22223,715,445 - 223,715,568 (+)MAPPERmRatBN7.2
Rnor_6.02240,474,519 - 240,474,641NCBIRnor6.0
Rnor_5.02258,994,022 - 258,994,144UniSTSRnor5.0
RGSC_v3.42232,778,069 - 232,778,191UniSTSRGSC3.4
Celera2215,929,735 - 215,929,857UniSTS
RH 3.4 Map21561.2UniSTS
Cytogenetic Map2q43UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 17 2 2 2 8 35 31 2
Low 3 26 55 39 19 39 8 11 66 10 9 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019507   ⟹   ENSRNOP00000019507
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2223,702,412 - 223,723,072 (+)Ensembl
Rnor_6.0 Ensembl2240,461,505 - 240,482,145 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095079   ⟹   ENSRNOP00000088377
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2223,702,412 - 223,720,275 (+)Ensembl
RefSeq Acc Id: NM_001106473   ⟹   NP_001099943
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22223,702,412 - 223,723,072 (+)NCBI
Rnor_6.02240,461,505 - 240,482,145 (+)NCBI
Rnor_5.02258,981,008 - 259,001,652 (+)NCBI
RGSC_v3.42232,765,049 - 232,785,694 (+)RGD
Celera2215,916,820 - 215,937,360 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233322   ⟹   XP_006233384
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22223,702,410 - 223,723,076 (+)NCBI
Rnor_6.02240,461,517 - 240,482,149 (+)NCBI
Rnor_5.02258,981,008 - 259,001,652 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001099943 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233384 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D4A1J4 (Get FASTA)   NCBI Sequence Viewer  
  EDL82248 (Get FASTA)   NCBI Sequence Viewer  
  EDL82249 (Get FASTA)   NCBI Sequence Viewer  
  EDL82250 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001099943   ⟸   NM_001106473
- UniProtKB: D4A1J4 (UniProtKB/Swiss-Prot),   A0A0A0MXX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233384   ⟸   XM_006233322
- Peptide Label: isoform X1
- UniProtKB: D4A1J4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000019507   ⟸   ENSRNOT00000019507
RefSeq Acc Id: ENSRNOP00000088377   ⟸   ENSRNOT00000095079

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1J4-F1-model_v2 AlphaFold D4A1J4 1-245 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691767
Promoter ID:EPDNEW_R2292
Type:initiation region
Name:Bdh2_1
Description:3-hydroxybutyrate dehydrogenase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02240,461,561 - 240,461,621EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309898 AgrOrtholog
BioCyc Gene G2FUF-51143 BioCyc
BioCyc Pathway PWY66-367 [ketogenesis] BioCyc
  PWY66-368 [ketolysis] BioCyc
Ensembl Genes ENSRNOG00000014490 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000019507 ENTREZGENE
  ENSRNOP00000019507.4 UniProtKB/TrEMBL
  ENSRNOP00000088377.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019507 ENTREZGENE
  ENSRNOT00000019507.6 UniProtKB/TrEMBL
  ENSRNOT00000095079.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:295458 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 295458 ENTREZGENE
PANTHER 3-HYDROXYBUTYRATE DEHYDROGENASE TYPE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIHYDROANTICAPSIN 7-DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam adh_short_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bdh2 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MXX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7Z5_RAT UniProtKB/TrEMBL
  BDH2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-03 Bdh2  3-hydroxybutyrate dehydrogenase 2  Bdh2  3-hydroxybutyrate dehydrogenase, type 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Bdh2  3-hydroxybutyrate dehydrogenase, type 2   Bdh2_predicted  3-hydroxybutyrate dehydrogenase, type 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Bdh2_predicted  3-hydroxybutyrate dehydrogenase, type 2 (predicted)  Dhrs6_predicted  dehydrogenase/reductase (SDR family) member 6 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Dhrs6_predicted  dehydrogenase/reductase (SDR family) member 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED